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Title
Addressing Blood–Brain Barrier Impairment in Alzheimer’s Disease
Authors
Keywords
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Journal
Biomedicines
Volume 10, Issue 4, Pages 742
Publisher
MDPI AG
Online
2022-03-23
DOI
10.3390/biomedicines10040742
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Note: Only part of the references are listed.- Impact of Tau on Neurovascular Pathology in Alzheimer's Disease
- (2021) Elisa Canepa et al. Frontiers in Neurology
- Water exchange rate across the blood‐brain barrier is associated with CSF amyloid‐β 42 in healthy older adults
- (2021) Brian T. Gold et al. Alzheimers & Dementia
- Control of hippocampal pKr‐2 expression reduces neurotoxic symptoms in 5XFAD mice
- (2021) Sehwan Kim et al. BRITISH JOURNAL OF PHARMACOLOGY
- Blood–Brain Barrier and Neurodegenerative Diseases—Modeling with iPSC-Derived Brain Cells
- (2021) Ying-Chieh Wu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Waste Clearance in the Brain
- (2021) Jasleen Kaur et al. Frontiers in Neuroanatomy
- Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease
- (2021) Stefania Forner et al. Scientific Data
- Multifaceted roles of pericytes in central nervous system homeostasis and disease
- (2020) Zhitong Zheng et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Loss of Capillary Pericytes and the Blood‐Brain Barrier in White Matter in Post‐Stroke and Vascular Dementias and Alzheimer’s Disease
- (2020) Ren Ding et al. BRAIN PATHOLOGY
- Angiogenesis and Blood-Brain Barrier Permeability in Vascular Remodeling after Stroke
- (2020) Yi Yang et al. Current Neuropharmacology
- A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy
- (2020) Xavier Taylor et al. Journal of Neuroinflammation
- Blood-Brain Barrier: More Contributor to Disruption of Central Nervous System Homeostasis Than Victim in Neurological Disorders
- (2020) Minjia Xiao et al. Frontiers in Neuroscience
- Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders
- (2020) Jeffrey J. Lochhead et al. Frontiers in Physiology
- Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease
- (2020) Chia‐Chen Liu et al. Alzheimers & Dementia
- Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity
- (2020) Patrick T Ronaldson et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Associations between vascular function and tau PET are associated with global cognition and amyloid
- (2020) Daniel Albrecht et al. JOURNAL OF NEUROSCIENCE
- Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer’s disease
- (2020) Shun-Fat Lau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Imaging the role of blood–brain barrier disruption in normal cognitive ageing
- (2020) Inge C. M. Verheggen et al. GeroScience
- Donepezil provides neuroprotective effects against brain injury and Alzheimer's pathology under conditions of cardiac ischemia/reperfusion injury
- (2020) Benjamin Ongnok et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
- (2019) Daniel A. Nation et al. NATURE MEDICINE
- Blood-Brain Barrier Leakage and Microvascular Lesions in Cerebral Amyloid Angiopathy
- (2019) Whitney M. Freeze et al. STROKE
- Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer’s Disease Model
- (2019) Mario Merlini et al. NEURON
- Neutralization of interleukin-9 ameliorates experimental stroke by repairing the blood–brain barrier via down-regulation of astrocyte-derived vascular endothelial growth factor-A
- (2019) Sha Tan et al. FASEB JOURNAL
- Selective loss of cortical endothelial tight junction proteins during Alzheimer’s disease progression
- (2019) Yu Yamazaki et al. BRAIN
- Multi-faceted therapeutic strategy for treatment of Alzheimer's disease by concurrent administration of etodolac and α-tocopherol
- (2019) Khaled H. Elfakhri et al. NEUROBIOLOGY OF DISEASE
- Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer’s disease by remodeling peri-plaque astrocyte structure
- (2019) Alex J. Smith et al. Acta Neuropathologica Communications
- Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies
- (2019) Yu Yamazaki et al. Nature Reviews Neurology
- Deciphering the Link Between Hyperhomocysteinemia and Ceramide Metabolism in Alzheimer-Type Neurodegeneration
- (2019) Hervé Le Stunff et al. Frontiers in Neurology
- The anatomy and immunology of vasculature in the central nervous system
- (2019) Panagiotis Mastorakos et al. Science Immunology
- Alzheimer’s/Vascular Spectrum Dementia: Classification in Addition to Diagnosis
- (2019) Sheina Emrani et al. JOURNAL OF ALZHEIMERS DISEASE
- Vascular Risk Factors and Alzheimer’s Disease: Blood-Brain Barrier Disruption, Metabolic Syndromes, and Molecular Links
- (2019) Jin-Ting He et al. JOURNAL OF ALZHEIMERS DISEASE
- Environmental lead exposure aggravates the progression of Alzheimer's disease in mice by targeting on blood brain barrier
- (2019) Sai Wu et al. TOXICOLOGY LETTERS
- Dual microglia effects on blood brain barrier permeability induced by systemic inflammation
- (2019) Koichiro Haruwaka et al. Nature Communications
- Amyloid-beta 1-40 is associated with alterations in NG2+ pericyte population ex vivo and in vitro
- (2018) Nina Schultz et al. AGING CELL
- Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment
- (2018) Candice E. Van Skike et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Person-specific contribution of neuropathologies to cognitive loss in old age
- (2018) Patricia A. Boyle et al. ANNALS OF NEUROLOGY
- The Blood Brain Barrier and its Role in Alzheimer's Therapy: An Overview
- (2018) Satya Lavanya Jakki et al. CURRENT DRUG TARGETS
- Blood-brain barrier and its function during inflammation and autoimmunity
- (2018) Sandip Ashok Sonar et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury
- (2018) Justin R. Piro et al. Journal of Neuroinflammation
- Blood-Brain Barrier Disruption and Perivascular Beta-Amyloid Accumulation in the Brain of Aged Rats with Spontaneous Hypertension: Evaluation with Dynamic Contrast-Enhanced Magnetic Resonance Imaging
- (2018) Yu Wang et al. KOREAN JOURNAL OF RADIOLOGY
- Blood-brain barrier (BBB) and the complement landscape
- (2018) Jessy J. Alexander MOLECULAR IMMUNOLOGY
- Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer’s disease
- (2018) Rachel E. Bennett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increased Iron Levels and Decreased Tissue Integrity in Hippocampus of Alzheimer's Disease Detected in vivo with Magnetic Resonance Imaging
- (2018) Erika P. Raven et al. JOURNAL OF ALZHEIMERS DISEASE
- Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
- (2018) Tyler J. Bussian et al. NATURE
- The role of brain vasculature in neurodegenerative disorders
- (2018) Melanie D. Sweeney et al. NATURE NEUROSCIENCE
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- (2018) Ivan Presta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Jae Kyu Ryu et al. NATURE IMMUNOLOGY
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- (2017) Takashi Tarumi et al. JOURNAL OF NEUROCHEMISTRY
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- (2017) Zhiyou Cai et al. JOURNAL OF NEUROLOGY
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- (2017) J. Duncombe et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
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- (2017) E. F. Goodall et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
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- (2017) Kasey E. Moritz et al. Scientific Reports
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- (2017) Diana L Castillo-Carranza et al. Aging and Disease
- Why Do So Many Drugs for Alzheimer's Disease Fail in Development? Time for New Methods and New Practices?
- (2017) Robert E. Becker et al. JOURNAL OF ALZHEIMERS DISEASE
- Caffeine Suppresses Amyloid-β Levels in Plasma and Brain of Alzheimer's Disease Transgenic Mice
- (2017) Chuanhai Cao et al. JOURNAL OF ALZHEIMERS DISEASE
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- (2017) Sara Brilha et al. Scientific Reports
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- (2016) Huang Huang et al. AGE
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- (2016) Franciska Erdő et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson's disease
- (2016) Naveed Malek et al. MOVEMENT DISORDERS
- Pericytes of the neurovascular unit: key functions and signaling pathways
- (2016) Melanie D Sweeney et al. NATURE NEUROSCIENCE
- Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology
- (2015) Janelle Drouin-Ouellet et al. ANNALS OF NEUROLOGY
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- (2015) Ian F. Kimbrough et al. BRAIN
- Establishment and Dysfunction of the Blood-Brain Barrier
- (2015) Zhen Zhao et al. CELL
- A balanced view of the cerebrospinal fluid composition and functions: Focus on adult humans
- (2015) Reynold Spector et al. EXPERIMENTAL NEUROLOGY
- Brain barriers: Crosstalk between complex tight junctions and adherens junctions
- (2015) Silvia Tietz et al. JOURNAL OF CELL BIOLOGY
- Dexamethasone Potentiates in Vitro Blood-Brain Barrier Recovery after Primary Blast Injury by Glucocorticoid Receptor-Mediated Upregulation of ZO-1 Tight Junction Protein
- (2015) Christopher D Hue et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease
- (2015) Matthew R Halliday et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease
- (2015) Madison T Gray et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases
- (2015) Marjana Brkic et al. MEDIATORS OF INFLAMMATION
- Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease
- (2015) Ilse S. Pienaar et al. NEUROBIOLOGY OF DISEASE
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
- (2015) Axel Montagne et al. NEURON
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- (2015) Owain W. Howell et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
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- (2015) Abhay P. Sagare et al. NEUROSCIENCE LETTERS
- Interleukin-1β induces an inflammatory response and the breakdown of the endothelial cell layer in an improved human THBMEC-based in vitro blood–brain barrier model
- (2014) Josephine Labus et al. JOURNAL OF NEUROSCIENCE METHODS
- Complement and blood–brain barrier integrity
- (2014) Alexander Jacob et al. MOLECULAR IMMUNOLOGY
- Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis
- (2014) Manuel A. Friese et al. Nature Reviews Neurology
- Apolipoprotein E–low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner
- (2014) Lance A. Johnson et al. NEUROBIOLOGY OF DISEASE
- Incidence of cerebral microbleeds in preclinical Alzheimer disease
- (2014) P. A. Yates et al. NEUROLOGY
- Matrix Metalloproteinase-3 Causes Dopaminergic Neuronal Death through Nox1-Regenerated Oxidative Stress
- (2014) Dong-Hee Choi et al. PLoS One
- Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasis
- (2014) Franca Orsini et al. Frontiers in Cellular Neuroscience
- Cell-specific blood-brain barrier regulation in health and disease: a focus on hypoxia
- (2013) S Engelhardt et al. BRITISH JOURNAL OF PHARMACOLOGY
- Glucocorticoids and endothelial cell barrier function
- (2013) Ellaine Salvador et al. CELL AND TISSUE RESEARCH
- Neurovascular abnormalities in humans and mice with Huntington's disease
- (2013) Chien-Yuan Lin et al. EXPERIMENTAL NEUROLOGY
- A Blood-Brain Barrier (BBB) Disrupter Is Also a Potent α-Synuclein (α-syn) Aggregation Inhibitor
- (2013) Ronit Shaltiel-Karyo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Blood-Brain Barrier
- (2013) Felix Dyrna et al. Journal of Neuroimmune Pharmacology
- Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect Aβ aggregation features and cross the blood–brain-barrier: Implications for therapy of Alzheimer disease
- (2013) Laura Bana et al. Nanomedicine-Nanotechnology Biology and Medicine
- Development, maintenance and disruption of the blood-brain barrier
- (2013) Birgit Obermeier et al. NATURE MEDICINE
- The Pathobiology of Vascular Dementia
- (2013) Costantino Iadecola NEURON
- A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice
- (2013) Donal T. Skelly et al. PLoS One
- Pericyte loss influences Alzheimer-like neurodegeneration in mice
- (2013) Abhay P. Sagare et al. Nature Communications
- Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
- (2012) Ethan A. Winkler et al. ACTA NEUROPATHOLOGICA
- Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease
- (2012) Jesse D. Sengillo et al. BRAIN PATHOLOGY
- Impaired blood–brain/spinal cord barrier in ALS patients
- (2012) Svitlana Garbuzova-Davis et al. BRAIN RESEARCH
- Blood-Brain Barrier Integrity and Glial Support: Mechanisms that can be Targeted for Novel Therapeutic Approaches in Stroke
- (2012) Patrick T. Ronaldson et al. CURRENT PHARMACEUTICAL DESIGN
- Death Receptors DR6 and TROY Regulate Brain Vascular Development
- (2012) Stephen J. Tam et al. DEVELOPMENTAL CELL
- A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease
- (2012) Rashid Deane et al. JOURNAL OF CLINICAL INVESTIGATION
- Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
- (2012) Azeb Tadesse Argaw et al. JOURNAL OF CLINICAL INVESTIGATION
- A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling
- (2012) S.-Y. Kook et al. JOURNAL OF NEUROSCIENCE
- Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
- (2012) Robert D. Bell et al. NATURE
- Trajectory of white matter hyperintensity burden preceding mild cognitive impairment
- (2012) L. C. Silbert et al. NEUROLOGY
- Exposure to Lipopolysaccharide and/or Unconjugated Bilirubin Impair the Integrity and Function of Brain Microvascular Endothelial Cells
- (2012) Filipa L. Cardoso et al. PLoS One
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Evolution of the blood-brain barrier in newly forming multiple sclerosis lesions
- (2011) María I. Gaitán et al. ANNALS OF NEUROLOGY
- Systemic inflammation induces axon injury during brain inflammation
- (2011) Beatriz Moreno et al. ANNALS OF NEUROLOGY
- Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy
- (2011) Anna Carrano et al. ANTIOXIDANTS & REDOX SIGNALING
- Apolipoprotein E Regulates the Integrity of Tight Junctions in an Isoform-dependent Manner in anin VitroBlood-Brain Barrier Model
- (2011) Kazuchika Nishitsuji et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophic lateral sclerosis
- (2011) Kazunori Miyazaki et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Alzheimer's disease
- (2011) Clive Ballard et al. LANCET
- Central nervous system pericytes in health and disease
- (2011) Ethan A Winkler et al. NATURE NEUROSCIENCE
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
- (2011) Eric Karran et al. NATURE REVIEWS DRUG DISCOVERY
- Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
- (2011) Berislav V. Zlokovic NATURE REVIEWS NEUROSCIENCE
- The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
- (2011) J. I. Alvarez et al. SCIENCE
- Neuroprotective therapeutics for Alzheimer's disease: progress and prospects
- (2011) Alan M. Palmer TRENDS IN PHARMACOLOGICAL SCIENCES
- The Blood-Brain Barrier: Geriatric Relevance of a Critical Brain-Body Interface
- (2010) Neer Zeevi et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Pericytes are required for blood–brain barrier integrity during embryogenesis
- (2010) Richard Daneman et al. NATURE
- Fibrinogen and β-Amyloid Association Alters Thrombosis and Fibrinolysis: A Possible Contributing Factor to Alzheimer's Disease
- (2010) Marta Cortes-Canteli et al. NEURON
- Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
- (2010) Robert D. Bell et al. NEURON
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structure and function of the blood–brain barrier
- (2009) N. Joan Abbott et al. NEUROBIOLOGY OF DISEASE
- DECREASED mRNA EXPRESSION OF TIGHT JUNCTION PROTEINS IN LUMBAR SPINAL CORDS OF PATIENTS WITH ALS
- (2009) J. S. Henkel et al. NEUROLOGY
- Anatomy and development of the meninges: implications for subdural collections and CSF circulation
- (2009) Julie Mack et al. PEDIATRIC RADIOLOGY
- Wnt/ -catenin signaling is required for CNS, but not non-CNS, angiogenesis
- (2009) R. Daneman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown
- (2009) Azeb Tadesse Argaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction
- (2009) Britta Engelhardt et al. Seminars in Immunopathology
- Anatomy and Imaging of the Normal Meninges
- (2009) Neel Patel et al. SEMINARS IN ULTRASOUND CT AND MRI
- Brain Endothelial Cell-Cell Junctions: How to “Open” the Blood Brain Barrier
- (2008) Svetlana Stamatovic et al. Current Neuropharmacology
- Wnt/β-catenin signaling controls development of the blood–brain barrier
- (2008) Stefan Liebner et al. JOURNAL OF CELL BIOLOGY
- A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain
- (2008) Jae K. Ryu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Perivascular Spaces and the Two Steps to Neuroinflammation
- (2008) Trevor Owens et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Microglial Dysfunction and Defective -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
- (2008) S. E. Hickman et al. JOURNAL OF NEUROSCIENCE
- SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells
- (2008) Robert D. Bell et al. NATURE CELL BIOLOGY
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
- (2008) Berislav V. Zlokovic NEURON
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