New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond
出版年份 2015 全文链接
标题
New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond
作者
关键词
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出版物
FEBS Journal
Volume 282, Issue 4, Pages 647-672
出版商
Wiley
发表日期
2014-12-13
DOI
10.1111/febs.13175
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch
- (2014) Paul Cohen et al. CELL
- Targeting Mitochondrial Biogenesis to Treat Insulin Resistance
- (2014) Monica Zamora et al. CURRENT PHARMACEUTICAL DESIGN
- PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease
- (2014) Magali Dumont et al. FASEB JOURNAL
- PGC-1 Coactivator Activity Is Required for Murine Erythropoiesis
- (2014) S. Cui et al. MOLECULAR AND CELLULAR BIOLOGY
- Muscle-Specific SIRT1 Gain-of-Function Increases Slow-Twitch Fibers and Ameliorates Pathophysiology in a Mouse Model of Duchenne Muscular Dystrophy
- (2014) Angeliki Chalkiadaki et al. PLoS Genetics
- Post-natal induction of PGC-1α protects against severe muscle dystrophy independently of utrophin
- (2014) Mun Chan et al. Skeletal Muscle
- Metabolic Stress Modulates Alzheimer’s β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons
- (2013) Ruishan Wang et al. Cell Metabolism
- A Role for Peroxisome Proliferator-Activated Receptor γ Coactivator-1 in the Control of Mitochondrial Dynamics During Postnatal Cardiac Growth
- (2013) Ola J. Martin et al. CIRCULATION RESEARCH
- Mitochondrial Diseases of the Brain
- (2013) Rajnish K. Chaturvedi et al. FREE RADICAL BIOLOGY AND MEDICINE
- A Role for Peroxisome Proliferator-activated Receptor γ Coactivator 1 (PGC-1) in the Regulation of Cardiac Mitochondrial Phospholipid Biosynthesis
- (2013) Ling Lai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A complex interplay between PGC-1 co-activators and mTORC1 regulates hematopoietic recovery following 5-fluorouracil treatment
- (2013) Sunanda Basu Stem Cell Research
- Peroxisome Proliferator-Activated-γ Coactivator-1α–Mediated Mitochondrial Biogenesis Is Important for Hematopoietic Recovery in Response to Stress
- (2013) Sunanda Basu et al. STEM CELLS AND DEVELOPMENT
- Disconnecting Mitochondrial Content from Respiratory Chain Capacity in PGC-1-Deficient Skeletal Muscle
- (2013) Glenn C. Rowe et al. Cell Reports
- PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner
- (2013) Kari T. Chambers et al. Molecular Metabolism
- Mice lacking PGC-1β in adipose tissues reveal a dissociation between mitochondrial dysfunction and insulin resistance
- (2013) Natàlia Enguix et al. Molecular Metabolism
- A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy
- (2012) Jorge L. Ruas et al. CELL
- Elevated PGC-1α Activity Sustains Mitochondrial Biogenesis and Muscle Function without Extending Survival in a Mouse Model of Inherited ALS
- (2012) Sandrine Da Cruz et al. Cell Metabolism
- Peri-implantation lethality in mice lacking the PGC-1-related coactivator protein
- (2012) Xin He et al. DEVELOPMENTAL DYNAMICS
- FGF21 regulates PGC-1 and browning of white adipose tissues in adaptive thermogenesis
- (2012) f. M. Fisher et al. GENES & DEVELOPMENT
- Sustained expression of PGC-1 in the rat nigrostriatal system selectively impairs dopaminergic function
- (2012) C. Ciron et al. HUMAN MOLECULAR GENETICS
- NT-PGC-1α Protein Is Sufficient to Link β3-Adrenergic Receptor Activation to Transcriptional and Physiological Components of Adaptive Thermogenesis
- (2012) Ji Suk Chang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PGC-1α Determines Light Damage Susceptibility of the Murine Retina
- (2012) Anna Egger et al. PLoS One
- Rescue of Dystrophic Skeletal Muscle by PGC-1α Involves a Fast to Slow Fiber Type Shift in the mdx Mouse
- (2012) Joshua T. Selsby et al. PLoS One
- PGC-1α is Dispensable for Exercise-Induced Mitochondrial Biogenesis in Skeletal Muscle
- (2012) Glenn C. Rowe et al. PLoS One
- Liver-Specific PGC-1beta Deficiency Leads to Impaired Mitochondrial Function and Lipogenic Response to Fasting-Refeeding
- (2012) Kari T. Chambers et al. PLoS One
- Skeletal muscle transcriptional coactivator PGC-1 mediates mitochondrial, but not metabolic, changes during calorie restriction
- (2012) L. W. S. Finley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of insulin resistance in mice lacking PGC-1 in adipose tissues
- (2012) S. Kleiner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes
- (2011) Andrew Philp et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Association of PGC-1alphapolymorphisms with age of onset and risk of Parkinson's disease
- (2011) Joanne Clark et al. BMC Medical Genetics
- PGC1 Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis
- (2011) K. Bhalla et al. CANCER RESEARCH
- Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease
- (2011) Giuseppa Mudò et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy
- (2011) Christian Riehle et al. CIRCULATION RESEARCH
- Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress
- (2011) L. E. Wright et al. DIABETOLOGIA
- Separation of the gluconeogenic and mitochondrial functions of PGC-1 through S6 kinase
- (2011) Y. Lustig et al. GENES & DEVELOPMENT
- PGC-1-related Coactivator (PRC), a Sensor of Metabolic Stress, Orchestrates a Redox-sensitive Program of Inflammatory Gene Expression
- (2011) Natalie Gleyzer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exercise Increases Mitochondrial PGC-1α Content and Promotes Nuclear-Mitochondrial Cross-talk to Coordinate Mitochondrial Biogenesis
- (2011) Adeel Safdar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis
- (2011) Wei Zhao et al. Molecular Neurodegeneration
- Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease
- (2011) Hong Van B Che et al. Molecular Neurodegeneration
