Synthetic Genetic Polymers Capable of Heredity and Evolution

Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor

(2012) Hanyang Yu et al.   Nature Chemistry

Locked vs. unlocked nucleic acids (LNA vs. UNA): contrasting structures work towards common therapeutic goals

(2011) Meghan A. Campbell et al.   CHEMICAL SOCIETY REVIEWS

Nucleic Acids with a Six-Membered ‘Carbohydrate’ Mimic in the Backbone

(2010) Piet Herdewijn   CHEMISTRY & BIODIVERSITY

Biophysical characterization of DNA and RNA aptamer interactions with hen egg lysozyme

(2010) Ajish S.R. Potty et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

CyDNA: Synthesis and Replication of Highly Cy-Dye Substituted DNA by an Evolved Polymerase

(2010) Nicola Ramsay et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the Chemistry of DNA for in Vitro Selection

(2010) Jonathan D. Vaught et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An in vitro translation, selection and amplification system for peptide nucleic acids

(2010) Yevgeny Brudno et al.   Nature Chemical Biology

Structural Insight into Translesion Synthesis by DNA Pol II

(2009) Feng Wang et al.   CELL

Polymerase engineering: towards the encoded synthesis of unnatural biopolymers

(2009) David Loakes et al.   CHEMICAL COMMUNICATIONS

Advances and pitfalls of protein structural alignment

(2009) Hitomi Hasegawa et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Evolving a Polymerase for Hydrophobic Base Analogues

(2009) David Loakes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient and Rapid Template-Directed Nucleic Acid Copying Using 2′-Amino-2′,3′-dideoxyribonucleoside−5′-Phosphorimidazolide Monomers

(2009) Jason P. Schrum et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ

(2009) Michael K Swan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus

(2008) Suhng Wook Kim et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography

(2008) Susan J. Firbank et al.   JOURNAL OF MOLECULAR BIOLOGY

Discovery, Characterization, and Optimization of an Unnatural Base Pair for Expansion of the Genetic Alphabet

(2008) Aaron M. Leconte et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY