Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory development

Beneficial effects of Coomassie staining on proteomic analysis employing PAGE separation followed with whole-gel slicing, in-gel digestion and quantitative LC-MS/MS

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Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation

(2018) Brenda Raud et al.   Cell Metabolism

Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance

(2018) Mini P. Sajan et al.   CELLULAR SIGNALLING

Fatty acid metabolism in CD8+ T cell memory: Challenging current concepts

(2018) Brenda Raud et al.   IMMUNOLOGICAL REVIEWS

Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+T cells

(2017) Arnaud Delpoux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

(2017) Youdong Pan et al.   NATURE

A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells

(2017) Ruihua Ma et al.   NATURE CELL BIOLOGY

Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate

(2017) Chun-Kai Huang et al.   Nature Communications

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy

(2016) Madhusudhanan Sukumar et al.   Cell Metabolism

4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8+ T cell proliferation

(2016) Beom K Choi et al.   Cellular & Molecular Immunology

Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation

(2016) Zhongyu Xie et al.   MOLECULAR CELL

Structure of p300 in complex with acyl-CoA variants

(2016) Zuzanna Kaczmarska et al.   Nature Chemical Biology

Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner

(2016) Lianjun Zhang et al.   Cell Reports

ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch

(2016) Steven Zhao et al.   Cell Reports

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

(2013) Madhusudhanan Sukumar et al.   JOURNAL OF CLINICAL INVESTIGATION

FoxO1 Controls Effector-to-Memory Transition and Maintenance of Functional CD8 T Cell Memory

(2013) M. M. Tejera et al.   JOURNAL OF IMMUNOLOGY

Ketone bodies as signaling metabolites

(2013) John C. Newman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation

(2012) Rajesh R. Rao et al.   IMMUNITY

Suppression of Oxidative Stress by  -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

(2012) T. Shimazu et al.   SCIENCE

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

(2011) Gerritje J.W. van der Windt et al.   IMMUNITY

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL