Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity

Mitochondrial transfer from MSCs to T cells induces Treg differentiation and restricts inflammatory response

(2020) Angela C Court et al.   EMBO REPORTS

Blood contains circulating cell‐free respiratory competent mitochondria

(2020) Zahra Al Amir Dache et al.   FASEB JOURNAL

A lipase-independent pathway of lipid release and immune modulation by adipocytes

(2019) Stephen E. Flaherty et al.   SCIENCE

Mitochondrial transplantation regulates antitumour activity, chemoresistance and mitochondrial dynamics in breast cancer

(2019) Jui-Chih Chang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock

(2019) Anthony Orvedahl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity: a neuroimmunometabolic perspective

(2019) Chelsea M. Larabee et al.   Nature Reviews Endocrinology

An Integrated View of Immunometabolism

(2018) Yun Sok Lee et al.   CELL

Delivery of exogenous mitochondria via centrifugation enhances cellular metabolic function

(2018) Mi Jin Kim et al.   Scientific Reports

METABOLIC ENDOTOXEMIA PROMOTES ADIPOSE DYSFUNCTION AND INFLAMMATION IN HUMAN OBESITY

(2018) Mercedes Clemente-Postigo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitochondrial damage associated molecular patterns released by lung transplants are associated with primary graft dysfunction

(2018) Davide Scozzi et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The initiation of metabolic inflammation in childhood obesity

(2017) Kanakadurga Singer et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of innate and adaptive immunity in obesity-associated metabolic disease

(2017) Tracey McLaughlin et al.   JOURNAL OF CLINICAL INVESTIGATION

The Formyl Peptide Receptors: Diversity of Ligands and Mechanism for Recognition

(2017) Hui-Qiong He et al.   MOLECULES

Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing

(2017) Christina D. Camell et al.   NATURE

Inflammation, metaflammation and immunometabolic disorders

(2017) Gökhan S. Hotamisligil   NATURE

Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine

(2017) Roksana M Pirzgalska et al.   NATURE MEDICINE

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Adapting to obesity with adipose tissue inflammation

(2017) Shannon M. Reilly et al.   Nature Reviews Endocrinology

Heparin Increases Food Intake through AgRP Neurons

(2017) Canjun Zhu et al.   Cell Reports

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

(2017) Lan-Feng Dong et al.   eLife

Intercellular mitochondrial transfer: bioenergetic crosstalk between cells

(2016) Pratik Sinha et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Trends in Obesity Among Adults in the United States, 2005 to 2014

(2016) Katherine M. Flegal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Trends in Obesity Prevalence Among Children and Adolescents in the United States, 1988-1994 Through 2013-2014

(2016) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

Expansion of the Gene Ontology knowledgebase and resources

(2016)   NUCLEIC ACIDS RESEARCH

PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements

(2016) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Discovery of a proteinaceous cellular receptor for a norovirus

(2016) R. C. Orchard et al.   SCIENCE

Mitochondrial transfer of mesenchymal stem cells effectively protects corneal epithelial cells from mitochondrial damage

(2016) Dan Jiang et al.   Cell Death & Disease

Mitochondrial transplantation attenuates hypoxic pulmonary hypertension

(2016) Liping Zhu et al.   Oncotarget

Immune Regulation of Metabolic Homeostasis in Health and Disease

(2015) Jonathan R. Brestoff et al.   CELL

Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

(2015) Hans L. Mooij et al.   JOURNAL OF LIPID RESEARCH

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses

(2015) Ruijie Liu et al.   NUCLEIC ACIDS RESEARCH

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

(2014) L. H. Boudreau et al.   BLOOD

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis

(2014) Rajesh R. Rao et al.   CELL

Internalization of isolated functional mitochondria: involvement of macropinocytosis

(2014) Tomoya Kitani et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

(2014) Jonathan R. Brestoff et al.   NATURE

Mitochondria released by cells undergoing TNF-α-induced necroptosis act as danger signals

(2014) A Maeda et al.   Cell Death & Disease

Inflammatory Stimuli Reprogram Macrophage Phagocytosis to Macropinocytosis for the Rapid Elimination of Pathogens

(2014) Somdeb BoseDasgupta et al.   PLoS Pathogens

Advanced Heat Map and Clustering Analysis Using Heatmap3

(2014) Shilin Zhao et al.   Biomed Research International

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Pathview: an R/Bioconductor package for pathway-based data integration and visualization

(2013) Weijun Luo et al.   BIOINFORMATICS

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Mouse lines with photo-activatable mitochondria to study mitochondrial dynamics

(2012) Anh H. Pham et al.   GENESIS

Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice

(2012) Robert Caesar et al.   GUT

Association between variants of EXT2 and type 2 diabetes: a replication and meta-analysis

(2012) Lei Liu et al.   HUMAN GENETICS

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Regulation of the Formyl Peptide Receptor 1 (FPR1) Gene in Primary Human Macrophages

(2012) Claudio Gemperle et al.   PLoS One

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial Capture by a Transmissible Cancer

(2011) C. A. Rebbeck et al.   SCIENCE

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

GAGE: generally applicable gene set enrichment for pathway analysis

(2009) Weijun Luo et al.   BMC BIOINFORMATICS