Repression of Transcriptional Activity of Forkhead Box O1 by Histone Deacetylase Inhibitors Ameliorates Hyperglycemia in Type 2 Diabetic Rats

Valproate induced hepatic steatosis by enhanced fatty acid uptake and triglyceride synthesis

(2017) Xupeng Bai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metabolomics reveals the protective of Dihydromyricetin on glucose homeostasis by enhancing insulin sensitivity

(2016) Liang Le et al.   Scientific Reports

Diabetes

(2015) David M. Nathan   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Molecular pathophysiology of hepatic glucose production

(2015) Kfir Sharabi et al.   MOLECULAR ASPECTS OF MEDICINE

Histone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor

(2015) Hae-Ahm Lee et al.   PLoS One

Regulation of hepatic TRB3/Akt interaction induced by physical exercise and its effect on the hepatic glucose production in an insulin resistance state

(2015) Rodolfo Marinho et al.   Diabetology & Metabolic Syndrome

Continual evolution of type 2 diabetes: an update on pathophysiology and emerging treatment options

(2015) Susan Cornell   Therapeutics and Clinical Risk Management

Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia

(2015) Klaus G. Parhofer   Diabetes & Metabolism Journal

Control of hepatic glucose metabolism by islet and brain

(2014) J. M. Rojas et al.   DIABETES OBESITY & METABOLISM

Tissue-specific insulin signaling in the regulation of metabolism and aging

(2014) Jingjing Zhang et al.   IUBMB LIFE

USP7 Attenuates Hepatic Gluconeogenesis Through Modulation of FoxO1 Gene Promoter Occupancy

(2014) Jessica A. Hall et al.   MOLECULAR ENDOCRINOLOGY

Histone Deacetylase Inhibition Attenuates Transcriptional Activity of Mineralocorticoid Receptor Through Its Acetylation and Prevents Development of Hypertension

(2013) Hae-Ahm Lee et al.   CIRCULATION RESEARCH

Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells

(2013) Isabel Cordero-Herrera et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

(2012) A. Galmozzi et al.   DIABETES

By the numbers: New estimates from the IDF Diabetes Atlas Update for 2012

(2012) Leonor Guariguata   DIABETES RESEARCH AND CLINICAL PRACTICE

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

(2012) Mingjian Lu et al.   NATURE MEDICINE

Dietary Regulation of Histone Acetylases and Deacetylases for the Prevention of Metabolic Diseases

(2012) Tho Pham et al.   Nutrients

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

(2011) Maria M. Mihaylova et al.   CELL

Diagnosis and Classification of Diabetes Mellitus

(2011)   DIABETES CARE

Applications of post-translational modifications of FoxO family proteins in biological functions

(2011) Ying Zhao et al.   Journal of Molecular Cell Biology

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

(2010) Abishek Iyer et al.   BRITISH JOURNAL OF PHARMACOLOGY

HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive Rats

(2010) Jeffrey P. Cardinale et al.   HYPERTENSION

Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance

(2010) Alessia Peserico et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

FoxO1 and hepatic lipid metabolism

(2009) Janet D Sparks et al.   CURRENT OPINION IN LIPIDOLOGY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

O-glycosylation of FoxO1 increases its transcriptional activity towards the glucose 6-phosphatase gene

(2008) MeiShiue Kuo et al.   FEBS LETTERS

FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice

(2008) Adama Kamagate et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigallocatechin gallate (EGCG) attenuates high glucose-induced insulin signaling blockade in human hepG2 hepatoma cells

(2008) Chih-Li Lin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The FoxO code

(2008) D R Calnan et al.   ONCOGENE

Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification

(2008) Michael M. Brent et al.   STRUCTURE