Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases

Platelets Facilitate the Wound-Healing Capability of Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic Reprogramming

(2021) Jennyfer Levoux et al.   Cell Metabolism

Association of mitochondrial DNA copy number with metabolic syndrome and type 2 diabetes in 14,176 individuals

(2021) Federica Fazzini et al.   JOURNAL OF INTERNAL MEDICINE

Schizophrenia-associated dysbindin modulates axonal mitochondrial movement in cooperation with p150glued

(2021) Bo Kyoung Suh et al.   Molecular Brain

Endoplasmic Reticulum Interaction Supports Energy Production and Redox Homeostasis in Mitochondria Released from Astrocytes

(2021) Ji-Hyun Park et al.   Translational Stroke Research

Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery

(2021) Alexander J Sercel et al.   eLife

Synaptosomes: new vesicles for neuronal mitochondrial transplantation

(2021) Pasquale Picone et al.   JOURNAL OF NANOBIOTECHNOLOGY

Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial Connexin 43

(2021) Jia-dan Wang et al.   ACTA PHARMACOLOGICA SINICA

Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth

(2021) Abigail S. Krall et al.   Cell Metabolism

Stem cell‐derived mitochondria transplantation: A promising therapy for mitochondrial encephalomyopathy

(2021) Kaiming Liu et al.   CNS Neuroscience & Therapeutics

Mitochondrial Transfer Improves Cardiomyocyte Bioenergetics and Viability in Male Rats Exposed to Pregestational Diabetes

(2021) Eli J. Louwagie et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

GJA1-20K Enhances Mitochondria Transfer from Astrocytes to Neurons via Cx43-TnTs After Traumatic Brain Injury

(2021) Dabin Ren et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Gene duplications trace mitochondria to the onset of eukaryote complexity

(2021) Fernando D K Tria et al.   Genome Biology and Evolution

Mitochondrial Transfer in Cancer: A Comprehensive Review

(2021) Luca X. Zampieri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transfer of mitochondria and endosomes between cells by gap junction internalization

(2021) Rachael P. Norris   TRAFFIC

Mitochondrial Transplantation Modulates Inflammation and Apoptosis, Alleviating Tendinopathy Both In Vivo and In Vitro

(2021) Ji Min Lee et al.   Antioxidants

Mitochondria transfer from early stages of erythroblasts to their macrophage niche via tunnelling nanotubes

(2021) Chong Yang et al.   BRITISH JOURNAL OF HAEMATOLOGY

Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes

(2021) Clair Crewe et al.   Cell Metabolism

Mechanism of insulin resistance in obesity: a role of ATP

(2021) Jianping Ye   Frontiers of Medicine

Alda-1 treatment promotes the therapeutic effect of mitochondrial transplantation for myocardial ischemia-reperfusion injury

(2021) Xiaolei Sun et al.   Bioactive Materials

Intercellular nanotubes mediate mitochondrial trafficking between cancer and immune cells

(2021) Tanmoy Saha et al.   Nature Nanotechnology

Iron oxide nanoparticles augment the intercellular mitochondrial transfer–mediated therapy

(2021) Ting Huang et al.   Science Advances

Mitochondria Do Not Survive Calcium Overload During Transplantation

(2020) Edoardo Bertero et al.   CIRCULATION RESEARCH

Blood contains circulating cell‐free respiratory competent mitochondria

(2020) Zahra Al Amir Dache et al.   FASEB JOURNAL

Optimizing beta cell function through mesenchymal stromal cell mediated mitochondria transfer

(2020) Chloe L. Rackham et al.   STEM CELLS

Biochemical and structural cues of 3D-printed matrix synergistically direct MSC differentiation for functional sweat gland regeneration

(2020) Bin Yao et al.   Science Advances

In Vivo Tracking of Mesenchymal Stem Cell-Derived Extracellular Vesicles Improving Mitochondrial Function in Renal Ischemia–Reperfusion Injury

(2020) Hongmei Cao et al.   ACS Nano

New horizons in mitochondrial contact site research

(2020) Naama Zung et al.   BIOLOGICAL CHEMISTRY

Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits

(2020) Alexandros K. Kanellopoulos et al.   CELL

Peptides derived from small mitochondrial open reading frames: Genomic, biological, and therapeutic implications

