Rhenium and technetium complexes that bind to amyloid-β plaques

Metal complexes designed to bind to amyloid-β for the diagnosis and treatment of Alzheimer's disease

(2014) David J. Hayne et al.   CHEMICAL SOCIETY REVIEWS

Factors That Limit Positron Emission Tomography Imaging of P-Glycoprotein Density at the Blood–Brain Barrier

(2013) Pavitra Kannan et al.   MOLECULAR PHARMACEUTICS

Diagnostic imaging of Alzheimer's disease with copper and technetium complexes

(2012) James L. Hickey et al.   COORDINATION CHEMISTRY REVIEWS

Structural Modifications that Alter the P-Glycoprotein Efflux Properties of Compounds

(2012) Stephen A. Hitchcock   JOURNAL OF MEDICINAL CHEMISTRY

Novel Cyclopentadienyl Tricarbonyl Complexes of 99mTc Mimicking Chalcone as Potential Single-Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Brain

(2012) Zijing Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

(2012) Christopher M Clark et al.   LANCET NEUROLOGY

Brain Amyloid Imaging — FDA Approval of Florbetapir F18 Injection

(2012) Lucie Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synthesis of Rhenium(I) Tricarbonyl Complexes with Carbohydrate-Pendant Tridentate Ligands and Their Cellular Uptake

(2011) Yuji Mikata et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: A phase 2 trial

(2010) Rik Vandenberghe et al.   ANNALS OF NEUROLOGY

Sequential insertion of three different organometallics into a versatile building block containing a PNA backbone

(2010) Malay Patra et al.   DALTON TRANSACTIONS

Rational Design of Amyloid Binding Agents Based on the Molecular Rotor Motif

(2009) Jeyanthy Sutharsan et al.   ChemMedChem

18F Stilbenes and Styrylpyridines for PET Imaging of Aβ Plaques in Alzheimer’s Disease: A Miniperspective

(2009) Hank F. Kung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Preclinical Properties of 18F-AV-45: A PET Agent for A  Plaques in the Brain

(2009) S. R. Choi et al.   JOURNAL OF NUCLEAR MEDICINE

Synthesis and biological evaluation of 99mTc, Re-monoamine-monoamide conjugated to 2-(4-aminophenyl)benzothiazole as potential probes for β-amyloid plaques in the brain

(2008) Xiangji Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Expedient Multi-Step Synthesis of Organometallic Complexes of Tc and Re in High Effective Specific Activity. A New Platform for the Production of Molecular Imaging and Therapy Agents

(2008) Patrick W. Causey et al.   INORGANIC CHEMISTRY

Convenient Route Leading to Neutralfac-M(CO)3(NNO) Complexes (M = Re,99mTc) Coupled to Amine Pharmacophores

(2008) Aris Chiotellis et al.   INORGANIC CHEMISTRY

Rhenium complexes of chromophore-appended dipicolylamine ligands: syntheses, spectroscopic properties, DNA binding and X-ray crystal structure

(2008) Lucy A. Mullice et al.   NEW JOURNAL OF CHEMISTRY

Preparation and characterization of technetium and rhenium tricarbonyl complexes bearing the 4-nitrobenzyl moiety as potential bioreductive diagnostic radiopharmaceuticals. In vitro and in vivo studies

(2007) Javier Giglio et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY