Impaired insulin signalling and allostatic load in Alzheimer disease

Head injury and 25‐year risk of dementia

(2021) Andrea L. C. Schneider et al.   Alzheimers & Dementia

Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers

(2021) Andre F. Batista et al.   Journal of Neuroinflammation

Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer’s disease

(2021) Mauricio M. Oliveira et al.   Science Signaling

Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer’s subjects?

(2021) Grazia Daniela Femminella et al.   Alzheimers Research & Therapy

Association Between Age at Diabetes Onset and Subsequent Risk of Dementia

(2021) Claudio Barbiellini Amidei et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Microglia use TAM receptors to detect and engulf amyloid β plaques

(2021) Youtong Huang et al.   NATURE IMMUNOLOGY

Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease

(2021) Natalia M. Lyra e Silva et al.   Translational Psychiatry

Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens

(2021) Weikang Cai et al.   DIABETES

Peripheral and central immune system crosstalk in Alzheimer disease — a research prospectus

(2021) Brianne M. Bettcher et al.   Nature Reviews Neurology

Hippocampal-specific insulin resistance elicits behavioral despair and hippocampal dendritic atrophy

(2021) L.P. Reagan et al.   Neurobiology of Stress

A future for the world's children? A WHO–UNICEF–Lancet Commission

(2020) Helen Clark et al.   LANCET

Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation

(2020) Prerana Shrestha et al.   NATURE NEUROSCIENCE

A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse

(2020) Min Sung Gee et al.   Alzheimers Research & Therapy

Behavioral Abnormalities in Knockout and Humanized Tau Mice

(2020) Rafaella Araujo Gonçalves et al.   Frontiers in Endocrinology

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

(2020) Gill Livingston et al.   LANCET

Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance

(2020) Carla Nasca et al.   MOLECULAR PSYCHIATRY

Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia

(2020) Suzanne Craft et al.   JAMA Neurology

The unfolded protein response is activated in the olfactory system in Alzheimer’s disease

(2020) Helen C. Murray et al.   Acta Neuropathologica Communications

eIF2α controls memory consolidation via excitatory and somatostatin neurons

(2020) Vijendra Sharma et al.   NATURE

Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer’s Disease

(2020) Joseph W. Lewcock et al.   NEURON

Allostatic Load and Its Impact on Health: A Systematic Review

(2020) Jenny Guidi et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

c-Jun N-Terminal Kinase Inhibitors as Potential Leads for New Therapeutics for Alzheimer’s Diseases

(2020) Stephanie Cristine Hepp Rehfeldt et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploring brain insulin resistance in adults with bipolar depression using extracellular vesicles of neuronal origin

(2020) Rodrigo B. Mansur et al.   JOURNAL OF PSYCHIATRIC RESEARCH

The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer’s disease

(2020) Niklas Lonnemann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diet-Derived Fatty Acids, Brain Inflammation, and Mental Health

(2019) Helen M. Melo et al.   Frontiers in Neuroscience

The Link Between Tau and Insulin Signaling: Implications for Alzheimer’s Disease and Other Tauopathies

(2019) Rafaella Araujo Gonçalves et al.   Frontiers in Cellular Neuroscience

Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior

(2019) Marion Soto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroinflammation in mild cognitive impairment and Alzheimer’s disease: A meta-analysis

(2019) Steven Bradburn et al.   AGEING RESEARCH REVIEWS

Brain insulin resistance: A treatment target for cognitive impairment and anhedonia in depression

(2019) Julia A. Hamer et al.   EXPERIMENTAL NEUROLOGY

Insulin Modulates Excitatory Synaptic Transmission and Synaptic Plasticity in the Mouse Hippocampus

(2019) Fangli Zhao et al.   NEUROSCIENCE

Population attributable fractions for risk factors for dementia in low-income and middle-income countries: an analysis using cross-sectional survey data

(2019) Naaheed Mukadam et al.   Lancet Global Health

Insulin Resistance as a Shared Pathogenic Mechanism Between Depression and Type 2 Diabetes

(2019) Natalia de M. Lyra e Silva et al.   Frontiers in Psychiatry

Chronic synaptic insulin resistance after traumatic brain injury abolishes insulin protection from amyloid beta and tau oligomer-induced synaptic dysfunction

(2019) Whitney Franklin et al.   Scientific Reports

Association of Extracellular Vesicle Biomarkers With Alzheimer Disease in the Baltimore Longitudinal Study of Aging

