Exercise and mitochondrial health

Resistance Exercise Improves Mitochondrial Quality Control in a Rat Model of Sporadic Inclusion Body Myositis

(2019) Jung-Hoon Koo et al.   GERONTOLOGY

Parkin overexpression protects from aging-related loss of muscle mass and strength

(2019) Jean-Philippe Leduc-Gaudet et al.   JOURNAL OF PHYSIOLOGY-LONDON

Quantitative 3D Mapping of the Human Skeletal Muscle Mitochondrial Network

(2019) Amy E. Vincent et al.   Cell Reports

Exercise-Induced Mitophagy in Skeletal Muscle and Heart

(2019) Yuntian Guan et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Extracellular Vesicles: Delivery Vehicles of Myokines

(2019) Eleonora Trovato et al.   Frontiers in Physiology

Mediators of Physical Activity Protection against ROS-Linked Skeletal Muscle Damage

(2019) Sergio Di Meo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of Tim23 Knockdown in vivo on Mitochondrial Protein Import and Retrograde Signaling to the UPRmt in Muscle

(2018) Ashley N Oliveira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Exercise induces TFEB expression and activity in skeletal muscle in a PGC-1α-dependent manner

(2018) Avigail T. Erlich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Parkin is required for exercise-induced mitophagy in muscle: impact of aging

(2018) Chris Chin Wah Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Emerging roles and regulation of MiT/TFE transcriptional factors

(2018) Min Yang et al.   Cell Communication and Signaling

Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise

(2018) Martin Whitham et al.   Cell Metabolism

UPRmt regulation and output: a stress response mediated by mitochondrial-nuclear communication

(2018) Andrew Melber et al.   CELL RESEARCH

Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic Perspectives

(2018) Jin-Sung Park et al.   Current Neurology and Neuroscience Reports

Effect of contractile activity on PGC-1α transcription in young and aged skeletal muscle

(2018) Heather N. Carter et al.   JOURNAL OF APPLIED PHYSIOLOGY

Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity

(2018) Heather N. Carter et al.   JOURNAL OF PHYSIOLOGY-LONDON

The multifaceted contributions of mitochondria to cellular metabolism

(2018) Jessica B. Spinelli et al.   NATURE CELL BIOLOGY

Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle

(2018) Chris Chin Wah Chen et al.   Skeletal Muscle

Maintenance of Skeletal Muscle Mitochondria in Health, Exercise, and Aging

(2018) David A. Hood et al.   Annual Review of Physiology

Mitochondrial breakdown in skeletal muscle and the emerging role of the lysosomes

(2018) Matthew Triolo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Regulation of autophagic and mitophagic flux during chronic contractile activity-induced muscle adaptations

(2018) Yuho Kim et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice

(2017) Aaron M. Gusdon et al.   EXPERIMENTAL GERONTOLOGY

Obesity Downregulates MicroRNA-126 Inducing Capillary Rarefaction in Skeletal Muscle: Effects of Aerobic Exercise Training

(2017) João Lucas Penteado Gomes et al.   Oxidative Medicine and Cellular Longevity

Nutrition and Training Influences on the Regulation of Mitochondrial Adenosine Diphosphate Sensitivity and Bioenergetics

(2017) Graham P. Holloway   SPORTS MEDICINE

Mitochondrial Nanotunnels

(2017) Amy E. Vincent et al.   TRENDS IN CELL BIOLOGY

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

(2017) Rhianna C. Laker et al.   Nature Communications

Power Grid Protection of the Muscle Mitochondrial Reticulum

(2017) Brian Glancy et al.   Cell Reports

Skeletal Muscle as an Endocrine Organ: The Role of Myokines in Exercise Adaptations

(2017) Christoph Hoffmann et al.   Cold Spring Harbor Perspectives in Medicine

Impact of Resistance Training on Skeletal Muscle Mitochondrial Biogenesis, Content, and Function

(2017) Thomas Groennebaek et al.   Frontiers in Physiology

Chronology of UPR activation in skeletal muscle adaptations to chronic contractile activity

(2016) Jonathan M. Memme et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Unravelling the mechanisms regulating muscle mitochondrial biogenesis

(2016) D. A. Hood et al.   BIOCHEMICAL JOURNAL

Physical Exercise and Brain Mitochondrial Fitness: The Possible Role Against Alzheimer's Disease

(2016) T.C. Bernardo et al.   BRAIN PATHOLOGY

The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR

(2016) Christopher J. Fiorese et al.   CURRENT BIOLOGY

Physical exercise, reactive oxygen species and neuroprotection

(2016) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

The regulation of autophagy during exercise in skeletal muscle

(2016) Anna Vainshtein et al.   JOURNAL OF APPLIED PHYSIOLOGY

Metabolic regulation of mitochondrial dynamics

(2016) Prashant Mishra et al.   JOURNAL OF CELL BIOLOGY

Autophagy plays a role in skeletal muscle mitochondrial biogenesis in an endurance exercise-trained condition

(2016) Jeong-sun Ju et al.   Journal of Physiological Sciences

Physiological adaptations to interval training and the role of exercise intensity

(2016) Martin J. MacInnis et al.   JOURNAL OF PHYSIOLOGY-LONDON

Swimming exercise increases serum irisin level and reduces body fat mass in high-fat-diet fed Wistar rats

(2016) Yun Lu et al.   Lipids in Health and Disease

Myokine Expression in Muscle and Myotubes in Response to Exercise Stimulation

(2016) JEFFREY D. COVINGTON et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

The rise of mitochondria in medicine

(2016) Martin Picard et al.   MITOCHONDRION

The potential of endurance exercise-derived exosomes to treat metabolic diseases

(2016) Adeel Safdar et al.   Nature Reviews Endocrinology

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

(2016) E. Q. Toyama et al.   SCIENCE

Molecular basis for an attenuated mitochondrial adaptive plasticity in aged skeletal muscle

(2016) Vladimir Ljubicic et al.   Aging-US

Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscle

(2015) Anna Vainshtein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses

(2015) Huifang Wei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Adaptations of skeletal muscle mitochondria to exercise training

(2015) Carsten Lundby et al.   EXPERIMENTAL PHYSIOLOGY

Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy

(2015) Weili Tian et al.   FEBS LETTERS

Resistance Exercise Training Alters Mitochondrial Function in Human Skeletal Muscle

(2015) CRAIG PORTER et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto(mito)phagy markers

(2015) I. Marques-Aleixo et al.   NEUROSCIENCE

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

(2015) Sarah E. Calvo et al.   NUCLEIC ACIDS RESEARCH

Mitochondria, Muscle Health, and Exercise with Advancing Age

(2015) Heather N. Carter et al.   PHYSIOLOGY

Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice

(2015) Jean-Philippe Leduc-Gaudet et al.   Oncotarget

The Protein Import Machinery of Mitochondria—A Regulatory Hub in Metabolism, Stress, and Disease

(2014) Angelika B. Harbauer et al.   Cell Metabolism

The mitochondrial unfolded protein response in mammalian physiology

(2014) Adrienne Mottis et al.   MAMMALIAN GENOME

Transcription could be the key to the selection advantage of mitochondrial deletion mutants in aging

(2014) A. Kowald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and modification proteomics during skeletal muscle ageing

(2013) Martin A. Baraibar et al.   BIOGERONTOLOGY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance

(2013) Vitor A. Lira et al.   FASEB JOURNAL

Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans

(2013) Gilles Gouspillou et al.   FASEB JOURNAL

Acute exercise remodels mitochondrial membrane interactions in mouse skeletal muscle

(2013) Martin Picard et al.   JOURNAL OF APPLIED PHYSIOLOGY

Microarray Analysis Reveals Novel Features of the Muscle Aging Process in Men and Women

(2013) Dongmei Liu et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

(2013) Oliver C. Losón et al.   MOLECULAR BIOLOGY OF THE CELL

Expression of mitochondrial fission and fusion regulatory proteins in skeletal muscle during chronic use and disuse

(2013) Sobia Iqbal et al.   MUSCLE & NERVE

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

(2013) Carmine Settembre et al.   NATURE CELL BIOLOGY

BDNF mediates adaptive brain and body responses to energetic challenges

(2013) Krisztina Marosi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

(2012) Anna-Maria Joseph et al.   AGING CELL

Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle

(2012) Michael F. O'Leary et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training

(2012) Erika Koltai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes

(2012) Robert A. Jacobs et al.   JOURNAL OF APPLIED PHYSIOLOGY

Genomic and Proteomic Profiling Reveals Reduced Mitochondrial Function and Disruption of the Neuromuscular Junction Driving Rat Sarcopenia

(2012) C. Ibebunjo et al.   MOLECULAR AND CELLULAR BIOLOGY

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

Transcriptional integration of mitochondrial biogenesis

(2012) Richard C. Scarpulla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2

(2012) Brooke M. Baker et al.   PLoS Genetics

An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle

(2011) Jonathan P. Little et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle

(2010) Brendan Egan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Tissue-specific differences in mitochondrial activity and biogenesis

(2010) Erika Fernández-Vizarra et al.   MITOCHONDRION

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Cellular Internalization of Exosomes Occurs Through Phagocytosis

(2010) Du Feng et al.   TRAFFIC

Diminished contraction-induced intracellular signaling towards mitochondrial biogenesis in aged skeletal muscle

(2009) Vladimir Ljubicic et al.   AGING CELL

Mechanisms of exercise-induced mitochondrial biogenesis in skeletal muscleThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) David A. Hood   Applied Physiology Nutrition and Metabolism

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

Antioxidants prevent health-promoting effects of physical exercise in humans

(2009) M. Ristow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions between ROS and AMP kinase activity in the regulation of PGC-1α transcription in skeletal muscle cells

(2008) Isabella Irrcher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Endurance Exercise as a Countermeasure for Aging

(2008) I. R. Lanza et al.   DIABETES

Multiple pathways for sorting mitochondrial precursor proteins

(2008) Natalia Bolender et al.   EMBO REPORTS

Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1α in human skeletal muscle

(2008) Martin J. Gibala et al.   JOURNAL OF APPLIED PHYSIOLOGY

Exercise-Induced Synaptogenesis in the Hippocampus Is Dependent on UCP2-Regulated Mitochondrial Adaptation

(2008) M. O. Dietrich et al.   JOURNAL OF NEUROSCIENCE

Mitochondria Are Linked to Calcium Stores in Striated Muscle by Developmentally Regulated Tethering Structures

(2008) Simona Boncompagni et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial function and apoptotic susceptibility in aging skeletal muscle

(2007) Béatrice Chabi et al.   AGING CELL

Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humans

(2007) Kirsten A. Burgomaster et al.   JOURNAL OF PHYSIOLOGY-LONDON