Blood-Brain Barrier Disruption by Lipopolysaccharide and Sepsis-Associated Encephalopathy
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Title
Blood-Brain Barrier Disruption by Lipopolysaccharide and Sepsis-Associated Encephalopathy
Authors
Keywords
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Journal
Frontiers in Cellular and Infection Microbiology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-11-04
DOI
10.3389/fcimb.2021.768108
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Note: Only part of the references are listed.- Gold nanoparticles reduce inflammation in cerebral microvessels of mice with sepsis
- (2021) Davide Di Bella et al. JOURNAL OF NANOBIOTECHNOLOGY
- Isorhynchophylline ameliorates paraquat-induced acute kidney injury by attenuating oxidative stress and mitochondrial damage via regulating toll-interacting expression
- (2021) Qiang Zheng et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain
- (2020) Libo Su et al. CELL DEATH AND DIFFERENTIATION
- Mesenchymal Stromal Cells Protect the Blood-Brain Barrier, Reduce Astrogliosis, and Prevent Cognitive and Behavioral Alterations in Surviving Septic Mice
- (2020) Adriano Y. O. Silva et al. CRITICAL CARE MEDICINE
- Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro
- (2020) Madeleine Goeritzer et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tight junctions in the blood–brain barrier promote edema formation and infarct size in stroke – Ambivalent effects of sealing proteins
- (2020) Lars Winkler et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Sepsis-associated encephalopathy: a vicious cycle of immunosuppression
- (2020) Chao Ren et al. Journal of Neuroinflammation
- Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy
- (2020) Bereketeab Haileselassie et al. Journal of Neuroinflammation
- Immune cell regulation of glia during CNS injury and disease
- (2020) Andrew D. Greenhalgh et al. NATURE REVIEWS NEUROSCIENCE
- Microglial activation and responses to vasculature that result from an acute LPS exposure
- (2020) John F. Bowyer et al. NEUROTOXICOLOGY
- Fenretinide attenuates lipopolysaccharide (LPS)-induced blood-brain barrier (BBB) and depressive-like behavior in mice by targeting Nrf-2 signaling
- (2020) Ting Li et al. BIOMEDICINE & PHARMACOTHERAPY
- ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs
- (2020) Yueh-Lin Tsai et al. GENES & DEVELOPMENT
- Prostaglandin E1 Improves Cerebral Microcirculation Through Activation of Endothelial NOS and GRPCH1
- (2020) Lei Liu et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- The cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo study
- (2020) Farzane Sivandzade et al. Journal of Neuroinflammation
- Prolonged Soluble Epoxide Hydrolase Reactivity in Brain Endothelial Cells Is Associated with Long Cognitive Deficits in Sepsis
- (2020) Pengfei Wang et al. MOLECULAR NEUROBIOLOGY
- CXCR2 antagonist attenuates neutrophil transmigration into brain in a murine model of LPS induced neuroinflammation
- (2020) Fengjiao Wu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Vascularized neural constructs for ex-vivo reconstitution of blood-brain barrier function
- (2020) Haibing Yue et al. BIOMATERIALS
- Glycemic control with insulin attenuates sepsis-associated encephalopathy by inhibiting glial activation via the suppression of the nuclear factor kappa B and mitogen-activated protein kinase signaling pathways in septic rats
- (2020) Chun-Ta Huang et al. BRAIN RESEARCH
- Chronic molecular hydrogen inhalation mitigates short and long-term memory loss in polymicrobial sepsis
- (2020) Aline A. Jesus et al. BRAIN RESEARCH
- Use of Intravenous Immunoglobulins in Sepsis Therapy—A Clinical View
- (2020) Dominik Jarczak et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Neuronal regulation of the blood–brain barrier and neurovascular coupling
- (2020) Luke Kaplan et al. NATURE REVIEWS NEUROSCIENCE
- 1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation InVivo and In Vitro Model
- (2020) Xingyang Yi et al. Frontiers in Pharmacology
- Astrocyte glutathione maintains endothelial barrier stability
- (2020) Sheng-Fu Huang et al. Redox Biology
- Medicinal Plant Polyphenols Attenuate Oxidative Stress and Improve Inflammatory and Vasoactive Markers in Cerebral Endothelial Cells during Hyperglycemic Condition
- (2020) Janice Taïlé et al. Antioxidants
- Dexmedetomidine attenuates sepsis-associated inflammation and encephalopathy via central α2A adrenoceptor
- (2020) Bin Mei et al. BRAIN BEHAVIOR AND IMMUNITY
- Aging influences in the blood-brain barrier permeability and cerebral oxidative stress in sepsis
- (2020) Willian Margotti et al. EXPERIMENTAL GERONTOLOGY
- Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity
- (2020) Patrick T Ronaldson et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Carbamazepine induces a bioenergetics disruption to microvascular endothelial cells from the blood-brain barrier
- (2020) Walla Alelwani et al. TOXICOLOGY LETTERS
- Immunomodulatory Effects of Diterpenes and Their Derivatives Through NLRP3 Inflammasome Pathway: A Review
- (2020) Muhammad Torequl Islam et al. Frontiers in Immunology
- Novel Intrinsic Mechanisms of Active Drug Extrusion at the Blood-Brain Barrier: Potential Targets for Enhancing Drug Delivery to the Brain?
