Diisopropylamine Dichloroacetate, a Novel Pyruvate Dehydrogenase Kinase 4 Inhibitor, as a Potential Therapeutic Agent for Metabolic Disorders and Multiorgan Failure in Severe Influenza

IL-1β, RAGE and FABP4: targeting the dynamic trio in metabolic inflammation and related pathologies

(2013) Aimalie L Hardaway et al.   Future Medicinal Chemistry

Diabetic Ketoacidosis Elicits Systemic Inflammation Associated with Cerebrovascular Endothelial Cell Dysfunction

(2013) Taylor E. Close et al.   MICROCIRCULATION

Blood Lactate/ATP Ratio, as an Alarm Index and Real-Time Biomarker in Critical Illness

(2013) Junji Chida et al.   PLoS One

Regulation of energy metabolism by long-chain fatty acids

(2013) Manabu T. Nakamura et al.   PROGRESS IN LIPID RESEARCH

PPARγAgonists in Adaptive Immunity: What Do Immune Disorders and Their Models Have to Tell Us?

(2013) Laurindo Ferreira da Rocha Junior et al.   PPAR Research

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology

(2013) Gopinath Sutendra et al.   Frontiers in Oncology

An efficient extraction method for quantitation of adenosine triphosphate in mammalian tissues and cells

(2012) Junji Chida et al.   ANALYTICA CHIMICA ACTA

Mitochondrial-mediated antiviral immunity

(2012) Takumi Koshiba   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Alpha 1 Anti-Trypsin: One Protein, Many Functions

(2012) J. M. Hunt et al.   CURRENT MOLECULAR MEDICINE

Metformin Inhibits Growth Hormone-Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner

(2012) Y. D. Kim et al.   DIABETES

Activity-based kinase profiling of approved tyrosine kinase inhibitors

(2012) Daisuke Kitagawa et al.   GENES TO CELLS

Epidemiological Characteristics and Underlying Risk Factors for Mortality during the Autumn 2009 Pandemic Wave in Mexico

(2012) Gerardo Chowell et al.   PLoS One

Transcriptional Regulation of Pyruvate Dehydrogenase Kinase

(2012) Ji Yun Jeong et al.   Diabetes & Metabolism Journal

Role of host cellular proteases in the pathogenesis of influenza and influenza-induced multiple organ failure

(2011) Hiroshi Kido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Bezafibrate upregulates carnitine palmitoyltransferase II expression and promotes mitochondrial energy crisis dissipation in fibroblasts of patients with influenza-associated encephalopathy

(2011) Min Yao et al.   MOLECULAR GENETICS AND METABOLISM

Original Article: Peroxisome proliferator-activated receptor and AMP-activated protein kinase agonists protect against lethal influenza virus challenge in mice

(2010) Carson E. Moseley et al.   Influenza and Other Respiratory Viruses

Influenza Virus–Cytokine‐Protease Cycle in the Pathogenesis of Vascular Hyperpermeability in Severe Influenza

(2010) Siye Wang et al.   JOURNAL OF INFECTIOUS DISEASES

Induction of PDK4 in the heart muscle of JVS mice, an animal model of systemic carnitine deficiency, does not appear to reduce glucose utilization by the heart

(2010) Miharu Ushikai et al.   MOLECULAR GENETICS AND METABOLISM

Inflammatory cytokines in vascular dysfunction and vascular disease

(2009) Alexander H. Sprague et al.   BIOCHEMICAL PHARMACOLOGY

Adiponectin decreases pyruvate dehydrogenase kinase 4 gene expression in obese- and diabetic-derived myotubes

(2009) A. J. McAinch et al.   DIABETES OBESITY & METABOLISM

Confronting the next influenza pandemic with anti-inflammatory and immunomodulatory agents: why they are needed and how they might work

(2009) David S. Fedson   Influenza and Other Respiratory Viruses

TNF-induced mitochondrial damage: a link between mitochondrial complex I activity and left ventricular dysfunction

(2008) Nithya Mariappan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thermal instability of compound variants of carnitine palmitoyltransferase II and impaired mitochondrial fuel utilization in influenza-associated encephalopathy

(2008) Dengbing Yao et al.   HUMAN MUTATION