Journal
NATURE METHODS
Volume 8, Issue 3, Pages 221-229Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.1570
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Funding
- Cluster for Integrated Protein Science Munich
- Technische Universitat Munchen Institute for Advanced Study
- Alexander von Humboldt fellowship
- Technische Universitat Munchen graduate school Materials at Complex Interfaces (CompInt)
- German Excellence Initiative
- Elite Network of the state of Bavaria
- Massachusetts Institute of Technology
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Molecular self-assembly with scaffolded DNA origami enables building custom-shaped nanometer-scale objects with molecular weights in the megadalton regime. Here we provide a practical guide for design and assembly of scaffolded DNA origami objects. We also introduce a computational tool for predicting the structure of DNA origami objects and provide information on the conditions under which DNA origami objects can be expected to maintain their structure.
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