The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
出版年份 2015 全文链接
标题
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
作者
关键词
-
出版物
NATURE MEDICINE
Volume 21, Issue 3, Pages 263-269
出版商
Springer Nature
发表日期
2015-02-17
DOI
10.1038/nm.3804
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
- (2014) Alvin Lu et al. CELL
- Mechanisms and Functions of Inflammasomes
- (2014) Mohamed Lamkanfi et al. CELL
- Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- (2014) Nagendra Singh et al. IMMUNITY
- Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile
- (2013) Evi M. Mercken et al. AGING CELL
- Ketone body metabolism and cardiovascular disease
- (2013) David G. Cotter et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging
- (2013) Yun-Hee Youm et al. Cell Metabolism
- Mechanisms of NOD-like Receptor-Associated Inflammasome Activation
- (2013) Haitao Wen et al. IMMUNITY
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- Impact of Peripheral Ketolytic Deficiency on Hepatic Ketogenesis and Gluconeogenesis during the Transition to Birth
- (2013) David G. Cotter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- How Metabolism Generates Signals during Innate Immunity and Inflammation
- (2013) Anne F. McGettrick et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
- (2013) Takuma Misawa et al. NATURE IMMUNOLOGY
- Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
- (2013) J. A. Hagar et al. SCIENCE
- Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
- (2013) N. Kayagaki et al. SCIENCE
- Ketone bodies as signaling metabolites
- (2013) John C. Newman et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The ketone body β-hydroxybutyric acid influences agouti-related peptide expression via AMP-activated protein kinase in hypothalamic GT1-7 cells
- (2012) Thomas Laeger et al. JOURNAL OF ENDOCRINOLOGY
- NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
- (2012) Paras K. Anand et al. NATURE
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- Suppression of Oxidative Stress by -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
- (2012) T. Shimazu et al. SCIENCE
- The ketogenic diet: metabolic influences on brain excitability and epilepsy
- (2012) Andrew Lutas et al. TRENDS IN NEUROSCIENCES
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- Pathogen-associated molecular patterns on biomaterials: a paradigm for engineering new vaccines
- (2011) Stacey L. Demento et al. TRENDS IN BIOTECHNOLOGY
- Cutting Edge: Critical Role for PYCARD/ASC in the Development of Experimental Autoimmune Encephalomyelitis
- (2010) P. J. Shaw et al. JOURNAL OF IMMUNOLOGY
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
- (2010) Seth L Masters et al. NATURE IMMUNOLOGY
- The Inflammasomes: Guardians of the Body
- (2009) Fabio Martinon et al. Annual Review of Immunology
- Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity
- (2009) Susannah D. Brydges et al. IMMUNITY
- The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
- (2009) Luigi Franchi et al. NATURE IMMUNOLOGY
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