Tunneling Nanotubes and Gap Junctions–Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions

Tweety-Homolog 1 Drives Brain Colonization of Gliomas

(2017) Erik Jung et al.   JOURNAL OF NEUROSCIENCE

Femtosecond laser micro-machined polyimide films for cell scaffold applications

(2017) Ieva Antanavičiūtė et al.   Journal of Tissue Engineering and Regenerative Medicine

Tumor microtubes convey resistance to surgical lesions and chemotherapy in gliomas

(2017) Sophie Weil et al.   NEURO-ONCOLOGY

Influenza virus exploits tunneling nanotubes for cell-to-cell spread

(2017) Amrita Kumar et al.   Scientific Reports

Communication of Ca2+ signals via tunneling membrane nanotubes is mediated by transmission of inositol trisphosphate through gap junctions

(2016) Jeffrey T. Lock et al.   CELL CALCIUM

Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes

(2016) Saïda Abounit et al.   EMBO JOURNAL

Tunneling nanotubes mediate the transfer of stem cell marker CD133 between hematopoietic progenitor cells

(2016) Doreen Reichert et al.   EXPERIMENTAL HEMATOLOGY

Linked in: immunologic membrane nanotube networks

(2016) C. R. Zaccard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

163. Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model

(2016) Heloise P. Gaide Chevronnay et al.   MOLECULAR THERAPY

A malignant cellular network in gliomas: potential clinical implications

(2016) Matthias Osswald et al.   NEURO-ONCOLOGY

Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases

(2016) Saida Abounit et al.   Prion

Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics

(2016) T. Alexander Quinn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS

(2016) Megan V. Jackson et al.   STEM CELLS

Mitochondrial transfer of mesenchymal stem cells effectively protects corneal epithelial cells from mitochondrial damage

(2016) Dan Jiang et al.   Cell Death & Disease

Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

(2016) Snider Desir et al.   Oncotarget

Drosophila cells use nanotube-like structures to transfer dsRNA and RNAi machinery between cells

(2016) Margot Karlikow et al.   Scientific Reports

Relevance of HCN2-expressing human mesenchymal stem cells for the generation of biological pacemakers

(2016) Ieva Bruzauskaite et al.   Stem Cell Research & Therapy

Characterization of intercellular communication and mitochondrial donation by mesenchymal stromal cells derived from the human lung

(2016) Kenneth Andrew Sinclair et al.   Stem Cell Research & Therapy

Cells must express components of the planar cell polarity system and extracellular matrix to support cytonemes

(2016) Hai Huang et al.   eLife

iPSC-MSCs with High Intrinsic MIRO1 and Sensitivity to TNF-α Yield Efficacious Mitochondrial Transfer to Rescue Anthracycline-Induced Cardiomyopathy

(2016) Yuelin Zhang et al.   Stem Cell Reports

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

(2016) Meryem Tardivel et al.   Acta Neuropathologica Communications

Tunneling nanotubes mediate rescue of prematurely senescent endothelial cells by endothelial progenitors: exchange of lysosomal pool

(2016) Kaoru Yasuda et al.   Aging-US

Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes

(2016) Elise Delage et al.   Scientific Reports

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment

(2015) R. Polak et al.   BLOOD

Nanotubes Connect CD4+T Cells to Airway Smooth Muscle Cells: Novel Mechanism of T Cell Survival

(2015) Saba Al Heialy et al.   JOURNAL OF IMMUNOLOGY

Bone marrow-derived mesenchymal stem cells rescue injured H9c2 cells via transferring intact mitochondria through tunneling nanotubes in an in vitro simulated ischemia/reperfusion model

(2015) HUI HAN et al.   Molecular Medicine Reports

Rescue of Brain Function Using Tunneling Nanotubes Between Neural Stem Cells and Brain Microvascular Endothelial Cells

(2015) Xiaoqing Wang et al.   MOLECULAR NEUROBIOLOGY

Brain tumour cells interconnect to a functional and resistant network

(2015) Matthias Osswald et al.   NATURE

Lipid droplets as a novel cargo of tunnelling nanotubes in endothelial cells

(2015) Ksenia Astanina et al.   Scientific Reports

Mitochondrial Transfer of Induced Pluripotent Stem Cell–Derived Mesenchymal Stem Cells to Airway Epithelial Cells Attenuates Cigarette Smoke–Induced Damage

(2014) Xiang Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cytonemes as specialized signaling filopodia

(2014) T. B. Kornberg et al.   DEVELOPMENT

The contrasting roles of primary cilia and cytonemes in Hh signaling

(2014) Thomas B. Kornberg   DEVELOPMENTAL BIOLOGY

Miro1: New wheels for transferring mitochondria

(2014) G. Las et al.   EMBO JOURNAL

Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells

(2014) Venugopal Thayanithy et al.   EXPERIMENTAL CELL RESEARCH

Exogenous connexin43-expressing autologous skeletal myoblasts ameliorate mechanical function and electrical activity of the rabbit heart after experimental infarction

(2014) Ieva Antanavičiūtė et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Cutting Edge: Membrane Nanotubes In Vivo: A Feature of MHC Class II + Cells in the Mouse Cornea

