The enigmatic endosome – sorting the ins and outs of endocytic trafficking

Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic Perspectives

(2018) Jin-Sung Park et al.   Current Neurology and Neuroscience Reports

ESCRT-dependent cargo sorting at multivesicular endosomes

(2018) E.B. Frankel et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Endosomal “sort” of signaling control: The role of ESCRT machinery in regulation of receptor-mediated signaling pathways

(2018) Ewelina Szymanska et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tying trafficking to fusion and fission at the mighty mitochondria

(2018) Trey Farmer et al.   TRAFFIC

Endosomal receptor trafficking: Retromer and beyond

(2018) Jing Wang et al.   TRAFFIC

Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria

(2018) FoSheng Hsu et al.   eLife

Control of mitochondrial homeostasis by endocytic regulatory proteins

(2017) Trey Farmer et al.   JOURNAL OF CELL SCIENCE

New insights into autophagosome–lysosome fusion

(2017) Shuhei Nakamura et al.   JOURNAL OF CELL SCIENCE

Rab GTPases: master regulators that establish the secretory and endocytic pathways

(2017) Suzanne R. Pfeffer   MOLECULAR BIOLOGY OF THE CELL

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling

(2017) Kerrie E. McNally et al.   NATURE CELL BIOLOGY

Visualizing endocytic recycling and trafficking in live neurons by subdiffractional tracking of internalized molecules

(2017) Merja Joensuu et al.   Nature Protocols

SNARE proteins in membrane trafficking

(2017) Tuanlao Wang et al.   TRAFFIC

Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery

(2017) Liliane Christ et al.   TRENDS IN BIOCHEMICAL SCIENCES

Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos

(2017) E. B. Frankel et al.   Nature Communications

EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides

(2016) Kriti Bahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms and functions of lysosome positioning

(2016) Jing Pu et al.   JOURNAL OF CELL SCIENCE

The endocytic recycling compartment maintains cargo segregation acquired upon exit from the sorting endosome

(2016) Shuwei Xie et al.   MOLECULAR BIOLOGY OF THE CELL

Multiple dynamin family members collaborate to drive mitochondrial division

(2016) Jason E. Lee et al.   NATURE

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus

(2016) Seongju Lee et al.   Nature Communications

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

(2016) Paulina Bartuzi et al.   Nature Communications

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

(2015) Christine A. Phillips-Krawczak et al.   MOLECULAR BIOLOGY OF THE CELL

EARP is a multisubunit tethering complex involved in endocytic recycling

(2015) Christina Schindler et al.   NATURE CELL BIOLOGY

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

(2015) Quanlong Lu et al.   NATURE CELL BIOLOGY

Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes

(2015) Wenzhang Wang et al.   NATURE MEDICINE

VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function

(2015) Fu-Lei Tang et al.   Cell Reports

The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration

(2015) Yong-Bo Hu et al.   Translational Neurodegeneration

A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer

(2014) M. Gallon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane-associated cargo recycling by tubule-based endosomal sorting

(2014) Jan R.T. van Weering et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Endosome maturation, transport and functions

(2014) Cameron C. Scott et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Retromer: A Master Conductor of Endosome Sorting

(2014) C. Burd et al.   Cold Spring Harbor Perspectives in Biology

Recycling Endosome Tubule Morphogenesis from Sorting Endosomes Requires the Kinesin Motor KIF13A

(2014) Cédric Delevoye et al.   Cell Reports

Snx3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation

(2013) Caiyong Chen et al.   Cell Metabolism

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis

(2013) Sai Srinivas Panapakkam Giridharan et al.   MOLECULAR BIOLOGY OF THE CELL

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

The Rab11 Effector Protein FIP1 Regulates Adiponectin Trafficking and Secretion

(2013) Brian P. Carson et al.   PLoS One

A mechanism for retromer endosomal coat complex assembly with cargo

(2013) M. S. Harrison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

(2013) R. Ghai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Sorting Nexin 17-Binding Domain Within the LRP1 Cytoplasmic Tail Mediates Receptor Recycling Through the Basolateral Sorting Endosome

(2013) Pamela Farfán et al.   TRAFFIC

Retromer-mediated endosomal protein sorting: all WASHed up!

(2013) Matthew N.J. Seaman et al.   TRENDS IN CELL BIOLOGY

Lipid Sorting and Multivesicular Endosome Biogenesis

(2013) C. Bissig et al.   Cold Spring Harbor Perspectives in Biology

SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways

(2012) Florian Steinberg et al.   JOURNAL OF CELL BIOLOGY

Interplay between Rab35 and Arf6 controls cargo recycling to coordinate cell adhesion and migration

(2012) P. D. Allaire et al.   JOURNAL OF CELL SCIENCE

cPLA2α and EHD1 interact and regulate the vesiculation of cholesterol-rich, GPI-anchored, protein-containing endosomes

(2012) Bishuang Cai et al.   MOLECULAR BIOLOGY OF THE CELL

Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromer

(2012) Da Jia et al.   MOLECULAR BIOLOGY OF THE CELL

Rab GTPase regulation of retromer-mediated cargo export during endosome maturation

