Chronic synaptic insulin resistance after traumatic brain injury abolishes insulin protection from amyloid beta and tau oligomer-induced synaptic dysfunction
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Title
Chronic synaptic insulin resistance after traumatic brain injury abolishes insulin protection from amyloid beta and tau oligomer-induced synaptic dysfunction
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-03
DOI
10.1038/s41598-019-44635-z
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Note: Only part of the references are listed.- Metabolic Dysfunction in Alzheimer’s Disease: From Basic Neurobiology to Clinical Approaches
- (2018) Julia R. Clarke et al. JOURNAL OF ALZHEIMERS DISEASE
- Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums
- (2018) Steven E. Arnold et al. Nature Reviews Neurology
- Intranasal insulin in Alzheimer's disease: Food for thought
- (2018) Colin D. Chapman et al. NEUROPHARMACOLOGY
- Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects
- (2018) Rudimar L. Frozza et al. Frontiers in Neuroscience
- Suppressor of Cytokine Signaling 3: Emerging Role Linking Central Insulin Resistance and Alzheimer’s Disease
- (2018) Lan Cao et al. Frontiers in Neuroscience
- Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies
- (2018) Michele M. Comerota et al. MOLECULAR NEUROBIOLOGY
- PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease
- (2017) Wei-Chun J. Hsu et al. EXPERIMENTAL NEUROLOGY
- LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent
- (2017) Daniela Puzzo et al. eLife
- Amyloid-β and Mitochondria in Aging and Alzheimer's Disease: Implications for Synaptic Damage and Cognitive Decline
- (2017) P. Hemachandra Reddy et al. JOURNAL OF ALZHEIMERS DISEASE
- Near infrared light decreases synaptic vulnerability to amyloid beta oligomers
- (2017) Michele M. Comerota et al. Scientific Reports
- Bilateral gene interaction hierarchy analysis of the cell death gene response emphasizes the significance of cell cycle genes following unilateral traumatic brain injury
- (2016) Todd E. White et al. BMC GENOMICS
- Traumatic brain injury and obesity induce persistent central insulin resistance
- (2016) Kate Karelina et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Polypathology and dementia after brain trauma: Does brain injury trigger distinct neurodegenerative diseases, or should they be classified together as traumatic encephalopathy?
- (2016) Patricia M. Washington et al. EXPERIMENTAL NEUROLOGY
- Changes in insulin and insulin signaling in Alzheimer’s disease: cause or consequence?
- (2016) Molly Stanley et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chronic Cognitive Dysfunction after Traumatic Brain Injury Is Improved with a Phosphodiesterase 4B Inhibitor
- (2016) D. J. Titus et al. JOURNAL OF NEUROSCIENCE
- A method to determine insulin responsiveness in synaptosomes isolated from frozen brain tissue
- (2016) Whitney Franklin et al. JOURNAL OF NEUROSCIENCE METHODS
- The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice
- (2016) Kendra L. Puig et al. NEUROBIOLOGY OF AGING
- Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
- (2016) M. Fá et al. Scientific Reports
- Hippocampal insulin resistance and cognitive dysfunction
- (2015) Geert Jan Biessels et al. NATURE REVIEWS NEUROSCIENCE
- Aberrant insulin signaling in Alzheimer's disease: current knowledge
- (2015) Gaurav Bedse et al. Frontiers in Neuroscience
- The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease
- (2014) Tara L. Spires-Jones et al. NEURON
- Insulin Receptor Signaling in Normal and Insulin-Resistant States
- (2014) J. Boucher et al. Cold Spring Harbor Perspectives in Biology
- Insulin in the Brain: Its Pathophysiological Implications for States Related with Central Insulin Resistance, Type 2 Diabetes and Alzheimer’s Disease
- (2014) Enrique Blázquez et al. Frontiers in Endocrinology
- Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response
- (2013) Todd E White et al. BMC GENOMICS
- Military Risk Factors for Cognitive Decline, Dementia and Alzheimer’s Disease
- (2013) Dallas Veitch et al. Current Alzheimer Research
- Enhancement of Vasoreactivity and Cognition by Intranasal Insulin in Type 2 Diabetes
- (2013) Vera Novak et al. DIABETES CARE
- Insulin-associated neuroinflammatory pathways as therapeutic targets for traumatic brain injury
- (2013) Christian D. Cerecedo-López et al. MEDICAL HYPOTHESES
- Molecular mechanisms of cognitive dysfunction following traumatic brain injury
- (2013) Kendall R. Walker et al. Frontiers in Aging Neuroscience
- Brain injury, neuroinflammation and Alzheimer's disease
- (2013) Joshua J. Breunig et al. Frontiers in Aging Neuroscience
- Dementia Resulting From Traumatic Brain Injury
- (2012) Sharon Shively et al. ARCHIVES OF NEUROLOGY
- Brain Insulin Resistance and Deficiency as Therapeutic Targets in Alzheimers Disease
- (2012) Suzanne M. de la Monte Current Alzheimer Research
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- Inflammation after trauma: Microglial activation and traumatic brain injury
- (2011) Anil F. Ramlackhansingh et al. ANNALS OF NEUROLOGY
- Controlled Cortical Impact Traumatic Brain Injury in 3xTg-AD Mice Causes Acute Intra-Axonal Amyloid- Accumulation and Independently Accelerates the Development of Tau Abnormalities
- (2011) H. T. Tran et al. JOURNAL OF NEUROSCIENCE
- Diabetic Patients With Traumatic Brain Injury: Insulin Deficiency Is Associated With Increased Mortality
- (2011) Eric J. Ley et al. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
- Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status
- (2010) Jennifer Rodriguez-Rivera et al. BEHAVIOURAL BRAIN RESEARCH
- Preparation and Characterization of Neurotoxic Tau Oligomers
- (2010) Cristian A. Lasagna-Reeves et al. BIOCHEMISTRY
- Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance
- (2010) Ewan C. McNay et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- The Alzheimer's disease mitochondrial cascade hypothesis: An update
- (2009) Russell H. Swerdlow et al. EXPERIMENTAL NEUROLOGY
- Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers
- (2009) Fernanda G. De Felice et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective induction of calcineurin activity and signaling by oligomeric amyloid beta
- (2008) Lindsay C. Reese et al. AGING CELL
- Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury
- (2008) Eric Lloyd et al. Journal of Neuroinflammation
- Amyloid beta oligomers induce impairment of neuronal insulin receptors
- (2007) Wei-Qin Zhao et al. FASEB JOURNAL
- Insulin rescues amyloid β-induced impairment of hippocampal long-term potentiation
- (2007) Cheng-Che Lee et al. NEUROBIOLOGY OF AGING
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