Blood-Brain Barrier: More Contributor to Disruption of Central Nervous System Homeostasis Than Victim in Neurological Disorders

Cancer Risk for Fingolimod, Natalizumab, and Rituximab in MS Patients

(2020) Peter Alping et al.   ANNALS OF NEUROLOGY

Ketone Bodies Promote Amyloid-β1–40 Clearance in a Human in Vitro Blood–Brain Barrier Model

(2020) Romain Versele et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification

(2020) Lucia V. Schottlaender et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ozanimod: First Approval

(2020) Yvette N. Lamb   DRUGS

Therapeutic drugs modulate ATP-Binding cassette transporter-mediated transport of amyloid beta(1–42) in brain microvascular endothelial cells

(2020) Maryam H. Shubbar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier

(2020) M. H. Sheikh et al.   Journal of Neuroinflammation

Risk factor for Alzheimer’s disease breaks the blood–brain barrier

(2020) Makoto Ishii et al.   NATURE

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

(2020) Axel Montagne et al.   NATURE

Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles

(2020) Julien Saint-Pol et al.   Cells

Which is the best PML risk stratification strategy in natalizumab-treated patients affected by multiple sclerosis?

(2020) Carla Prezioso et al.   Multiple Sclerosis and Related Disorders

Vascular dysfunction—The disregarded partner of Alzheimer's disease

(2019) Melanie D. Sweeney et al.   Alzheimers & Dementia

New insights into GluT1 mechanics during glucose transfer

(2019) Tatiana Galochkina et al.   Scientific Reports

Significance and Mechanisms of P-glycoprotein in Central Nervous System Diseases

(2019) Liangliang Huang et al.   CURRENT DRUG TARGETS

Propofol improved hypoxia-impaired integrity of blood-brain barrier via modulating the expression and phosphorylation of zonula occludens-1

(2019) Wei Chen et al.   CNS Neuroscience & Therapeutics

Aberrant oligodendroglial–vascular interactions disrupt the blood–brain barrier, triggering CNS inflammation

(2019) Jianqin Niu et al.   NATURE NEUROSCIENCE

The Extent of Human Apolipoprotein A-I Lipidation Strongly Affects the β-Amyloid Efflux Across the Blood-Brain Barrier in vitro

(2019) Roberta Dal Magro et al.   Frontiers in Neuroscience

Metalloproteinases and their tissue inhibitors in Alzheimer’s disease and other neurodegenerative disorders

(2019) Santiago Rivera et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cerebrovascular and Neurological Disorders: Protective Role of NRF2

(2019) Farzane Sivandzade et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxygen-Glucose Deprivation/Reoxygenation Induces Human Brain Microvascular Endothelial Cell Hyperpermeability Via VE-Cadherin Internalization: Roles of RhoA/ROCK2

(2019) Jie Chen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Global brain inflammation in stroke

(2019) Kaibin Shi et al.   LANCET NEUROLOGY

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood–brain barrier

(2019) Kuniyuki Nakamura et al.   JOURNAL OF CELL BIOLOGY

Integrin α5β1 inhibition by ATN-161 reduces neuroinflammation and is neuroprotective in ischemic stroke

(2019) Danielle N Edwards et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Hepcidin and its therapeutic potential in neurodegenerative disorders

(2019) Zhong‐Ming Qian et al.   MEDICINAL RESEARCH REVIEWS

Neurogenesis in Neurodegenerative Diseases: Role of MFG-E8

(2019) Cletus Cheyuo et al.   Frontiers in Neuroscience

Claudin-12 is not required for blood–brain barrier tight junction function

(2019) Mariana Castro Dias et al.   Fluids and Barriers of the CNS

miR-98 reduces endothelial dysfunction by protecting blood–brain barrier (BBB) and improves neurological outcomes in mouse ischemia/reperfusion stroke model

(2019) David L Bernstein et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles

(2019) Sylwia Dabrowska et al.   Journal of Neuroinflammation

Cystatin C improves blood–brain barrier integrity after ischemic brain injury in mice

(2019) Bo Yang et al.   JOURNAL OF NEUROCHEMISTRY

Polarized hemichannel opening of pannexin 1/connexin 43 contributes to dysregulation of transport function in blood-brain barrier endothelial cells

(2019) Masanori Tachikawa et al.   NEUROCHEMISTRY INTERNATIONAL

Simultaneous Blood–Brain Barrier Crossing and Protection for Stroke Treatment Based on Edaravone-Loaded Ceria Nanoparticles

(2018) Qunqun Bao et al.   ACS Nano

Functional morphology of the blood–brain barrier in health and disease

(2018) Stefan Liebner et al.   ACTA NEUROPATHOLOGICA

Impact of aging, Alzheimer's disease and Parkinson's disease on the blood-brain barrier transport of therapeutics

(2018) Yijun Pan et al.   ADVANCED DRUG DELIVERY REVIEWS

Blood-Brain Barrier Dysfunction in Ischemic Stroke: Targeting Tight Junctions and Transporters for Vascular Protection

(2018) Wazir Abdullahi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment

(2018) Candice E. Van Skike et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM

(2018) Steffen E. Storck et al.   BRAIN BEHAVIOR AND IMMUNITY

The role of VE-cadherin in blood-brain barrier integrity under central nervous system pathological conditions

(2018) Wenlu Li et al.   Current Neuropharmacology

ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier

(2018) Yordenca Lamartinière et al.   JOURNAL OF ALZHEIMERS DISEASE

Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption

(2018) Jianping Wang et al.   Journal of Neuroinflammation

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Vitamin D and Its Role in Neonatal Hypoxic-Ischemic Brain Injury

(2018) Lyndsey E. Stessman et al.   Neonatology

Matrix Metalloproteinase-9 Mediates the Deleterious Effects of α2-Antiplasmin on Blood–Brain Barrier Breakdown and Ischemic Brain Injury in Experimental Stroke

(2018) Satish Singh et al.   NEUROSCIENCE

Blood-brain barrier dysfunction and recovery after ischemic stroke

(2018) Xiaoyan Jiang et al.   PROGRESS IN NEUROBIOLOGY

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

(2018) Denzil Furtado et al.   ADVANCED MATERIALS

The glucose transporter type 1 (Glut1) syndromes

(2018) Henner Koch et al.   EPILEPSY & BEHAVIOR

Processing of Endogenous AβPP in Blood-Brain Barrier Endothelial Cells is Modulated by Liver-X Receptor Agonists and Altered Cellular Cholesterol Homeostasis

(2018) Cornelia Schweinzer et al.   JOURNAL OF ALZHEIMERS DISEASE

Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis

(2018) Robert J. Fox et al.   NEW ENGLAND JOURNAL OF MEDICINE

Strategies for brain-targeting liposomal delivery of small hydrophobic molecules in the treatment of neurodegenerative diseases

(2018) Zi-Ying Wang et al.   DRUG DISCOVERY TODAY

Claudin-1 dependent destabilization of the blood-brain barrier in chronic stroke

(2018) Nikola Sladojevic et al.   JOURNAL OF NEUROSCIENCE

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

(2018) Qingyi Ma et al.   Molecular Neurodegeneration

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

Micro- and nanotechnology approaches to improve Parkinson's disease therapy

(2018) Pablo Vicente Torres-Ortega et al.   JOURNAL OF CONTROLLED RELEASE

Vitamin D deficiency increases blood-brain barrier dysfunction after ischemic stroke in male rats

(2018) Iqbal Sayeed et al.   EXPERIMENTAL NEUROLOGY

Alzheimer’s disease: A matter of blood–brain barrier dysfunction?

(2017) Axel Montagne et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vascular pathology in multiple sclerosis: reframing pathogenesis around the blood-brain barrier

(2017) Jonathan I Spencer et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis

(2017) Luanne M. Metz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Use of Statins and Outcomes in Intracerebral Hemorrhage Patients

(2017) Fazeel M. Siddiqui et al.   STROKE

C‐C Chemokine Receptor Type 5 (CCR5)‐Mediated Docking of Transferred Tregs Protects Against Early Blood‐Brain Barrier Disruption After Stroke

(2017) Peiying Li et al.   Journal of the American Heart Association

Testing the Neurovascular Hypothesis of Alzheimer's Disease: LRP-1 Antisense Reduces Blood-brain Barrier Clearance, Increases Brain Levels of Amyloid-β Protein, and Impairs Cognition

(2017) Laura B. Jaeger et al.   JOURNAL OF ALZHEIMERS DISEASE

Apical-to-Basolateral Transport of Amyloid-β Peptides through Blood-Brain Barrier Cells is Mediated by the Receptor for Advanced Glycation End-Products and is Restricted by P-Glycoprotein

(2017) Pietra Candela et al.   JOURNAL OF ALZHEIMERS DISEASE

Angiopoietin-2-induced blood–brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling

(2016) Stefanie Gurnik et al.   ACTA NEUROPATHOLOGICA

Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease

(2016) Amy R. Nelson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

β-asarone and levodopa co-administration increase striatal dopamine level in 6-hydroxydopamine induced rats by modulating P-glycoprotein and tight junction proteins at the blood-brain barrier and promoting levodopa into the brain

(2016) Liping Huang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

α-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function

(2016) Wei-Li Kuan et al.   EXPERIMENTAL NEUROLOGY

Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage

(2016) Minshu Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Low-density lipoprotein receptor-related protein-1 facilitates heme scavenging after intracerebral hemorrhage in mice

(2016) Gaiqing Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage

(2016) Roslyn A. Taylor et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial

(2016) Harold L Atkins et al.   LANCET

Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities

(2016) Richard Macrez et al.   LANCET NEUROLOGY

Glucose Transporters at the Blood-Brain Barrier: Function, Regulation and Gateways for Drug Delivery

(2016) Simon G. Patching   MOLECULAR NEUROBIOLOGY

Pericytes of the neurovascular unit: key functions and signaling pathways

(2016) Melanie D Sweeney et al.   NATURE NEUROSCIENCE

Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke

(2016) Zhongwu Liu et al.   PROGRESS IN NEUROBIOLOGY

Microvascular endothelial cells-derived microvesicles imply in ischemic stroke by modulating astrocyte and blood brain barrier function and cerebral blood flow

(2016) Qunwen Pan et al.   Molecular Brain

Safety and Efficacy of Siponimod (BAF312) in Patients With Relapsing-Remitting Multiple Sclerosis

(2016) Ludwig Kappos et al.   JAMA Neurology

Role of Two Efflux Proteins, ABCB1 and ABCG2 in Blood-Brain Barrier Transport of Bromocriptine in a Murine Model of MPTP-Induced Dopaminergic Degeneration

(2016) Sarah Vautier et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Soluble VCAM-1 impairs human brain endothelial barrier integrity via integrin α-4-transduced outside-in signalling

(2015) Axel Haarmann et al.   ACTA NEUROPATHOLOGICA

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

LSR/angulin-1 is a tricellular tight junction protein involved in blood–brain barrier formation

(2015) Fabien Sohet et al.   JOURNAL OF CELL BIOLOGY

Brain barriers: Crosstalk between complex tight junctions and adherens junctions

(2015) Silvia Tietz et al.   JOURNAL OF CELL BIOLOGY

Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease

(2015) Matthew R Halliday et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease

(2015) Madison T Gray et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants

(2015) Veronica De Rosa et al.   NATURE IMMUNOLOGY

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

(2015) Zhen Zhao et al.   NATURE NEUROSCIENCE

Immune interventions in stroke

(2015) Ying Fu et al.   Nature Reviews Neurology

Targeting secondary injury in intracerebral haemorrhage—perihaematomal oedema

(2015) Sebastian Urday et al.   Nature Reviews Neurology

Increased CSF biomarkers of angiogenesis in Parkinson disease

(2015) Shorena Janelidze et al.   NEUROLOGY

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke

(2015) Christine Weinl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmembrane proteins of the tight junctions at the blood–brain barrier: Structural and functional aspects

(2015) Reiner F. Haseloff et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Normobaric Hyperoxia Slows Blood-Brain Barrier Damage and Expands the Therapeutic Time Window for Tissue-Type Plasminogen Activator Treatment in Cerebral Ischemia

(2015) J. Liang et al.   STROKE

2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment

(2015) William J. Powers et al.   STROKE

The Molecular Constituents of the Blood–Brain Barrier

(2015) Brian Wai Chow et al.   TRENDS IN NEUROSCIENCES

Fingolimod alters inflammatory mediators and vascular permeability in intracerebral hemorrhage

(2015) Yu-Jing Li et al.   Neuroscience Bulletin

P-glycoprotein regulates trafficking of CD8+ T cells to the brain parenchyma

(2014) Gijs Kooij et al.   ACTA NEUROPATHOLOGICA

Role of the Blood–Brain Barrier in Multiple Sclerosis

(2014) Genaro Gabriel Ortiz et al.   ARCHIVES OF MEDICAL RESEARCH

Tight junction dynamics: the role of junctional adhesion molecules (JAMs)

(2014) S. Garrido-Urbani et al.   CELL AND TISSUE RESEARCH

Statins and Neuroprotection: Basic Pharmacology Needed

(2014) W. Gibson Wood et al.   MOLECULAR NEUROBIOLOGY

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

Inhibition of junctional adhesion molecule-A/LFA interaction attenuates leukocyte trafficking and inflammation in brain ischemia/reperfusion injury

(2014) Nikola Sladojevic et al.   NEUROBIOLOGY OF DISEASE

Neuroprotective effect of the chemical chaperone, trehalose in a chronic MPTP-induced Parkinson's disease mouse model

(2014) Sumit Sarkar et al.   NEUROTOXICOLOGY

Neuro-Endocrine Networks Controlling Immune System in Health and Disease

(2014) Claudio Procaccini et al.   Frontiers in Immunology

Oxysterols decrease apical-to-basolateral transport of Aß peptides via an ABCB1-mediated process in an in vitro Blood-brain barrier model constituted of bovine brain capillary endothelial cells

(2013) Julien Saint-Pol et al.   BRAIN RESEARCH

Initial Immunopathogenesis of Multiple Sclerosis: Innate Immune Response

(2013) Norma Y. Hernández-Pedro et al.   Clinical & Developmental Immunology

Effects of celecoxib on hematoma and edema volumes in primary intracerebral hemorrhage: a multicenter randomized controlled trial

(2013) S.-H. Lee et al.   EUROPEAN JOURNAL OF NEUROLOGY

Glutathione metabolism and Parkinson's disease

(2013) Michelle Smeyne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting dysregulation of brain iron homeostasis in Parkinson's disease by iron chelators

(2013) Orly Weinreb et al.   FREE RADICAL BIOLOGY AND MEDICINE

Is MS an inflammatory or primary degenerative disease?

(2013) Jacek Losy   JOURNAL OF NEURAL TRANSMISSION

Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect Aβ aggregation features and cross the blood–brain-barrier: Implications for therapy of Alzheimer disease

(2013) Laura Bana et al.   Nanomedicine-Nanotechnology Biology and Medicine

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

GDNF, NGF and BDNF as therapeutic options for neurodegeneration

(2013) Shelley J. Allen et al.   PHARMACOLOGY & THERAPEUTICS

Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy

(2013) Y. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Minocycline Plus Tissue Plasminogen Activator Combination Therapy After Focal Embolic Stroke in Type 1 Diabetic Rats

(2013) Xiang Fan et al.   STROKE

Pericyte loss influences Alzheimer-like neurodegeneration in mice

(2013) Abhay P. Sagare et al.   Nature Communications

Thrombin-Induced Cerebral Hemorrhage: Role of Protease-Activated Receptor-1

(2013) Yingying Cheng et al.   Translational Stroke Research

Fingolimod attenuates ceramide-induced blood–brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes

(2012) Ruben van Doorn et al.   ACTA NEUROPATHOLOGICA

The blood-brain barrier in health and disease

(2012) Richard Daneman   ANNALS OF NEUROLOGY

Matrix Metalloproteinases in Human Spontaneous Intracerebral Hemorrhage: An Update

(2012) M. Florczak-Rzepka et al.   CEREBROVASCULAR DISEASES

Vitamin D Deficiency Exacerbates Experimental Stroke Injury and Dysregulates Ischemia-Induced Inflammation in Adult Rats

(2012) Robyn Balden et al.   ENDOCRINOLOGY

Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage

(2012) William B. Rolland et al.   EXPERIMENTAL NEUROLOGY

Junctional Protein Regulation by Sphingosine Kinase 2 Contributes to Blood–Brain Barrier Protection in Hypoxic Preconditioning-Induced Cerebral Ischemic Tolerance

(2012) Bradley K Wacker et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Deletion of Astroglial Connexins Weakens the Blood–Brain Barrier

(2012) Pascal Ezan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease

(2012) Azeb Tadesse Argaw et al.   JOURNAL OF CLINICAL INVESTIGATION

A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling

(2012) S.-Y. Kook et al.   JOURNAL OF NEUROSCIENCE

Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood-Brain Barrier Damage in Early Ischemic Stroke Stage

(2012) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Apolipoprotéine E et intégrité de la barrière hémato-encéphalique

(2012) Fabien Gosselet   M S-MEDECINE SCIENCES

Relocalization of Junctional Adhesion Molecule A during Inflammatory Stimulation of Brain Endothelial Cells

(2012) S. M. Stamatovic et al.   MOLECULAR AND CELLULAR BIOLOGY

The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders

(2012) Koichi Wakabayashi et al.   MOLECULAR NEUROBIOLOGY

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

(2012) Robert D. Bell et al.   NATURE

Blood-brain barrier, reperfusion injury, and hemorrhagic transformation in acute ischemic stroke

(2012) R. Khatri et al.   NEUROLOGY

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation

(2012) Dimitrios Davalos et al.   Nature Communications

The Molecular Mechanisms that Promote Edema After Intracerebral Hemorrhage

(2012) Daniel Bodmer et al.   Translational Stroke Research

Claudin-1 induced sealing of blood–brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis

(2011) Friederike Pfeiffer et al.   ACTA NEUROPATHOLOGICA

Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

(2011) Anna Carrano et al.   ANTIOXIDANTS & REDOX SIGNALING

Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on  4 integrin

(2011) I. Ifergan et al.   BRAIN

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells

(2011) Muhammad Aslam et al.   CYTOKINE

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke

(2011) Kim M. Baeten et al.   Developmental Neurobiology

Specific Role of Tight Junction Proteins Claudin-5, Occludin, and ZO-1 of the Blood–Brain Barrier in a Focal Cerebral Ischemic Insult

(2011) Haixia Jiao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Apolipoprotein E in Alzheimer's disease and other neurological disorders

(2011) Philip B Verghese et al.   LANCET NEUROLOGY

Occludin: One Protein, Many Forms

(2011) P. M. Cummins   MOLECULAR AND CELLULAR BIOLOGY

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Central nervous system pericytes in health and disease

(2011) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Prospects of Statins in Parkinson Disease

(2011) Avik Roy et al.   NEUROSCIENTIST

Amyloid Triggers Extensive Cerebral Angiogenesis Causing Blood Brain Barrier Permeability and Hypervascularity in Alzheimer's Disease

(2011) Kaan E. Biron et al.   PLoS One

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

Functional expression of SGLTs in rat brain

(2010) Amy S. Yu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Brain Endothelial Cells Produce Amyloid β from Amyloid Precursor Protein 770 and Preferentially Secrete theO-Glycosylated Form

(2010) Shinobu Kitazume et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trafficking of immune cells in the central nervous system

(2010) Emma H. Wilson et al.   JOURNAL OF CLINICAL INVESTIGATION

Brain iron metabolism and its perturbation in neurological diseases

(2010) Robert R. Crichton et al.   JOURNAL OF NEURAL TRANSMISSION

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells

(2010) Richard Daneman et al.   PLoS One

Phosphodiesterase-III Inhibitor Prevents Hemorrhagic Transformation Induced by Focal Cerebral Ischemia in Mice Treated with tPA

(2010) Mitsunori Ishiguro et al.   PLoS One

Natural History of Perihematomal Edema After Intracerebral Hemorrhage Measured by Serial Magnetic Resonance Imaging

(2010) Chitra Venkatasubramanian et al.   STROKE

Loss of astrocyte polarity marks blood–brain barrier impairment during experimental autoimmune encephalomyelitis

(2009) Karen Wolburg-Buchholz et al.   ACTA NEUROPATHOLOGICA

Astrocyte–neuron interactions in neurological disorders

(2009) G. Ricci et al.   JOURNAL OF BIOLOGICAL PHYSICS

The blood-brain barrier in neurodegenerative disease: a rhetorical perspective

(2009) Paul M. Carvey et al.   JOURNAL OF NEUROCHEMISTRY

Molecular mechanisms of microvascular failure in central nervous system injury—synergistic roles of NKCC1 and SUR1/TRPM4

(2009) J. Marc Simard et al.   JOURNAL OF NEUROSURGERY

Intracerebral haemorrhage

(2009) Adnan I Qureshi et al.   LANCET

Wnt/ -catenin signaling is required for CNS, but not non-CNS, angiogenesis

(2009) R. Daneman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells

(2008) Masaru Yamamoto et al.   AMERICAN JOURNAL OF PATHOLOGY

Peripheral cytokines profile in Parkinson’s disease

(2008) M. Reale et al.   BRAIN BEHAVIOR AND IMMUNITY

Tissue Plasminogen Activator (tPA) and Matrix Metalloproteinases in the Pathogenesis of Stroke: Therapeutic Strategies

(2008) Rao Adibhatla et al.   CNS & Neurological Disorders-Drug Targets

Endothelial cell-derived bone morphogenetic proteins regulate glial differentiation of cortical progenitors

(2008) Tetsuya Imura et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Formation of the blood–brain barrier: Wnt signaling seals the deal: Figure 1.

(2008) Paul Polakis   JOURNAL OF CELL BIOLOGY

Role of ATP-binding cassette transporters in brain lipid transport and neurological disease

(2008) Woojin Scott Kim et al.   JOURNAL OF NEUROCHEMISTRY

Systemic Inflammation Alters the Kinetics of Cerebrovascular Tight Junction Disruption after Experimental Stroke in Mice

(2008) B. W. McColl et al.   JOURNAL OF NEUROSCIENCE

A Functional Role for Sodium-Dependent Glucose Transport across the Blood-Brain Barrier during Oxygen Glucose Deprivation

(2008) S. Vemula et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Tight Junction Proteins Claudin-2 and -12 Are Critical for Vitamin D-dependent Ca2+ Absorption between Enterocytes

(2008) Hiroki Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Canonical Wnt Signaling Regulates Organ-Specific Assembly and Differentiation of CNS Vasculature

(2008) J. M. Stenman et al.   SCIENCE