- (2020) Wolfgang Löscher et al. Pharmaceutics
- Omarigliptin Mitigates Lipopolysaccharide-Induced Neuroinflammation and Dysfunction of the Integrity of the Blood–Brain Barrier
- (2020) Hailiang Du et al. ACS Chemical Neuroscience
- Maf1 Ameliorates Sepsis-Associated Encephalopathy by Suppressing the NF-kB/NLRP3 Inflammasome Signaling Pathway
- (2020) Shenglong Chen et al. Frontiers in Immunology
- The protective effect of walnut oil on lipopolysaccharide–induced acute intestinal injury in mice
- (2020) Fujun Miao et al. Food Science & Nutrition
- Iron Dysregulation and Inflammagens Related to Oral and Gut Health Are Central to the Development of Parkinson’s Disease
- (2020) Marthinus Janse van Vuuren et al. Biomolecules
- A combination of lycopene and human amniotic epithelial cells can ameliorate cognitive deficits and suppress neuroinflammatory signaling by choroid plexus in Alzheimer's disease rat
- (2020) Zhiguo Xu et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Sepsis associated acute kidney injury
- (2019) Jason T Poston et al. BMJ-British Medical Journal
- Omi/HtrA2 Protease Associated Cell Apoptosis Participates in Blood-Brain Barrier Dysfunction
- (2019) Yueyu Hu et al. Frontiers in Molecular Neuroscience
- Intravenous immunoglobulin in sepsis: can we find the right dose?
- (2019) Tamas Szakmany Minerva Anestesiologica
- Epidemiology and Predictors of 30-Day Readmission in Patients With Sepsis
- (2019) Shruti K. Gadre et al. CHEST
- Selective loss of cortical endothelial tight junction proteins during Alzheimer’s disease progression
- (2019) Yu Yamazaki et al. BRAIN
- Caspase-1 inhibitor exerts brain-protective effects against sepsis-associated encephalopathy and cognitive impairments in a mouse model of sepsis
- (2019) Xi-e Xu et al. BRAIN BEHAVIOR AND IMMUNITY
- Epidemiology of sepsis in Taiwan
- (2019) Yen-Jung Chen et al. MEDICINE
- Development and Cell Biology of the Blood-Brain Barrier
- (2019) Urs H. Langen et al. Annual Review of Cell and Developmental Biology
- Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss
- (2019) Angeliki M. Nikolakopoulou et al. NATURE NEUROSCIENCE
- Reduced Neuronal cAMP in the Nucleus Accumbens Damages Blood-Brain Barrier Integrity and Promotes Stress Vulnerability
- (2019) Yue Zhang et al. BIOLOGICAL PSYCHIATRY
- Walnut-Associated Fatty Acids Inhibit LPS-Induced Activation of BV-2 Microglia
- (2019) Amanda N. Carey et al. INFLAMMATION
- Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy
- (2019) Daniel S. Kikuchi et al. Journal of Neuroinflammation
- Mitochondria as multifaceted regulators of cell death
- (2019) Florian J. Bock et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL
- (2019) Jennifer R. Linden et al. PLoS Pathogens
- Astrocyte-Derived Paracrine Signals: Relevance for Neurogenic Niche Regulation and Blood–Brain Barrier Integrity
- (2019) Simona Federica Spampinato et al. Frontiers in Pharmacology
- Post-treatment With Qing-Ying-Tang, a Compound Chinese Medicine Relives Lipopolysaccharide-Induced Cerebral Microcirculation Disturbance in Mice
- (2019) Hao-Min Wang et al. Frontiers in Physiology
- Experimental sepsis-associated encephalopathy is accompanied by altered cerebral blood perfusion and water diffusion and related to changes in cyclooxygenase-2 expression and glial cell morphology but not to blood-brain barrier breakdown
- (2019) Marion Griton et al. BRAIN BEHAVIOR AND IMMUNITY
- Effects of dexmedetomidine on perioperative stress, inflammation, and immune function: systematic review and meta-analysis
- (2019) Kun Wang et al. BRITISH JOURNAL OF ANAESTHESIA
- Perfluorooctane sulfonate disrupts the blood brain barrier through the crosstalk between endothelial cells and astrocytes in mice
- (2019) Yongquan Yu et al. ENVIRONMENTAL POLLUTION
- Aluminum-induced generation of lipopolysaccharide (LPS) from the human gastrointestinal (GI)-tract microbiome-resident Bacteroides fragilis
- (2019) P.N. Alexandrov et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Dual microglia effects on blood brain barrier permeability induced by systemic inflammation
