- Home
- Publications
- Publication Search
- Publication Details
Title
The role of brain vasculature in neurodegenerative disorders
Authors
Keywords
-
Journal
NATURE NEUROSCIENCE
Volume 21, Issue 10, Pages 1318-1331
Publisher
Springer Nature America, Inc
Online
2018-09-19
DOI
10.1038/s41593-018-0234-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Capillary cerebral amyloid angiopathy in Alzheimer’s disease: association with allocortical/hippocampal microinfarcts and cognitive decline
- (2018) Moritz Hecht et al. ACTA NEUROPATHOLOGICA
- NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
- (2018) Clifford R. Jack et al. Alzheimers & Dementia
- Pericyte degeneration causes white matter dysfunction in the mouse central nervous system
- (2018) Axel Montagne et al. NATURE MEDICINE
- Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
- (2018) Melanie D. Sweeney et al. Nature Reviews Neurology
- Capillary pericytes express α-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection
- (2018) Luis Alarcon-Martinez et al. eLife
- Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals
- (2018) Jennifer S. Rabin et al. JAMA Neurology
- High Prevalence of Cerebral Microbleeds at 7Tesla MRI in Patients with Early Alzheimer's Disease
- (2018) Manon Brundel et al. JOURNAL OF ALZHEIMERS DISEASE
- Cortical and Subcortical Cerebrovascular Resistance Index in Mild Cognitive Impairment and Alzheimer's Disease
- (2018) Daniel A. Nation et al. JOURNAL OF ALZHEIMERS DISEASE
- Multiple Microbleeds are Related to Cerebral Network Disruptions in Patients with Early Alzheimer's Disease
- (2018) Sophie M. Heringa et al. JOURNAL OF ALZHEIMERS DISEASE
- A molecular atlas of cell types and zonation in the brain vasculature
- (2018) Michael Vanlandewijck et al. NATURE
- A Cross-Validation of FDG- and Amyloid-PET Biomarkers in Mild Cognitive Impairment for the Risk Prediction to Dementia due to Alzheimer’s Disease in a Clinical Setting
- (2017) Leonardo Iaccarino et al. JOURNAL OF ALZHEIMERS DISEASE
- Reduced Cerebral Blood Flow in Mild Cognitive Impairment Assessed Using Phase-Contrast MRI
- (2017) Reyes García de Eulate et al. JOURNAL OF ALZHEIMERS DISEASE
- Structural and physiological neurovascular changes in idiopathic Parkinson’s disease and its clinical phenotypes
- (2017) Sarah Al-Bachari et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Arterial spin labelling detects posterior cortical hypoperfusion in non-demented patients with Parkinson’s disease
- (2017) Zoe Joanna Syrimi et al. JOURNAL OF NEURAL TRANSMISSION
- Subtle blood-brain barrier leakage rate and spatial extent: Considerations for dynamic contrast-enhanced MRI
- (2017) Harm J. van de Haar et al. MEDICAL PHYSICS
- Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow
- (2017) Thomas A Longden et al. NATURE NEUROSCIENCE
- Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain
- (2017) Kassandra Kisler et al. NATURE NEUROSCIENCE
- Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
- (2017) Kassandra Kisler et al. NATURE REVIEWS NEUROSCIENCE
- The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
- (2017) Costantino Iadecola NEURON
- Mechanisms Mediating Functional Hyperemia in the Brain
- (2017) Amy R. Nippert et al. NEUROSCIENTIST
- Small Molecule PET Tracers for Transporter Imaging
- (2017) Michael R. Kilbourn SEMINARS IN NUCLEAR MEDICINE
- Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling
- (2017) Angeliki Maria Nikolakopoulou et al. PLoS One
- Blood-Brain Glucose Transfer in Alzheimer’s disease: Effect of GLP-1 Analog Treatment
- (2017) Michael Gejl et al. Scientific Reports
- Brain imaging of neurovascular dysfunction in Alzheimer’s disease
- (2016) Axel Montagne et al. ACTA NEUROPATHOLOGICA
- Cortical Perfusion Alteration in Normal-Appearing Gray Matter Is Most Sensitive to Disease Progression in Relapsing-Remitting Multiple Sclerosis
- (2016) S.- P. Hojjat et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease
- (2016) Amy R. Nelson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Cerebral microbleeds as a biomarker in Alzheimer's disease? A review in the field
- (2016) Sara Shams et al. Biomarkers in Medicine
- The Utility of Cerebral Blood Flow as a Biomarker of Preclinical Alzheimer’s Disease
- (2016) Chelsea C. Hays et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Interaction between cerebrovascular disease and Alzheimer pathology
- (2016) Satoshi Saito et al. CURRENT OPINION IN PSYCHIATRY
- Cerebral blood flow modulation insufficiency in brain networks in multiple sclerosis: A hypercapnia MRI study
- (2016) Olga Marshall et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cerebral microbleeds in early Alzheimer’s disease
- (2016) T. Poliakova et al. JOURNAL OF NEUROLOGY
- Granular Layer Neurons Control Cerebellar Neurovascular Coupling Through an NMDA Receptor/NO-Dependent System
- (2016) Lisa Mapelli et al. JOURNAL OF NEUROSCIENCE
- Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina
- (2016) Kyle R. Biesecker et al. JOURNAL OF NEUROSCIENCE
- Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study
- (2016) Zoe Arvanitakis et al. LANCET NEUROLOGY
- Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles
- (2016) Anusha Mishra et al. NATURE NEUROSCIENCE
- Pericytes of the neurovascular unit: key functions and signaling pathways
- (2016) Melanie D Sweeney et al. NATURE NEUROSCIENCE
- The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice
- (2016) Mafalda Cacciottolo et al. NEUROBIOLOGY OF AGING
- Neurovascular unit impairment in early Alzheimer's disease measured with magnetic resonance imaging
- (2016) Harm J. van de Haar et al. NEUROBIOLOGY OF AGING
- Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation
- (2016) Helen Shinru Wei et al. NEURON
- Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease
- (2016) Harm J. van de Haar et al. RADIOLOGY
- Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier
- (2016) H. Gerwien et al. Science Translational Medicine
- Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
- (2016) Y. Iturria-Medina et al. Nature Communications
- Cell type specificity of neurovascular coupling in cerebral cortex
- (2016) Hana Uhlirova et al. eLife
- Reduced cerebrovascular reactivity in young adults carrying the APOE ε4 allele
- (2015) Sana Suri et al. Alzheimers & Dementia
- Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology
- (2015) Janelle Drouin-Ouellet et al. ANNALS OF NEUROLOGY
- Establishment and Dysfunction of the Blood-Brain Barrier
- (2015) Zhen Zhao et al. CELL
- Arterial spin labeling imaging reveals widespread and Aβ-independent reductions in cerebral blood flow in elderly apolipoprotein epsilon-4 carriers
- (2015) Lars Michels et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cerebrospinal Fluid Biomarkers of Neurovascular Dysfunction in Mild Dementia and Alzheimer'S Disease
- (2015) Melanie D Sweeney et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Apolipoprotein E, Carbon Dioxide Vasoreactivity, and Cognition in Older Adults: Effect of Hypertension
- (2015) Ihab Hajjar et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration
- (2015) Ethan A Winkler et al. NATURE NEUROSCIENCE
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
- (2015) Axel Montagne et al. NEURON
- Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes
- (2015) Robert A. Hill et al. NEURON
- The prevalence and risk factors of cerebral microbleeds in patients with Parkinson's disease
- (2015) Kazuo Yamashiro et al. PARKINSONISM & RELATED DISORDERS
- Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
- (2015) A. Zeisel et al. SCIENCE
- Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer’s Disease and Mild Cognitive Impairment: MRI and18F-FDG PET Quantitative Analysis Using FreeSurfer
- (2015) Matthieu Bailly et al. Biomed Research International
- Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice
- (2015) David A. Hartmann et al. Neurophotonics
- Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy
- (2015) Laura J Blair et al. Acta Neuropathologica Communications
- Cerebral Microbleeds: Different Prevalence, Topography, and Risk Factors Depending on Dementia Diagnosis—The Karolinska Imaging Dementia Study
- (2014) S. Shams et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- Coupling Mechanism and Significance of the BOLD Signal: A Status Report
- (2014) Elizabeth M.C. Hillman Annual Review of Neuroscience
- Impaired Cerebral Autoregulation and Vasomotor Reactivity in Sporadic Alzheimer’s Disease
- (2014) Aisha Abeelen et al. Current Alzheimer Research
- Characterization of cerebral microbleeds in idiopathic Parkinson's disease
- (2014) J.-H. Kim et al. EUROPEAN JOURNAL OF NEUROLOGY
- Human Apolipoprotein E ε4 Expression Impairs Cerebral Vascularization and Blood—Brain Barrier Function in Mice
- (2014) Wael Alata et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cerebral microbleeds in patients with Parkinson’s disease
- (2014) Jee Hyun Ham et al. JOURNAL OF NEUROLOGY
- Activity of P-Glycoprotein, a -Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease
- (2014) A. K. Deo et al. JOURNAL OF NUCLEAR MEDICINE
- Mfsd2a is critical for the formation and function of the blood–brain barrier
- (2014) Ayal Ben-Zvi et al. NATURE
- Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid
- (2014) Long N. Nguyen et al. NATURE
- Capillary pericytes regulate cerebral blood flow in health and disease
- (2014) Catherine N. Hall et al. NATURE
- Incidence of cerebral microbleeds in preclinical Alzheimer disease
- (2014) P. A. Yates et al. NEUROLOGY
- Age-Dependent Neurovascular Dysfunction and Damage in a Mouse Model of Cerebral Amyloid Angiopathy
- (2014) Laibaik Park et al. STROKE
- Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer’s Coordinating Centre
- (2013) Jon B. Toledo et al. BRAIN
- Purinergic control of vascular tone in the retina
- (2013) Joanna Kur et al. JOURNAL OF PHYSIOLOGY-LONDON
- Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
- (2013) Clifford R Jack et al. LANCET NEUROLOGY
- Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
- (2013) Joanna M Wardlaw et al. LANCET NEUROLOGY
- The cortical angiome: an interconnected vascular network with noncolumnar patterns of blood flow
- (2013) Pablo Blinder et al. NATURE NEUROSCIENCE
- The Pathobiology of Vascular Dementia
- (2013) Costantino Iadecola NEURON
- Pericyte loss influences Alzheimer-like neurodegeneration in mice
- (2013) Abhay P. Sagare et al. Nature Communications
- Abnormal blood–brain barrier permeability in normal appearing white matter in multiple sclerosis investigated by MRI
- (2013) S.P. Cramer et al. NeuroImage-Clinical
- Prevalence and Topography of Small Hypointense Foci Suggesting Microbleeds on 3T Susceptibility-Weighted Imaging in Various Types of Dementia
- (2012) H. Uetani et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- Widespread cerebral haemodynamics disturbances occur early in amyotrophic lateral sclerosis
- (2012) Matthew J. Murphy et al. Amyotrophic Lateral Sclerosis
- Functional magnetic resonance imaging detection of vascular reactivity in cerebral amyloid angiopathy
- (2012) Andrew Dumas et al. ANNALS OF NEUROLOGY
- Quantification of Perfusion and Permeability in Multiple Sclerosis
- (2012) Michael Ingrisch et al. INVESTIGATIVE RADIOLOGY
- Effect of Mild Cognitive Impairment and APOE Genotype on Resting Cerebral Blood Flow and its Association with Cognition
- (2012) Christina E Wierenga et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease
- (2012) Rashid Deane et al. JOURNAL OF CLINICAL INVESTIGATION
- Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
- (2012) Robert D. Bell et al. NATURE
- Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents
- (2012) Lisa Mosconi et al. NEUROBIOLOGY OF AGING
- Ultra-sensitive molecular MRI of cerebrovascular cell activation enables early detection of chronic central nervous system disorders
- (2012) Axel Montagne et al. NEUROIMAGE
- Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
- (2012) Randall J. Bateman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Iron Accumulation in Deep Cortical Layers Accounts for MRI Signal Abnormalities in ALS: Correlating 7 Tesla MRI and Pathology
- (2012) Justin Y. Kwan et al. PLoS One
- Posterior Cingulate Glucose Metabolism, Hippocampal Glucose Metabolism, and Hippocampal Volume in Cognitively Normal, Late-Middle-Aged Persons at 3 Levels of Genetic Risk for Alzheimer Disease
- (2012) Hillary D. Protas et al. JAMA Neurology
- Evolution of the blood-brain barrier in newly forming multiple sclerosis lesions
- (2011) María I. Gaitán et al. ANNALS OF NEUROLOGY
- Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson's disease
- (2011) T. R. Melzer et al. BRAIN
- Blood–brain barrier P-glycoprotein function in Alzheimer's disease
- (2011) Daniëlle M. E. van Assema et al. BRAIN
- Perfusion abnormalities in mild cognitive impairment and mild dementia in Alzheimer’s disease measured by pulsed arterial spin labeling MRI
- (2011) Panagiotis Alexopoulos et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Central nervous system pericytes in health and disease
- (2011) Ethan A Winkler et al. NATURE NEUROSCIENCE
- Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
- (2011) Berislav V. Zlokovic NATURE REVIEWS NEUROSCIENCE
- Complex relationships between cerebral blood flow and brain atrophy in early Huntington's disease
- (2011) J. Jean Chen et al. NEUROIMAGE
- Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease
- (2011) Y. Chen et al. NEUROLOGY
- APOE ε4 Genotype and Longitudinal Changes in Cerebral Blood Flow in Normal Aging
- (2010) Madhav Thambisetty et al. ARCHIVES OF NEUROLOGY
- Quantitative measurement of blood-brain barrier permeability in human using dynamic contrast-enhanced MRI with fast T1 mapping
- (2010) Saeid Taheri et al. MAGNETIC RESONANCE IN MEDICINE
- Pericytes regulate the blood–brain barrier
- (2010) Annika Armulik et al. NATURE
- Pericytes are required for blood–brain barrier integrity during embryogenesis
- (2010) Richard Daneman et al. NATURE
- Forebrain-dominant deficit in cerebrovascular reactivity in Alzheimer's disease
- (2010) Uma S. Yezhuvath et al. NEUROBIOLOGY OF AGING
- Distinct cerebral perfusion patterns in FTLD and AD
- (2010) W. T. Hu et al. NEUROLOGY
- Gray matter perfusion correlates with disease severity in ALS
- (2010) R. R. Rule et al. NEUROLOGY
- Comparing predictors of conversion and decline in mild cognitive impairment
- (2010) S. M. Landau et al. NEUROLOGY
- Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
- (2010) Robert D. Bell et al. NEURON
- Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain
- (2010) F. Fernandez-Klett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Simultaneous Measurement of Arterial Transit Time, Arterial Blood Volume, and Cerebral Blood Flow Using Arterial Spin-Labeling in Patients with Alzheimer Disease
- (2009) T. Yoshiura et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- Age-Related Vascular Pathology in Transgenic Mice Expressing Presenilin 1-Associated Familial Alzheimer's Disease Mutations
- (2009) Miguel A. Gama Sosa et al. AMERICAN JOURNAL OF PATHOLOGY
- FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer’s disease
- (2009) Lisa Mosconi et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Muscarinic Receptor Knockout Mice Confirm Involvement of M3 Receptor in Endothelium-dependent Vasodilatation in Mouse Arteries
- (2009) Jean-Louis Bény et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI
- (2009) Susan M. Landau et al. NEUROBIOLOGY OF AGING
- Mild Cognitive Impairment and Alzheimer Disease: Patterns of Altered Cerebral Blood Flow at MR Imaging
- (2009) Weiying Dai et al. RADIOLOGY
- Wnt/β-catenin signaling controls development of the blood–brain barrier
- (2008) Stefan Liebner et al. JOURNAL OF CELL BIOLOGY
- Multicenter Standardized 18F-FDG PET Diagnosis of Mild Cognitive Impairment, Alzheimer's Disease, and Other Dementias
- (2008) L. Mosconi et al. JOURNAL OF NUCLEAR MEDICINE
- Prevalence and risk factors of cerebral microbleeds: The Rotterdam Scan Study
- (2008) M. W. Vernooij et al. NEUROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now