Comparing proteins and nucleic acids for next-generation biomolecular engineering

Structural Transformation of Wireframe DNA Origami via DNA Polymerase Assisted Gap-Filling

(2018) Nayan P. Agarwal et al.   ACS Nano

Evolution of sequence-defined highly functionalized nucleic acid polymers

(2018) Zhen Chen et al.   Nature Chemistry

DNA scaffolds support stable and uniform peptide nanopores

(2018) Evan Spruijt et al.   Nature Nanotechnology

Membrane sculpting by curved DNA origami scaffolds

(2018) Henri G. Franquelim et al.   Nature Communications

The making of bispecific antibodies

(2017) Ulrich Brinkmann et al.   mAbs

Expanding and reprogramming the genetic code

(2017) Jason W. Chin   NATURE

Evolution of a designed protein assembly encapsulating its own RNA genome

(2017) Gabriel L. Butterfield et al.   NATURE

Biotechnological mass production of DNA origami

(2017) Florian Praetorius et al.   NATURE

Fractal assembly of micrometre-scale DNA origami arrays with arbitrary patterns

(2017) Grigory Tikhomirov et al.   NATURE

Gigadalton-scale shape-programmable DNA assemblies

(2017) Klaus F. Wagenbauer et al.   NATURE

Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm

(2017) Matthew J Lee et al.   Nature Chemical Biology

Enantioselective, intermolecular benzylic C–H amination catalysed by an engineered iron-haem enzyme

(2017) Christopher K. Prier et al.   Nature Chemistry

Placing and shaping liposomes with reconfigurable DNA nanocages

(2017) Zhao Zhang et al.   Nature Chemistry

Assembly of a biocompatible triazole-linked gene by one-pot click-DNA ligation

(2017) Mikiembo Kukwikila et al.   Nature Chemistry

DNA-imprinted polymer nanoparticles with monodispersity and prescribed DNA-strand patterns

(2017) Tuan Trinh et al.   Nature Chemistry

DNA nanotechnology: Bringing lipid bilayers into shape

(2017) Stefan Howorka   Nature Chemistry

Engineering nucleic acid structures for programmable molecular circuitry and intracellular biocomputation

(2017) Jiang Li et al.   Nature Chemistry

Building membrane nanopores

(2017) Stefan Howorka   Nature Nanotechnology

Tragedy, Perseverance, and Chance — The Story of CAR-T Therapy

(2017) Lisa Rosenbaum   NEW ENGLAND JOURNAL OF MEDICINE

DNA-assisted oligomerization of pore-forming toxin monomers into precisely-controlled protein channels

(2017) Anja Henning-Knechtel et al.   NUCLEIC ACIDS RESEARCH

Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis

(2017) Stephan C. Hammer et al.   SCIENCE

Comprehensive computational design of ordered peptide macrocycles

(2017) Parisa Hosseinzadeh et al.   SCIENCE

Global analysis of protein folding using massively parallel design, synthesis, and testing

(2017) Gabriel J. Rocklin et al.   SCIENCE

Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes

(2017) Florian Praetorius et al.   SCIENCE

Assembly principles and structure of a 6.5-MDa bacterial microcompartment shell

(2017) Markus Sutter et al.   SCIENCE

The Growing and Glowing Toolbox of Fluorescent and Photoactive Proteins

(2017) Erik A. Rodriguez et al.   TRENDS IN BIOCHEMICAL SCIENCES

DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis

(2017) Nirit Mor-Vaknin et al.   Nature Communications

Enzyme catalysed Pictet-Spengler formation of chiral 1,1’-disubstituted- and spiro-tetrahydroisoquinolines

(2017) Benjamin R. Lichman et al.   Nature Communications

Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange

(2017) Sandrine Guillard et al.   Nature Communications

Control of enzyme reactions by a reconfigurable DNA nanovault

(2017) Guido Grossi et al.   Nature Communications

A reverse transcriptase ribozyme

(2017) Biswajit Samanta et al.   eLife

DNA nanotechnology

(2017) Nadrian C. Seeman et al.   Nature Reviews Materials

Advancements in Aptamer Discovery Technologies

(2016) Michael R. Gotrik et al.   ACCOUNTS OF CHEMICAL RESEARCH

Selection platforms for directed evolution in synthetic biology

(2016) P. A. G. Tizei et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Synthesis of chemically modified DNA

(2016) A. Shivalingam et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Cellular processing and destinies of artificial DNA nanostructures

