Autologous mitochondrial microinjection; a strategy to improve the oocyte quality and subsequent reproductive outcome during aging

Physiological impact of extracellular vesicles on female reproductive system; highlights to possible restorative effects on female age-related fertility

(2019) Halimeh Mobarak et al.   BIOFACTORS

New Frontiers in IVF: mtDNA and autologous germline mitochondrial energy transfer

(2019) Mauro Cozzolino et al.   Reproductive Biology and Endocrinology

The transgenerational effects of oocyte mitochondrial supplementation

(2019) Justin C. St. John et al.   Scientific Reports

Autologous mitochondrial transfer as a complementary technique to intracytoplasmic sperm injection to improve embryo quality in patients undergoing in vitro fertilization—a randomized pilot study

(2018) Elena Labarta et al.   FERTILITY AND STERILITY

Polar body transfer restores the developmental potential of oocytes to blastocyst stage in a case of repeated embryo fragmentation

(2017) Shuo-Ping Zhang et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Artificial Mitochondria Transfer: Current Challenges, Advances, and Future Applications

(2017) Andrés Caicedo et al.   Stem Cells International

First live birth using human oocytes reconstituted by spindle nuclear transfer for mitochondrial DNA mutation causing Leigh syndrome

(2016) J. Zhang et al.   FERTILITY AND STERILITY

Poor embryo development in post-ovulatoryin vivo-aged mouse oocytes is associated with mitochondrial dysfunction, but mitochondrial transfer from somatic cells is not sufficient for rejuvenation

(2016) Hideki Igarashi et al.   HUMAN REPRODUCTION

Ovarian ageing: the role of mitochondria in oocytes and follicles

(2016) Pascale May-Panloup et al.   HUMAN REPRODUCTION UPDATE

Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency

(2016) Gael L. M. Cagnone et al.   Scientific Reports

Oocyte mitochondrial function and reproduction

(2015) Elnur Babayev et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Oogonial Precursor Cell-Derived Autologous Mitochondria Injection to Improve Outcomes in Women With Multiple IVF Failures Due to Low Oocyte Quality

(2015) Kutluk Oktay et al.   Reproductive Sciences

Autologous Germline Mitochondrial Energy Transfer (AUGMENT) in Human Assisted Reproduction

(2015) Dori Woods et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Altered Levels of Mitochondrial DNA Are Associated with Female Age, Aneuploidy, and Provide an Independent Measure of Embryonic Implantation Potential

(2015) Elpida Fragouli et al.   PLoS Genetics

Polar Body Genome Transfer for Preventing the Transmission of Inherited Mitochondrial Diseases

(2014) Tian Wang et al.   CELL

L-carnitine supplementation during vitrification of mouse germinal vesicle stage-oocytes and their subsequent in vitro maturation improves meiotic spindle configuration and mitochondrial distribution in metaphase II oocytes

(2014) A. R. Moawad et al.   HUMAN REPRODUCTION

Associations Between Insulin Resistance, Free Fatty Acids, and Oocyte Quality in Polycystic Ovary Syndrome During In Vitro Fertilization

(2014) Zhihong Niu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The impact of mitochondrial function/dysfunction on IVF and new treatment possibilities for infertility

(2014) Heide Schatten et al.   Reproductive Biology and Endocrinology

Hereditary mtDNA Heteroplasmy: A Baseline for Aging?

(2013) Michael Keogh et al.   Cell Metabolism

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

(2013) Jaime M. Ross et al.   NATURE

Age-Associated Metabolic and Morphologic Changes in Mitochondria of Individual Mouse and Hamster Oocytes

(2013) Fatma Simsek-Duran et al.   PLoS One

Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants

(2012) Daniel Paull et al.   NATURE

The contribution of mitochondrial function to reproductive aging

(2011) Yaakov Bentov et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Effect of maternal age on mitochondrial DNA copy number, ATP content and IVF outcome of bovine oocytes

(2011) Hisataka Iwata et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Mitochondria: The calcium connection

(2010) Laura Contreras et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial energy metabolism and ageing

(2010) Ivana Bratic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial genetic diseases

(2010) Marni J Falk et al.   CURRENT OPINION IN PEDIATRICS

Mitochondrial changes in aged oocytes and improvement of fertility rate through autologous platelets mitochondrial microinjection

(2010) F. Li et al.   FERTILITY AND STERILITY

Mitochondrial function in the human oocyte and embryo and their role in developmental competence

(2010) Jonathan Van Blerkom   MITOCHONDRION

Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease

(2010) Lyndsey Craven et al.   NATURE

Pronounced Segregation of Donor Mitochondria Introduced by Bovine Ooplasmic Transfer to the Female Germ-Line1

(2009) Christina Ramires Ferreira et al.   BIOLOGY OF REPRODUCTION

Embryo Mitochondrial DNA Depletion Is Reversed During Early Embryogenesis in Cattle1

(2009) Marcos R. Chiaratti et al.   BIOLOGY OF REPRODUCTION

Microinjection of serum-starved mitochondria derived from somatic cells affects parthenogenetic development of bovine and murine oocytes

(2009) Kumiko Takeda et al.   MITOCHONDRION

Mitochondrial gene replacement in primate offspring and embryonic stem cells

(2009) Masahito Tachibana et al.   NATURE

Effects of Ooplasm Manipulation on DNA Methylation and Growth of Progeny in Mice1

(2008) Yong Cheng et al.   BIOLOGY OF REPRODUCTION

A systematic look at an old problem

(2008) Thomas B. L. Kirkwood   NATURE