Curcumin Promotes A-beta Fibrillation and Reduces Neurotoxicity in Transgenic Drosophila

Observations in APP Bitransgenic Mice Suggest that Diffuse and Compact Plaques Form via Independent Processes in Alzheimer's Disease

(2011) Anna Lord et al.   AMERICAN JOURNAL OF PATHOLOGY

Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan

(2011) Silvestre Alavez et al.   NATURE

A Fluorescent Pentameric Thiophene Derivative Detects in Vitro-Formed Prefibrillar Protein Aggregates

(2010) Per Hammarström et al.   BIOCHEMISTRY

Intrinsic Determinants of Neurotoxic Aggregate Formation by the Amyloid β Peptide

(2010) Ann-Christin Brorsson et al.   BIOPHYSICAL JOURNAL

Efficient imaging of amyloid deposits in Drosophila models of human amyloidoses

(2010) Ina Berg et al.   Nature Protocols

Sequestration of the Aβ Peptide Prevents Toxicity and Promotes Degradation In Vivo

(2010) Leila M. Luheshi et al.   PLOS BIOLOGY

Novel Pentameric Thiophene Derivatives forin Vitroandin VivoOptical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses

(2009) Andreas Åslund et al.   ACS Chemical Biology

Phenolic Compounds Prevent Alzheimer’s Pathology through Different Effects on the Amyloid-β Aggregation Pathway

(2009) Tsuyoshi Hamaguchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Fenton chemistry and oxidative stress mediate the toxicity of the β-amyloid peptide in aDrosophilamodel of Alzheimer’s disease

(2009) Thomas Rival et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

 -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin

(2009) Q.-L. Ma et al.   JOURNAL OF NEUROSCIENCE

Design, Synthesis, and Testing of Difluoroboron-Derivatized Curcumins as Near-Infrared Probes for in Vivo Detection of Amyloid-β Deposits

(2009) Chongzhao Ran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular amyloid formation in muscle cells of Aβ-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification

(2009) Alicia N Minniti et al.   Molecular Neurodegeneration

Modeling Familial Amyloidotic Polyneuropathy (Transthyretin V30M) in Drosophila melanogaster

(2009) Ina Berg et al.   Neurodegenerative Diseases

Potential protection of curcumin against amyloid β-induced toxicity on cultured rat prefrontal cortical neurons

(2009) Xiao-Yan Qin et al.   NEUROSCIENCE LETTERS

Consumption of Grape Seed Extract Prevents Amyloid-β Deposition and Attenuates Inflammation in Brain of an Alzheimer’s Disease Mouse

(2009) Yan-Jiang Wang et al.   NEUROTOXICITY RESEARCH

 -Helix targeting reduces amyloid-  peptide toxicity

(2009) C. Nerelius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

(2008) Preetha Anand et al.   BIOCHEMICAL PHARMACOLOGY

Aminostyrylbenzofuran derivatives as potent inhibitors for Aβ fibril formation

(2008) Ji Hun Byun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Curcumin protected PC12 cells against beta-amyloid-induced toxicity through the inhibition of oxidative damage and tau hyperphosphorylation

(2008) So-Young Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

(2008) A. N. Begum et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A highly insoluble state of Aβ similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice

(2008) Ola Philipson et al.   NEUROBIOLOGY OF AGING

Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: Blockage by curcumin

(2008) Raozhou Lin et al.   NEUROSCIENCE LETTERS