(2016) Di Sheng Lee et al.   CHEMICAL SOCIETY REVIEWS

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

(2016) Hong-Min Meng et al.   CHEMICAL SOCIETY REVIEWS

Engineered transmembrane pores

(2016) Mariam Ayub et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The expanding world of DNA and RNA

(2016) Tingjian Chen et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A Programmable DNA Origami Platform to Organize SNAREs for Membrane Fusion

(2016) Weiming Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembly of an α-Helical Peptide into a Crystalline Two-Dimensional Nanoporous Framework

(2016) Elizabeth L. Magnotti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembly of coherently dynamic, auxetic, two-dimensional protein crystals

(2016) Yuta Suzuki et al.   NATURE

Crystal structure of a DNA catalyst

(2016) Almudena Ponce-Salvatierra et al.   NATURE

Engineering and mapping nanocavity emission via precision placement of DNA origami

(2016) Ashwin Gopinath et al.   NATURE

Directed evolution of artificial metalloenzymes for in vivo metathesis

(2016) Markus Jeschek et al.   NATURE

The coming of age of de novo protein design

(2016) Po-Ssu Huang et al.   NATURE

A split horseradish peroxidase for the detection of intercellular protein–protein interactions and sensitive visualization of synapses

(2016) Jeffrey D Martell et al.   NATURE BIOTECHNOLOGY

Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models

(2016) Sheel C. Dodani et al.   Nature Chemistry

Recent advances in the construction of antibody–drug conjugates

(2016) Vijay Chudasama et al.   Nature Chemistry

An autonomous molecular assembler for programmable chemical synthesis

(2016) Wenjing Meng et al.   Nature Chemistry

Installing hydrolytic activity into a completely de novo protein framework

(2016) Antony J. Burton et al.   Nature Chemistry

Transfer of molecular recognition information from DNA nanostructures to gold nanoparticles

(2016) Thomas G. W. Edwardson et al.   Nature Chemistry

Self-assembly of size-controlled liposomes on DNA nanotemplates

(2016) Yang Yang et al.   Nature Chemistry

G-quadruplex structures mark human regulatory chromatin

(2016) Robert Hänsel-Hertsch et al.   NATURE GENETICS

Enzymatic reactions in confined environments

(2016) Andreas Küchler et al.   Nature Nanotechnology

A biomimetic DNA-based channel for the ligand-controlled transport of charged molecular cargo across a biological membrane

(2016) Jonathan R. Burns et al.   Nature Nanotechnology

Digitally encoded DNA nanostructures for multiplexed, single-molecule protein sensing with nanopores

(2016) Nicholas A. W. Bell et al.   Nature Nanotechnology

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Structural basis for specific inhibition of Autotaxin by a DNA aptamer

(2016) Kazuki Kato et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proteome- pI : proteome isoelectric point database

(2016) Lukasz P. Kozlowski   NUCLEIC ACIDS RESEARCH

Amplification of RNA by an RNA polymerase ribozyme

(2016) David P. Horning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo aspects of protein folding and quality control

(2016) D. Balchin et al.   SCIENCE

Diamond family of nanoparticle superlattices

(2016) W. Liu et al.   SCIENCE

Designer nanoscale DNA assemblies programmed from the top down

(2016) R. Veneziano et al.   SCIENCE

Synthetic evolutionary origin of a proofreading reverse transcriptase

(2016) J. W. Ellefson et al.   SCIENCE

Changing of the guard

(2016) S. Howorka   SCIENCE

Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes

(2016) Scott K. Silverman   TRENDS IN BIOCHEMICAL SCIENCES

Structural basis for specific inhibition of Autotaxin by a DNA aptamer

(2016) Kazuki Kato et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane-Assisted Growth of DNA Origami Nanostructure Arrays

(2015) Samet Kocabey et al.   ACS Nano

Expanding the Enzyme Universe: Accessing Non-Natural Reactions by Mechanism-Guided Directed Evolution

(2015) Hans Renata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiscale Origami Structures as Interface for Cells

(2015) Alessandro Angelin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amphipathic DNA Origami Nanoparticles to Scaffold and Deform Lipid Membrane Vesicles

(2015) Aleksander Czogalla et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in Antibody Design

(2015) Kathryn E. Tiller et al.   Annual Review of Biomedical Engineering

Designed Ankyrin Repeat Proteins (DARPins): Binding Proteins for Research, Diagnostics, and Therapy

(2015) Andreas Plückthun   Annual Review of Pharmacology and Toxicology

Directed Evolution of Enzymes for Industrial Biocatalysis

(2015) Joanne L. Porter et al.   CHEMBIOCHEM

A modular DNA origami-based enzyme cascade nanoreactor

(2015) Veikko Linko et al.   CHEMICAL COMMUNICATIONS

Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently

(2015) Andrew Currin et al.   CHEMICAL SOCIETY REVIEWS

Improving and repurposing biocatalysts via directed evolution

(2015) Carl A Denard et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

DNA-based hybrid catalysis

(2015) Ana Rioz-Martínez et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

De novo protein design: how do we expand into the universe of possible protein structures?

(2015) Derek N Woolfson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Enzyme engineering in biomimetic compartments

(2015) Pierre-Yves Colin et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Bispecific antibodies

(2015) Roland E. Kontermann et al.   DRUG DISCOVERY TODAY

Modular Design of Self-Assembling Peptide-Based Nanotubes

(2015) Natasha C. Burgess et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA rendering of polyhedral meshes at the nanoscale

(2015) Erik Benson et al.   NATURE

Guiding the folding pathway of DNA origami

(2015) Katherine E. Dunn et al.   NATURE

Opposing effects of folding and assembly chaperones on evolvability of Rubisco

(2015) Paulo Durão et al.   Nature Chemical Biology

Routing of individual polymers in designed patterns

(2015) Jakob Bach Knudsen et al.   Nature Nanotechnology

Complex wireframe DNA origami nanostructures with multi-arm junction vertices

(2015) Fei Zhang et al.   Nature Nanotechnology

A stochastic DNA walker that traverses a microparticle surface

(2015) C. Jung et al.   Nature Nanotechnology

Designing DNA nanodevices for compatibility with the immune system of higher organisms

(2015) Sunaina Surana et al.   Nature Nanotechnology

DNA nanotechnology from the test tube to the cell

(2015) Yuan-Jyue Chen et al.   Nature Nanotechnology

Methods for the directed evolution of proteins

(2015) Michael S. Packer et al.   NATURE REVIEWS GENETICS

Building endocytic pits without clathrin

(2015) Ludger Johannes et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Control of repeat-protein curvature by computational protein design

(2015) Keunwan Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamic DNA devices and assemblies formed by shape-complementary, non-base pairing 3D components

(2015) T. Gerling et al.   SCIENCE

Programmable materials and the nature of the DNA bond

(2015) M. R. Jones et al.   SCIENCE

A Naturally Occurring Repeat Protein with High Internal Sequence Identity Defines a New Class of TPR-like Proteins

(2015) Jacob D. Marold et al.   STRUCTURE

Membrane transporter engineering in industrial biotechnology and whole cell biocatalysis

(2015) Douglas B. Kell et al.   TRENDS IN BIOTECHNOLOGY

A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy

(2015) Antoine Maruani et al.   Nature Communications

Control of repeat-protein curvature by computational protein design

(2015) Keunwan Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Virus-Inspired Membrane Encapsulation of DNA Nanostructures To Achieve In Vivo Stability

(2014) Steven D. Perrault et al.   ACS Nano

DNA–Cholesterol Barges as Programmable Membrane-Exploring Agents

(2014) Alexander Johnson-Buck et al.   ACS Nano

Hydrophobic Actuation of a DNA Origami Bilayer Structure

(2014) Jonathan List et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies

(2014) Fernando Garces et al.   CELL

Molecular tools for the construction of peptide-based materials

(2014) B. E. I. Ramakers et al.   CHEMICAL SOCIETY REVIEWS

Self-assembled plasmonic nanostructures

(2014) Anna Klinkova et al.   CHEMICAL SOCIETY REVIEWS

Advances in the directed evolution of proteins

(2014) Michael D Lane et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Computational tools for designing and engineering enzymes

(2014) Jiri Damborsky et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Computer aided enzyme design and catalytic concepts

(2014) Maria P Frushicheva et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Design of proteins from smaller fragments—learning from evolution

(2014) Birte Höcker   CURRENT OPINION IN STRUCTURAL BIOLOGY

Engineered proteins with desired specificity: DARPins, other alternative scaffolds and bispecific IgGs

(2014) Christian Jost et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure of a type IV secretion system

(2014) Harry H. Low et al.   NATURE

Negative selection and stringency modulation in phage-assisted continuous evolution

(2014) Jacob C Carlson et al.   Nature Chemical Biology

Engineering the product profile of a polysialyltransferase

(2014) Timothy G Keys et al.   Nature Chemical Biology

Evolutionary relationship of two ancient protein superfolds

(2014) José Arcadio Farías-Rico et al.   Nature Chemical Biology

Evolution of enzyme catalysts caged in biomimetic gel-shell beads

(2014) Martin Fischlechner et al.   Nature Chemistry

Structure of a designed protein cage that self-assembles into a highly porous cube

(2014) Yen-Ting Lai et al.   Nature Chemistry

Universal computing by DNA origami robots in a living animal

(2014) Yaniv Amir et al.   Nature Nanotechnology

Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm

(2014) Jinglin Fu et al.   Nature Nanotechnology

Engineering adeno-associated viruses for clinical gene therapy

(2014) Melissa A. Kotterman et al.   NATURE REVIEWS GENETICS

Biogenesis and functions of bacterial S-layers

(2014) Robert P. Fagan et al.   NATURE REVIEWS MICROBIOLOGY

Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase

(2014) N. Preiswerk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A single-stranded architecture for cotranscriptional folding of RNA nanostructures

(2014) C. Geary et al.   SCIENCE

Polyhedra Self-Assembled from DNA Tripods and Characterized with 3D DNA-PAINT

(2014) R. Iinuma et al.   SCIENCE

Casting inorganic structures with DNA molds

(2014) W. Sun et al.   SCIENCE

Towards XNA nanotechnology: new materials from synthetic genetic polymers

(2014) Vitor B. Pinheiro et al.   TRENDS IN BIOTECHNOLOGY

Selective chemical protein modification

(2014) Christopher D. Spicer et al.   Nature Communications

Artificial Genetic Sets Composed of Size-Expanded Base Pairs

(2013) Malte Winnacker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanobodies: Natural Single-Domain Antibodies

(2013) Serge Muyldermans   Annual Review of Biochemistry

Design of Protein Catalysts

(2013) Donald Hilvert   Annual Review of Biochemistry

Change, exchange, and rearrange: protein engineering for the biotechnological production of fuels, pharmaceuticals, and other chemicals

(2013) Michael A Fisher et al.   CURRENT OPINION IN BIOTECHNOLOGY

Pathway and protein engineering approaches to produce novel and commodity small molecules

(2013) Namita Bhan et al.   CURRENT OPINION IN BIOTECHNOLOGY

Self-assembled two-dimensional protein arrays in bionanotechnology: from S-layers to designed lattices

(2013) François Baneyx et al.   CURRENT OPINION IN BIOTECHNOLOGY

De novo enzymes by computational design

(2013) Hajo Kries et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Strategies for the discovery and engineering of enzymes for biocatalysis

(2013) Timo Davids et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Rational Design of Helical Nanotubes from Self-Assembly of Coiled-Coil Lock Washers

(2013) Chunfu Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembled DNA Nanopores That Span Lipid Bilayers

(2013) Jonathan R. Burns et al.   NANO LETTERS

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies

(2013) Masaru Kanekiyo et al.   NATURE

Precision is essential for efficient catalysis in an evolved Kemp eliminase

(2013) Rebecca Blomberg et al.   NATURE

Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies

(2013) Christoph Spiess et al.   NATURE BIOTECHNOLOGY

Evolution of a designed retro-aldolase leads to complete active site remodeling

(2013) Lars Giger et al.   Nature Chemical Biology

Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments

(2013) Helena Gradišar et al.   Nature Chemical Biology

Site-specific positioning of dendritic alkyl chains on DNA cages enables their geometry-dependent self-assembly

(2013) Thomas G. W. Edwardson et al.   Nature Chemistry

Transport and self-organization across different length scales powered by motor proteins and programmed by DNA

(2013) Adam J. M. Wollman et al.   Nature Nanotechnology

Two DNA nanomachines map pH changes along intersecting endocytic pathways inside the same cell

(2013) Souvik Modi et al.   Nature Nanotechnology

Antibody–drug conjugates

(2013) Rachel S. Zolot et al.   NATURE REVIEWS DRUG DISCOVERY

Engineering of TEV protease variants by yeast ER sequestration screening (YESS) of combinatorial libraries

(2013) L. Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-Assembling Cages from Coiled-Coil Peptide Modules

(2013) J. M. Fletcher et al.   SCIENCE

Protein folding and de novo protein design for biotechnological applications

(2013) George A. Khoury et al.   TRENDS IN BIOTECHNOLOGY

DNA-based self-assembly of chiral plasmonic nanostructures with tailored optical response

(2012) Anton Kuzyk et al.   NATURE

SbsB structure and lattice reconstruction unveil Ca2+ triggered S-layer assembly

(2012) Ekaterina Baranova et al.   NATURE

Complex shapes self-assembled from single-stranded DNA tiles

(2012) Bryan Wei et al.   NATURE

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Natural strategies for the spatial optimization of metabolism in synthetic biology

(2012) Christina M Agapakis et al.   Nature Chemical Biology

Structure and dynamics of a primordial catalytic fold generated by in vitro evolution

(2012) Fa-An Chao et al.   Nature Chemical Biology

Metal-directed, chemically tunable assembly of one-, two- and three-dimensional crystalline protein arrays

(2012) Jeffrey D. Brodin et al.   Nature Chemistry

A DNA-based molecular motor that can navigate a network of tracks

(2012) Shelley F. J. Wickham et al.   Nature Nanotechnology

Engineering a model protein cavity to catalyze the Kemp elimination

(2012) M. Merski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy

(2012) N. P. King et al.   SCIENCE

Synthetic Lipid Membrane Channels Formed by Designed DNA Nanostructures

(2012) M. Langecker et al.   SCIENCE

Three-Dimensional Structures Self-Assembled from DNA Bricks

(2012) Y. Ke et al.   SCIENCE

Fluorescence Enhancement at Docking Sites of DNA-Directed Self-Assembled Nanoantennas

(2012) G. P. Acuna et al.   SCIENCE

Tug-of-War in Motor Protein Ensembles Revealed with a Programmable DNA Origami Scaffold

(2012) N. D. Derr et al.   SCIENCE

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

Nature Versus Nurture: Developing Enzymes That Function Under Extreme Conditions

(2012) Michael J. Liszka et al.   Annual Review of Chemical and Biomolecular Engineering

DNA Origami: The Art of Folding DNA

(2011) Barbara Saccà et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conformational changes of non-B DNA

(2011) Jungkweon Choi et al.   CHEMICAL SOCIETY REVIEWS

DNA origami: a quantum leap for self-assembly of complex structures

(2011) Thomas Tørring et al.   CHEMICAL SOCIETY REVIEWS

S-layer fusion proteins—construction principles and applications

(2011) Nicola Ilk et al.   CURRENT OPINION IN BIOTECHNOLOGY

DARPins and other repeat protein scaffolds: advances in engineering and applications

(2011) Ykelien L Boersma et al.   CURRENT OPINION IN BIOTECHNOLOGY

Neutralization ofClostridium difficileToxin A with Single-domain Antibodies Targeting the Cell Receptor Binding Domain

(2011) Greg Hussack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Origami Nanopores

(2011) Nicholas A. W. Bell et al.   NANO LETTERS

Programmable molecular recognition based on the geometry of DNA nanostructures

(2011) Sungwook Woo et al.   Nature Chemistry

A primer to scaffolded DNA origami

(2011) Carlos Ernesto Castro et al.   NATURE METHODS

Building plasmonic nanostructures with DNA

(2011) Shawn J. Tan et al.   Nature Nanotechnology

Challenges and opportunities for structural DNA nanotechnology

(2011) Andre V. Pinheiro et al.   Nature Nanotechnology

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Design of a switchable eliminase

(2011) I. V. Korendovych et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A general strategy for the evolution of bond-forming enzymes using yeast display

(2011) I. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organization of Intracellular Reactions with Rationally Designed RNA Assemblies

(2011) C. J. Delebecque et al.   SCIENCE

DNA Origami with Complex Curvatures in Three-Dimensional Space

(2011) D. Han et al.   SCIENCE

Orthogonal Protein Decoration of DNA Origami

(2010) Barbara Saccà et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanomaterials Based on DNA

(2010) Nadrian C. Seeman   Annual Review of Biochemistry

Bacterial Microcompartment Organelles: Protein Shell Structure and Evolution

(2010) Todd O. Yeates et al.   Annual Review of Biophysics

Bacterial Microcompartments

(2010) Cheryl A. Kerfeld et al.   Annual Review of Microbiology

More than just bare scaffolds: towards multi-component and decorated fibrous biomaterials

(2010) Derek N. Woolfson et al.   CHEMICAL SOCIETY REVIEWS

Design, Production and Molecular Structure of a New Family of Artificial Alpha-helicoidal Repeat Proteins (αRep) Based on Thermostable HEAT-like Repeats

(2010) Agathe Urvoas et al.   JOURNAL OF MOLECULAR BIOLOGY

Single-Molecule Kinetics and Super-Resolution Microscopy by Fluorescence Imaging of Transient Binding on DNA Origami

(2010) Ralf Jungmann et al.   NANO LETTERS

Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

(2010) Eric J. Steen et al.   NATURE

Catalytic enantioselective syn hydration of enones in water using a DNA-based catalyst

(2010) Arnold J. Boersma et al.   Nature Chemistry

Biologically templated photocatalytic nanostructures for sustained light-driven water oxidation

(2010) Yoon Sung Nam et al.   Nature Nanotechnology

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

Short N-terminal sequences package proteins into bacterial microcompartments

(2010) C. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Mechanisms of a Protein-Based Organelle in Escherichia coli

(2010) S. Tanaka et al.   SCIENCE

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

(2010) D. G. Gibson et al.   SCIENCE

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Design of functional metalloproteins

(2009) Yi Lu et al.   NATURE

Self-assembly of DNA into nanoscale three-dimensional shapes

(2009) Shawn M. Douglas et al.   NATURE

From molecular to macroscopic via the rational design of a self-assembled 3D DNA crystal

(2009) Jianping Zheng et al.   NATURE

Self-assembly of a nanoscale DNA box with a controllable lid

(2009) Ebbe S. Andersen et al.   NATURE

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Computer-aided design of functional protein interactions

(2009) Daniel J Mandell et al.   Nature Chemical Biology

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

Large-area spatially ordered arrays of gold nanoparticles directed by lithographically confined DNA origami

(2009) Albert M. Hung et al.   Nature Nanotechnology

A DNA nanomachine that maps spatial and temporal pH changes inside living cells

(2009) Souvik Modi et al.   Nature Nanotechnology

Enzyme cascades activated on topologically programmed DNA scaffolds

(2009) Ofer I. Wilner et al.   Nature Nanotechnology

Placement and orientation of individual DNA shapes on lithographically patterned surfaces

(2009) Ryan J. Kershner et al.   Nature Nanotechnology

Rapid prototyping of 3D DNA-origami shapes with caDNAno

(2009) Shawn M. Douglas et al.   NUCLEIC ACIDS RESEARCH

Folding DNA into Twisted and Curved Nanoscale Shapes

(2009) H. Dietz et al.   SCIENCE

A Bipedal DNA Brownian Motor with Coordinated Legs

(2009) Tosan Omabegho et al.   SCIENCE

Control of Self-Assembly of DNA Tubules Through Integration of Gold Nanoparticles

(2009) J. Sharma et al.   SCIENCE

Closed nanoconstructs assembled by step-by-step ss-DNA coupling assisted by phospholipid membranes

(2009) Francesca Baldelli Bombelli et al.   Soft Matter

Expressed Protein Ligation (EPL) in the Study of Signal Transduction, Ion Conduction, And Chromatin Biology

(2008) Robert R. Flavell et al.   ACCOUNTS OF CHEMICAL RESEARCH

Structural Basis of Membrane Invagination by F-BAR Domains

(2008) Adam Frost et al.   CELL

Kemp elimination catalysts by computational enzyme design

(2008) Daniela Röthlisberger et al.   NATURE

Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra

(2008) Yu He et al.   NATURE

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

(2008) Shota Atsumi et al.   NATURE

Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases

(2008) Paul E O'Maille et al.   Nature Chemical Biology

Self-assembled DNA nanostructures for distance-dependent multivalent ligand–protein binding

(2008) Sherri Rinker et al.   Nature Nanotechnology

The exploration of macrocycles for drug discovery — an underexploited structural class

(2008) Edward M. Driggers et al.   NATURE REVIEWS DRUG DISCOVERY

De Novo Computational Design of Retro-Aldol Enzymes

(2008) L. Jiang et al.   SCIENCE

Designed Protein-Protein Association

(2008) D. Grueninger et al.   SCIENCE

Assembling Materials with DNA as the Guide

(2008) F. A. Aldaye et al.   SCIENCE

Tumor Regression in Cancer Patients by Very Low Doses of a T Cell-Engaging Antibody

(2008) R. Bargou et al.   SCIENCE

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

(2008) D. G. Gibson et al.   SCIENCE