- (2019) Koichiro Haruwaka et al. Nature Communications
- Functional morphology of the blood–brain barrier in health and disease
- (2018) Stefan Liebner et al. ACTA NEUROPATHOLOGICA
- Dexmedetomidine Prevents Cognitive Decline by Enhancing Resolution of High Mobility Group Box 1 Protein–induced Inflammation through a Vagomimetic Action in Mice
- (2018) Jun Hu et al. ANESTHESIOLOGY
- Spreading depolarizations trigger caveolin-1-dependent endothelial transcytosis
- (2018) Homa Sadeghian et al. ANNALS OF NEUROLOGY
- Interferon-ɣ mediated signaling in the brain endothelium is critical for inflammation-induced aversion
- (2018) Michael Fritz et al. BRAIN BEHAVIOR AND IMMUNITY
- By Activating Akt/eNOS Bilobalide B Inhibits Autophagy and Promotes Angiogenesis Following Focal Cerebral Ischemia Reperfusion
- (2018) Yongqiu Zheng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Beclin-1-Dependent Autophagy Protects the Heart During Sepsis
- (2018) Yuxiao Sun et al. CIRCULATION
- Toll and Toll-like receptor signalling in development
- (2018) Niki Anthoney et al. DEVELOPMENT
- Kaempferol alleviates LPS-induced neuroinflammation and BBB dysfunction in mice via inhibiting HMGB1 release and down-regulating TLR4/MyD88 pathway
- (2018) Xiao Cheng et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Bacterial lipopolysaccharide-induced systemic inflammation alters perfusion of white matter-rich regions without altering flow in brain-irrigating arteries: Relationship to blood-brain barrier breakdown?
- (2018) Ibtihel Dhaya et al. JOURNAL OF NEUROIMMUNOLOGY
- Unique and shared inflammatory profiles of human brain endothelia and pericytes
- (2018) Leon C. D. Smyth et al. Journal of Neuroinflammation
- The inhibitory effect of LPS on the expression of GPR81 lactate receptor in blood-brain barrier model in vitro
- (2018) Elizaveta B. Boitsova et al. Journal of Neuroinflammation
- Novel insights into neuroinflammation: bacterial lipopolysaccharide, tumor necrosis factor α, and Ureaplasma species differentially modulate atypical chemokine receptor 3 responses in human brain microvascular endothelial cells
- (2018) Christine Silwedel et al. Journal of Neuroinflammation
- Mechanisms and treatment of organ failure in sepsis
- (2018) Christophe Lelubre et al. Nature Reviews Nephrology
- Astragaloside IV protects blood-brain barrier integrity from LPS-induced disruption via activating Nrf2 antioxidant signaling pathway in mice
- (2018) Hongli Li et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Multiple Organ Dysfunction: The Defining Syndrome of Sepsis
- (2018) Markus T. Ziesmann et al. Surgical Infections
- Interleukin 6-Mediated Endothelial Barrier Disturbances Can Be Attenuated by Blockade of the IL6 Receptor Expressed in Brain Microvascular Endothelial Cells
- (2018) Kinga G. Blecharz-Lang et al. Translational Stroke Research
- Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation
- (2018) Tuo Yang et al. Redox Biology
- A high-fat diet impairs mitochondrial biogenesis, mitochondrial dynamics, and the respiratory chain complex in rat myocardial tissues
- (2018) Dan Chen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)
- (2018) Huan-Chieh Chien et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Proof-of-Concept Study to Inhibit ABCG2- and ABCB1-Mediated Efflux Transport at the Human Blood-Brain Barrier
- (2018) Martin Bauer et al. JOURNAL OF NUCLEAR MEDICINE
- Contributions of the glycocalyx, endothelium, and extravascular compartment to the blood–brain barrier
- (2018) Nikolay Kutuzov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior
- (2018) Raleigh M. Linville et al. BIOMATERIALS
- The Role of NADPH Oxidases and Oxidative Stress in Neurodegenerative Disorders
- (2018) Anuradha Tarafdar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- FISH OIL-RICH LIPID EMULSION MODULATES NEUROINFLAMMATION AND PREVENTS LONG-TERM COGNITIVE DYSFUNCTION AFTER SEPSIS
- (2018) Amanda Della Giustina et al. NUTRITION
- Blood-Brain Barrier: From Physiology to Disease and Back