- Rosiglitazone-Induced Mitochondrial Biogenesis in White Adipose Tissue Is Independent of Peroxisome Proliferator-Activated Receptor γ Coactivator-1α
- (2011) Rosario Pardo et al. PLoS One
- Peroxisome proliferator-activated receptor- coactivator 1- (PGC1 ) is a metabolic regulator of intestinal epithelial cell fate
- (2011) I. D'Errico et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptional Control of the ERBB2 Amplicon by ERR and PGC-1 Promotes Mammary Gland Tumorigenesis
- (2010) G. Deblois et al. CANCER RESEARCH
- Transcriptional Control of Brown Fat Development
- (2010) Shingo Kajimura et al. Cell Metabolism
- Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity
- (2010) Christoph Zechner et al. Cell Metabolism
- miR-378 ∗ Mediates Metabolic Shift in Breast Cancer Cells via the PGC-1β/ERRγ Transcriptional Pathway
- (2010) Lillian J. Eichner et al. Cell Metabolism
- Defective DNA Replication Impairs Mitochondrial Biogenesis In Human Failing Hearts
- (2010) Georgios Karamanlidis et al. CIRCULATION RESEARCH
- Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1α) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats
- (2010) C. R. Benton et al. DIABETOLOGIA
- Estrogen-related receptor α and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria
- (2010) Delphine Mirebeau-Prunier et al. FEBS Journal
- Ubiquitin Proteasome-dependent Degradation of the Transcriptional Coactivator PGC-1α via the N-terminal Pathway
- (2010) Julie Trausch-Azar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of NT-PGC-1α Subcellular Localization and Function by Protein Kinase A-dependent Modulation of Nuclear Export by CRM1
- (2010) Ji Suk Chang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α) and Sirtuin 1 (SIRT1) Reside in Mitochondria
- (2010) Katia Aquilano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PGC-1β-Regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERRα
- (2010) Di Shao et al. MITOCHONDRION
- microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma
- (2010) Julja Burchard et al. Molecular Systems Biology
- PGC-1 , A Potential Therapeutic Target for Early Intervention in Parkinson's Disease
- (2010) B. Zheng et al. Science Translational Medicine
- The role of PGC-1α on mitochondrial function and apoptotic susceptibility in muscle
- (2009) Peter J. Adhihetty et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- PGC-1α plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle
- (2009) Tuoyu Geng et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia
- (2009) Weiping Qin et al. ARCHIVES OF NEUROLOGY
- Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density
- (2009) Romain Barrès et al. Cell Metabolism
- The Role of Peroxisome Proliferator-Activated Receptor γ Coactivator-1 β in the Pathogenesis of Fructose-Induced Insulin Resistance
- (2009) Yoshio Nagai et al. Cell Metabolism
- Control by Circulating Factors of Mitochondrial Function and Transcription Cascade in Heart Failure
- (2009) Anne Garnier et al. Circulation-Heart Failure
- Tissue-Specific Remodeling of the Mitochondrial Proteome in Type 1 Diabetic Akita Mice
- (2009) H. Bugger et al. DIABETES
- GCN5-mediated Transcriptional Control of the Metabolic Coactivator PGC-1β through Lysine Acetylation
- (2009) Timothy J. Kelly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alternative mRNA Splicing Produces a Novel Biologically Active Short Isoform of PGC-1α
- (2009) Yubin Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The gene coding for PGC-1α modifies age at onset in Huntington's Disease
- (2009) Patrick Weydt et al. Molecular Neurodegeneration
- Increased muscle PGC-1 expression protects from sarcopenia and metabolic disease during aging
- (2009) T. Wenz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle
- (2009) Jessica Chinsomboon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The transcriptional coactivator PGC-1α is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis
- (2008) John J. Lehman et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- RETRACTED: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy Phenotype
- (2008) Tina Wenz et al. Cell Metabolism
- Genome-wide Coactivation Analysis of PGC-1α Identifies BAF60a as a Regulator of Hepatic Lipid Metabolism
- (2008) Siming Li et al. Cell Metabolism
- Transcriptional coactivators PGC-1 and PGC-l control overlapping programs required for perinatal maturation of the heart
- (2008) L. Lai et al. GENES & DEVELOPMENT
- SCFCdc4 acts antagonistically to the PGC-1 transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis
- (2008) B. L. Olson et al. GENES & DEVELOPMENT
- PGC-1-related Coactivator Complexes with HCF-1 and NRF-2β in Mediating NRF-2(GABP)-dependent Respiratory Gene Expression
- (2008) Kristel Vercauteren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Short Hairpin RNA-mediated Silencing of PRC (PGC-1-related Coactivator) Results in a Severe Respiratory Chain Deficiency Associated with the Proliferation of Aberrant Mitochondria
- (2008) Kristel Vercauteren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PGC-1α and ERRα target gene downregulation is a signature of the failing human heart
- (2008) Smita Sihag et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
- (2008) Zoltan Arany et al. NATURE
- Paradoxical effects of increased expression of PGC-1 on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism
- (2008) C. S. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PGC-1α is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle
- (2007) Lotte Leick et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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