(2020) Brendan Miller et al.   EXPERIMENTAL CELL RESEARCH

TAT‐dextran–mediated mitochondrial transfer enhances recovery from models of reperfusion injury in cultured cardiomyocytes

(2020) Hideki Maeda et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Transfer of healthy fibroblast-derived mitochondria to HeLa ρ0 and SAS ρ0 cells recovers the proliferation capabilities of these cancer cells under conventional culture medium, but increase their sensitivity to cisplatin-induced apoptotic death

(2020) Amaneh Mohammadi Roushandeh et al.   MOLECULAR BIOLOGY REPORTS

Bioenergetics Consequences of Mitochondrial Transplantation in Cardiomyocytes

(2020) Paria Ali Pour et al.   Journal of the American Heart Association

Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature

(2020) Anna Picca et al.   Cells

The essential functions of mitochondrial dynamics in immune cells

(2020) Jia-Huan Xie et al.   Cellular & Molecular Immunology

From Cell Entry to Engraftment of Exogenous Mitochondria

(2020) Daisuke Kami et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial transfer from mesenchymal stem cells improves neuronal metabolism after oxidant injury in vitro: The role of Miro1

(2020) Nancy Tseng et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Autogenous Mitochondria Transplantation for Treatment of Right Heart Failure

(2020) Viktoria Weixler et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Characterization and origins of cell-free mitochondria in healthy murine and human blood

(2020) Olivia R. Stephens et al.   MITOCHONDRION

Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization

(2020) Chaoying Yan et al.   MOLECULAR NEUROBIOLOGY

A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing

(2020) Beverly Y. Mok et al.   NATURE

Interpericyte tunnelling nanotubes regulate neurovascular coupling

(2020) Luis Alarcon-Martinez et al.   NATURE

Mitochondria transfer enhances proliferation, migration, and osteogenic differentiation of bone marrow mesenchymal stem cell and promotes bone defect healing

(2020) Yusi Guo et al.   Stem Cell Research & Therapy

FTY720 Regulates Mitochondria Biogenesis in Dendritic Cells to Prevent Kidney Ischemic Reperfusion Injury

(2020) Thomas V. Rousselle et al.   Frontiers in Immunology

Inter and Intracellular mitochondrial trafficking in health and disease

(2020) Santhanam Shanmughapriya et al.   AGEING RESEARCH REVIEWS

A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

(2020) José A. Nicolás-Ávila et al.   CELL

Challenges in Promoting Mitochondrial Transplantation Therapy

(2020) Yuma Yamada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metformin rescues Parkinson’s disease phenotypes caused by hyperactive mitochondria

(2020) Danielle E. Mor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stable retention of chloramphenicol-resistant mtDNA to rescue metabolically impaired cells

(2020) Emma R. Dawson et al.   Scientific Reports

Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells

(2020) Alexander Tishchenko et al.   Cancers

Mitochondrial Transfer by Human Mesenchymal Stromal Cells Ameliorates Hepatocyte Lipid Load in a Mouse Model of NASH

(2020) Mei-Ju Hsu et al.   Biomedicines

Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids

(2020) Giulia Pinto et al.   BIOCHEMICAL JOURNAL

Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity

(2020) Jonathan R. Brestoff et al.   Cell Metabolism

MSC extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS

(2020) Johnatas Dutra Silva et al.   EUROPEAN RESPIRATORY JOURNAL

Autologous mitochondrial transplantation for cardiogenic shock in pediatric patients following ischemia-reperfusion injury

(2020) Alvise Guariento et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Small-molecule inhibitors of human mitochondrial DNA transcription

(2020) Nina A. Bonekamp et al.   NATURE

Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates

(2020) Alexander N. Patananan et al.   Cell Reports

Mitochondrial transplantation therapy inhibit carbon tetrachloride‐induced liver injury through scavenging free radicals and protecting hepatocytes

(2020) Zizhen Zhao et al.   Bioengineering & Translational Medicine

The Ways of Actin: Why Tunneling Nanotubes Are Unique Cell Protrusions

(2020) Nina Ljubojevic et al.   TRENDS IN CELL BIOLOGY

CD38-driven mitochondrial trafficking promotes bioenergetic plasticity in multiple myeloma

(2019) Christopher R. Marlein et al.   CANCER RESEARCH

Mitochondrial DNA copy number as a predictor of embryo viability

(2019) Gustavo N. Cecchino et al.   FERTILITY AND STERILITY

Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS

(2019) André Varcianna et al.   EBioMedicine

The Expanding and Unexpected Functions of Mitochondria Contact Sites

(2019) Laura L. Lackner   TRENDS IN CELL BIOLOGY

Mitochondrial transplantation regulates antitumour activity, chemoresistance and mitochondrial dynamics in breast cancer

(2019) Jui-Chih Chang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mesenchymal stem cells transfer mitochondria into cerebral microvasculature and promote recovery from ischemic stroke

(2019) Kaiming Liu et al.   MICROVASCULAR RESEARCH

Neuronal Mitophagy: Lessons from a Pathway Linked to Parkinson’s Disease

(2019) Olga Corti   NEUROTOXICITY RESEARCH

Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer

(2019) Luigi Ippolito et al.   ONCOGENE

Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View

(2019) Giovanna Cenini et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial DNA: Distribution, Mutations, and Elimination

(2019) Yan et al.   Cells

Mitophagy in Cancer: A Tale of Adaptation

(2019) Vara-Perez et al.   Cells

Primary allogeneic mitochondrial mix (PAMM) transfer/transplant by MitoCeption to address damage in PBMCs caused by ultraviolet radiation

(2019) Francisco Cabrera et al.   BMC BIOTECHNOLOGY

Mitochondrial transplantation ameliorates acute limb ischemia

(2019) Arzoo Orfany et al.   JOURNAL OF VASCULAR SURGERY

Ketogenic treatment reduces the percentage of a LHON heteroplasmic mutation and increases mtDNA amount of a LHON homoplasmic mutation

(2019) Sonia Emperador et al.   Orphanet Journal of Rare Diseases

New Frontiers in IVF: mtDNA and autologous germline mitochondrial energy transfer

(2019) Mauro Cozzolino et al.   Reproductive Biology and Endocrinology

Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer

(2019) Longfei Gao et al.   Frontiers in Cellular Neuroscience

Mesenchymal stem cell repression of Th17 cells is triggered by mitochondrial transfer

(2019) Patricia Luz-Crawford et al.   Stem Cell Research & Therapy

Delayed Transplantation of Autologous Mitochondria for Cardioprotection in a Porcine Model

(2019) David Blitzer et al.   ANNALS OF THORACIC SURGERY

Preischemic autologous mitochondrial transplantation by intracoronary injection for myocardial protection

(2019) Alvise Guariento et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Mitochondrial Structural Changes in the Pathogenesis of Diabetic Retinopathy

(2019) Roy et al.   Journal of Clinical Medicine

Mesenchymal Stem Cells for Regenerative Medicine

(2019) Yu Han et al.   Cells

Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress

(2019) Richard Burt et al.   BLOOD

Mitochondrial transplantation for myocardial protection in diabetic hearts

(2019) Ilias P Doulamis et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Mitochondrial Transfer Ameliorates Cognitive Deficits, Neuronal Loss, and Gliosis in Alzheimer’s Disease Mice

(2019) Keren Nitzan et al.   JOURNAL OF ALZHEIMERS DISEASE

Autologous mitochondrial microinjection; a strategy to improve the oocyte quality and subsequent reproductive outcome during aging

(2019) Halimeh Mobarak et al.   Cell and Bioscience

Mesenchymal stem cell‐derived extracellular vesicles for the treatment of acute respiratory distress syndrome: Concise Review

(2019) Aswin Abraham et al.   Stem Cells Translational Medicine

Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network

(2019) Junjie Gao et al.   Science Advances

Mitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury

(2019) Kamila Moskowitzova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy

(2019) Ana Latorre-Pellicer et al.   Cell Metabolism

Exercise and mitochondrial health

(2019) Jonathan M. Memme et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondrial fission regulates germ cell differentiation by suppressing ROS-mediated activation of Epidermal Growth Factor Signaling in the Drosophila larval testis

(2019) Rafael Sênos Demarco et al.   Scientific Reports

Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice

(2018) Kirsty Foote et al.   AGING CELL

Intercellular mitochondria trafficking highlighting the dual role of mesenchymal stem cells as both sensors and rescuers of tissue injury

(2018) Anne-Marie Rodriguez et al.   CELL CYCLE

Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multiple myeloma

(2018) Zhihong Zheng et al.   Journal of Hematology & Oncology

Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells

(2018) Jiancheng Wang et al.   Journal of Hematology & Oncology

Effects of Mitochondrial Transplantation on Bioenergetics, Cellular Incorporation, and Functional Recovery after Spinal Cord Injury

(2018) Jenna L. Gollihue et al.   JOURNAL OF NEUROTRAUMA

Miro1 Enhances Mitochondria Transfer from Multipotent Mesenchymal Stem Cells (MMSC) to Neural Cells and Improves the Efficacy of Cell Recovery

(2018) Valentina Babenko et al.   MOLECULES

Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder

(2018) Daniel Lindqvist et al.   NEUROPSYCHOPHARMACOLOGY

Brief Reports: Protective Effects of Endothelial Progenitor Cell-Derived Extracellular Mitochondria in Brain Endothelium

(2018) Kazuhide Hayakawa et al.   STEM CELLS

Mitochondria are transported along microtubules in membrane nanotubes to rescue distressed cardiomyocytes from apoptosis

(2018) Jing Shen et al.   Cell Death & Disease

Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe

(2018) Yasuhito Onodera et al.   Nature Communications

Delivery of exogenous mitochondria via centrifugation enhances cellular metabolic function

(2018) Mi Jin Kim et al.   Scientific Reports

Stem cell-derived mitochondria transplantation: a novel strategy and the challenges for the treatment of tissue injury

(2018) Jingyu Wang et al.   Stem Cell Research & Therapy

Mesenchymal stem cell-derived extracellular vesicles: novel frontiers in regenerative medicine

(2018) Somayeh Keshtkar et al.   Stem Cell Research & Therapy

Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cells

(2018) Kenneth P. Hough et al.   Redox Biology

The role of metabolism and tunneling nanotube-mediated intercellular mitochondria exchange in cancer drug resistance

(2018) Yalda Hekmatshoar et al.   BIOCHEMICAL JOURNAL

Dedifferentiation, transdifferentiation and cell fusion: in vivo reprogramming strategies for regenerative medicine

(2018) Martina Pesaresi et al.   FEBS Journal

Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin

(2018) Hideaki Goto et al.   ONCOGENE

TLR4-mediated activation of the ERK pathway following UVA irradiation contributes to increased cytokine and MMP expression in senescent human dermal fibroblasts

(2018) Seong-Wook Seo et al.   PLoS One

Muscle-derived autologous mitochondrial transplantation: A novel strategy for treating cerebral ischemic injury

(2018) Zhanqin Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Visualization of Annular Gap Junction Vesicle Processing: The Interplay Between Annular Gap Junctions and Mitochondria

(2018) Cheryl Bell et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic Targeting of Connexin Channels: New Views and Challenges

(2018) Tinneke Delvaeye et al.   TRENDS IN MOLECULAR MEDICINE

Connexin 43-Mediated Mitochondrial Transfer of iPSC-MSCs Alleviates Asthma Inflammation

(2018) Yin Yao et al.   Stem Cell Reports

Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes

(2018) Jaime Uhl et al.   Journal of Cell Communication and Signaling

Defective mitochondrial rRNA methyltransferase MRM2 causes MELAS-like clinical syndrome

(2017) Caterina Garone et al.   HUMAN MOLECULAR GENETICS

Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine

(2017) Francisco Vizoso et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

mtDNA copy number associated with age of onset in familial amyloid polyneuropathy

(2017) Diana Santos et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Autologous mitochondrial transplantation for dysfunction after ischemia-reperfusion injury

(2017) Sitaram M. Emani et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Intravenous administration of mitochondria for treating experimental Parkinson's disease

(2017) Xianxun Shi et al.   MITOCHONDRION

Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

(2017) Pasquale Sansone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder

(2017) Odile Robicsek et al.   SCHIZOPHRENIA BULLETIN

Human Adipose-Derived Mesenchymal Stem Cell-Secreted CXCL1 and CXCL8 Facilitate Breast Tumor Growth By Promoting Angiogenesis

(2017) Yuan Wang et al.   STEM CELLS

Cytotoxic stress induces transfer of mitochondria-associated human endogenous retroviral RNA and proteins between cancer cells

(2017) David Díaz-Carballo et al.   Oncotarget

Tunneling nanotubes promote intercellular mitochondria transfer followed by increased invasiveness in bladder cancer cells

(2017) Jinjin Lu et al.   Oncotarget

AIRE is a critical spindle-associated protein in embryonic stem cells

(2017) Bin Gu et al.   eLife

Mitochondrial respiratory gene expression is suppressed in many cancers

(2017) Ed Reznik et al.   eLife

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

(2017) Lan-Feng Dong et al.   eLife

Cell Connections by Tunneling Nanotubes: Effects of Mitochondrial Trafficking on Target Cell Metabolism, Homeostasis, and Response to Therapy

(2017) Marie-Luce Vignais et al.   Stem Cells International

Artificial Mitochondria Transfer: Current Challenges, Advances, and Future Applications

(2017) Andrés Caicedo et al.   Stem Cells International

Tunneling Nanotubes and Gap Junctions–Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions

(2017) Jennifer Ariazi et al.   Frontiers in Molecular Neuroscience

Mitotherapy for Fatty Liver by Intravenous Administration of Exogenous Mitochondria in Male Mice

(2017) Ailing Fu et al.   Frontiers in Pharmacology

Transit and integration of extracellular mitochondria in human heart cells

(2017) Douglas B. Cowan et al.   Scientific Reports

Molecular mechanisms regulating formation, trafficking and processing of annular gap junctions

(2016) Matthias M. Falk et al.   BMC CELL BIOLOGY

Communication of Ca2+ signals via tunneling membrane nanotubes is mediated by transmission of inositol trisphosphate through gap junctions

(2016) Jeffrey T. Lock et al.   CELL CALCIUM

Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells

(2016) Ting-Hsiang Wu et al.   Cell Metabolism

Transferring Xenogenic Mitochondria Provides Neural Protection against Ischemic Stress in Ischemic Rat Brains

(2016) Po-Jui Huang et al.   CELL TRANSPLANTATION

Mitochondria and Cancer

(2016) Wei-Xing Zong et al.   MOLECULAR CELL

ESeroS-GS Protects Neuronal Cells from Oxidative Stress by Stabilizing Lysosomes

(2016) Na Yang et al.   MOLECULES

Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing

(2016) Ana Latorre-Pellicer et al.   NATURE

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Stem cell-based therapies for tumors in the brain: are we there yet?

(2016) Khalid Shah   NEURO-ONCOLOGY

Miro sculpts mitochondrial dynamics in neuronal health and disease

(2016) Michael J. Devine et al.   NEUROBIOLOGY OF DISEASE

ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells

(2016) Samantha C. Lewis et al.   SCIENCE

Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson's disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine–induced neurotoxicity

(2016) Jui-Chih Chang et al.   Translational Research

Mitochondrial transfer of mesenchymal stem cells effectively protects corneal epithelial cells from mitochondrial damage

(2016) Dan Jiang et al.   Cell Death & Disease

Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells

(2016) Luigi Ippolito et al.   Oncotarget

Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

(2016) Snider Desir et al.   Oncotarget

Characteristics of Mitochondrial Transformation into Human Cells

(2016) E. E. Kesner et al.   Scientific Reports

Magnetomitotransfer: An efficient way for direct mitochondria transfer into cultured human cells

(2016) Tanja Macheiner et al.   Scientific Reports

Characterization of intercellular communication and mitochondrial donation by mesenchymal stromal cells derived from the human lung

(2016) Kenneth Andrew Sinclair et al.   Stem Cell Research & Therapy

iPSC-MSCs with High Intrinsic MIRO1 and Sensitivity to TNF-α Yield Efficacious Mitochondrial Transfer to Rescue Anthracycline-Induced Cardiomyopathy

(2016) Yuelin Zhang et al.   Stem Cell Reports

Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection

(2016) Douglas B. Cowan et al.   PLoS One

Distinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation

(2016) Shunsuke Kimura et al.   Scientific Reports

Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells

(2015) X Wang et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA

(2015) An S. Tan et al.   Cell Metabolism

Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression

(2015) Julie V. Philley et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitochondrial transfer from Wharton's jelly-derived mesenchymal stem cells to mitochondria-defective cells recaptures impaired mitochondrial function

(2015) Hung-Yu Lin et al.   MITOCHONDRION

Brain tumour cells interconnect to a functional and resistant network

(2015) Matthias Osswald et al.   NATURE

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease

(2015) James B. Stewart et al.   NATURE REVIEWS GENETICS

The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

(2015) Paolo Bernardi et al.   PHYSIOLOGICAL REVIEWS

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

(2015) Donald G. Phinney et al.   Nature Communications

MitoCeption as a new tool to assess the effects of mesenchymal stem/stromal cell mitochondria on cancer cell metabolism and function

(2015) Andrés Caicedo et al.   Scientific Reports

Improving the Post-Stroke Therapeutic Potency of Mesenchymal Multipotent Stromal Cells by Cocultivation With Cortical Neurons: The Role of Crosstalk Between Cells

(2015) Valentina A. Babenko et al.   Stem Cells Translational Medicine

Actin-dependent mitochondrial internalization in cardiomyocytes: evidence for rescue of mitochondrial function

(2015) C. A. Pacak et al.   Biology Open

Mitochondrial Transfer of Induced Pluripotent Stem Cell–Derived Mesenchymal Stem Cells to Airway Epithelial Cells Attenuates Cigarette Smoke–Induced Damage

(2014) Xiang Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Internalization of isolated functional mitochondria: involvement of macropinocytosis

(2014) Tomoya Kitani et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia–reperfusion model via tunneling nanotube like structure-mediated mitochondrial transfer

(2014) Kaiming Liu et al.   MICROVASCULAR RESEARCH

Transcellular degradation of axonal mitochondria

(2014) Chung-ha O. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria released by cells undergoing TNF-α-induced necroptosis act as danger signals

(2014) A Maeda et al.   Cell Death & Disease

Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury

(2013) Akihiro Masuzawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

MitoTimer

(2013) Genaro Hernandez et al.   Autophagy

Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance

(2013) Jennifer Pasquier et al.   Journal of Translational Medicine

Isolated Mitochondria Infusion Mitigates Ischemia-Reperfusion Injury of the Liver in Rats

(2013) Han-Chen Lin et al.   SHOCK

Nanotubular Crosstalk with Distressed Cardiomyocytes Stimulates the Paracrine Repair Function of Mesenchymal Stem Cells

(2013) Florence Figeac et al.   STEM CELLS

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Mitochondria: master regulators of danger signalling

(2012) Lorenzo Galluzzi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Functional Recovery of Human Cells Harbouring the Mitochondrial DNA Mutation MERRF A8344G via Peptide-Mediated Mitochondrial Delivery

(2012) Jui-Chih Chang et al.   NEUROSIGNALS

Mesenchymal Stem Cells Transfer Mitochondria to the Cells with Virtually No Mitochondrial Function but Not with Pathogenic mtDNA Mutations

(2012) Young Min Cho et al.   PLoS One

Developing Neurons Form Transient Nanotubes Facilitating Electrical Coupling and Calcium Signaling with Distant Astrocytes

(2012) Xiang Wang et al.   PLoS One

Vascular Smooth Muscle Cells Initiate Proliferation of Mesenchymal Stem Cells by Mitochondrial Transfer via Tunneling Nanotubes

(2012) Krishna C. Vallabhaneni et al.   STEM CELLS AND DEVELOPMENT

Human Mesenchymal Stem Cells Reprogram Adult Cardiomyocytes Toward a Progenitor-Like State Through Partial Cell Fusion and Mitochondria Transfer

(2011) Adrien Acquistapace et al.   STEM CELLS

Cell membrane permeabilization via connexin hemichannels in living and dying cells

(2010) Juan C. Sáez et al.   EXPERIMENTAL CELL RESEARCH

Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at Synapses

(2009) Andrew F. MacAskill et al.   NEURON

Injection of isolated mitochondria during early reperfusion for cardioprotection

(2008) James D. McCully et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY