Markers of microglia in post-mortem brain samples from patients with Alzheimer’s disease: a systematic review

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease

(2017) Nicholas T. Seyfried et al.   Cell Systems

Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration

(2016) Elisabeth Sanchez-Mejias et al.   ACTA NEUROPATHOLOGICA

Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease

(2016) Danielle S. Davies et al.   BRAIN PATHOLOGY

Augmented expression of TSPO after intracerebral hemorrhage: a role in inflammation?

(2016) Frederick Bonsack et al.   Journal of Neuroinflammation

Brain omega-3 polyunsaturated fatty acids modulate microglia cell number and morphology in response to intracerebroventricular amyloid-β 1-40 in mice

(2016) Kathryn E. Hopperton et al.   Journal of Neuroinflammation

Microglial immunophenotype in dementia with Alzheimer’s pathology

(2016) Thais Minett et al.   Journal of Neuroinflammation

Comparison of Peritoneal Low-Molecular-Weight-Protein-Removal in CCPD and CAPD Patients Based on C-Terminal Agrin Fragment Clearance

(2016) Dominik Steubl et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Postmortem evidence of cerebral inflammation in schizophrenia: a systematic review

(2016) M O Trépanier et al.   MOLECULAR PSYCHIATRY

High Resolution Dissection of Reactive Glial Nets in Alzheimer’s Disease

(2016) David S. Bouvier et al.   Scientific Reports

The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia

(2015) Panos Roussos et al.   Alzheimers & Dementia

Stage-Specific Changes in Neurogenic and Glial Markers in Alzheimer’s Disease

(2015) Antigoni Ekonomou et al.   BIOLOGICAL PSYCHIATRY

An isoform-specific role of FynT tyrosine kinase in Alzheimer's disease

(2015) Chingli Lee et al.   JOURNAL OF NEUROCHEMISTRY

Neuroinflammatory Signals in Alzheimer Disease and APP/PS1 Transgenic Mice

(2015) Irene López-González et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein

(2015) C. H. Lyoo et al.   JOURNAL OF NUCLEAR MEDICINE

Effect of active Aβimmunotherapy on neurons in human Alzheimer's disease

(2015) Claire Paquet et al.   JOURNAL OF PATHOLOGY

Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease

(2015) Donna M. Wilcock et al.   NEUROBIOLOGY OF AGING

Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease

(2015) Michael M. Zeineh et al.   NEUROBIOLOGY OF AGING

Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex

(2015) Douglas G. Walker et al.   NEUROBIOLOGY OF AGING

Increased acetyl and total histone levels in post-mortem Alzheimer's disease brain

(2015) Pritika J. Narayan et al.   NEUROBIOLOGY OF DISEASE

TMEM119 marks a subset of microglia in the human brain

(2015) Jun-ichi Satoh et al.   NEUROPATHOLOGY

Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease

(2015) Xinzhong Li et al.   Scientific Reports

Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains

(2015) Douglas G. Walker et al.   Alzheimers Research & Therapy

R47H Variant ofTREM2Associated With Alzheimer Disease in a Large Late-Onset Family

(2015) Olena Korvatska et al.   JAMA Neurology

Cortical iron regulation and inflammatory response in Alzheimer's disease and APPSWE/PS1ΔE9 mice: a histological perspective

(2015) Mark D. Meadowcroft et al.   Frontiers in Neuroscience

Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation

(2015) Agnieszka Wlodarczyk et al.   Frontiers in Immunology

Disease-related microglia heterogeneity in the hippocampus of Alzheimer’s disease, dementia with Lewy bodies, and hippocampal sclerosis of aging

(2015) Adam D Bachstetter et al.   Acta Neuropathologica Communications

Olfactory Pathology in Central Nervous System Demyelinating Diseases

(2014) Gabriele C. DeLuca et al.   BRAIN PATHOLOGY

TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices

(2014) Lih-Fen Lue et al.   BRAIN PATHOLOGY

Astroglial cell subtypes in the cerebella of normal adults, elderly adults, and patients with Alzheimer's disease: A histological and immunohistochemical comparison

(2014) María-Isabel Álvarez et al.   GLIA

Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study

(2014) Pascal F. Durrenberger et al.   JOURNAL OF NEURAL TRANSMISSION

Microglia receptors and their implications in the response to amyloid β for Alzheimer’s disease pathogenesis

(2014) Deborah Doens et al.   Journal of Neuroinflammation

Proliferation in the Alzheimer Hippocampus Is due to Microglia, Not Astroglia, and Occurs at Sites of Amyloid Deposition

(2014) Michael W. Marlatt et al.   NEURAL PLASTICITY

Phenotypic profile of alternative activation marker CD163 is different in Alzheimer’s and Parkinson’s disease

(2014) Peixuan Pey et al.   Acta Neuropathologica Communications

A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease

(2013) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis

(2013) Isabel Lastres-Becker et al.   BRAIN

Inflammatory components in human Alzheimer’s disease and after active amyloid-β42 immunization

(2013) Elina Zotova et al.   BRAIN

Dissecting phenotypic traits linked to human resilience to Alzheimer’s pathology

(2013) Beatriz G. Perez-Nievas et al.   BRAIN

Increased Amoeboid Microglial Density in the Olfactory Bulb of Parkinson's and Alzheimer's Patients

(2013) Karlijn J. Doorn et al.   BRAIN PATHOLOGY

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

The APOE ε4/ε4 Genotype Potentiates Vascular Fibrin(Ogen) Deposition in Amyloid-Laden Vessels in the Brains of Alzheimer's Disease Patients

(2013) Karin Hultman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Comparison of Histological Techniques to Visualize Iron in Paraffin-embedded Brain Tissue of Patients with Alzheimer’s Disease

(2013) Sara van Duijn et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

3H-Deprenyl and 3H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain

(2013) Amelia Marutle et al.   Journal of Neuroinflammation

CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing

(2013) M. Malik et al.   JOURNAL OF NEUROSCIENCE

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

(2013) Elizabeth M Bradshaw et al.   NATURE NEUROSCIENCE

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

Neuroprotective Effect of Physical Exercise in a Mouse Model of Alzheimer’s Disease Induced by β-Amyloid1–40 Peptide

(2013) Leandro C. Souza et al.   NEUROTOXICITY RESEARCH

Hippocampal Glutamate NMDA Receptor Loss Tracks Progression in Alzheimer’s Disease: Quantitative Autoradiography in Postmortem Human Brain

(2013) Efrat Kravitz et al.   PLoS One

NG2 cells, a new trail for Alzheimer’s disease mechanisms?

(2013) Henrietta M Nielsen et al.   Acta Neuropathologica Communications

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

(2012) David H Cribbs et al.   Journal of Neuroinflammation

Immunohistochemical study of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 in the hippocampal vasculature: Pathological synergy of Alzheimer's disease and diabetes mellitus

(2012) Tony Valente et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Alterations in the histaminergic system in Alzheimer's disease: a postmortem study

(2012) Ling Shan et al.   NEUROBIOLOGY OF AGING

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease

(2011) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

(2011) Anna Carrano et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuroinflammation in Alzheimer's disease wanes with age

(2011) Jeroen JM Hoozemans et al.   Journal of Neuroinflammation

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism

(2011) Gunjan Dhawan et al.   NEUROBIOLOGY OF AGING

Region-specific distribution of β-amyloid peptide and cytokine expression in TgCRND8 mice

(2011) Keran Ma et al.   NEUROSCIENCE LETTERS

Molecular Insights into the Pathogenesis of Alzheimer's Disease and Its Relationship to Normal Aging

(2011) Alexei A. Podtelezhnikov et al.   PLoS One

Converging Perturbed Microvasculature and Microglial Clusters Characterize Alzheimer Disease Brain

(2010) N. Jantaratnotai et al.   Current Alzheimer Research

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease

(2009) Wolfgang J. Streit et al.   ACTA NEUROPATHOLOGICA

Autoantibodies against β-amyloid are common in Alzheimer's disease and help control plaque burden

(2009) Alexander Kellner et al.   ANNALS OF NEUROLOGY

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Evidence of angiogenic vessels in Alzheimer’s disease

(2009) Brinda S. Desai et al.   JOURNAL OF NEURAL TRANSMISSION

Expression and localization of lactotransferrin messenger RNA in the cortex of Alzheimer's disease

(2009) Li An et al.   NEUROSCIENCE LETTERS

Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

(2008) Lars Bertram et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Heterogeneity of white matter hyperintensities in Alzheimer's disease: post-mortem quantitative MRI and neuropathology

(2008) A. A. Gouw et al.   BRAIN

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

(2008) Sung-Chun Tang et al.   EXPERIMENTAL NEUROLOGY

Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity

(2008) Kryslaine O. Lopes et al.   GLIA

A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain

(2008) Jae K. Ryu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease

(2008) Kathryn J Bryan et al.   Molecular Neurodegeneration

Multiple sclerosis and Alzheimer's disease

(2007) Assunta Dal Bianco et al.   ANNALS OF NEUROLOGY

The role of inflammation in CNS injury and disease

(2006) Sian-Marie Lucas et al.   BRITISH JOURNAL OF PHARMACOLOGY