Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum

Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy

(2020) Ori J Lieberman et al.   eLife

The Journey of the Synaptic Autophagosome: A Cell Biological Perspective

(2020) Sarah E. Hill et al.   NEURON

Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling

(2020) Hongmei Shen et al.   Nature Communications

Light-activated ROS production induces synaptic autophagy

(2019) Sheila Hoffmann et al.   JOURNAL OF NEUROSCIENCE

Autophagy in Neurons

(2019) Andrea K.H. Stavoe et al.   Annual Review of Cell and Developmental Biology

WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death

(2019) Huida Wan et al.   Autophagy

VAP‐SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function

(2019) Feline W Lindhout et al.   EMBO JOURNAL

Axonal transport: Driving synaptic function

(2019) Pedro Guedes-Dias et al.   SCIENCE

SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals

(2019) Maria Andres-Alonso et al.   Nature Communications

Presynaptic endoplasmic reticulum and neurotransmission

(2019) Ilya Bezprozvanny et al.   CELL CALCIUM

Protein Quality Control of the Endoplasmic Reticulum and Ubiquitin–Proteasome-Triggered Degradation of Aberrant Proteins: Yeast Pioneers the Path

(2018) Nicole Berner et al.   Annual Review of Biochemistry

Presynaptic endocytic factors in autophagy and neurodegeneration

(2018) Domenico Azarnia Tehran et al.   CURRENT OPINION IN NEUROBIOLOGY

Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease

(2018) Evanthia Nanou et al.   NEURON

Regulation and Roles of Autophagy at Synapses

(2018) Vassiliki Nikoletopoulou et al.   TRENDS IN CELL BIOLOGY

Atlastins remodel the endoplasmic reticulum for selective autophagy

(2018) Jin Rui Liang et al.   JOURNAL OF CELL BIOLOGY

ER-phagy at a glance

(2018) Paolo Grumati et al.   JOURNAL OF CELL SCIENCE

Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis

(2018) Diego E. Hernández et al.   JOURNAL OF CELL SCIENCE

Autophagy in the presynaptic compartment in health and disease

(2017) Vinoy Vijayan et al.   JOURNAL OF CELL BIOLOGY

Double-Nanodomain Coupling of Calcium Channels, Ryanodine Receptors, and BK Channels Controls the Generation of Burst Firing

(2017) Tomohiko Irie et al.   NEURON

Axonal Endoplasmic Reticulum Ca 2+ Content Controls Release Probability in CNS Nerve Terminals

(2017) Jaime de Juan-Sanz et al.   NEURON

Bassoon Controls Presynaptic Autophagy through Atg5

(2017) Nathan D. Okerlund et al.   NEURON

Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration

(2017) Natalia L. Kononenko et al.   Nature Communications

The effects of proteasomal inhibition on synaptic proteostasis

(2016) Vicky Hakim et al.   EMBO JOURNAL

Autophagy core machinery: overcoming spatial barriers in neurons

(2016) Aileen R. Ariosa et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Compartment-Specific Regulation of Autophagy in Primary Neurons

(2016) Sandra Maday et al.   JOURNAL OF NEUROSCIENCE

A phosphoinositide conversion mechanism for exit from endosomes

(2016) Katharina Ketel et al.   NATURE

A LRRK2-Dependent EndophilinA Phosphoswitch Is Critical for Macroautophagy at Presynaptic Terminals

(2016) Sandra-Fausia Soukup et al.   NEURON

Shaping the Endoplasmic Reticulum into a Social Network

(2016) Hong Zhang et al.   TRENDS IN CELL BIOLOGY

Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System

(2016) John D. Murdoch et al.   Cell Reports

Microscopy Image Browser: A Platform for Segmentation and Analysis of Multidimensional Datasets

(2016) Ilya Belevich et al.   PLOS BIOLOGY

Form Follows Function: The Importance of Endoplasmic Reticulum Shape

(2015) L.M. Westrate et al.   Annual Review of Biochemistry

Control of Autophagosome Axonal Retrograde Flux by Presynaptic Activity Unveiled Using Botulinum Neurotoxin Type A

(2015) Tong Wang et al.   JOURNAL OF NEUROSCIENCE

Regulation of endoplasmic reticulum turnover by selective autophagy

(2015) Aliaksandr Khaminets et al.   NATURE

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

(2014) Ruzica Bago et al.   BIOCHEMICAL JOURNAL

Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated Pathway

(2014) Sandra Maday et al.   DEVELOPMENTAL CELL

Synaptic vesicle recycling: steps and principles

(2014) S. O. Rizzoli   EMBO JOURNAL

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

(2014) Ghazaleh Ashrafi et al.   JOURNAL OF CELL BIOLOGY

Ryanodine receptors: physiological function and deregulation in Alzheimer disease

(2014) Dolores Del Prete et al.   Molecular Neurodegeneration

Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes

(2014) Shinya Honda et al.   Nature Communications

PICALM modulates autophagy activity and tau accumulation

(2014) Kevin Moreau et al.   Nature Communications

Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation

(2013) Clarissa L Waites et al.   EMBO JOURNAL

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Visualizing presynaptic function

(2013) Ege T Kavalali et al.   NATURE NEUROSCIENCE

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

α-synuclein levels affect autophagosome numbers in vivo and modulate Huntington disease pathology

(2012) Silvia Corrochano et al.   Autophagy

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

Neuronal Stimulation Induces Autophagy in Hippocampal Neurons That Is Involved in AMPA Receptor Degradation after Chemical Long-Term Depression

(2012) M. Shehata et al.   JOURNAL OF NEUROSCIENCE

Disrupted Autophagy Leads to Dopaminergic Axon and Dendrite Degeneration and Promotes Presynaptic Accumulation of  -Synuclein and LRRK2 in the Brain

(2012) L. G. Friedman et al.   JOURNAL OF NEUROSCIENCE

Molecular machines governing exocytosis of synaptic vesicles

(2012) Reinhard Jahn et al.   NATURE

Protein scaffolds in the coupling of synaptic exocytosis and endocytosis

(2011) Volker Haucke et al.   NATURE REVIEWS NEUROSCIENCE

Molecular and cellular mechanisms of excitotoxic neuronal death

(2010) Yan Wang et al.   APOPTOSIS

Contributions of SERCA pump and ryanodine-sensitive stores to presynaptic residual Ca2+

(2010) Chessa S. Scullin et al.   CELL CALCIUM

Protein homeostasis and synaptic plasticity

(2010) Iván J Cajigas et al.   EMBO JOURNAL

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

(2009) Sebastian Schuck et al.   JOURNAL OF CELL BIOLOGY

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

The probability of neurotransmitter release: variability and feedback control at single synapses

(2009) Tiago Branco et al.   NATURE REVIEWS NEUROSCIENCE

Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease

(2008) B. Ravikumar et al.   JOURNAL OF CELL SCIENCE

Multiple Roles of Calcium Ions in the Regulation of Neurotransmitter Release

(2008) Erwin Neher et al.   NEURON

Use-dependent amplification of presynaptic Ca2+ signaling by axonal ryanodine receptors at the hippocampal mossy fiber synapse

(2008) H. Shimizu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA