Pharmacological (or Synthetic) and Nutritional Agonists of PPAR-γ as Candidates for Cytokine Storm Modulation in COVID-19 Disease

Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID‐19) implicate special control measures

(2020) Yixuan Wang et al.   JOURNAL OF MEDICAL VIROLOGY

Pulmonary pathology of early phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer

(2020) Sufang Tian et al.   Journal of Thoracic Oncology

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

(2020) Canrong Wu et al.   Acta Pharmaceutica Sinica B

Different Drugs Effect on Mesenchymal Stem Cells Isolated From Abdominal Aortic Aneurysm

(2020) Rodolfo Pini et al.   ANNALS OF VASCULAR SURGERY

Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence

(2019) Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cytokine release syndrome

(2018) Alexander Shimabukuro-Vornhagen et al.   Journal for ImmunoTherapy of Cancer

PPARγ induces the gene expression of integrin ανβ5 to promote macrophage M2 polarization

(2018) Qinyu Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PubChem 2019 update: improved access to chemical data

(2018) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm

(2017) Carmen Ciavarella et al.   Stem Cell Research & Therapy

Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions

(2016) Francesco Maione et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fatty acids, eicosanoids and PPAR gamma

(2016) Rachel Marion-Letellier et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Curcumin, Inflammation, and Chronic Diseases: How Are They Linked?

(2015) Yan He et al.   MOLECULES

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

(2014) Limei Wang et al.   BIOCHEMICAL PHARMACOLOGY

p53 Degradation by a Coronavirus Papain-like Protease Suppresses Type I Interferon Signaling

(2014) Lin Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum species

(2014) Seungill Kim et al.   NATURE GENETICS

Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review

(2014) Bogna Grygiel-Górniak   Nutrition Journal

SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex

(2014) Xiaojuan Chen et al.   Protein & Cell

The Bioactivity and Toxicological Actions of Carvacrol

(2013) Zacharias E. Suntres et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Evaluation of Food-derived Functional Ingredients According to Activation of PPAR and Suppression of COX-2 Expression

(2013) Rieko NAKATA et al.   FOOD SCIENCE AND TECHNOLOGY RESEARCH

Peroxisome Proliferator-Activated Receptor Targets for the Treatment of Metabolic Diseases

(2013) Francisco A. Monsalve et al.   MEDIATORS OF INFLAMMATION

n-3 Fatty acids, inflammation and immunity: new mechanisms to explain old actions

(2013) Philip C. Calder   PROCEEDINGS OF THE NUTRITION SOCIETY

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

PPARγ is an E3 ligase that induces the degradation of NFκB/p65

(2012) Yongzhong Hou et al.   Nature Communications

Activation of PPARγ and δ by dietary punicic acid ameliorates intestinal inflammation in mice

(2011) Josep Bassaganya-Riera et al.   BRITISH JOURNAL OF NUTRITION

Dietary factors and low-grade inflammation in relation to overweight and obesity

(2011) Philip C. Calder et al.   BRITISH JOURNAL OF NUTRITION

Immunomodulatory therapy for severe influenza

(2011) Ilyse Darwish et al.   Expert Review of Anti-Infective Therapy

Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells

(2011) Maria Antonietta Ajmone-Cat et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Host response to influenza virus: protection versus immunopathology

(2010) JSM Peiris et al.   CURRENT OPINION IN IMMUNOLOGY

Original Article: Peroxisome proliferator-activated receptor and AMP-activated protein kinase agonists protect against lethal influenza virus challenge in mice

(2010) Carson E. Moseley et al.   Influenza and Other Respiratory Viruses

Fruit and vegetable consumption and proinflammatory gene expression from peripheral blood mononuclear cells in young adults: a translational study

(2010) Helen Hermana M Hermsdorff et al.   Nutrition & Metabolism

PPAR-γ Activation As an Anti-inflammatory Therapy for Respiratory Virus Infections

(2010) Josep Bassaganya-Riera et al.   VIRAL IMMUNOLOGY

Coactivators in PPAR-Regulated Gene Expression

(2010) Navin Viswakarma et al.   PPAR Research

Carvacrol, a component of thyme oil, activates PPARα and γ and suppresses COX-2 expression

(2009) Mariko Hotta et al.   JOURNAL OF LIPID RESEARCH

Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components

(2009) Harry Martin   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection

(2009) J. R. Aldridge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Pioglitazone versus Rosiglitazone: Effects on Lipids, Lipoproteins, and Apolipoproteins in Head-to-Head Randomized Clinical Studies

(2008) Mark A. Deeg et al.   PPAR Research