- Home
- Publications
- Publication Search
- Publication Details
Title
In vivo aspects of protein folding and quality control
Authors
Keywords
-
Journal
SCIENCE
Volume 353, Issue 6294, Pages aac4354-aac4354
Publisher
American Association for the Advancement of Science (AAAS)
Online
2016-07-01
DOI
10.1126/science.aac4354
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Allosteric Mechanisms in Chaperonin Machines
- (2016) Ranit Gruber et al. CHEMICAL REVIEWS
- A current pharmacologic agent versus the promise of next generation therapeutics to ameliorate protein misfolding and/or aggregation diseases
- (2016) Aleksandra Baranczak et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Trigger Factor Reduces the Force Exerted on the Nascent Chain by a Cotranslationally Folding Protein
- (2016) Ola B. Nilsson et al. JOURNAL OF MOLECULAR BIOLOGY
- From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations
- (2016) Gudio Veit et al. MOLECULAR BIOLOGY OF THE CELL
- The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model
- (2016) Vaishali Kakkar et al. MOLECULAR CELL
- Failure of RQC machinery causes protein aggregation and proteotoxic stress
- (2016) Young-Jun Choe et al. NATURE
- A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding
- (2016) Lisa D Cabrita et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ribosome-associated protein quality control
- (2016) Onn Brandman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Hsp70 biases the folding pathways of client proteins
- (2016) Ashok Sekhar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extended survival of misfolded G85R SOD1-linked ALS mice by transgenic expression of chaperone Hsp110
- (2016) Maria Nagy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The GroEL–GroES Chaperonin Machine: A Nano-Cage for Protein Folding
- (2016) Manajit Hayer-Hartl et al. TRENDS IN BIOCHEMICAL SCIENCES
- A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding
- (2016) Lisa D Cabrita et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ribosome-associated protein quality control
- (2016) Onn Brandman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Clarifying the Translational Pausing Landscape in Bacteria by Ribosome Profiling
- (2016) Fuad Mohammad et al. Cell Reports
- The Biology of Proteostasis in Aging and Disease
- (2015) Johnathan Labbadia et al. Annual Review of Biochemistry
- Targeting Hsp90/Hsp70-Based Protein Quality Control for Treatment of Adult Onset Neurodegenerative Diseases
- (2015) William B. Pratt et al. Annual Review of Pharmacology and Toxicology
- Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress
- (2015) Edward W.J. Wallace et al. CELL
- Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity
- (2015) Danny D. Nedialkova et al. CELL
- Widespread Proteome Remodeling and Aggregation in Aging C. elegans
- (2015) Dirk M. Walther et al. CELL
- Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders
- (2015) Nidhi Sahni et al. CELL
- Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection
- (2015) Shuhei Taguwa et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- Endocrine aspects of organelle stress — cell non-autonomous signaling of mitochondria and the ER
- (2015) Robert Schinzel et al. CURRENT OPINION IN CELL BIOLOGY
- Not4-dependent translational repression is important for cellular protein homeostasis in yeast
- (2015) S. Preissler et al. EMBO JOURNAL
- Structural, morphological, and functional diversity of amyloid oligomers
- (2015) Leonid Breydo et al. FEBS LETTERS
- Therapeutic targeting of autophagy in neurodegenerative and infectious diseases
- (2015) David C. Rubinsztein et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Reaction Cycle of Chaperonin GroEL via Symmetric “Football” Intermediate
- (2015) Hideki Taguchi JOURNAL OF MOLECULAR BIOLOGY
- Prolyl Isomerization and Its Catalysis in Protein Folding and Protein Function
- (2015) Philipp A.M. Schmidpeter et al. JOURNAL OF MOLECULAR BIOLOGY
