Direct Type I IFN but Not MDA5/TLR3 Activation of Dendritic Cells Is Required for Maturation and Metabolic Shift to Glycolysis after Poly IC Stimulation
出版年份 2014 全文链接
标题
Direct Type I IFN but Not MDA5/TLR3 Activation of Dendritic Cells Is Required for Maturation and Metabolic Shift to Glycolysis after Poly IC Stimulation
作者
关键词
Interferons, T cells, Cytokines, Gene expression, Inflammation, Mitochondria, Antigens, Immune receptor signaling
出版物
PLOS BIOLOGY
Volume 12, Issue 1, Pages e1001759
出版商
Public Library of Science (PLoS)
发表日期
2014-01-08
DOI
10.1371/journal.pbio.1001759
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Role of hypoxia inducible factor-1α for interferon synthesis in mouse dendritic cells
- (2013) Regina Wobben et al. BIOLOGICAL CHEMISTRY
- HIF-1α influences myeloid cell antigen presentation and response to subcutaneous OVA vaccination
- (2013) Tamara Bhandari et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
- (2012) B. Everts et al. BLOOD
- PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+T cells
- (2012) David K. Finlay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A diverse range of gene products are effectors of the type I interferon antiviral response
- (2011) John W. Schoggins et al. NATURE
- The Depolarizing Action of GABA in Cultured Hippocampal Neurons Is Not Due to the Absence of Ketone Bodies
- (2011) Jaylyn Waddell et al. PLoS One
- Direct activation of antigen-presenting cells is required for CD8+ T-cell priming and tumor vaccination
- (2011) W. Kratky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
- (2010) C. M. Krawczyk et al. BLOOD
- Inflammatory cytokines as a third signal for T cell activation
- (2010) Julie M Curtsinger et al. CURRENT OPINION IN IMMUNOLOGY
- Neutralization of IL-4 reverses the nonresponsiveness of CD4+ T cells to regulatory T-cell induction in non-responder mouse strains
- (2010) Jun Wang et al. MOLECULAR IMMUNOLOGY
- Effects of TLR Agonists on the Hypoxia-Regulated Transcription Factor HIF-1α and Dendritic Cell Maturation under Normoxic Conditions
- (2010) Rolf Spirig et al. PLoS One
- Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-α/β, IFN-γ, and IFN-λ in host defense
- (2009) Shen-Ying Zhang et al. IMMUNOLOGICAL REVIEWS
- Dendritic cells require a systemic type I interferon response to mature and induce CD4+Th1 immunity with poly IC as adjuvant
- (2009) M. Paula Longhi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Strategies for recruiting and targeting dendritic cells for optimizing HIV vaccines
- (2009) Jeffrey D. Ahlers et al. TRENDS IN MOLECULAR MEDICINE
- Divergent effects of hypoxia on dendritic cell functions
- (2008) A. Mancino et al. BLOOD
- Generation of functionally mature dendritic cells from elutriated monocytes using polyinosinic : polycytidylic acid and soluble CD40 ligand for clinical application
- (2008) S. Kim et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Dendritic cell vaccines in melanoma: From promise to proof?
- (2008) W.J. Lesterhuis et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Inflammatory signals in dendritic cell activation and the induction of adaptive immunity
- (2008) Olivier Joffre et al. IMMUNOLOGICAL REVIEWS
- Small interfering RNA (siRNA) delivery into murine bone marrow-derived dendritic cells by electroporation
- (2008) Jonathan Jantsch et al. JOURNAL OF IMMUNOLOGICAL METHODS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now