Associating a negatively charged GdDOTA-derivative to the Pittsburgh compound B for targeting Aβ amyloid aggregates

Interaction of PiB-Derivative Metal Complexes with Beta-Amyloid Peptides: Selective Recognition of the Aggregated Forms

(2015) André F. Martins et al.   CHEMISTRY-A EUROPEAN JOURNAL

Inhibitory Activity of Curcumin Derivatives Towards Metal-Free and Metal-Induced Amyloid-β Aggregation

(2015) Akiko Kochi et al.   Current Alzheimer Research

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

(2015) Zane Jaunmuktane et al.   NATURE

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease

(2014) Eric Karran et al.   ANNALS OF NEUROLOGY

Metal complexes designed to bind to amyloid-β for the diagnosis and treatment of Alzheimer's disease

(2014) David J. Hayne et al.   CHEMICAL SOCIETY REVIEWS

Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI

(2014) Guillaume Bort et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gd3+ complexes conjugated to Pittsburgh compound B: potential MRI markers of β-amyloid plaques

(2013) André F. Martins et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease

(2013) Michelle A Erickson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Detection of Amyloid Plaques Targeted by Bifunctional USPIO in Alzheimer’s Disease Transgenic Mice Using Magnetic Resonance Microimaging

(2013) Youssef Zaim Wadghiri et al.   PLoS One

PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of β-Amyloid Plaques

(2013) André F. Martins et al.   ACS Medicinal Chemistry Letters

A multimodal, β-amyloid-targeted contrast agent

(2012) Sashiprabha M. Vithanarachchi et al.   CHEMICAL COMMUNICATIONS

DOTAGA-Anhydride: A Valuable Building Block for the Preparation of DOTA-Like Chelating Agents

(2012) Claire Bernhard et al.   CHEMISTRY-A EUROPEAN JOURNAL

Diagnostic imaging of Alzheimer's disease with copper and technetium complexes

(2012) James L. Hickey et al.   COORDINATION CHEMISTRY REVIEWS

Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment

(2012) V. Camus et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Technetium-99m Labeled Pyridyl Benzofuran Derivatives as Single Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Alzheimer’s Brains

(2012) Yan Cheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Amyloid-  Imaging with Pittsburgh Compound B and Florbetapir: Comparing Radiotracers and Quantification Methods

(2012) S. M. Landau et al.   JOURNAL OF NUCLEAR MEDICINE

Hydrophobicity and Conformational Change as Mechanistic Determinants for Nonspecific Modulators of Amyloid β Self-Assembly

(2011) Axel Abelein et al.   BIOCHEMISTRY

Improvement of Microscopic MR Imaging of Amyloid Plaques with Targeting and Non-Targeting Contrast Agents

(2011) Alexandra Petiet et al.   Current Medical Imaging Reviews

Properties, Solution State Behavior, and Crystal Structures of Chelates of DOTMA

(2011) Silvio Aime et al.   INORGANIC CHEMISTRY

Use of Florbetapir-PET for Imaging β-Amyloid Pathology

(2011) Christopher M. Clark   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Synthesis of lanthanide(III) complexes appended with a diphenylphosphinamide and their interaction with human serum albumin

(2011) Marco Giardiello et al.   JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY

Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study

(2011) Henryk Barthel et al.   LANCET NEUROLOGY

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide

(2011) Priyanka Narayan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gadolinium-staining reveals amyloid plaques in the brain of Alzheimer's transgenic mice

(2011) Alexandra Petiet et al.   NEUROBIOLOGY OF AGING

Detection of amyloid plaques targeted by USPIO-Aβ1–42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging

(2011) Jing Yang et al.   NEUROIMAGE

Synthesis and Evaluation of Novel Chalcone Derivatives with99mTc/Re Complexes as Potential Probes for Detection of β-Amyloid Plaques

(2010) Masahiro Ono et al.   ACS Chemical Neuroscience

18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: A phase 2 trial

(2010) Rik Vandenberghe et al.   ANNALS OF NEUROLOGY

Detergent-like Interaction of Congo Red with the Amyloid β Peptide

(2010) Christofer Lendel et al.   BIOCHEMISTRY

Synthesis and evaluation of novel benzothiazole derivatives based on the bithiophene structure as potential radiotracers for β-amyloid plaques in Alzheimer’s disease

(2010) Meng-Chao Cui et al.   BIOORGANIC & MEDICINAL CHEMISTRY

99mTc/Re complexes based on flavone and aurone as SPECT probes for imaging cerebral β-amyloid plaques

(2010) Masahiro Ono et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Blood-Borne Amyloid-  Dimer Correlates with Clinical Markers of Alzheimer's Disease

(2010) V. L. Villemagne et al.   JOURNAL OF NEUROSCIENCE

The use of PET in Alzheimer disease

(2010) Agneta Nordberg et al.   Nature Reviews Neurology

Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution

(2010) Harry Levine   PROTEIN SCIENCE

Surface Plasmon Resonance Binding Kinetics of Alzheimer’s Disease Amyloid β Peptide-Capturing and Plaque-Binding Monoclonal Antibodies

(2009) Muthu Ramakrishnan et al.   BIOCHEMISTRY

The chemistry of Alzheimer’s disease

(2009) Arvi Rauk   CHEMICAL SOCIETY REVIEWS

Lanthanide chelates of (bis)-hydroxymethyl-substituted DTTA with potential application as contrast agents in magnetic resonance imaging

(2009) Sara Silvério et al.   DALTON TRANSACTIONS

In vivo, in vitro and in silico methods for small molecule transfer across the BBB

(2009) Jurgen Mensch et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The role of positron emission tomography imaging of β-amyloid in patients with Alzheimerʼs disease

(2009) Kun-Lin Xiong et al.   NUCLEAR MEDICINE COMMUNICATIONS

The future of amyloid-beta imaging: a tale of radionuclides and tracer proliferation

(2008) William E Klunk et al.   CURRENT OPINION IN NEUROLOGY

Secondary structure conversions of Alzheimer’s Aβ(1-40) peptide induced by membrane-mimicking detergents

(2008) Anna Wahlström et al.   FEBS Journal

A New Amyloid-Like β-Aggregate with Amyloid Characteristics, Except Fibril Morphology

(2008) Evan S.-H. Chang et al.   JOURNAL OF MOLECULAR BIOLOGY

Potential amyloid plaque-specific peptides for the diagnosis of Alzheimer's disease

(2008) Lionel Larbanoix et al.   NEUROBIOLOGY OF AGING

Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation

(2008) Wolfgang Hoyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice

(2007) Einar M. Sigurdsson et al.   NEUROBIOLOGY OF AGING