Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease

(2010) Lisa Mosconi et al.   Annals of the New York Academy of Sciences

How does diabetes accelerate Alzheimer disease pathology?

(2010) Catrina Sims-Robinson et al.   Nature Reviews Neurology

Mechanisms of tau-induced neurodegeneration

(2009) Khalid Iqbal et al.   ACTA NEUROPATHOLOGICA

Dysregulation of Insulin Signaling, Glucose Transporters, O -GlcNAcylation, and Phosphorylation of Tau and Neurofilaments in the Brain

(2009) Yanqiu Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

(2009) F. Liu et al.   BRAIN

Chronic β-AR activation-induced calpain activation and impaired eNOS–Akt signaling mediates cardiac injury in ovariectomized female rats

(2009) Md. Shenuarin Bhuiyan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Brain glucose transporters,O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer’s disease

(2009) Ying Liu et al.   JOURNAL OF NEUROCHEMISTRY

The Insulin/Akt Signaling Pathway Is Targeted by Intracellular β-Amyloid

(2009) Han-Kyu Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Deficiency of a β-arrestin-2 signal complex contributes to insulin resistance

(2009) Bing Luan et al.   NATURE

Diabetes, microvascular pathology and Alzheimer disease

(2009) Raj N. Kalaria   Nature Reviews Neurology

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

(2009) Fernanda G. De Felice et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin Signaling in Sporadic Alzheimer's Disease

(2009) F.-F. Liao et al.   Science Signaling

RETRACTED: Intranasal insulin prevents cognitive decline, cerebral atrophy and white matter changes in murine type I diabetic encephalopathy

(2008)   BRAIN

Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies

(2008) Kyriaki Gerozissis   EUROPEAN JOURNAL OF PHARMACOLOGY

Calpain inhibition induces activation of the distinct signalling pathways and cell migration in human monocytes

(2008) Haruyoshi Noma et al.   IMMUNOLOGY

Wild-Type But Not FAD Mutant Presenilin-1 Prevents Neuronal Degeneration by Promoting Phosphatidylinositol 3-Kinase Neuroprotective Signaling

(2008) L. Baki et al.   JOURNAL OF NEUROSCIENCE

Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: Parallels with Alzheimer's disease and correction by insulin

(2008) C.G. Jolivalt et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Calpain-mediated truncation of GSK-3 in post-mortem brain samples

(2008) Paloma Goñi-Oliver et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

(2008) Xiaoyong Yang et al.   NATURE