Neuronal activity recruits the CRTC1/CREB axis to drive transcription-dependent autophagy for maintaining late-phase LTD

NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95

(2021) Benjamin Compans et al.   Nature Communications

Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling

(2020) Hongmei Shen et al.   Nature Communications

Autophagy Is Required for Memory Formation and Reverses Age-Related Memory Decline

(2019) Mélissa Glatigny et al.   CURRENT BIOLOGY

Cellular quality control by the ubiquitin-proteasome system and autophagy

(2019) Christian Pohl et al.   SCIENCE

Autophagy Enhances Memory Erasure through Synaptic Destabilization

(2018) Mohammad Shehata et al.   JOURNAL OF NEUROSCIENCE

Calmodulin shuttling mediates cytonuclear signaling to trigger experience-dependent transcription and memory

(2018) Samuel M. Cohen et al.   Nature Communications

Autophagy in the presynaptic compartment in health and disease

(2017) Vinoy Vijayan et al.   JOURNAL OF CELL BIOLOGY

A role for autophagy in long-term spatial memory formation in male rodents

(2017) Michael J. Hylin et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Identification of functional farnesoid X receptors in brain neurons

(2016) Chao Huang et al.   FEBS LETTERS

Ubiquitin-Proteasome System Inhibition Promotes Long-Term Depression and Synaptic Tagging/Capture

(2015) Qin Li et al.   CEREBRAL CORTEX

Rescue of impaired late–phase long-term depression in a tau transgenic mouse model

(2015) Tariq Ahmed et al.   NEUROBIOLOGY OF AGING

γCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression

(2014) Huan Ma et al.   CELL

Transcriptional regulation of autophagy by an FXR–CREB axis

(2014) Sunmi Seok et al.   NATURE

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Region-Specific Activation of CRTC1-CREB Signaling Mediates Long-Term Fear Memory

(2014) Mio Nonaka et al.   NEURON

The Regulation of Transcription in Memory Consolidation

(2014) Cristina M. Alberini et al.   Cold Spring Harbor Perspectives in Biology

Learning-facilitated long-term depression requires activation of the immediate early gene, c-fos, and is transcription dependent

(2013) Anne Kemp et al.   BEHAVIOURAL BRAIN RESEARCH

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Activity-Dependent Transport of the Transcriptional Coactivator CRTC1 from Synapse to Nucleus

(2012) Toh Hean Ch'ng et al.   CELL

CaV1 and CaV2 Channels Engage Distinct Modes of Ca2+ Signaling to Control CREB-Dependent Gene Expression

(2012) Damian G. Wheeler et al.   CELL

Spatial Parkin Translocation and Degradation of Damaged Mitochondria via Mitophagy in Live Cortical Neurons

(2012) Qian Cai et al.   CURRENT BIOLOGY

Neuronal Stimulation Induces Autophagy in Hippocampal Neurons That Is Involved in AMPA Receptor Degradation after Chemical Long-Term Depression

(2012) M. Shehata et al.   JOURNAL OF NEUROSCIENCE

The JAK/STAT Pathway Is Involved in Synaptic Plasticity

(2012) Céline S. Nicolas et al.   NEURON

Regulation of Presynaptic Neurotransmission by Macroautophagy

(2012) Daniela Hernandez et al.   NEURON

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

(2011) Judith Y. Altarejos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization

(2010) Zheng Li et al.   CELL

LTP- and LTD-inducing stimulations cause opposite changes in arc/arg3.1 mRNA level in hippocampal area CA1 in vivo

(2010) Eser Yilmaz-Rastoder et al.   HIPPOCAMPUS

SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cells

(2010) Constance Smith-Hicks et al.   NATURE NEUROSCIENCE

Long-term depression in the CNS

(2010) Graham L. Collingridge et al.   NATURE REVIEWS NEUROSCIENCE

Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission

(2010) Ann Van der Jeugd et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

DREAM (Downstream Regulatory Element Antagonist Modulator) contributes to synaptic depression and contextual fear memory

(2010) Long-Jun Wu et al.   Molecular Brain

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

(2009) Zhenyu Yue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

N-methyl-d-aspartate receptor- and metabotropic glutamate receptor-dependent long-term depression are differentially regulated by the ubiquitin-proteasome system

(2009) Ami Citri et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

TORC1 Regulates Activity-Dependent CREB-Target Gene Transcription and Dendritic Growth of Developing Cortical Neurons

(2009) S. Li et al.   JOURNAL OF NEUROSCIENCE

A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors

(2009) Samarjit Bhattacharyya et al.   NATURE NEUROSCIENCE

Stability of surface NMDA receptors controls synaptic and behavioral adaptations to amphetamine

(2009) Li-Min Mao et al.   NATURE NEUROSCIENCE

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Molecular Dissociation of the Role of PSD-95 in Regulating Synaptic Strength and LTD

(2008) Weifeng Xu et al.   NEURON

Synaptic Protein Degradation Underlies Destabilization of Retrieved Fear Memory

(2008) S.-H. Lee et al.   SCIENCE