Modulation of the Aβ peptide aggregation pathway by KP1019 limits Aβ-associated neurotoxicity
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Modulation of the Aβ peptide aggregation pathway by KP1019 limits Aβ-associated neurotoxicity
Authors
Keywords
-
Journal
Metallomics
Volume 7, Issue 1, Pages 129-135
Publisher
Royal Society of Chemistry (RSC)
Online
2014-11-03
DOI
10.1039/c4mt00252k
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Endogenous Polyamines Reduce the Toxicity of Soluble Aβ Peptide Aggregates Associated with Alzheimer’s Disease
- (2014) Jinghui Luo et al. BIOMACROMOLECULES
- Metal complexes designed to bind to amyloid-β for the diagnosis and treatment of Alzheimer's disease
- (2014) David J. Hayne et al. CHEMICAL SOCIETY REVIEWS
- Platinoid complexes to target monomeric disordered peptides: a forthcoming solution against amyloid diseases?
- (2014) Christelle Hureau et al. DALTON TRANSACTIONS
- Nuclear Translocation Uncovers the Amyloid Peptide Aβ42 as a Regulator of Gene Transcription
- (2014) Christian Barucker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MLK3-MKK3/6-P38MAPK cascades following N-methyl-D-aspartate receptor activation contributes to amyloid-β peptide-induced apoptosis in SH-SY5Y cells
- (2014) Fang Zhou et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Mid-range molecular weight oligomers in the normal and Alzheimer brain: Clinico-pathological correlations
- (2014) Panteleimon Giannakopoulos et al. NEUROBIOLOGY OF AGING
- Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
- (2013) Qiuming Wang et al. ACS Chemical Neuroscience
- Development of a Platinum Complex as an anti-Amyloid Agent for the Therapy of Alzheimer’s Disease
- (2013) Vijaya B. Kenche et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Pt(ii) compounds interplay with Cu(ii) and Zn(ii) coordination to the amyloid-β peptide has metal specific consequences on deleterious processes associated to Alzheimer's disease
- (2013) Fabrice Collin et al. CHEMICAL COMMUNICATIONS
- Increasing the Bioavailability of RuIIIAnticancer Complexes through Hydrophobic Albumin Interactions
- (2013) Michael I. Webb et al. CHEMISTRY-A EUROPEAN JOURNAL
- Role of Metal Ions in the Self-assembly of the Alzheimer’s Amyloid-β Peptide
- (2013) Peter Faller et al. INORGANIC CHEMISTRY
- Rational Design of a Structural Framework with Potential Use to Develop Chemical Reagents That Target and Modulate Multiple Facets of Alzheimer’s Disease
- (2013) Sanghyun Lee et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- EPR as a probe of the intracellular speciation of ruthenium(iii) anticancer compounds
- (2013) Michael I. Webb et al. Metallomics
- The effect of Cu2+ and Zn2+ on the Aβ42 peptide aggregation and cellular toxicity
- (2013) Anuj K. Sharma et al. Metallomics
- Promising in Vitro anti-Alzheimer Properties for a Ruthenium(III) Complex
- (2013) Luigi Messori et al. ACS Medicinal Chemistry Letters
- Amyloid β-protein oligomers and Alzheimer’s disease
- (2013) Eric Y Hayden et al. Alzheimers Research & Therapy
- Alzheimer Mechanisms and Therapeutic Strategies
- (2012) Yadong Huang et al. CELL
- Bioinorganic Chemistry of Alzheimer’s Disease
- (2012) Kasper P. Kepp CHEMICAL REVIEWS
- Metal compounds as inhibitors of β-amyloid aggregation. Perspectives for an innovative metallotherapeutics on Alzheimer's disease
- (2012) Daniela Valensin et al. COORDINATION CHEMISTRY REVIEWS
- Interference of a new cyclometallated Pt compound with Cu binding to amyloid-β peptide
- (2012) Isabelle Sasaki et al. DALTON TRANSACTIONS
- Bifunctional Compounds for Controlling Metal-Mediated Aggregation of the Aβ42 Peptide
- (2012) Anuj K. Sharma et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Multivariate Analyses of Amyloid-Beta Oligomer Populations Indicate a Connection between Pore Formation and Cytotoxicity
- (2012) Panchika Prangkio et al. PLoS One
- Toxic fibrillar oligomers of amyloid- have cross- structure
- (2012) J. C. Stroud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer's disease
- (2011) Qin Nie et al. ACTA PHARMACOLOGICA SINICA
- Amyloid Precursor Protein Processing and Alzheimer's Disease
- (2011) Richard J. O'Brien et al. Annual Review of Neuroscience
- Misfolded proteins in Alzheimer's disease and type II diabetes
- (2011) Alaina S. DeToma et al. CHEMICAL SOCIETY REVIEWS
- Approaching tumour therapy beyond platinum drugs
- (2011) A. Bergamo et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils
- (2011) Jan Bieschke et al. Nature Chemical Biology
- Resolving controversies on the path to Alzheimer's therapeutics
- (2011) Dennis J Selkoe NATURE MEDICINE
- Group 9 metal-based inhibitors of β-amyloid (1–40) fibrillation as potential therapeutic agents for Alzheimer's disease
- (2011) Bradley Yat-Wah Man et al. Chemical Science
- Inhibition of Aβ42 Peptide Aggregation by a Binuclear Ruthenium(II)−Platinum(II) Complex: Potential for Multimetal Organometallics as Anti-amyloid Agents
- (2010) Amit Kumar et al. ACS Chemical Neuroscience
- Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
- (2010) Inna Kuperstein et al. EMBO JOURNAL
- fac-{Ru(CO)3}2+Selectively Targets the Histidine Residues of the β-Amyloid Peptide 1-28. Implications for New Alzheimer's Disease Treatments Based on Ruthenium Complexes
- (2010) Daniela Valensin et al. INORGANIC CHEMISTRY
- Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339
- (2010) Petra Heffeter et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Alzheimer's disease: strategies for disease modification
- (2010) Martin Citron NATURE REVIEWS DRUG DISCOVERY
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Truncated -amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome
- (2010) H. Jang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein-induced photophysical changes to the amyloid indicator dye thioflavin T
- (2010) L. S. Wolfe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
- (2010) Jan Bieschke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase I dose-escalation study
- (2009) Frederike Lentz et al. ANTI-CANCER DRUGS
- Serum-protein interactions with anticancer Ru(III) complexes KP1019 and KP418 characterized by EPR
- (2009) Naniye Cetinbas et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Structure-neurotoxicity relationships of amyloid -protein oligomers
- (2009) K. Ono et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients
- (2008) Christian G. Hartinger et al. CHEMISTRY & BIODIVERSITY
- Synthesis and Reactivity of the Aquation Product of the Antitumor Complextrans-[RuIIICl4(indazole)2]−
- (2008) Berta Cebrián-Losantos et al. INORGANIC CHEMISTRY
- Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer
- (2008) Rakez Kayed et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Classification of Toxic Amyloid Oligomers
- (2008) Charles G. Glabe JOURNAL OF BIOLOGICAL CHEMISTRY
- Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ
- (2008) Paul A. Adlard et al. NEURON
- Metal-Ligand Exchange Kinetics in Platinum and Ruthenium Complexes
- (2008) By Jan Reedijk
- Platinum-based inhibitors of amyloid- as therapeutic agents for Alzheimer's disease
- (2008) K. J. Barnham et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started