- (2018) Melanie D. Sweeney et al. PHYSIOLOGICAL REVIEWS
- CD39 limits P2X7 receptor inflammatory signaling and attenuates sepsis-induced liver injury
- (2017) Luiz Eduardo Baggio Savio et al. JOURNAL OF HEPATOLOGY
- Alteration of sphingolipid metabolism as a putative mechanism underlying LPS-induced BBB disruption
- (2017) Rajkumar Vutukuri et al. JOURNAL OF NEUROCHEMISTRY
- Brain Barrier Breakdown as a Cause and Consequence of Neuroinflammation in Sepsis
- (2017) Lucineia Gainski Danielski et al. MOLECULAR NEUROBIOLOGY
- NADPH oxidase in brain injury and neurodegenerative disorders
- (2017) Merry W. Ma et al. Molecular Neurodegeneration
- The role of peripheral immune cells in the CNS in steady state and disease
- (2017) Marco Prinz et al. NATURE NEUROSCIENCE
- Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis
- (2017) Benjamin J. Andreone et al. NEURON
- Management of Septic Shock
- (2017) Rebecca E. Berger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway
- (2017) Aslihan Ugun-Klusek et al. Cell Death & Disease
- Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-κB signaling pathway after LPS treatment in neonatal rats
- (2017) Yingying Hu et al. Oncotarget
- Dexmedetomidine Attenuates Lipopolysaccharide Induced MCP-1 Expression in Primary Astrocyte
- (2017) Huan Liu et al. Biomed Research International
- Sepsis-Associated Encephalopathy: The Blood–Brain Barrier and the Sphingolipid Rheostat
- (2017) Stephen J. Kuperberg et al. Frontiers in Immunology
- Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations
- (2016) Carolin Fleischmann et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Hospital Incidence and Mortality Rates of Sepsis: An Analysis of Hospital Episode (DRG) Statistics in Germany From 2007 to 2013
- (2016) Carolin Fleischmann et al. Deutsches Arzteblatt International
- Septic encephalopathy and septic encephalitis
- (2016) Simone C. Tauber et al. Expert Review of Anti-Infective Therapy
- Oxygen consumption deficit in Huntington disease mouse brain under metabolic stress
- (2016) Song Lou et al. HUMAN MOLECULAR GENETICS
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
- (2016) Mervyn Singer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Interleukin-30 (IL27p28) alleviates experimental sepsis by modulating cytokine profile in NKT cells
- (2016) Jun Yan et al. JOURNAL OF HEPATOLOGY
- SPARC expression by cerebral microvascular endothelial cells in vitro and its influence on blood-brain barrier properties
- (2016) Samir Alkabie et al. Journal of Neuroinflammation
- HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer’s disease
- (2016) Barry W. Festoff et al. Journal of Neuroinflammation
- The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update
- (2016) Meng-Chen Lu et al. MEDICINAL RESEARCH REVIEWS
- Brain Oxidative Stress During Experimental Sepsis Is Attenuated by Simvastatin Administration
- (2016) Carlos Henrique Rocha Catalão et al. MOLECULAR NEUROBIOLOGY
- Pericytes of the neurovascular unit: key functions and signaling pathways
- (2016) Melanie D Sweeney et al. NATURE NEUROSCIENCE
- Nrf2–ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases
- (2016) Izaskun Buendia et al. PHARMACOLOGY & THERAPEUTICS
- Targeting Oxidative Stress in Central Nervous System Disorders
- (2016) Manisha Patel TRENDS IN PHARMACOLOGICAL SCIENCES
- Differential Paradigms in Animal Models of Sepsis
- (2016) S. Manoj Kumar Kingsley et al. Current Infectious Disease Reports
- Lactate as substrate for mitochondrial respiration in alveolar epithelial type II cells
- (2015) Robyn G. Lottes et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- The role of microglia activation in the development of sepsis-induced long-term cognitive impairment
- (2015) Monique Michels et al. BRAIN BEHAVIOR AND IMMUNITY
- Increasing the Permeability of the Blood-brain Barrier in Three Different Modelsin vivo
- (2015) Wei-Ye Liu et al. CNS Neuroscience & Therapeutics
- The dynamic blood-brain barrier
- (2015) James Keaney et al. FEBS Journal
- Brain barriers: Crosstalk between complex tight junctions and adherens junctions
- (2015) Silvia Tietz et al. JOURNAL OF CELL BIOLOGY
- Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit
- (2015) William A. Banks et al. Journal of Neuroinflammation
- Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling
- (2015) Lei Zhao et al. JOURNAL OF PINEAL RESEARCH
- Unknown
- (2015) Monique Michels et al. MOLECULAR MEDICINE
- GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration
- (2015) Ethan A Winkler et al. NATURE NEUROSCIENCE
- LPS Induces Occludin Dysregulation in Cerebral Microvascular Endothelial Cells via MAPK Signaling and Augmenting MMP-2 Levels
- (2015) Lan-hui Qin et al. Oxidative Medicine and Cellular Longevity
- Transmembrane proteins of the tight junctions at the blood–brain barrier: Structural and functional aspects
- (2015) Reiner F. Haseloff et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Mitochondrial Crisis in Cerebrovascular Endothelial Cells Opens the Blood–Brain Barrier
- (2015) Danielle N. Doll et al. STROKE
- The Blood–Brain Barrier
- (2015) Richard Daneman et al. Cold Spring Harbor Perspectives in Biology
- Mesenchymal stem cells stabilize the blood–brain barrier through regulation of astrocytes
- (2015) Hyun Jung Park et al. Stem Cell Research & Therapy
- Limb Ischemic Perconditioning Attenuates Blood-Brain Barrier Disruption by Inhibiting Activity of MMP-9 and Occludin Degradation after Focal Cerebral Ischemia
- (2015) Changhong Ren et al. Aging and Disease
- Cognitive decline after sepsis
- (2015) Djillali Annane et al. Lancet Respiratory Medicine
- Blood–brain barrier dysfunction in mice induced by lipopolysaccharide is attenuated by dapsone
- (2014) Ting Zhou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Polyclonal intravenous immunoglobulin: An important additional strategy in sepsis?
- (2014) R. Di Rosa et al. European Journal of Internal Medicine
- Activation of AMPK attenuates lipopolysaccharide-impaired integrity and function of blood–brain barrier in human brain microvascular endothelial cells
- (2014) Zhihong Zhao et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Targeting HMGB1 in the treatment of sepsis
- (2014) Haichao Wang et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- LPS and IL-1 differentially activate mouse and human astrocytes: Role of CD14
- (2014) Leonid Tarassishin et al. GLIA
- Angiogenesis revisited – role and therapeutic potential of targeting endothelial metabolism
- (2014) Peter Stapor et al. JOURNAL OF CELL SCIENCE
- Insulin alleviates the inflammatory response and oxidative stress injury in cerebral tissues in septic rats
- (2014) Qiyi Chen et al. Journal of Inflammation-London
- Omarigliptin (MK-3102): A Novel Long-Acting DPP-4 Inhibitor for Once-Weekly Treatment of Type 2 Diabetes
- (2014) Tesfaye Biftu et al. JOURNAL OF MEDICINAL CHEMISTRY
- The role of Nox2-derived ROS in the development of cognitive impairment after sepsis
- (2014) Marina S Hernandes et al. Journal of Neuroinflammation
- Evaluation of cathepsin B activity for degrading collagen IV using a surface plasmon resonance method and circular dichroism spectroscopy
- (2014) Atsushi Shoji et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Sepsis-associated encephalopathy versus sepsis-induced encephalopathy
- (2014) Samad EJ Golzari et al. LANCET NEUROLOGY
- Phosphoinositide 3-Kinase γ Affects LPS-Induced Disturbance of Blood–Brain Barrier Via Lipid Kinase-Independent Control of cAMP in Microglial Cells
- (2014) Adrian Frister et al. NEUROMOLECULAR MEDICINE
- The impact of microglial activation on blood-brain barrier in brain diseases
- (2014) Anna Carolina Carvalho da Fonseca et al. Frontiers in Cellular Neuroscience
- Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity
- (2014) Yao Yao et al. Nature Communications
- Mitochondria, endothelial cell function, and vascular diseases
- (2014) Xiaoqiang Tang et al. Frontiers in Physiology
- Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit
- (2014) Jean-Louis Vincent et al. Lancet Respiratory Medicine
- Traumatic Brain Injury: Oxidative Stress and Neuroprotection
- (2013) Carolin Cornelius et al. ANTIOXIDANTS & REDOX SIGNALING
- Fructose-1,6-bisphosphate ameliorates lipopolysaccharide-induced dysfunction of blood–brain barrier
- (2013) Sun Mi Seok et al. ARCHIVES OF PHARMACAL RESEARCH
- Metformin induces up-regulation of blood–brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells
- (2013) Fuyuko Takata et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nrf2 deficiency induces oxidative stress and promotes RANKL-induced osteoclast differentiation
- (2013) Seungha Hyeon et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ucf-101 protects against cerebral oxidative injury and cognitive impairment in septic rat
- (2013) YueYu Hu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Dietary fish oil reduces systemic inflammation and ameliorates sepsis-induced liver injury by up-regulating the peroxisome proliferator-activated receptor gamma-mediated pathway in septic mice
- (2013) Cheng-Chung Li et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Matrix Metalloproteinase-2 and Metalloproteinase-9 Activities are Associated with Blood–Brain Barrier Dysfunction in an Animal Model of Severe Sepsis
- (2013) Felipe Dal-Pizzol et al. MOLECULAR NEUROBIOLOGY
- Il1-β Involvement in Cognitive Impairment after Sepsis
- (2013) Francielle Mina et al. MOLECULAR NEUROBIOLOGY
- Development, maintenance and disruption of the blood-brain barrier
- (2013) Birgit Obermeier et al. NATURE MEDICINE
- Myeloperoxidase-Derived Oxidants Induce Blood-Brain Barrier Dysfunction In Vitro and In Vivo
- (2013) Andreas Üllen et al. PLoS One
- Understanding brain dysfunction in sepsis
- (2013) Romain Sonneville et al. Annals of Intensive Care
- Intravenous immunoglobulins prevent the breakdown of the blood-brain barrier in experimentally induced sepsis
- (2012) Figen Esen et al. CRITICAL CARE MEDICINE
- Getting to Know the Cast - Cellular Interactions and Signaling at the Neurovascular Unit
- (2012) Maarja Mae et al. CURRENT PHARMACEUTICAL DESIGN
- Matrix metalloproteinases and their impact on sinusal extension in chronic rhinosinusitis with nasal polyps
- (2012) Rafael Rossell Malinsky et al. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- Increased Oxidative Stress and Imbalance in Antioxidant Enzymes in the Brains of Alloxan-Induced Diabetic Rats
- (2012) Luciane B. Ceretta et al. Experimental Diabetes Research
- Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
- (2012) Azeb Tadesse Argaw et al. JOURNAL OF CLINICAL INVESTIGATION
- Population Burden of Long-Term Survivorship After Severe Sepsis in Older Americans
- (2012) Theodore J. Iwashyna et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Sepsis-associated encephalopathy
- (2012) Teneille E. Gofton et al. Nature Reviews Neurology
- Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells
- (2012) Junichi Matsumoto et al. NEUROSCIENCE LETTERS
- Exposure to Lipopolysaccharide and/or Unconjugated Bilirubin Impair the Integrity and Function of Brain Microvascular Endothelial Cells
- (2012) Filipa L. Cardoso et al. PLoS One
- Tight Junctions in Brain Barriers During Central Nervous System Inflammation
- (2011) Caroline Coisne et al. ANTIOXIDANTS & REDOX SIGNALING
- Traffic of leukocytes and cytokine up-regulation in the central nervous system in sepsis
- (2011) Clarissa M. Comim et al. INTENSIVE CARE MEDICINE
- Sildenafil attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-κB signaling pathways in N9 microglia
- (2011) Siqi Zhao et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- IL-9 Promotes Th17 Cell Migration into the Central Nervous System via CC Chemokine Ligand-20 Produced by Astrocytes
- (2011) Yan Zhou et al. JOURNAL OF IMMUNOLOGY
- Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide
- (2011) Andrej Kovac et al. Journal of Neuroinflammation
- RhoA and NF-κB are involved in lipopolysaccharide-induced brain microvascular cell line hyperpermeability
- (2011) F. He et al. NEUROSCIENCE
- Interleukin-1β causes long-term potentiation deficiency in a mouse model of septic encephalopathy
- (2011) Y. Imamura et al. NEUROSCIENCE
- Connecting Vascular and Nervous System Development: Angiogenesis and the Blood-Brain Barrier
- (2010) Stephen J. Tam et al. Annual Review of Neuroscience
- Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches
- (2010) Filipa Lourenço Cardoso et al. BRAIN RESEARCH REVIEWS
- The Role of Cerebral Vascular NFĸB in LPS-induced Inflammation: Differential Regulation of Efflux Transporter and Transporting Cytokine Receptors
- (2010) Weihong Pan et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis
- (2010) Theodore J. Iwashyna et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Tumor Necrosis Factor-α Mediates the Blood–Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells
- (2010) Tsuyoshi Nishioku et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Inhibition of endothelial cell migration through the down‑regulation of MMP-9 by A-kinase anchoring protein 12
- (2010) Woo Kim Molecular Medicine Reports
- Pericytes regulate the blood–brain barrier
- (2010) Annika Armulik et al. NATURE
- Angiotensin II induced cerebral microvascular inflammation and increased blood–brain barrier permeability via oxidative stress
- (2010) M. Zhang et al. NEUROSCIENCE
- DDS, 4,4'-diaminodiphenylsulfone, extends organismic lifespan
- (2010) S. C. Cho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipopolysaccharide-Activated Microglia Induce Dysfunction of the Blood–Brain Barrier in Rat Microvascular Endothelial Cells Co-Cultured with Microglia
- (2009) Noriko Sumi et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Matrix Metalloproteinases as Drug Targets in Infections Caused by Gram-Negative Bacteria and in Septic Shock
- (2009) I. Vanlaere et al. CLINICAL MICROBIOLOGY REVIEWS
- Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia
- (2009) D. Nayak et al. NEUROSCIENCE
- VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown
- (2009) Azeb Tadesse Argaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epoxyeicosanoid signaling in CNS function and disease
- (2009) Jeffrey J. Iliff et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Modulation of matrix remodeling by SPARC in neoplastic progression
- (2009) Alexandre Chlenski et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells
- (2008) Masaru Yamamoto et al. AMERICAN JOURNAL OF PATHOLOGY
- NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2
- (2008) Alyson A. Miller et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme
- (2008) L. Verstrepen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Detachment of Brain Pericytes from the Basal Lamina is Involved in Disruption of the Blood–Brain Barrier Caused by Lipopolysaccharide-Induced Sepsis in Mice
- (2008) Tsuyoshi Nishioku et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- SPARC is expressed by macroglia and microglia in the developing and mature nervous system
- (2008) Adele J. Vincent et al. DEVELOPMENTAL DYNAMICS
- Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by the p38 mitogen-activated protein kinase pathway
- (2008) Shinya Dohgu et al. EXPERIMENTAL NEUROLOGY
- Tight junctions and the modulation of barrier function in disease
- (2008) Carola Förster HISTOCHEMISTRY AND CELL BIOLOGY
- Lipopolysaccharide Impairs Blood–Brain Barrier P-glycoprotein Function in Mice Through Prostaglandin- and Nitric Oxide-Independent Pathways
- (2008) Mohamad A. Salkeni et al. Journal of Neuroimmune Pharmacology
- Ambivalent effect of immunoglobulins on the complement system: Activation versus inhibition
- (2008) Milan Basta MOLECULAR IMMUNOLOGY
- Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression
- (2008) Hui-Ming Gao et al. TRENDS IN IMMUNOLOGY
- The role of oxidative stress and NADPH oxidase in cerebrovascular disease
- (2008) Sophocles Chrissobolis et al. TRENDS IN MOLECULAR MEDICINE
- TNF is a key mediator of septic encephalopathy acting through its receptor, TNF receptor-1
- (2007) Jessy J. Alexander et al. NEUROCHEMISTRY INTERNATIONAL
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