(2019) Dimitrios Kapogiannis et al.   JAMA Neurology

NLRP3 inflammasome activation drives tau pathology

(2019) Christina Ising et al.   NATURE

GluT4: A central player in hippocampal memory and brain insulin resistance

(2019) Ewan C. McNay et al.   EXPERIMENTAL NEUROLOGY

Insulin modulates hippocampally-mediated spatial working memory via glucose transporter-4

(2018) J. Pearson-Leary et al.   BEHAVIOURAL BRAIN RESEARCH

Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice

(2018) Zhenri Ou et al.   BRAIN BEHAVIOR AND IMMUNITY

Association of childhood stress with late-life dementia and Alzheimer’s disease: the KIHD study

(2018) Gwendolyn A R Donley et al.   EUROPEAN JOURNAL OF PUBLIC HEALTH

Insulin regulates astrocyte gliotransmission and modulates behavior

(2018) Weikang Cai et al.   JOURNAL OF CLINICAL INVESTIGATION

The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease

(2018) Andre F Batista et al.   JOURNAL OF PATHOLOGY

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

(2018) Steven E. Arnold et al.   Nature Reviews Neurology

Crosstalk between endoplasmic reticulum stress and brain inflammation in Alzheimer's disease

(2018) Luis E. Santos et al.   NEUROPHARMACOLOGY

Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer’s disease.

(2018) Jeff Schaffert et al.   NEUROPSYCHOLOGY

Epigenetics and Epigenomics: Implications for Diabetes and Obesity

(2018) Evan D. Rosen et al.   DIABETES

Differential Activation of mTOR Complex 1 Signaling in Human Brain with Mild to Severe Alzheimer's Disease

(2018) Yong-Xin Sun et al.   JOURNAL OF ALZHEIMERS DISEASE

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

SOCS3 as a future target to treat metabolic disorders

(2018) João A.B. Pedroso et al.   Hormones-International Journal of Endocrinology and Metabolism

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

Routes for the delivery of insulin to the central nervous system: A comparative review

(2018) Elizabeth M. Rhea et al.   EXPERIMENTAL NEUROLOGY

Amyloid-β and islet amyloid pathologies link Alzheimer’s disease and type 2 diabetes in a transgenic model

(2017) Nadeeja Wijesekara et al.   FASEB JOURNAL

Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer’s Disease

(2017) Yujiao Lu et al.   JOURNAL OF ALZHEIMERS DISEASE

mTORC2 (Rictor) in Alzheimer’s Disease and Reversal of Amyloid-β Expression-Induced Insulin Resistance and Toxicity in Rat Primary Cortical Neurons

(2017) Han-Kyu Lee et al.   JOURNAL OF ALZHEIMERS DISEASE

Tau deletion promotes brain insulin resistance

(2017) Elodie Marciniak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes

(2017) Zhengqiu Zhou et al.   Journal of Neuroinflammation

Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model

(2017) Seung Hyun Baek et al.   JOURNAL OF NEUROSCIENCE

Absence of CX3CR1 impairs the internalization of Tau by microglia

(2017) Marta Bolós et al.   Molecular Neurodegeneration

Markers of microglia in post-mortem brain samples from patients with Alzheimer’s disease: a systematic review

(2017) K E Hopperton et al.   MOLECULAR PSYCHIATRY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

ER stress and the unfolded protein response in neurodegeneration

(2017) Claudio Hetz et al.   Nature Reviews Neurology

Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease

(2017) Ramon Velazquez et al.   NEUROBIOLOGY OF AGING

Blood pressure from mid‐ to late life and risk of incident dementia

(2017) Emer R. McGrath et al.   NEUROLOGY

Allostasis and the Epigenetics of Brain and Body Health Over the Life Course

(2017) Bruce S. McEwen   JAMA Psychiatry

Insulin Levels are Decreased in the Cerebrospinal Fluid of Women with Prodomal Alzheimer's Disease

(2017) Francisco J. Gil-Bea et al.   JOURNAL OF ALZHEIMERS DISEASE

Overexpression of matrix metalloproteinase-9 (MMP-9) rescues insulin-mediated impairment in the 5XFAD model of Alzheimer’s disease

(2017) Archontia Kaminari et al.   Scientific Reports

In pursuit of resilience: stress, epigenetics, and brain plasticity

(2016) Bruce S. McEwen   Annals of the New York Academy of Sciences

The role of insulin in the vascular contributions to age-related dementia

(2016) Timothy M. Hughes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function

(2016) Hyo Youl Moon et al.   Cell Metabolism

Traumatic brain injury and obesity induce persistent central insulin resistance

(2016) Kate Karelina et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The role of endoplasmic reticulum stress in hippocampal insulin resistance

(2016) Catrina Sims-Robinson et al.   EXPERIMENTAL NEUROLOGY

Role of Suppressor of Cytokine Signaling 3 (SOCS3) in Altering Activated Microglia Phenotype in APPswe/PS1dE9 Mice

(2016) Naotoshi Iwahara et al.   JOURNAL OF ALZHEIMERS DISEASE

Insulin Resistance is Associated with Increased Levels of Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease and Reduced Memory Function in At-Risk Healthy Middle-Aged Adults

(2016) Siobhan M. Hoscheidt et al.   JOURNAL OF ALZHEIMERS DISEASE

Insulin resistance is associated with lower arterial blood flow and reduced cortical perfusion in cognitively asymptomatic middle-aged adults

(2016) Siobhan M Hoscheidt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-  Oligomers in Mice

(2016) J. H. Ledo et al.   JOURNAL OF NEUROSCIENCE

An epigenetic mechanism links socioeconomic status to changes in depression-related brain function in high-risk adolescents

(2016) J R Swartz et al.   MOLECULAR PSYCHIATRY

Insulin resistance—a missing link no more

(2016) N L Rasgon et al.   MOLECULAR PSYCHIATRY

The effects of childhood maltreatment on brain structure, function and connectivity

(2016) Martin H. Teicher et al.   NATURE REVIEWS NEUROSCIENCE

The unfolded protein response in neurodegenerative diseases: a neuropathological perspective

(2015) Wiep Scheper et al.   ACTA NEUROPATHOLOGICA

Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity

(2015) Claudia A. Grillo et al.   DIABETES

Alzheimer-associated A  oligomers impact the central nervous system to induce peripheral metabolic deregulation

(2015) J. R. Clarke et al.   EMBO Molecular Medicine

Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD

(2015) Antonella Tramutola et al.   JOURNAL OF NEUROCHEMISTRY

Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein

(2015) C. H. Lyoo et al.   JOURNAL OF NUCLEAR MEDICINE

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

(2015) Tiia Ngandu et al.   LANCET

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Proteostasis control by the unfolded protein response

(2015) Claudio Hetz et al.   NATURE CELL BIOLOGY

Hippocampal insulin resistance and cognitive dysfunction

(2015) Geert Jan Biessels et al.   NATURE REVIEWS NEUROSCIENCE

Epigenetic and transgenerational reprogramming of brain development

(2015) Tracy L. Bale   NATURE REVIEWS NEUROSCIENCE

Type 2 diabetes mellitus and biomarkers of neurodegeneration

(2015) Chris Moran et al.   NEUROLOGY

Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer’s disease brains and human microglia

(2015) D.G. Walker et al.   NEUROSCIENCE

Insulin resistance in brain alters dopamine turnover and causes behavioral disorders

(2015) Andre Kleinridders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy in Alzheimer’s disease

(2015) Ameneh Zare-shahabadi et al.   REVIEWS IN THE NEUROSCIENCES

Self Reported Childhood Difficulties, Adult Multimorbidity and Allostatic Load. A Cross-Sectional Analysis of the Norwegian HUNT Study

(2015) Margret Olafia Tomasdottir et al.   PLoS One

Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer’s disease and tauopathies

(2014) Mark Yarchoan et al.   ACTA NEUROPATHOLOGICA

Insulin Action in Brain Regulates Systemic Metabolism and Brain Function

(2014) A. Kleinridders et al.   DIABETES

Understanding the cause of sporadic Alzheimer’s disease

(2014) Henrik Zetterberg et al.   Expert Review of Neurotherapeutics

Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice

(2014) Arnaud François et al.   Journal of Neuroinflammation

Preliminary Evidence for Sensitive Periods in the Effect of Childhood Sexual Abuse on Regional Brain Development

(2014) Susan L. Andersen et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity

(2014) Ana Paula Arruda et al.   NATURE MEDICINE

Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion

(2014) Tariq Ahmed et al.   NEUROBIOLOGY OF AGING

Association of type 2 diabetes with brain atrophy and cognitive impairment

(2014) R. O. Roberts et al.   NEUROLOGY

TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys

(2013) Mychael V. Lourenco et al.   Cell Metabolism

Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence

(2013) Jessica Freiherr et al.   CNS DRUGS

Insulin Regulates the Unfolded Protein Response in Human Adipose Tissue

(2013) G. Boden et al.   DIABETES

Alzheimer’s disease and insulin resistance: translating basic science into clinical applications