- How Hsp70 Molecular Machines Interact with Their Substrates to Mediate Diverse Physiological Functions
- (2015) Eugenia M. Clerico et al. JOURNAL OF MOLECULAR BIOLOGY
- The Mechanism and Function of Group II Chaperonins
- (2015) Tom Lopez et al. JOURNAL OF MOLECULAR BIOLOGY
- GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
- (2015) Brian D. Freibaum et al. NATURE
- Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation
- (2015) Nadinath B. Nillegoda et al. NATURE
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Heterogeneous binding of the SH3 client protein to the DnaK molecular chaperone
- (2015) Jung Ho Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mapping the conformation of a client protein through the Hsp70 functional cycle
- (2015) Ashok Sekhar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structures of the Gβ-CCT and PhLP1–Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly
- (2015) Rebecca L. Plimpton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90
- (2015) Edgar E. Boczek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Substrate-binding domain conformational dynamics mediate Hsp70 allostery
- (2015) Anastasia Zhuravleva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The principle of antagonism ensures protein targeting specificity at the endoplasmic reticulum
- (2015) M. Gamerdinger et al. SCIENCE
- Operon structure and cotranslational subunit association direct protein assembly in bacteria
- (2015) Y.-W. Shieh et al. SCIENCE
- Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA
- (2015) A. C. Woerner et al. SCIENCE
- Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit
- (2015) I. Das et al. SCIENCE
- Translational tuning optimizes nascent protein folding in cells
- (2015) S. J. Kim et al. SCIENCE
- Cotranslational protein folding on the ribosome monitored in real time
- (2015) W. Holtkamp et al. SCIENCE
- Mutations in a translation initiation factor identify the target of a memory-enhancing compound
- (2015) Y. Sekine et al. SCIENCE
- Identification and characterization of essential genes in the human genome
- (2015) T. Wang et al. SCIENCE
- A Bipartite Interaction between Hsp70 and CHIP Regulates Ubiquitination of Chaperoned Client Proteins
- (2015) Huaqun Zhang et al. STRUCTURE
- Hsp90 interaction with clients
- (2015) G. Elif Karagöz et al. TRENDS IN BIOCHEMICAL SCIENCES
- Emerging Roles of Disordered Sequences in RNA-Binding Proteins
- (2015) Sara Calabretta et al. TRENDS IN BIOCHEMICAL SCIENCES
- Action of the Hsp70 chaperone system observed with single proteins
- (2015) João M. Nunes et al. Nature Communications
- Transient misfolding dominates multidomain protein folding
- (2015) Alessandro Borgia et al. Nature Communications
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Hsp70 Forms Antiparallel Dimers Stabilized by Post-translational Modifications to Position Clients for Transfer to Hsp90
- (2015) Nina Morgner et al. Cell Reports
- Cotranslational Protein Folding inside the Ribosome Exit Tunnel
- (2015) Ola B. Nilsson et al. Cell Reports
- Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic
- (2015) Aaron S Mendez et al. eLife
- Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response
- (2015) Carmela Sidrauski et al. eLife
- Glucocorticoid Receptor Function Regulated by Coordinated Action of the Hsp90 and Hsp70 Chaperone Cycles
- (2014) Elaine Kirschke et al. CELL
- GroEL/ES Chaperonin Modulates the Mechanism and Accelerates the Rate of TIM-Barrel Domain Folding
- (2014) Florian Georgescauld et al. CELL
- A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways
- (2014) Mikko Taipale et al. CELL
- The Structural Basis of Substrate Recognition by the Eukaryotic Chaperonin TRiC/CCT
- (2014) Lukasz A. Joachimiak et al. CELL
- Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action
- (2014) G. Elif Karagöz et al. CELL
- Small heat-shock proteins: important players in regulating cellular proteostasis
- (2014) Teresa M. Treweek et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Sorting out the trash: the spatial nature of eukaryotic protein quality control
- (2014) Emily M Sontag et al. CURRENT OPINION IN CELL BIOLOGY
- Aneuploidy: implications for protein homeostasis and disease
- (2014) A. B. Oromendia et al. Disease Models & Mechanisms
- The C-terminal Tails of the Bacterial Chaperonin GroEL Stimulate Protein Folding by Directly Altering the Conformation of a Substrate Protein
- (2014) Jeremy Weaver et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chaperones Rescue Luciferase Folding by Separating Its Domains
- (2014) Zackary N. Scholl et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Active Cage Mechanism of Chaperonin-Assisted Protein Folding Demonstrated at Single-Molecule Level
- (2014) Amit J. Gupta et al. JOURNAL OF MOLECULAR BIOLOGY
- Elucidating the Mechanism of Substrate Recognition by the Bacterial Hsp90 Molecular Chaperone
- (2014) Timothy O. Street et al. JOURNAL OF MOLECULAR BIOLOGY
- Energy landscapes of functional proteins are inherently risky
- (2014) Anne Gershenson et al. Nature Chemical Biology
- Structural basis for interaction of a cotranslational chaperone with the eukaryotic ribosome
- (2014) Yixiao Zhang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ER Stress-Induced eIF2-alpha Phosphorylation Underlies Sensitivity of Striatal Neurons to Pathogenic Huntingtin
- (2014) Julia Leitman et al. PLoS One
- Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain
- (2014) C. B. Cooley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Life-span extension by a metacaspase in the yeast Saccharomyces cerevisiae
- (2014) S. M. Hill et al. SCIENCE
- Structural Basis for Protein Antiaggregation Activity of the Trigger Factor Chaperone
- (2014) T. Saio et al. SCIENCE
- Proteostasis impairment in protein-misfolding and -aggregation diseases
- (2014) Mark S. Hipp et al. TRENDS IN CELL BIOLOGY
- A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease
- (2014) Marc Brehme et al. Cell Reports
- Hsp70 chaperones are non-equilibrium machines that achieve ultra-affinity by energy consumption
- (2014) Paolo De Los Rios et al. eLife
- Molecular Chaperone Functions in Protein Folding and Proteostasis
- (2013) Yujin E. Kim et al. Annual Review of Biochemistry
- The Cotranslational Function of Ribosome-Associated Hsp70 in Eukaryotic Protein Homeostasis
- (2013) Felix Willmund et al. CELL
- PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone
- (2013) Sae-Hun Park et al. CELL
- Real-time observation of the conformational dynamics of mitochondrial Hsp70 by spFRET
- (2013) Martin Sikor et al. EMBO JOURNAL
- The nascent polypeptide-associated complex is a key regulator of proteostasis
- (2013) Janine Kirstein-Miles et al. EMBO JOURNAL
- Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway
- (2013) Anna Shemorry et al. MOLECULAR CELL
- Principles of Cotranslational Ubiquitination and Quality Control at the Ribosome
- (2013) Stefanie Duttler et al. MOLECULAR CELL
- Reshaping of the conformational search of a protein by the chaperone trigger factor
- (2013) Alireza Mashaghi et al. NATURE
- Non-optimal codon usage affects expression, structure and function of clock protein FRQ
- (2013) Mian Zhou et al. NATURE
- Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress
- (2013) Stéphanie Escusa-Toret et al. NATURE CELL BIOLOGY
- Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP
- (2013) Ruifeng Qi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle
- (2013) Zhuo Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Crystal Structures of the Eukaryotic Chaperonin CCT Reveal Its Functional Partitioning
- (2013) Nir Kalisman et al. STRUCTURE
- Hsp70 chaperone dynamics and molecular mechanism
- (2013) Matthias P. Mayer TRENDS IN BIOCHEMICAL SCIENCES
- The chaperone Hsp90: changing partners for demanding clients
- (2013) Alina Röhl et al. TRENDS IN BIOCHEMICAL SCIENCES
- Protein Folding in the Endoplasmic Reticulum
- (2013) I. Braakman et al. Cold Spring Harbor Perspectives in Biology
- Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins
- (2013) Prajwal Ciryam et al. Cell Reports
- Pharmacological brake-release of mRNA translation enhances cognitive memory
- (2013) Carmela Sidrauski et al. eLife
- Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
- (2012) Mikko Taipale et al. CELL
- ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the GroEL Chaperonin
- (2012) Daniel K. Clare et al. CELL
- The Therapeutic Target Hsp90 and Cancer Hallmarks
- (2012) Yoshihiko Miyata et al. CURRENT PHARMACEUTICAL DESIGN
- Metazoan Hsp70 machines use Hsp110 to power protein disaggregation
- (2012) Heike Rampelt et al. EMBO JOURNAL
- Silent Substitutions Predictably Alter Translation Elongation Rates and Protein Folding Efficiencies
- (2012) Paige S. Spencer et al. JOURNAL OF MOLECULAR BIOLOGY
- Structure and Allostery of the Chaperonin GroEL
- (2012) Helen R. Saibil et al. JOURNAL OF MOLECULAR BIOLOGY
- Ribosome-Associated Complex and Ssb Are Required for Translational Repression Induced by Polylysine Segments within Nascent Chains
- (2012) M. Chiabudini et al. MOLECULAR AND CELLULAR BIOLOGY
- NAC functions as a modulator of SRP during the early steps of protein targeting to the endoplasmic reticulum
- (2012) Ying Zhang et al. MOLECULAR BIOLOGY OF THE CELL
- Concerted Action of the Ribosome and the Associated Chaperone Trigger Factor Confines Nascent Polypeptide Folding
- (2012) Anja Hoffmann et al. MOLECULAR CELL
- Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones
- (2012) Roman Kityk et al. MOLECULAR CELL
- The anti-Shine–Dalgarno sequence drives translational pausing and codon choice in bacteria
- (2012) Gene-Wei Li et al. NATURE
- Increased proteasome activity in human embryonic stem cells is regulated by PSMD11
- (2012) David Vilchez et al. NATURE
- Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT
- (2012) F. Russmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Subunit order of eukaryotic TRiC/CCT chaperonin by cross-linking, mass spectrometry, and combinatorial homology modeling
- (2012) N. Kalisman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT
- (2012) Alexander Leitner et al. STRUCTURE
- Ribosome-associated chaperones as key players in proteostasis
- (2012) Steffen Preissler et al. TRENDS IN BIOCHEMICAL SCIENCES
- DnaK Functions as a Central Hub in the E. coli Chaperone Network
- (2012) Giulia Calloni et al. Cell Reports
- SERF Protein Is a Direct Modifier of Amyloid Fiber Assembly
- (2012) S. Fabio Falsone et al. Cell Reports
- A Gradient of ATP Affinities Generates an Asymmetric Power Stroke Driving the Chaperonin TRIC/CCT Folding Cycle
- (2012) Stefanie Reissmann et al. Cell Reports
- Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease
- (2011) Julius Anckar et al. Annual Review of Biochemistry
- The Hsp90 chaperone machinery: Conformational dynamics and regulation by co-chaperones
- (2011) Jing Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber
- (2011) Nicholai R. Douglas et al. CELL
- Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions
- (2011) Heidi Olzscha et al. CELL
- Selective Ribosome Profiling Reveals the Cotranslational Chaperone Action of Trigger Factor In Vivo
- (2011) Eugene Oh et al. CELL
- The ribosomal tunnel as a functional environment for nascent polypeptide folding and translational stalling
- (2011) Daniel N Wilson et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- New Scenarios of Protein Folding Can Occur on the Ribosome
- (2011) Edward P. O’Brien et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Substrate Binding Drives Large-Scale Conformational Changes in the Hsp90 Molecular Chaperone
- (2011) Timothy O. Street et al. MOLECULAR CELL
- Small-molecule proteostasis regulators for protein conformational diseases
- (2011) Barbara Calamini et al. Nature Chemical Biology
- Knot formation in newly translated proteins is spontaneous and accelerated by chaperonins
- (2011) Anna L Mallam et al. Nature Chemical Biology
- Firefly luciferase mutants as sensors of proteome stress
- (2011) Rajat Gupta et al. NATURE METHODS
- The Ribosome Modulates Nascent Protein Folding
- (2011) C. M. Kaiser et al. SCIENCE
- Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis
- (2011) P. Tsaytler et al. SCIENCE
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Aging as an Event of Proteostasis Collapse
- (2011) R. C. Taylor et al. Cold Spring Harbor Perspectives in Biology
- Defining the Specificity of Cotranslationally Acting Chaperones by Systematic Analysis of mRNAs Associated with Ribosome-Nascent Chain Complexes
- (2011) Marta del Alamo et al. PLOS BIOLOGY
- Chaperone-assisted degradation: multiple paths to destruction
- (2010) Nadja Kettern et al. BIOLOGICAL CHEMISTRY
- Chaperonin-Catalyzed Rescue of Kinetically Trapped States in Protein Folding
- (2010) Kausik Chakraborty et al. CELL
- A systematic survey of in vivo obligate chaperonin-dependent substrates
- (2010) Kei Fujiwara et al. EMBO JOURNAL
- Biological and Structural Basis for Aha1 Regulation of Hsp90 ATPase Activity in Maintaining Proteostasis in the Human Disease Cystic Fibrosis
- (2010) Atanas V. Koulov et al. MOLECULAR BIOLOGY OF THE CELL
- A Nucleus-based Quality Control Mechanism for Cytosolic Proteins
- (2010) Rupali Prasad et al. MOLECULAR BIOLOGY OF THE CELL
- The Three-Dimensional Organization of Polyribosomes in Intact Human Cells
- (2010) Florian Brandt et al. MOLECULAR CELL
- Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1
- (2010) Marco Retzlaff et al. MOLECULAR CELL
- Enhancement of proteasome activity by a small-molecule inhibitor of USP14
- (2010) Byung-Hoon Lee et al. NATURE
- The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase
- (2010) Sandeep K Sharma et al. Nature Chemical Biology
- HSP90 at the hub of protein homeostasis: emerging mechanistic insights
- (2010) Mikko Taipale et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The HSP70 chaperone machinery: J proteins as drivers of functional specificity
- (2010) Harm H. Kampinga et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mixed Hsp90–cochaperone complexes are important for the progression of the reaction cycle
- (2010) Jing Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopy
- (2010) C. Eichmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cellular strategies for the assembly of molecular machines
- (2010) Ashwin Chari et al. TRENDS IN BIOCHEMICAL SCIENCES
- Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
- (2009) Evan T. Powers et al. Annual Review of Biochemistry
- The Native 3D Organization of Bacterial Polysomes
- (2009) Florian Brandt et al. CELL
- Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
- (2009) Martin Gamerdinger et al. EMBO JOURNAL
- The GroEL/GroES cis cavity as a passive anti-aggregation device
- (2009) Arthur L. Horwich et al. FEBS LETTERS
- Tertiary interactions within the ribosomal exit tunnel
- (2009) Andrey Kosolapov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis
- (2009) Moritz Mickler et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90
- (2009) Martin Hessling et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1
- (2009) J. W. Heck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
- (2009) A. Ben-Zvi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Analytical Solution to the Kinetics of Breakable Filament Assembly
- (2009) T. P. J. Knowles et al. SCIENCE
- Monitoring Protein Conformation along the Pathway of Chaperonin-Assisted Folding
- (2008) Shruti Sharma et al. CELL
- Function and structure of inherently disordered proteins
- (2008) A Keith Dunker et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Misfolded proteins partition between two distinct quality control compartments
- (2008) Daniel Kaganovich et al. NATURE
- The structure of CCT–Hsc70NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin
- (2008) Jorge Cuéllar et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- GroEL stimulates protein folding through forced unfolding
- (2008) Zong Lin et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now