Tubulin Polymerization-promoting Protein (TPPP/p25α) Promotes Unconventional Secretion of α-Synuclein through Exophagy by Impairing Autophagosome-Lysosome Fusion
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Title
Tubulin Polymerization-promoting Protein (TPPP/p25α) Promotes Unconventional Secretion of α-Synuclein through Exophagy by Impairing Autophagosome-Lysosome Fusion
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 288, Issue 24, Pages 17313-17335
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2013-04-30
DOI
10.1074/jbc.m112.401174
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Note: Only part of the references are listed.- Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders
- (2012) Anja Schneider et al. CELL AND TISSUE RESEARCH
- Mechanism of Evenness Interrupted (Evi)-Exosome Release at Synaptic Boutons
- (2012) Kate Koles et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
- (2011) Christian Hansen et al. JOURNAL OF CLINICAL INVESTIGATION
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of α-Synuclein
- (2011) Takafumi Hasegawa et al. PLoS One
- HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
- (2010) Joo-Yong Lee et al. EMBO JOURNAL
- Lysosomal Degradation of α-Synucleinin Vivo
- (2010) Sally K. Mak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rab27a Negatively Regulates Phagocytosis by Prolongation of the Actin-coating Stage around Phagosomes
- (2010) Kunio Yokoyama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TPPP/p25 Promotes Tubulin Acetylation by Inhibiting Histone Deacetylase 6
- (2010) Natália Tőkési et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase
- (2010) You-Tong Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Unconventional secretion of Acb1 is mediated by autophagosomes
- (2010) Juan M. Duran et al. JOURNAL OF CELL BIOLOGY
- α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
- (2010) Ashley R. Winslow et al. JOURNAL OF CELL BIOLOGY
- FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport
- (2010) Serhiy Pankiv et al. JOURNAL OF CELL BIOLOGY
- Pathogenic Lysosomal Depletion in Parkinson's Disease
- (2010) B. Dehay et al. JOURNAL OF NEUROSCIENCE
- Cell-Produced -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
- (2010) E. Emmanouilidou et al. JOURNAL OF NEUROSCIENCE
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
- (2010) Masaaki Komatsu et al. NATURE CELL BIOLOGY
- Selective autophagy: ubiquitin-mediated recognition and beyond
- (2010) Claudine Kraft et al. NATURE CELL BIOLOGY
- The origin of the autophagosomal membrane
- (2010) Sharon A. Tooze et al. NATURE CELL BIOLOGY
- Autophagy: a broad role in unconventional protein secretion?
- (2010) Ravi Manjithaya et al. TRENDS IN CELL BIOLOGY
- Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless
- (2009) Ceren Korkut et al. CELL
- Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
- (2009) Martin Gamerdinger et al. EMBO JOURNAL
- Interaction with synphilin-1 promotes inclusion formation of α-synuclein: mechanistic insights and pathological implication
- (2009) Yuan-Yuan Xie et al. FASEB JOURNAL
- α-Synuclein Aggregation and Ser-129 Phosphorylation-dependent Cell Death in Oligodendroglial Cells
- (2009) Christine L. Kragh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rab27a and Rab27b control different steps of the exosome secretion pathway
- (2009) Matias Ostrowski et al. NATURE CELL BIOLOGY
- Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity
- (2009) Esti Yeger-Lotem et al. NATURE GENETICS
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy and multivesicular bodies: two closely related partners
- (2008) C M Fader et al. CELL DEATH AND DIFFERENTIATION
- The expression of tubulin polymerization promoting protein TPPP/p25α is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress
- (2008) Olaf Goldbaum et al. GLIA
- Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells
- (2008) Tereza Vogiatzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
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