(2014) Holly R. Chinnery et al.   JOURNAL OF IMMUNOLOGY

CD40L Induces Functional Tunneling Nanotube Networks Exclusively in Dendritic Cells Programmed by Mediators of Type 1 Immunity

(2014) Colleen R. Zaccard et al.   JOURNAL OF IMMUNOLOGY

Long-Distance Communication between Laryngeal Carcinoma Cells

(2014) Ieva Antanavičiūtė et al.   PLoS One

Cytoneme-Mediated Contact-Dependent Transport of the Drosophila Decapentaplegic Signaling Protein

(2014) S. Roy et al.   SCIENCE

Brief Reports: Lysosomal Cross-Correction by Hematopoietic Stem Cell-Derived Macrophages Via Tunneling Nanotubes

(2014) Swati Naphade et al.   STEM CELLS

Tumor-stromal cross talk: direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes

(2014) Venugopal Thayanithy et al.   Translational Research

Intercellular communication in malignant pleural mesothelioma: properties of tunneling nanotubes

(2014) Justin W. Ady et al.   Frontiers in Physiology

Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes

(2013) M. Costanzo et al.   JOURNAL OF CELL SCIENCE

Myo10 is a key regulator of TNT formation in neuronal cells

(2013) K. Gousset et al.   JOURNAL OF CELL SCIENCE

Selective Induction of CTL Helper Rather Than Killer Activity by Natural Epitope Variants Promotes Dendritic Cell-Mediated HIV-1 Dissemination

(2013) R. B. Mailliard et al.   JOURNAL OF IMMUNOLOGY

Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance

(2013) Jennifer Pasquier et al.   Journal of Translational Medicine

Hedgehog threads to spread

(2013) James Briscoe et al.   NATURE CELL BIOLOGY

Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia

(2013) Marcus Bischoff et al.   NATURE CELL BIOLOGY

Exploring the role of lipids in intercellular conduits: breakthroughs in the pipeline

(2013) Elise Delage et al.   Frontiers in Plant Science

Balancing Hedgehog, a retention and release equilibrium given by Dally, Ihog, Boi and shifted/DmWif

(2012) Aphrodite Bilioni et al.   DEVELOPMENTAL BIOLOGY

LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation

(2012) C. Schiller et al.   JOURNAL OF CELL SCIENCE

Wiring through tunneling nanotubes - from electrical signals to organelle transfer

(2012) S. Abounit et al.   JOURNAL OF CELL SCIENCE

Tunneling nanotubes, an emerging intercellular communication route in development

(2012) Hans-Hermann Gerdes et al.   MECHANISMS OF DEVELOPMENT

Multi-Level Communication of Human Retinal Pigment Epithelial Cells via Tunneling Nanotubes

(2012) Dierk Wittig et al.   PLoS One

Developing Neurons Form Transient Nanotubes Facilitating Electrical Coupling and Calcium Signaling with Distant Astrocytes

(2012) Xiang Wang et al.   PLoS One

Cytoneme-Mediated Delivery of Hedgehog Regulates the Expression of Bone Morphogenetic Proteins to Maintain Germline Stem Cells in Drosophila

(2012) Patricia Rojas-Ríos et al.   PLOS BIOLOGY

Long-distance electrical coupling via tunneling nanotubes

(2011) Xiang Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Active Generation and Propagation of Ca2+ Signals within Tunneling Membrane Nanotubes

(2011) Ian F. Smith et al.   BIOPHYSICAL JOURNAL

Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes

(2011) Kangmin He et al.   CARDIOVASCULAR RESEARCH

Specificity of Drosophila Cytonemes for Distinct Signaling Pathways

(2011) S. Roy et al.   SCIENCE

Tunneling-nanotube development in astrocytes depends on p53 activation

(2010) Y Wang et al.   CELL DEATH AND DIFFERENTIATION

Malaria parasites form filamentous cell-to-cell connections during reproduction in the mosquito midgut

(2010) Ingrid Rupp et al.   CELL RESEARCH

Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels

(2010) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Antigen Presentation and Gap Junction Mediated Cross-Presentation during Apoptosis

(2009) B. Pang et al.   JOURNAL OF IMMUNOLOGY

Prions hijack tunnelling nanotubes for intercellular spread

(2009) Karine Gousset et al.   NATURE CELL BIOLOGY

M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex

(2009) Koji Hase et al.   NATURE CELL BIOLOGY

Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking

(2008) E.A. Eugenin et al.   CELLULAR IMMUNOLOGY

Intercellular transfer mediated by tunneling nanotubes

(2008) Hans-Hermann Gerdes et al.   CURRENT OPINION IN CELL BIOLOGY

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

(2008) Stefanie Sowinski et al.   NATURE CELL BIOLOGY

Membrane nanotubes: dynamic long-distance connections between animal cells

(2008) Daniel M. Davis et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Gamma-Herpesvirus Glycoprotein Complex Manipulates Actin to Promote Viral Spread

(2008) Michael B. Gill et al.   PLoS One