Amyloid β-targeted metal complexes for potential applications in Alzheimer's disease
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Amyloid β-targeted metal complexes for potential applications in Alzheimer's disease
Authors
Keywords
-
Journal
Future Medicinal Chemistry
Volume 10, Issue 6, Pages 679-701
Publisher
Future Science, LTD
Online
2018-02-05
DOI
10.4155/fmc-2017-0248
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mechanistic Insights into Tunable Metal-Mediated Hydrolysis of Amyloid-β Peptides
- (2017) Jeffrey S. Derrick et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent progress in the development of metal complexes as β-amyloid imaging probes in the brain
- (2017) Kaihua Chen et al. MedChemComm
- Synthesis and biological evaluation of novel technetium-99m-labeled phenylquinoxaline derivatives as single photon emission computed tomography imaging probes targeting β-amyloid plaques in Alzheimer's disease
- (2017) Shimpei Iikuni et al. RSC Advances
- Bis (thiosemicarbazonato) Cu-64 Complexes for Positron Emission Tomography Imaging of Alzheimer's Disease
- (2017) Michelle T. Fodero-Tavoletti et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid imaging: Past, present and future perspectives
- (2016) Victor L. Villemagne AGEING RESEARCH REVIEWS
- 68Ga-Bivalent Polypegylated Styrylpyridine Conjugates for Imaging Aβ Plaques in Cerebral Amyloid Angiopathy
- (2016) Zhihao Zha et al. BIOCONJUGATE CHEMISTRY
- 99mTc-Labeled 2-Arylbenzothiazoles: Aβ Imaging Probes with Favorable Brain Pharmacokinetics for Single-Photon Emission Computed Tomography
- (2016) Xiaoyang Zhang et al. BIOCONJUGATE CHEMISTRY
- A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation
- (2016) Yinhui Li et al. BIOMATERIALS
- Synthesis and evaluation of copper-64 labeled benzofuran derivatives targeting β-amyloid aggregates
- (2016) Hiroyuki Watanabe et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Specific self-monitoring of metal-associated amyloid-β peptide disaggregation by a fluorescent chelator
- (2016) Tao Yang et al. CHEMICAL COMMUNICATIONS
- The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
- (2016) Timothy C. Johnstone et al. CHEMICAL REVIEWS
- Detection of Aβ Monomers and Oligomers: Early Diagnosis of Alzheimer's Disease
- (2016) Yanli Zhou et al. Chemistry-An Asian Journal
- Alzheimer's disease: The use of contrast agents for magnetic resonance imaging to detect amyloid beta peptide inside the brain
- (2016) Milena Salerno et al. COORDINATION CHEMISTRY REVIEWS
- Recent progress in multifunctional metal chelators as potential drugs for Alzheimer's disease
- (2016) M. Amélia Santos et al. COORDINATION CHEMISTRY REVIEWS
- Interactions between proteins and Ru compounds of medicinal interest: A structural perspective
- (2016) Antonello Merlino COORDINATION CHEMISTRY REVIEWS
- 2-Arylbenzothiazoles labeled with [CpRe/ 99m Tc(CO) 3 ] and evaluated as β -amyloid imaging probes
- (2016) Jianhua Jia et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Ruthenium(II) polypyridyl complexes with hydrophobic ancillary ligand as Aβ aggregation inhibitors
- (2016) Nilima A. Vyas et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Recent progress in repositioning Alzheimer's disease drugs based on a multitarget strategy
- (2016) M Amélia Santos et al. Future Medicinal Chemistry
- A gallium(III) Schiff base-curcumin complex that binds to amyloid-β plaques
- (2016) Jaclyn L. Lange et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- From Companion Diagnostics to Theranostics: A New Avenue for Alzheimer’s Disease?
- (2016) Maria Laura Bolognesi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Luminescent Ru(II) Phenanthroline Complexes as a Probe for Real-Time Imaging of Aβ Self-Aggregation and Therapeutic Applications in Alzheimer’s Disease
- (2016) Debora E. S. Silva et al. JOURNAL OF MEDICINAL CHEMISTRY
- Unprecedented Dual Light-Switching Response of a Metal Dipyridophenazine Complex toward Amyloid-β Aggregation
- (2016) Amir Aliyan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis and Evaluation of a Zr-89-Labeled Monoclonal Antibody for Immuno-PET Imaging of Amyloid-β Deposition in the Brain
- (2016) Jens Fissers et al. MOLECULAR IMAGING AND BIOLOGY
- A copper–amyloid-β targeted fluorescent chelator as a potential theranostic agent for Alzheimer's disease
- (2016) Tao Yang et al. Inorganic Chemistry Frontiers
- Site-selective recognition of peptide phosphorylation by a terbium(iii) complex in aqueous solution
- (2015) Xiaohui Wang et al. CHEMICAL COMMUNICATIONS
- Function and toxicity of amyloid beta and recent therapeutic interventions targeting amyloid beta in Alzheimer's disease
- (2015) K. Rajasekhar et al. CHEMICAL COMMUNICATIONS
- Small conjugate-based theranostic agents: an encouraging approach for cancer therapy
- (2015) Rajesh Kumar et al. CHEMICAL SOCIETY REVIEWS
- Interaction of PiB-Derivative Metal Complexes with Beta-Amyloid Peptides: Selective Recognition of the Aggregated Forms
- (2015) André F. Martins et al. CHEMISTRY-A EUROPEAN JOURNAL
- 2-Phenylbenzothiazole conjugated with cyclopentadienyl tricarbonyl [CpM(CO)3] (M = Re, 99mTc) complexes as potential imaging probes for β-amyloid plaques
- (2015) Jianhua Jia et al. DALTON TRANSACTIONS
- Rhenium and technetium complexes that bind to amyloid-β plaques
- (2015) David J. Hayne et al. DALTON TRANSACTIONS
- 99mTc-labeled-2-arylbenzoxazole derivatives as potential Aβ imaging probes for single-photon emission computed tomography
- (2015) Xuedan Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Associating a negatively charged GdDOTA-derivative to the Pittsburgh compound B for targeting Aβ amyloid aggregates
- (2015) André F. Martins et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Curcumin Targeted, Polymalic Acid-Based MRI Contrast Agent for the Detection of Aβ Plaques in Alzheimer's Disease
- (2015) Rameshwar Patil et al. MACROMOLECULAR BIOSCIENCE
- Modulation of the Aβ peptide aggregation pathway by KP1019 limits Aβ-associated neurotoxicity
- (2015) Michael R. Jones et al. Metallomics
- Methionine oxidation of amyloid peptides by peroxovanadium complexes: inhibition of fibril formation through a distinct mechanism
- (2015) Lei He et al. Metallomics
- Gallium-68 Complexes Conjugated to Pittsburgh Compound B: Radiolabeling and Biological Evaluation
- (2015) Damien Cressier et al. MOLECULAR IMAGING AND BIOLOGY
- Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer’s Drug Discovery
- (2015) Xian-Le Bu et al. MOLECULAR NEUROBIOLOGY
- Understanding Biomarkers of Neurodegeneration: Ultrasensitive detection techniques pave the way for mechanistic understanding
- (2015) Kaj Blennow et al. NATURE MEDICINE
- Gadolinium-complexed Aβ-binding contrast agents for MRI diagnosis of Alzheimer's Disease
- (2015) Balpreet Matharu et al. NEUROPEPTIDES
- Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease
- (2015) Sagar H. Barage et al. NEUROPEPTIDES
- Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake
- (2015) Maarten Rotman et al. NUCLEAR MEDICINE AND BIOLOGY
- Sensing and inhibition of amyloid-β based on the simple luminescent aptamer–ruthenium complex system
- (2015) Eththilu Babu et al. TALANTA
- Metal complexes as potential modulators of inflammatory and autoimmune responses
- (2015) Chung-Hang Leung et al. Chemical Science
- Recent advances in molecular imaging probes for β-amyloid plaques
- (2015) Masahiro Ono et al. MedChemComm
- Inhibition of Beta-Amyloid Fibrillation by Luminescent Iridium(III) Complex Probes
- (2015) Lihua Lu et al. Scientific Reports
- Organoiridium Complexes: Anticancer Agents and Catalysts
- (2014) Zhe Liu et al. ACCOUNTS OF CHEMICAL RESEARCH
- The Ongoing Search for Small Molecules to Study Metal-Associated Amyloid-β Species in Alzheimer’s Disease
- (2014) Masha G. Savelieff et al. ACCOUNTS OF CHEMICAL RESEARCH
- Group 9 Organometallic Compounds for Therapeutic and Bioanalytical Applications
- (2014) Dik-Lung Ma et al. ACCOUNTS OF CHEMICAL RESEARCH
- A 68Ga complex based on benzofuran scaffold for the detection of β-amyloid plaques
- (2014) Hiroyuki Watanabe et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Modulation of Amyloid-β Aggregation by Histidine-Coordinating Cobalt(III) Schiff Base Complexes
- (2014) Marie C. Heffern et al. CHEMBIOCHEM
- Binuclear ruthenium(II) complexes for amyloid fibrils recognition
- (2014) Piotr Hanczyc CHEMICAL PHYSICS
- Metallodrugs in Medicinal Inorganic Chemistry
- (2014) Katja Dralle Mjos et al. CHEMICAL REVIEWS
- Metal complexes designed to bind to amyloid-β for the diagnosis and treatment of Alzheimer's disease
- (2014) David J. Hayne et al. CHEMICAL SOCIETY REVIEWS
- Recent developments in lanthanide-based luminescent probes
- (2014) Xiaohui Wang et al. COORDINATION CHEMISTRY REVIEWS
- Platinoid complexes to target monomeric disordered peptides: a forthcoming solution against amyloid diseases?
- (2014) Christelle Hureau et al. DALTON TRANSACTIONS
- Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI
- (2014) Guillaume Bort et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Ruthenium(II) polypyridyl complex as inhibitor of acetylcholinesterase and Aβ aggregation
- (2014) Nilima A. Vyas et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Characterization of 68Ga-Labeled Curcumin and Curcuminoid Complexes as Potential Radiotracers for Imaging of Cancer and Alzheimer’s Disease
- (2014) Mattia Asti et al. INORGANIC CHEMISTRY
- Synthesis of 2-Pyridyl-benzimidazole Iridium(III), Ruthenium(II), and Platinum(II) Complexes. Study of the Activity as Inhibitors of Amyloid-β Aggregation and Neurotoxicity Evaluation
- (2014) Gorakh S. Yellol et al. INORGANIC CHEMISTRY
- Enhancement of Binding Affinity for Amyloid Aggregates by Multivalent Interactions of 99mTc-Hydroxamamide Complexes
- (2014) Shimpei Iikuni et al. MOLECULAR PHARMACEUTICS
- Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease
- (2014) Kirsten L. Viola et al. Nature Nanotechnology
- The amyloid state and its association with protein misfolding diseases
- (2014) Tuomas P. J. Knowles et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- 68Ga based probe for Alzheimer's disease: synthesis and preclinical evaluation of homodimeric chalcone in β-amyloid imaging
- (2014) Kanchan Chauhan et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Alkoxy bridged binuclear rhenium (I) complexes as a potential sensor for β-amyloid aggregation
- (2014) Veerasamy Sathish et al. TALANTA
- Untangling Amyloid-β, Tau, and Metals in Alzheimer’s Disease
- (2013) Masha G. Savelieff et al. ACS Chemical Biology
- Positron Emission Tomography Imaging of Fibrillar Parenchymal and Vascular Amyloid-β in TgCRND8 Mice
- (2013) Daniel McLean et al. ACS Chemical Neuroscience
- Development of a Platinum Complex as an anti-Amyloid Agent for the Therapy of Alzheimer’s Disease
- (2013) Vijaya B. Kenche et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Pt(ii) compounds interplay with Cu(ii) and Zn(ii) coordination to the amyloid-β peptide has metal specific consequences on deleterious processes associated to Alzheimer's disease
- (2013) Fabrice Collin et al. CHEMICAL COMMUNICATIONS
- Synthesis, conjugation and relaxation studies of gadolinium(iii)-4-benzothiazol-2-yl-phenylamine as a potential brain specific MR contrast agent
- (2013) Nisha Saini et al. DALTON TRANSACTIONS
- Next-Generation Metal Anticancer Complexes: Multitargeting via Redox Modulation
- (2013) Isolda Romero-Canelón et al. INORGANIC CHEMISTRY
- Gd3+ complexes conjugated to Pittsburgh compound B: potential MRI markers of β-amyloid plaques
- (2013) André F. Martins et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Target-specific Tc(CO)3-complexes for in vivo imaging
- (2013) Maurício Morais et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Diagnostic Imaging Agents for Alzheimer’s Disease: Copper Radiopharmaceuticals that Target Aβ Plaques
- (2013) James L. Hickey et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Unraveling the Photoluminescence Response of Light-Switching Ruthenium(II) Complexes Bound to Amyloid-β
- (2013) Nathan P. Cook et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of β-Amyloid Plaques
- (2013) André F. Martins et al. ACS Medicinal Chemistry Letters
- Promising in Vitro anti-Alzheimer Properties for a Ruthenium(III) Complex
- (2013) Luigi Messori et al. ACS Medicinal Chemistry Letters
- 2012 Alzheimer’s disease facts and figures
- (2012) Alzheimers & Dementia
- Synthesis and biological evaluation of novel technetium-99m labeled phenylbenzoxazole derivatives as potential imaging probes for β-amyloid plaques in brain
- (2012) Xuedan Wang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Bioinorganic Chemistry of Alzheimer’s Disease
- (2012) Kasper P. Kepp CHEMICAL REVIEWS
- Werner coordination chemistry and neurodegeneration
- (2012) Maria A. Telpoukhovskaia et al. CHEMICAL SOCIETY REVIEWS
- Targeting and delivery of platinum-based anticancer drugs
- (2012) Xiaoyong Wang et al. CHEMICAL SOCIETY REVIEWS
- Diagnostic imaging of Alzheimer's disease with copper and technetium complexes
- (2012) James L. Hickey et al. COORDINATION CHEMISTRY REVIEWS
- Metal compounds as inhibitors of β-amyloid aggregation. Perspectives for an innovative metallotherapeutics on Alzheimer's disease
- (2012) Daniela Valensin et al. COORDINATION CHEMISTRY REVIEWS
- Metal-associated amyloid-β species in Alzheimer's disease
- (2012) Amit S Pithadia et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Ultrasound-Induced Blood-Brain Barrier Opening
- (2012) Elisa E. Konofagou et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- The potentiality of vanadium in medicinal applications
- (2012) Dieter Rehder Future Medicinal Chemistry
- Technetium-99m Labeled Pyridyl Benzofuran Derivatives as Single Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Alzheimer’s Brains
- (2012) Yan Cheng et al. JOURNAL OF MEDICINAL CHEMISTRY
- Novel Cyclopentadienyl Tricarbonyl Complexes of 99mTc Mimicking Chalcone as Potential Single-Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Brain
- (2012) Zijing Li et al. JOURNAL OF MEDICINAL CHEMISTRY
- The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
- (2012) Iryna Benilova et al. NATURE NEUROSCIENCE
- Curcumin Promotes A-beta Fibrillation and Reduces Neurotoxicity in Transgenic Drosophila
- (2012) Ina Caesar et al. PLoS One
- Preventing Alzheimer's Disease
- (2012) D. J. Selkoe SCIENCE
- Development of Positron Emission Tomography β-Amyloid Plaque Imaging Agents
- (2012) Chester A. Mathis et al. SEMINARS IN NUCLEAR MEDICINE
- Inhibitory action of macrocyclic platiniferous chelators on metal-induced Aβ aggregation
- (2012) Xiaohui Wang et al. Chemical Science
- Theranostics: Combining Imaging and Therapy
- (2011) Sneha S. Kelkar et al. BIOCONJUGATE CHEMISTRY
- Sensing Amyloid-β Aggregation Using Luminescent Dipyridophenazine Ruthenium(II) Complexes
- (2011) Nathan P. Cook et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils
- (2011) Jan Bieschke et al. Nature Chemical Biology
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
- (2011) Eric Karran et al. NATURE REVIEWS DRUG DISCOVERY
- Gadolinium-staining reveals amyloid plaques in the brain of Alzheimer's transgenic mice
- (2011) Alexandra Petiet et al. NEUROBIOLOGY OF AGING
- Group 9 metal-based inhibitors of β-amyloid (1–40) fibrillation as potential therapeutic agents for Alzheimer's disease
- (2011) Bradley Yat-Wah Man et al. Chemical Science
- Inhibition of Aβ42 Peptide Aggregation by a Binuclear Ruthenium(II)−Platinum(II) Complex: Potential for Multimetal Organometallics as Anti-amyloid Agents
- (2010) Amit Kumar et al. ACS Chemical Neuroscience
- A copper radiopharmaceutical for diagnostic imaging of Alzheimer's disease: a bis(thiosemicarbazonato)copper(ii) complex that binds to amyloid-β plaques
- (2010) SinChun Lim et al. CHEMICAL COMMUNICATIONS
- Phosphorescent chemosensors based on heavy-metal complexes
- (2010) Qiang Zhao et al. CHEMICAL SOCIETY REVIEWS
- fac-{Ru(CO)3}2+Selectively Targets the Histidine Residues of the β-Amyloid Peptide 1-28. Implications for New Alzheimer's Disease Treatments Based on Ruthenium Complexes
- (2010) Daniela Valensin et al. INORGANIC CHEMISTRY
- New chelating ligands for Co(III)-based peptide-cleaving catalysts selective for pathogenic proteins of amyloidoses
- (2010) Woo Suk Chei et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Biomarkers in Alzheimer's disease drug development
- (2010) Kaj Blennow NATURE MEDICINE
- Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives
- (2010) Harald Hampel et al. NATURE REVIEWS DRUG DISCOVERY
- Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease
- (2010) Lars M. Ittner et al. NATURE REVIEWS NEUROSCIENCE
- Design of small molecules that target metal-A species and regulate metal-induced A aggregation and neurotoxicity
- (2010) J.-S. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Imaging of Cancer with Copper-64 Radiopharmaceuticals and Positron Emission Tomography (PET)
- (2009) Monica Shokeen et al. ACCOUNTS OF CHEMICAL RESEARCH
- Alzheimer's Disease: From Pathology to Therapeutic Approaches
- (2009) Roland Jakob-Roetne et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The chemistry of Alzheimer’s disease
- (2009) Arvi Rauk CHEMICAL SOCIETY REVIEWS
- Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs
- (2009) Sabine H. van Rijt et al. DRUG DISCOVERY TODAY
- 18F Stilbenes and Styrylpyridines for PET Imaging of Aβ Plaques in Alzheimer’s Disease: A Miniperspective
- (2009) Hank F. Kung et al. JOURNAL OF MEDICINAL CHEMISTRY
- Chelation therapy for neurodegenerative diseases
- (2009) Silvia Bolognin et al. MEDICINAL RESEARCH REVIEWS
- Multimodal techniques for diagnosis and prognosis of Alzheimer's disease
- (2009) Richard J. Perrin et al. NATURE
- Alzheimer's disease
- (2009) Lennart Mucke NATURE
- KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients
- (2008) Christian G. Hartinger et al. CHEMISTRY & BIODIVERSITY
- Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide
- (2008) Peter Faller et al. DALTON TRANSACTIONS
- Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial
- (2008) Lars Lannfelt et al. LANCET NEUROLOGY
- Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ
- (2008) Paul A. Adlard et al. NEURON
- Platinum-based inhibitors of amyloid- as therapeutic agents for Alzheimer's disease
- (2008) K. J. Barnham et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now