Unconventional secretion of FABP4 by endosomes and secretory lysosomes

A diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1

(2017) David Cruz-Garcia et al.   JOURNAL OF CELL BIOLOGY

The Lysosome as a Regulatory Hub

(2016) Rushika M. Perera et al.   Annual Review of Cell and Developmental Biology

The position of lysosomes within the cell determines their luminal pH

(2016) Danielle E. Johnson et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

(2016) Xiaoyan Robert Bao et al.   eLife

Metabolic functions of FABPs—mechanisms and therapeutic implications

(2015) Gökhan S. Hotamisligil et al.   Nature Reviews Endocrinology

Circulating adipocyte fatty acid-binding protein induces insulin resistance in micein vivo

(2015) Susan Kralisch et al.   Obesity

Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes

(2015) M. Furkan Burak et al.   Science Translational Medicine

Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

(2015) Min Zhang et al.   eLife

Remodeling of secretory compartments creates CUPS during nutrient starvation

(2014) David Cruz-Garcia et al.   JOURNAL OF CELL BIOLOGY

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity

(2014) Meric Erikci Ertunc et al.   JOURNAL OF LIPID RESEARCH

FABP4 is secreted from adipocytes by adenyl cyclase-PKA- and guanylyl cyclase-PKG-dependent lipolytic mechanisms

(2014) Tomohiro Mita et al.   Obesity

Lysosomal Adaptation: How the Lysosome Responds to External Cues

(2014) C. Settembre et al.   Cold Spring Harbor Perspectives in Biology

Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

(2014) Lindsay E. Wu et al.   Molecular Metabolism

A favorable effect of hydroxychloroquine on glucose and lipid metabolism beyond its anti-inflammatory role

(2014) Mirella P. Hage et al.   Therapeutic Advances in Endocrinology and Metabolism

Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production

(2013) Haiming Cao et al.   Cell Metabolism

Unconventional protein secretion: an evolving mechanism

(2013) Vivek Malhotra   EMBO JOURNAL

Chloroquine: Modes of action of an undervalued drug

(2013) Rodolfo Thomé et al.   IMMUNOLOGY LETTERS

Adipocyte fatty acid-binding protein is released from adipocytes by a non-conventional mechanism

(2013) S Kralisch et al.   INTERNATIONAL JOURNAL OF OBESITY

Calcium-dependent release of adipocyte fatty acid binding protein from human adipocytes

(2013) I Schlottmann et al.   INTERNATIONAL JOURNAL OF OBESITY

Diversity in unconventional protein secretion

(2013) Catherine Rabouille et al.   JOURNAL OF CELL SCIENCE

FABP4 Induces Vascular Smooth Muscle Cell Proliferation and Migration through a MAPK-Dependent Pathway

(2013) Josefa Girona et al.   PLoS One

Unconventional Secretion, Unconventional Solutions

(2013) M. Zhang et al.   SCIENCE

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

(2013) Liang Ge et al.   eLife

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Hydroxychloroquine Use and Decreased Risk of Diabetes in Rheumatoid Arthritis Patients

(2012) Androniki Bili et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Hydroxychloroquine reduces low-density lipoprotein cholesterol levels in systemic lupus erythematosus: a longitudinal evaluation of the lipid-lowering effect

(2012) E Cairoli et al.   LUPUS

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Aldo-keto reductase family 1, member B10 is secreted through a lysosome-mediated non-classical pathway

(2011) Di-xian Luo et al.   BIOCHEMICAL JOURNAL

Hydroxychloroquine: From Malaria to Autoimmunity

(2011) Ilan Ben-Zvi et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Unconventional secretion: a stress on GRASP

(2011) Fabrizio Giuliani et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion

(2011) Caroline Bruns et al.   JOURNAL OF CELL BIOLOGY

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Pathways of unconventional protein secretion

(2010) Walter Nickel   CURRENT OPINION IN BIOTECHNOLOGY

Unconventional secretion of Acb1 is mediated by autophagosomes

(2010) Juan M. Duran et al.   JOURNAL OF CELL BIOLOGY

Unconventional secretion ofPichia pastorisAcb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation

(2010) Ravi Manjithaya et al.   JOURNAL OF CELL BIOLOGY

Adipocyte Fatty Acid–Binding Protein Suppresses Cardiomyocyte Contraction

(2009) Valéria Lamounier-Zepter et al.   CIRCULATION RESEARCH

Mechanisms of regulated unconventional protein secretion

(2009) Walter Nickel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles

(2009) A. J. Schindler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA