Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multiple myeloma

NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase

(2017) Zhimin Gu et al.   Journal of Hematology & Oncology

Role of epigenetics-microRNA axis in drug resistance of multiple myeloma

(2017) Nasrin Rastgoo et al.   Journal of Hematology & Oncology

Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment

(2017) Go J. Yoshida   Journal of Hematology & Oncology

The Close Interconnection between Mitochondrial Dynamics and Mitophagy in Cancer

(2017) Matteo Bordi et al.   Frontiers in Oncology

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomib-based therapy

(2016) Dominik Dytfeld et al.   Oncotarget

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma

(2015) Prahlad V. Raninga et al.   Oncotarget

Mechanisms for autophagy modulation by isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells

(2015) Kaitlyn M. Dykstra et al.   Oncotarget

ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy

(2014) W. Wu et al.   EMBO REPORTS

Targeting SQSTM1/p62 Induces Cargo Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik

(2014) S. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Reactive oxygen species, glutathione, and thioredoxin influence suberoyl bishydroxamic acid-induced apoptosis in A549 lung cancer cells

(2014) Bo Ra You et al.   TUMOR BIOLOGY

Management of bone disease in multiple myeloma

(2014) Evangelos Terpos et al.   Expert Review of Hematology

Role of osteocytes in multiple myeloma bone disease

(2014) Jesus Delgado-Calle et al.   Current Opinion in Supportive and Palliative Care

Autophagy and human diseases

(2013) Peidu Jiang et al.   CELL RESEARCH

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial modulation decreases the bortezomib-resistance in multiple myeloma cells

(2013) I.S. Song et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy: shaping the tumor microenvironment and therapeutic response

(2013) Hannelore Maes et al.   TRENDS IN MOLECULAR MEDICINE

Proteasome inhibitors in multiple myeloma: 10 years later

(2012) P. Moreau et al.   BLOOD

The Relationship of Thioredoxin-1 and Cisplatin Resistance: Its Impact on ROS and Oxidative Metabolism in Lung Cancer Cells

(2012) M. Wangpaichitr et al.   MOLECULAR CANCER THERAPEUTICS

Blocking Autophagy Prevents Bortezomib-Induced NF-κB Activation by Reducing I-κBα Degradation in Lymphoma Cells

(2012) Li Jia et al.   PLoS One

Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1

(2011) Rong Zeng et al.   ACTA PHARMACOLOGICA SINICA

Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival

(2011) Mohamed Elgendy et al.   MOLECULAR CELL

Role of oxidative stress and DNA damage in human carcinogenesis

(2011) Thomas B. Kryston et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Homozygous Deletion Mapping in Myeloma Samples Identifies Genes and an Expression Signature Relevant to Pathogenesis and Outcome

(2010) N. J. Dickens et al.   CLINICAL CANCER RESEARCH

Redox metabolism and malignancy

(2010) Christina L Grek et al.   CURRENT OPINION IN PHARMACOLOGY

Autophagy Induction by Capsaicin in Malignant Human Breast Cells Is Modulated by p38 and Extracellular Signal-Regulated Mitogen-Activated Protein Kinases and Retards Cell Death by Suppressing Endoplasmic Reticulum Stress-Mediated Apoptosis

(2010) C.-H. Choi et al.   MOLECULAR PHARMACOLOGY

Thioredoxin and Cancer: A Role for Thioredoxin in all States of Tumor Oxygenation

(2010) Therese Christina Karlenius et al.   Cancers

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factor-α-induced cell death in MCF-7 cells

(2008) U. Sivaprasad et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE