A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

At the extreme end of the psychoneuroimmunological spectrum: Delirium as a maladaptive sickness behaviour response

(2012) Colm Cunningham et al.   BRAIN BEHAVIOR AND IMMUNITY

Simvastatin and atorvastatin attenuate VCAM-1 and uPAR expression on human endothelial cells and platelet surface expression of CD40 ligand

(2012) Ksenija Stach et al.   Cardiology Journal

Microglia and neurodegeneration: The role of systemic inflammation

(2012) Colm Cunningham   GLIA

Prior Pathology in the Basal Forebrain Cholinergic System Predisposes to Inflammation-Induced Working Memory Deficits: Reconciling Inflammatory and Cholinergic Hypotheses of Delirium

(2012) R. H. Field et al.   JOURNAL OF NEUROSCIENCE

Neural circuitry engaged by prostaglandins during the sickness syndrome

(2012) Clifford B Saper et al.   NATURE NEUROSCIENCE

Novel cross-talk within the IKK family controls innate immunity

(2011) Kristopher Clark et al.   BIOCHEMICAL JOURNAL

Endothelial progenitor cell-dependent angiogenesis requires localization of the full-length form of uPAR in caveolae

(2011) F. Margheri et al.   BLOOD

Altered hippocampal synaptic transmission in transgenic mice with astrocyte-targeted enhanced CCL2 expression

(2011) Thomas E. Nelson et al.   BRAIN BEHAVIOR AND IMMUNITY

Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system

(2011) William Rostène et al.   JOURNAL OF NEUROCHEMISTRY

Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6

(2011) Carol L Murray et al.   Journal of Neuroinflammation

Peripheral Nerve Injury Alters Blood-Spinal Cord Barrier Functional and Molecular Integrity through a Selective Inflammatory Pathway

(2011) S. Echeverry et al.   JOURNAL OF NEUROSCIENCE

CEREBROSPINAL FLUID INTERLEUKIN-8 LEVELS ARE HIGHER IN PEOPLE WITH HIP FRACTURE WITH PERIOPERATIVE DELIRIUM THAN IN CONTROLS

(2011) Alasdair M.J. MacLullich et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Proinflammatory cytokines, sickness behavior, and Alzheimer disease

(2011) C. Holmes et al.   NEUROLOGY

Role of interleukin-1β in postoperative cognitive dysfunction

(2010) Mario Cibelli et al.   ANNALS OF NEUROLOGY

A Meta-Analysis of Cytokines in Alzheimer's Disease

(2010) Walter Swardfager et al.   BIOLOGICAL PSYCHIATRY

Sickness behaviour is induced by a peripheral CXC-chemokine also expressed in Multiple Sclerosis and EAE

(2010) Sandra J. Campbell et al.   BRAIN BEHAVIOR AND IMMUNITY

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNα/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration

(2010) Robert Field et al.   BRAIN BEHAVIOR AND IMMUNITY

Immune modulation of learning, memory, neural plasticity and neurogenesis

(2010) Raz Yirmiya et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation

(2010) Martina M. Hughes et al.   GLIA

Chemokine CCL2 modulation of neuronal excitability and synaptic transmission in rat hippocampal slices

(2010) Yan Zhou et al.   JOURNAL OF NEUROCHEMISTRY

The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases

(2010) Grégory Conductier et al.   JOURNAL OF NEUROIMMUNOLOGY

Synaptic Correlates of Increased Cognitive Vulnerability with Aging: Peripheral Immune Challenge and Aging Interact to Disrupt Theta-Burst Late-Phase Long-Term Potentiation in Hippocampal Area CA1

(2010) T. R. Chapman et al.   JOURNAL OF NEUROSCIENCE

A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma

(2010) Lih-Chyang Chen et al.   MODERN PATHOLOGY

Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium

(2010) Carol Murray et al.   NEUROBIOLOGY OF AGING

Tumor necrosis factor-  triggers a cytokine cascade yielding postoperative cognitive decline

(2010) N. Terrando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differences in the relative involvement of peripherally released interleukin (IL)-6, brain IL-1β and prostanoids in mediating lipopolysaccharide-induced fever and sickness behavior

(2010) Lois M. Harden et al.   PSYCHONEUROENDOCRINOLOGY

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

A Meta-Analysis of Cytokines in Major Depression

(2009) Yekta Dowlati et al.   BIOLOGICAL PSYCHIATRY

Sustained hippocampal IL-1β overexpression impairs contextual and spatial memory in transgenic mice

(2009) Amy M. Hein et al.   BRAIN BEHAVIOR AND IMMUNITY

The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1

(2009) J.L. Teeling et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglia and the urokinase plasminogen activator receptor/uPA system in innate brain inflammation

(2009) Orla Cunningham et al.   GLIA

Use of the Pharmacological Inhibitor BX795 to Study the Regulation and Physiological Roles of TBK1 and IκB Kinase ϵ

(2009) Kristopher Clark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic inflammation and disease progression in Alzheimer disease

(2009) C. Holmes et al.   NEUROLOGY

Interleukin-6 Covaries Inversely with Hippocampal Grey Matter Volume in Middle-Aged Adults

(2008) Anna L. Marsland et al.   BIOLOGICAL PSYCHIATRY

Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease

(2008) Colm Cunningham et al.   BIOLOGICAL PSYCHIATRY

Malaise in the water maze: Untangling the effects of LPS and IL-1β on learning and memory

(2008) Colm Cunningham et al.   BRAIN BEHAVIOR AND IMMUNITY

The Role of Interleukin-6 in Lipopolysaccharide-Induced Fever by Mechanisms Independent of Prostaglandin E2

(2008) Camilla Nilsberth et al.   ENDOCRINOLOGY

The chemokine CCL2 activates p38 mitogen-activated protein kinase pathway in cultured rat hippocampal cells

(2008) Jungsook Cho et al.   JOURNAL OF NEUROIMMUNOLOGY

Time-Course of Cytokines During Delirium in Elderly Patients with Hip Fractures

(2008) Barbara C. Van Munster et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

MyD88 signaling in brain endothelial cells is essential for the neuronal activity and glucocorticoid release during systemic inflammation

(2008) D Gosselin et al.   MOLECULAR PSYCHIATRY

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Primer: inflammasomes and interleukin 1β in inflammatory disorders

(2008) Leigh D Church et al.   Nature clinical practice. Rheumatology

Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system

(2007) Jing Chen et al.   BRAIN BEHAVIOR AND IMMUNITY

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE