Traumatic Brain Injury: Oxidative Stress and Neuroprotection

Evidence Linking Genetics, Environment, and Epigenetics to Impaired DNA Repair in Alzheimer's Disease

(2017) Fabio Coppedè et al.   JOURNAL OF ALZHEIMERS DISEASE

Hormesis

(2012) Soledad Matus et al.   Autophagy

Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury

(2012) Zonggang Hou et al.   BRAIN RESEARCH BULLETIN

A Review of Neuroprotection Pharmacology and Therapies in Patients with Acute Traumatic Brain Injury

(2012) Kevin W. McConeghy et al.   CNS DRUGS

Activation of Ras Signaling Pathway by 8-Oxoguanine DNA Glycosylase Bound to Its Excision Product, 8-Oxoguanine

(2012) Istvan Boldogh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hormetic effect of amyloid-beta peptide in synaptic plasticity and memory

(2012) Daniela Puzzo et al.   NEUROBIOLOGY OF AGING

Sirtuins as Regulators of the Yeast Metabolic Network

(2012) Markus Ralser et al.   Frontiers in Pharmacology

Mitochondrial longevity pathways

(2011) M.H. Vendelbo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

(2011) Ines Batinic-Haberle et al.   FREE RADICAL BIOLOGY AND MEDICINE

Age-related changes in brain mitochondrial DNA deletion and oxidative stress are differentially modulated by dietary fat type and coenzyme Q10

(2011) Julio J. Ochoa et al.   FREE RADICAL BIOLOGY AND MEDICINE

Age-dependent changes in 8-oxoguanine-DNA glycosylase activity are modulated by adaptive responses to physical exercise in human skeletal muscle

(2011) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during aging

(2011) Umakanta Swain et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Energy metabolism, proteotoxic stress and age-related dysfunction – Protection by carnosine

(2011) Alan R. Hipkiss   MOLECULAR ASPECTS OF MEDICINE

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

(2011) Nady Braidy et al.   PLoS One

The hormesis database: The occurrence of hormetic dose responses in the toxicological literature

(2011) Edward J. Calabrese et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Combined Exercise and Insulin-Like Growth Factor-1 Supplementation Induces Neurogenesis in Old Rats, but Do Not Attenuate Age-Associated DNA Damage

(2011) Erika Koltai et al.   REJUVENATION RESEARCH

Hormesis provides a generalized quantitative estimate of biological plasticity

(2011) Edward J. Calabrese et al.   Journal of Cell Communication and Signaling

Interaction of p53 with Tumor Suppressive and Oncogenic Signaling Pathways to Control Cellular Reactive Oxygen Species Production

(2010) María Fátima Ladelfa et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial DNA Damage and the Involvement of Antioxidant Defense and Repair System in Hippocampi of Rats with Chronic Seizures

(2010) Youting Lin et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments

(2010) James J Donkin et al.   CURRENT OPINION IN NEUROLOGY

Roles of dioxins and heavy metals in cancer and neurological diseases using ROS-mediated mechanisms

(2010) José M. Matés et al.   FREE RADICAL BIOLOGY AND MEDICINE

8-Oxo-7,8-dihydroguanine: Links to gene expression, aging, and defense against oxidative stress

(2010) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bomb blast, mild traumatic brain injury and psychiatric morbidity: A review

(2010) Jeffrey V. Rosenfeld et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

DNA Damage and Impairment of DNA Repair in Alzheimer's Disease

(2010) M. Obulesu et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease

(2010) Ricardo Gredilla et al.   NEUROBIOLOGY OF AGING

Modulation of PARP-1 and PARP-2 Expression by L-carnosine and Trehalose After LPS and INFγ-Induced Oxidative Stress

(2010) Vittoria Spina-Purrello et al.   NEUROCHEMICAL RESEARCH

Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

(2010) Jenna M. Ziebell et al.   Neurotherapeutics

Statins in traumatic brain injury

(2010) Elissa F. Wible et al.   Neurotherapeutics

Oxidation of DNA: Damage to Nucleobases

(2009) Sriram Kanvah et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nitric Oxide in Cell Survival: A Janus Molecule

(2009) Vittorio Calabrese et al.   ANTIOXIDANTS & REDOX SIGNALING

Pain and U-Shaped Dose Responses: Occurrence, Mechanisms, and Clinical Implications

(2009) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Simvastatin reduces secondary brain injury caused by cortical contusion in rats: Possible involvement of TLR4/NF-κB pathway

(2009) Gang Chen et al.   EXPERIMENTAL NEUROLOGY

The role of molecular chaperones in human misfolding diseases

(2009) Sarah A. Broadley et al.   FEBS LETTERS

Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases

(2009) Vittorio Calabrese   Frontiers in Bioscience-Landmark

The Shock of Aging: Molecular Chaperones and the Heat Shock Response in Longevity and Aging – A Mini-Review

(2009) Stuart K. Calderwood et al.   GERONTOLOGY

Inhibition of Poly(ADP-Ribose) Polymerase Suppresses Inflammation and Promotes Recovery after Ischemic Injury

(2009) Tiina M Kauppinen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Elevated metals compromise repair of oxidative DNA damage via the base excision repair pathway: implications of pathologic iron overload in the brain on integrity of neuronal DNA

(2009) Hui Li et al.   JOURNAL OF NEUROCHEMISTRY

Nicotinamide Prevents NAD+ Depletion and Protects Neurons Against Excitotoxicity and Cerebral Ischemia: NAD+ Consumption by SIRT1 may Endanger Energetically Compromised Neurons

(2009) Dong Liu et al.   NEUROMOLECULAR MEDICINE

SIRT1 deacetylates APE1 and regulates cellular base excision repair

(2009) Tohru Yamamori et al.   NUCLEIC ACIDS RESEARCH

Forty Percent Methionine Restriction Decreases Mitochondrial Oxygen Radical Production and Leak at Complex I During Forward Electron Flow and Lowers Oxidative Damage to Proteins and Mitochondrial DNA in Rat Kidney and Brain Mitochondria

(2009) Pilar Caro et al.   REJUVENATION RESEARCH

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

p53 Regulation of Metabolic Pathways

(2009) E. Gottlieb et al.   Cold Spring Harbor Perspectives in Biology

Neuroscience and Hormesis: Overview and General Findings

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Drug Therapies for Stroke and Traumatic Brain Injury Often Display U-Shaped Dose Responses: Occurrence, Mechanisms, and Clinical Implications

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Pharmacological Enhancement of Neuronal Survival

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Role of Free Radicals and Poly(ADP-Ribose)Polymerase-1 in the Development of Spinal Cord Injury: New Potential Therapeutic Targets

(2008) S. Cuzzocrea et al.   CURRENT MEDICINAL CHEMISTRY

Formamidopyrimidines in DNA: Mechanisms of formation, repair, and biological effects

(2008) Miral Dizdaroglu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The wanderings of a free radical

(2008) Barry Halliwell   FREE RADICAL BIOLOGY AND MEDICINE

Quantification of Poly(ADP-Ribose)-Modified Proteins in Cerebrospinal Fluid from Infants and Children after Traumatic Brain Injury

(2008) Ericka L Fink et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease

(2008) Carl Julien et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Activation of Heat Shock and Antioxidant Responses by the Natural Product Celastrol: Transcriptional Signatures of a Thiol-targeted Molecule

(2008) Amy Trott et al.   MOLECULAR BIOLOGY OF THE CELL

Cellular Stress Response: A Novel Target for Chemoprevention and Nutritional Neuroprotection in Aging, Neurodegenerative Disorders and Longevity

(2008) Vittorio Calabrese et al.   NEUROCHEMICAL RESEARCH

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE