A copper–amyloid-β targeted fluorescent chelator as a potential theranostic agent for Alzheimer's disease

A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation

(2016) Yinhui Li et al.   BIOMATERIALS

Specific self-monitoring of metal-associated amyloid-β peptide disaggregation by a fluorescent chelator

(2016) Tao Yang et al.   CHEMICAL COMMUNICATIONS

Multiple Function Fluorescein Probe Performs Metal Chelation, Disaggregation, and Modulation of Aggregated Aβ and Aβ-Cu Complex

(2015) B. Muthuraj et al.   ACS Chemical Neuroscience

Site-selective recognition of peptide phosphorylation by a terbium(iii) complex in aqueous solution

(2015) Xiaohui Wang et al.   CHEMICAL COMMUNICATIONS

Amyloid β Protein and Alzheimer’s Disease: When Computer Simulations Complement Experimental Studies

(2015) Jessica Nasica-Labouze et al.   CHEMICAL REVIEWS

Imaging of β-amyloid plaques by near infrared fluorescent tracers: a new frontier for chemical neuroscience

(2015) Matteo Staderini et al.   CHEMICAL SOCIETY REVIEWS

Small conjugate-based theranostic agents: an encouraging approach for cancer therapy

(2015) Rajesh Kumar et al.   CHEMICAL SOCIETY REVIEWS

Rationally Designed Peptidomimetic Modulators of Aβ Toxicity in Alzheimer's Disease

(2015) K. Rajasekhar et al.   Scientific Reports

The Ongoing Search for Small Molecules to Study Metal-Associated Amyloid-β Species in Alzheimer’s Disease

(2014) Masha G. Savelieff et al.   ACCOUNTS OF CHEMICAL RESEARCH

Electrochemical Immunosensors for Effective Evaluation of Amyloid-Beta Modulators on Oligomeric and Fibrillar Aggregation Processes

(2014) Anthony J. Veloso et al.   ANALYTICAL CHEMISTRY

A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease

(2014) Xueli Zhang et al.   CHEMICAL COMMUNICATIONS

Biological metals and metal-targeting compounds in major neurodegenerative diseases

(2014) Kevin J. Barnham et al.   CHEMICAL SOCIETY REVIEWS

Chiral Metallohelical Complexes Enantioselectively Target Amyloid β for Treating Alzheimer’s Disease

(2014) Meng Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Smart Near-Infrared Fluorescence Probes with Donor–Acceptor Structure for in Vivo Detection of β-Amyloid Deposits

(2014) Mengchao Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bimodal-hybrid heterocyclic amine targeting oxidative pathways and copper mis-regulation in Alzheimer's disease

(2014) Paulina Gonzalez et al.   Metallomics

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biometals and Their Therapeutic Implications in Alzheimer’s Disease

(2014) Scott Ayton et al.   Neurotherapeutics

The benzazole scaffold: a SWAT to combat Alzheimer's disease

(2013) Sabrina Noël et al.   CHEMICAL SOCIETY REVIEWS

Synthesis, conjugation and relaxation studies of gadolinium(iii)-4-benzothiazol-2-yl-phenylamine as a potential brain specific MR contrast agent

(2013) Nisha Saini et al.   DALTON TRANSACTIONS

Role of Metal Ions in the Self-assembly of the Alzheimer’s Amyloid-β Peptide

(2013) Peter Faller et al.   INORGANIC CHEMISTRY

Rational Design of a Structural Framework with Potential Use to Develop Chemical Reagents That Target and Modulate Multiple Facets of Alzheimer’s Disease

(2013) Sanghyun Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design and Synthesis of Curcumin Analogues for in Vivo Fluorescence Imaging and Inhibiting Copper-Induced Cross-Linking of Amyloid Beta Species in Alzheimer’s Disease

(2013) Xueli Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dye-Binding Assays for Evaluation of the Effects of Small Molecule Inhibitors on Amyloid (Aβ) Self-Assembly

(2012) Laramie P. Jameson et al.   ACS Chemical Neuroscience

Bioinorganic Chemistry of Alzheimer’s Disease

(2012) Kasper P. Kepp   CHEMICAL REVIEWS

Metal-associated amyloid-β species in Alzheimer's disease

(2012) Amit S Pithadia et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Bifunctional Compounds for Controlling Metal-Mediated Aggregation of the Aβ42 Peptide

(2012) Anuj K. Sharma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preventing Alzheimer's Disease

(2012) D. J. Selkoe   SCIENCE

Inhibitory action of macrocyclic platiniferous chelators on metal-induced Aβ aggregation

(2012) Xiaohui Wang et al.   Chemical Science

Theranostics: Combining Imaging and Therapy

(2011) Sneha S. Kelkar et al.   BIOCONJUGATE CHEMISTRY

Insight into Amyloid Structure Using Chemical Probes

(2011) Ashley A. Reinke et al.   Chemical Biology & Drug Design

Copper(II) interaction with amyloid-β: Affinity and speciation

(2011) Giuseppe Arena et al.   COORDINATION CHEMISTRY REVIEWS

Cyclam-methylbenzimidazole: a Selective OFF-ON Fluorescent Sensor for Zinc

(2011) Abir El Majzoub et al.   INORGANIC CHEMISTRY

Multifunctional agents for concurrent imaging and therapy in cardiovascular disease

(2010) Jason R. McCarthy   ADVANCED DRUG DELIVERY REVIEWS

Neurotherapeutic applications of nanoparticles in Alzheimer's disease

(2010) Jasjeet Kaur Sahni et al.   JOURNAL OF CONTROLLED RELEASE

Design of small molecules that target metal-A  species and regulate metal-induced A  aggregation and neurotoxicity

(2010) J.-S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease drug development and the problem of the blood-brain barrier

(2009) William M. Pardridge   Alzheimers & Dementia

Effects of Cyclen and Cyclam on Zinc(II)- and Copper(II)-Induced Amyloid β-Peptide Aggregation and Neurotoxicity

(2009) Tingting Chen et al.   INORGANIC CHEMISTRY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Coumarin-Derived Cu2+-Selective Fluorescence Sensor: Synthesis, Mechanisms, and Applications in Living Cells

(2009) Hyo Sung Jung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alzheimer's disease

(2009) Lennart Mucke   NATURE

Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide

(2008) Peter Faller et al.   DALTON TRANSACTIONS

Sequestration of Copper from β-Amyloid Promotes Selective Lysis by Cyclen-Hybrid Cleavage Agents

(2008) Wei-hui Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantification of the Binding Constant of Copper(II) to the Amyloid-Beta Peptide

(2008) Lanying Q. Hatcher et al.   JOURNAL OF PHYSICAL CHEMISTRY B