(2013) Fernanda G. De Felice   JOURNAL OF CLINICAL INVESTIGATION

Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits

(2013) Tao Ma et al.   NATURE NEUROSCIENCE

The Effects of Stress on Physical Activity and Exercise

(2013) Matthew A. Stults-Kolehmainen et al.   SPORTS MEDICINE

BDNF mediates adaptive brain and body responses to energetic challenges

(2013) Krisztina Marosi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diabetes mellitus and risk of dementia: A meta-analysis of prospective observational studies

(2013) Kapil Gudala et al.   Journal of Diabetes Investigation

Blood Pressure and Progression of Brain Atrophy

(2013) Hadassa M. Jochemsen   JAMA Neurology

Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats

(2013) Gisele Castro et al.   FEBS Open Bio

Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

(2012) M. Manczak et al.   HUMAN MOLECULAR GENETICS

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers

(2012) Theresa R. Bomfim et al.   JOURNAL OF CLINICAL INVESTIGATION

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice

(2012) J H Ledo et al.   MOLECULAR PSYCHIATRY

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

The Diabetes Drug Liraglutide Ameliorates Aberrant Insulin Receptor Localisation and Signalling in Parallel with Decreasing Both Amyloid-β Plaque and Glial Pathology in a Mouse Model of Alzheimer’s Disease

(2012) Caitriona M. Long-Smith et al.   NEUROMOLECULAR MEDICINE

Link between the renin–angiotensin system and insulin resistance: Implications for cardiovascular disease

(2012) Ming-Sheng Zhou et al.   VASCULAR MEDICINE

Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment

(2011) Suzanne Craft   ARCHIVES OF NEUROLOGY

Downregulation of hypothalamic insulin receptor expression elicits depressive-like behaviors in rats

(2011) Claudia A. Grillo et al.   BEHAVIOURAL BRAIN RESEARCH

Limbic Scars: Long-Term Consequences of Childhood Maltreatment Revealed by Functional and Structural Magnetic Resonance Imaging

(2011) Udo Dannlowski et al.   BIOLOGICAL PSYCHIATRY

Effect of Intranasal Insulin on Cognitive Function: A Systematic Review

(2011) Elad Shemesh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal  -Catenin Pathway Function in an Alzheimer's Disease Model

(2011) M. Kitazawa et al.   JOURNAL OF IMMUNOLOGY

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

(2011) Ying Liu et al.   JOURNAL OF PATHOLOGY

Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging

(2011) J. Eric Ahlskog et al.   MAYO CLINIC PROCEEDINGS

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

(2011) Sergio T. Ferreira et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Interleukin-1β May Mediate Insulin Resistance in Liver-Derived Cells in Response to Adipocyte Inflammation

(2010) Ori Nov et al.   ENDOCRINOLOGY

Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau

(2010) Antonella Caccamo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin metabolism and the risk of Alzheimer disease: The Rotterdam Study

(2010) E. M. C. Schrijvers et al.   NEUROLOGY

Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent

(2009) C.A. Grillo et al.   BRAIN RESEARCH

Association Between Raised Inflammatory Markers and Cognitive Decline in Elderly People With Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study

(2009) R. E. Marioni et al.   DIABETES

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

(2009) Christine L. Hsieh et al.   JOURNAL OF NEUROCHEMISTRY

 -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin

(2009) Q.-L. Ma et al.   JOURNAL OF NEUROSCIENCE

The Insulin/Akt Signaling Pathway Is Targeted by Intracellular β-Amyloid

(2009) Han-Kyu Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Allostatic load biomarkers of chronic stress and impact on health and cognition

(2009) Robert-Paul Juster et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

(2009) Fernanda G. De Felice et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

(2008) Solomon S Shaftel et al.   Journal of Neuroinflammation

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

(2008) Aileen M. Moloney et al.   NEUROBIOLOGY OF AGING

10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

(2008) Rury R. Holman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Slow-wave sleep and the risk of type 2 diabetes in humans

(2008) E. Tasali et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid beta oligomers induce impairment of neuronal insulin receptors

(2007) Wei-Qin Zhao et al.   FASEB JOURNAL