Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N

Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration

(2014) E. Tsika et al.   HUMAN MOLECULAR GENETICS

RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation

(2014) C. L. Freeman et al.   JOURNAL OF CELL SCIENCE

VPS35 Parkinson’s disease phenotype resembles the sporadic disease

(2014) Walter Struhal et al.   JOURNAL OF NEURAL TRANSMISSION

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

(2014) Loukia Parisiadou et al.   NATURE NEUROSCIENCE

Palmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticity

(2014) G Stefano Brigidi et al.   NATURE NEUROSCIENCE

Retromer Mediates a Discrete Route of Local Membrane Delivery to Dendrites

(2014) Regina Wai-Yan Choy et al.   NEURON

Sorting Nexin 27 regulates basal and activity-dependent trafficking of AMPARs

(2014) N. K. Hussain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling

(2014) V. A. Morais et al.   SCIENCE

Pathogenic Mutation in VPS35 Impairs Its Protection against MPP+ Cytotoxicity

(2013) Fangfang Bi et al.   International Journal of Biological Sciences

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

Advances in the genetics of Parkinson disease

(2013) Joanne Trinh et al.   Nature Reviews Neurology

RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk

(2013) David A. MacLeod et al.   NEURON

Retromer-mediated endosomal protein sorting: all WASHed up!

(2013) Matthew N.J. Seaman et al.   TRENDS IN CELL BIOLOGY

Frequency of the D620N Mutation in VPS35 in Parkinson Disease

(2012) Kishore R. Kumar et al.   ARCHIVES OF NEUROLOGY

Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules

(2012) Jan R T van Weering et al.   EMBO JOURNAL

RAB-6.2 and the retromer regulate glutamate receptor recycling through a retrograde pathway

(2012) Donglei Zhang et al.   JOURNAL OF CELL BIOLOGY

Opposing Roles of Synaptic and Extrasynaptic NMDA Receptor Signaling in Cocultured Striatal and Cortical Neurons

(2012) A. M. Kaufman et al.   JOURNAL OF NEUROSCIENCE

Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice

(2012) Austen J. Milnerwood et al.   NEUROBIOLOGY OF DISEASE

The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport

(2012) Akhil Bhalla et al.   NEUROBIOLOGY OF DISEASE

LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis

(2012) Samer Matta et al.   NEURON

Using FLIM-FRET to Measure Conformational Changes of Transglutaminase Type 2 in Live Cells

(2012) Nicholas S. Caron et al.   PLoS One

VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1

(2012) C.-L. Wang et al.   Biology Open

VPS35 Mutations in Parkinson Disease

(2011) Carles Vilariño-Güell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology

(2011) Lei Wen et al.   JOURNAL OF CELL BIOLOGY

Progranulin Deficiency Decreases Gross Neural Connectivity But Enhances Transmission at Individual Synapses

(2011) L. Tapia et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells

(2011) P. Seibler et al.   JOURNAL OF NEUROSCIENCE

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease

(2011) Sonja Kriks et al.   NATURE

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

(2011) Paul Temkin et al.   NATURE CELL BIOLOGY

Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal Dementia Protein, Progranulin

(2010) Fenghua Hu et al.   NEURON

AMPA Receptor Incorporation into Synapses during LTP: The Role of Lateral Movement and Exocytosis

(2009) Hiroshi Makino et al.   NEURON

Communication Between the Synapse and the Nucleus in Neuronal Development, Plasticity, and Disease

(2008) Sonia Cohen et al.   Annual Review of Cell and Developmental Biology

Retromer

(2008) Juan S Bonifacino et al.   CURRENT OPINION IN CELL BIOLOGY

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A  accumulation

(2008) A. Muhammad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure and Function of the Retromer Protein Complex

(2008) Brett M. Collins   TRAFFIC