IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH Oxidase-mediated airway antiviral response

Dual Role of NOX2 in Respiratory Syncytial Virus- and Sendai Virus-Induced Activation of NF- B in Airway Epithelial Cells

(2014) K. Fink et al.   JOURNAL OF IMMUNOLOGY

Enhancement of Respiratory Mucosal Antiviral Defenses by the Oxidation of Iodide

(2011) Anthony J. Fischer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Dual Oxidase 2 is Essential for the Toll-Like Receptor 5-Mediated Inflammatory Response in Airway Mucosa

(2011) Jung-Hee Joo et al.   ANTIOXIDANTS & REDOX SIGNALING

The Airway Epithelium: Soldier in the Fight against Respiratory Viruses

(2011) M. Vareille et al.   CLINICAL MICROBIOLOGY REVIEWS

Pseudomonas aeruginosa Suppresses Interferon Response to Rhinovirus Infection in Cystic Fibrosis but Not in Normal Bronchial Epithelial Cells

(2011) Sangbrita S. Chattoraj et al.   INFECTION AND IMMUNITY

Dual Oxidase 1 Induced by Th2 Cytokines Promotes STAT6 Phosphorylation via Oxidative Inactivation of Protein Tyrosine Phosphatase 1B in Human Epidermal Keratinocytes

(2011) S. Hirakawa et al.   JOURNAL OF IMMUNOLOGY

Evaluation of the Calu-3 cell line as a model of in vitro respiratory syncytial virus infection

(2011) Jennifer L. Harcourt et al.   JOURNAL OF VIROLOGICAL METHODS

Rhinovirus-Induced Barrier Dysfunction in Polarized Airway Epithelial Cells Is Mediated by NADPH Oxidase 1

(2011) A. T. Comstock et al.   JOURNAL OF VIROLOGY

STAT2 Mediates Innate Immunity to Dengue Virus in the Absence of STAT1 via the Type I Interferon Receptor

(2011) Stuart T. Perry et al.   PLoS Pathogens

All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium

(2010) Angela Lee Linderholm et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Increased Cytokine Response of Rhinovirus-infected Airway Epithelial Cells in Chronic Obstructive Pulmonary Disease

(2010) Dina Schneider et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IFNγ mediates DUOX2 expression via a STAT-independent signaling pathway

(2010) Thomas Hill et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New developments in the induction and antiviral effectors of type I interferon

(2010) Su-Yang Liu et al.   CURRENT OPINION IN IMMUNOLOGY

Viral tricks to grid-lock the type I interferon system

(2010) Gijs A Versteeg et al.   CURRENT OPINION IN MICROBIOLOGY

Double-Stranded RNA Induces Shedding of the 34-kDa Soluble TNFR1 from Human Airway Epithelial Cells via TLR3-TRIF-RIP1-Dependent Signaling: Roles for Dual Oxidase 2- and Caspase-Dependent Pathways

(2010) M. Yu et al.   JOURNAL OF IMMUNOLOGY

Respiratory Syncytial Virus-Mediated NF- B p65 Phosphorylation at Serine 536 Is Dependent on RIG-I, TRAF6, and IKK 

(2010) F. Yoboua et al.   JOURNAL OF VIROLOGY

Delimitation and functional characterization of the bidirectional THOX–DUOXA promoter regions in thyrocytes

(2010) Christiane Christophe-Hobertus et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling

(2010) J. Kwon et al.   Science Signaling

Dual oxidase in mucosal immunity and host–microbe homeostasis

(2010) Yun Soo Bae et al.   TRENDS IN IMMUNOLOGY

Mechanisms and Function of DUOX in Epithelia of the Lung

(2009) Horst Fischer   ANTIOXIDANTS & REDOX SIGNALING

IFR-9/STAT2 Functional Interaction Drives Retinoic Acid-Induced Gene G Expression Independently of STAT1

(2009) Y.-J. Lou et al.   CANCER RESEARCH

Oxidative epithelial host defense is regulated by infectious and inflammatory stimuli

(2009) Monica Valencia Gattas et al.   FREE RADICAL BIOLOGY AND MEDICINE

ATP-mediated Activation of the NADPH Oxidase DUOX1 Mediates Airway Epithelial Responses to Bacterial Stimuli

(2009) Agnes W. Boots et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Dual Oxidases Duox1 and Duox2

(2009) Sabrina Rigutto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Respiratory Syncytial Virus Nonstructural Proteins Decrease Levels of Multiple Members of the Cellular Interferon Pathways

(2009) S. Swedan et al.   JOURNAL OF VIROLOGY

Coordination of multiple dual oxidase–regulatory pathways in responses to commensal and infectious microbes in drosophila gut

(2009) Eun-Mi Ha et al.   NATURE IMMUNOLOGY

Silencing of DUOX NADPH Oxidases by Promoter Hypermethylation in Lung Cancer

(2008) S. Luxen et al.   CANCER RESEARCH

The role of respiratory viruses in cystic fibrosis

(2008) Dennis Wat et al.   Journal of Cystic Fibrosis

The Addition of Tumor Necrosis Factor plus Beta Interferon Induces a Novel Synergistic Antiviral State against Poxviruses in Primary Human Fibroblasts

(2008) E. Bartee et al.   JOURNAL OF VIROLOGY

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

(2008) Anna Yarilina et al.   NATURE IMMUNOLOGY