(2012) Ting-Ting Liu et al.   MOLECULAR BIOLOGY OF THE CELL

A family business: stem cell progeny join the niche to regulate homeostasis

(2012) Ya-Chieh Hsu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SNX12 Role in Endosome Membrane Transport

(2012) Véronique Pons et al.   PLoS One

Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis

(2012) D. M. Navaroli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retromer Guides STxB and CD8-M6PR from Early to Recycling Endosomes, EHD1 Guides STxB from Recycling Endosome to Golgi

(2012) Jenna E. McKenzie et al.   TRAFFIC

Rabankyrin-5 Interacts with EHD1 and Vps26 to Regulate Endocytic Trafficking and Retromer Function

(2012) Jing Zhang et al.   TRAFFIC

A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease

(2011) Alexander Zimprich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

VPS35 Mutations in Parkinson Disease

(2011) Carles Vilariño-Güell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Recruitment of the endosomal WASH complex is mediated by the extended ‘tail’ of Fam21 binding to the retromer protein Vps35

(2011) Michael E. Harbour et al.   BIOCHEMICAL JOURNAL

UBAP1 Is a Component of an Endosome-Specific ESCRT-I Complex that Is Essential for MVB Sorting

(2011) Flavia Stefani et al.   CURRENT BIOLOGY

Regulation of Synaptic Vesicle Budding and Dynamin Function by an EHD ATPase

(2011) J. Jakobsson et al.   JOURNAL OF NEUROSCIENCE

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

(2011) Paul Temkin et al.   NATURE CELL BIOLOGY

MICAL-L1 is a Tubular Endosomal Membrane Hub that Connects Rab35 and Arf6 With Rab8a

(2011) Juliati Rahajeng et al.   TRAFFIC

Identification of the Switch in Early-to-Late Endosome Transition

(2010) Dmitry Poteryaev et al.   CELL

Vps35 Mediates Vesicle Transport between the Mitochondria and Peroxisomes

(2010) Emélie Braschi et al.   CURRENT BIOLOGY

Mechanism for the Selective Interaction of C-terminal Eps15 Homology Domain Proteins with Specific Asn-Pro-Phe-containing Partners

(2010) Fabien Kieken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Collapsin Response Mediator Protein-2 (Crmp2) Regulates Trafficking by Linking Endocytic Regulatory Proteins to Dynein Motors

(2010) Juliati Rahajeng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

(2010) Benjamin E.L. Lauffer et al.   JOURNAL OF CELL BIOLOGY

EHBP-1 Functions with RAB-10 during Endocytic Recycling in Caenorhabditis elegans

(2010) Anbing Shi et al.   MOLECULAR BIOLOGY OF THE CELL

The Late Endosome is Essential for mTORC1 Signaling

(2010) Rory J. Flinn et al.   MOLECULAR BIOLOGY OF THE CELL

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

(2010) D. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EHD proteins: key conductors of endocytic transport

(2010) Naava Naslavsky et al.   TRENDS IN CELL BIOLOGY

Sorting nexin 8 regulates endosome-to-Golgi transport

(2009) Anne Berit Dyve et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bis(monoacylglycero)phosphate Forms Stable Small Lamellar Vesicle Structures: Insights into Vesicular Body Formation in Endosomes

(2009) Thomas E. Frederick et al.   BIOPHYSICAL JOURNAL

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

Annexin A2-Dependent Polymerization of Actin Mediates Endosome Biogenesis

(2009) Etienne Morel et al.   DEVELOPMENTAL CELL

F-BAR Proteins of the Syndapin Family Shape the Plasma Membrane and Are Crucial for Neuromorphogenesis

(2009) E. Dharmalingam et al.   JOURNAL OF NEUROSCIENCE

MICAL-L1 Links EHD1 to Tubular Recycling Endosomes and Regulates Receptor Recycling

(2009) Mahak Sharma et al.   MOLECULAR BIOLOGY OF THE CELL

Pathways and mechanisms of endocytic recycling

(2009) Barth D. Grant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex

(2009) M. R. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insight into the interaction of proteins containing NPF, DPF, and GPF motifs with the C-terminal EH-domain of EHD1

(2009) Fabien Kieken et al.   PROTEIN SCIENCE

Retromer

(2008) Juan S Bonifacino et al.   CURRENT OPINION IN CELL BIOLOGY

The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling

(2008) E. Schonteich et al.   JOURNAL OF CELL SCIENCE

Polarized Traffic of LRP1 Involves AP1B and SNX17 Operating on Y-dependent Sorting Motifs in Different Pathways

(2008) Maribel Donoso et al.   MOLECULAR BIOLOGY OF THE CELL

Different Microtubule Motors Move Early and Late Endocytic Compartments

(2008) Sylvain Loubéry et al.   TRAFFIC

A Role for EHD4 in the Regulation of Early Endosomal Transport

(2008) Mahak Sharma et al.   TRAFFIC

Hrs and SNX3 Functions in Sorting and Membrane Invagination within Multivesicular Bodies

(2008) Véronique Pons et al.   PLOS BIOLOGY