Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity
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Title
Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity
Authors
Keywords
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Journal
NATURE MEDICINE
Volume 20, Issue 12, Pages 1427-1435
Publisher
Springer Nature
Online
2014-11-25
DOI
10.1038/nm.3735
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Note: Only part of the references are listed.- Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Is Required for Insulin Signaling and Is Implicated in Hepatic Insulin Resistance
- (2014) E. Tubbs et al. DIABETES
- Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance
- (2013) Marc Schneeberger et al. CELL
- Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease
- (2013) Karima Begriche et al. HEPATOLOGY
- Autophagosomes form at ER–mitochondria contact sites
- (2013) Maho Hamasaki et al. NATURE
- Calcium Signaling through CaMKII Regulates Hepatic Glucose Production in Fasting and Obesity
- (2012) Lale Ozcan et al. Cell Metabolism
- Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver
- (2012) T. Otoda et al. DIABETES
- Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
- (2012) Estela Area-Gomez et al. EMBO JOURNAL
- An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers
- (2012) Theresa R. Bomfim et al. JOURNAL OF CLINICAL INVESTIGATION
- Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes
- (2012) Yiguo Wang et al. NATURE
- Endoplasmic reticulum–mitochondria contacts: function of the junction
- (2012) Ashley A. Rowland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondria as sensors and regulators of calcium signalling
- (2012) Rosario Rizzuto et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
- (2012) D. Sebastian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders
- (2011) Lale Ozcan et al. Annual Review of Medicine
- Urban planning of the endoplasmic reticulum (ER): How diverse mechanisms segregate the many functions of the ER
- (2011) Emily M. Lynes et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Sodium Phenylbutyrate, a Drug With Known Capacity to Reduce Endoplasmic Reticulum Stress, Partially Alleviates Lipid-Induced Insulin Resistance and β-Cell Dysfunction in Humans
- (2011) Changting Xiao et al. DIABETES
- Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress
- (2011) R. Bravo et al. JOURNAL OF CELL SCIENCE
- Mitochondrial Fission Contributes to Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle
- (2011) H.-F. Jheng et al. MOLECULAR AND CELLULAR BIOLOGY
- Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
- (2011) Suneng Fu et al. NATURE
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- ER Tubules Mark Sites of Mitochondrial Division
- (2011) J. R. Friedman et al. SCIENCE
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria
- (2010) César Cárdenas et al. CELL
- Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
- (2010) Gökhan S. Hotamisligil CELL
- Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women
- (2010) Marleen Kars et al. DIABETES
- The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes
- (2010) Mary-Elizabeth Patti et al. ENDOCRINE REVIEWS
- Prevalence and Trends in Obesity Among US Adults, 1999-2008
- (2010) Katherine M. Flegal JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Effects of a high-fat diet on energy metabolism and ROS production in rat liver
- (2010) Guillaume Vial et al. JOURNAL OF HEPATOLOGY
- Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface
- (2010) György Csordás et al. MOLECULAR CELL
- Ca2+ transfer from the ER to mitochondria: When, how and why
- (2009) Rosario Rizzuto et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response
- (2009) Sebastian Schuck et al. JOURNAL OF CELL BIOLOGY
- GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis
- (2009) Renata Sano et al. MOLECULAR CELL
- Foxo1 integrates insulin signaling with mitochondrial function in the liver
- (2009) Zhiyong Cheng et al. NATURE MEDICINE
- Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells
- (2009) Mariusz R Wieckowski et al. Nature Protocols
- Role of Mitochondrial Dysfunction in Insulin Resistance
- (2008) Jeong-a Kim et al. CIRCULATION RESEARCH
- Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss
- (2008) M. F. Gregor et al. DIABETES
- Increase in Endoplasmic Reticulum Stress-Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals
- (2008) G. Boden et al. DIABETES
- Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases
- (2008) Sudheer K. Mantena et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitofusin 2 tethers endoplasmic reticulum to mitochondria
- (2008) Olga Martins de Brito et al. NATURE
- Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis
- (2008) P Pinton et al. ONCOGENE
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