Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake

Title
Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake
Authors
Keywords
VHH, Fc fusion, In labeling, APPswe/PS1dE9 mice, Biodistribution, SPECT
Journal
NUCLEAR MEDICINE AND BIOLOGY
Volume 42, Issue 8, Pages 695-702
Publisher
Elsevier BV
Online
2015-03-27
DOI
10.1016/j.nucmedbio.2015.03.003

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