Tight junctions in the blood–brain barrier promote edema formation and infarct size in stroke – Ambivalent effects of sealing proteins

Claudin-3-deficient C57BL/6J mice display intact brain barriers

(2019) Mariana Castro Dias et al.   Scientific Reports

Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice

(2019) Fabienne Benz et al.   eLife

Brain endothelial cell junctions after cerebral hemorrhage: Changes, mechanisms and therapeutic targets

(2018) Richard F Keep et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blood-brain barrier dysfunction and recovery after ischemic stroke

(2018) Xiaoyan Jiang et al.   PROGRESS IN NEUROBIOLOGY

Claudin-3 regulates bile canalicular paracellular barrier and cholesterol gallstone cores formation in mice

(2018) Hiroo Tanaka et al.   JOURNAL OF HEPATOLOGY

Angiopoietin-2-induced blood–brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling

(2016) Stefanie Gurnik et al.   ACTA NEUROPATHOLOGICA

Occludin controls HIV transcription in brain pericytes via regulation of SIRT-1 activation

(2016) Victor Castro et al.   FASEB JOURNAL

Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice

(2016) S. Donath et al.   JOURNAL OF NEUROSCIENCE

Redox Regulation of Cell Contacts by Tricellulin and Occludin: Redox-Sensitive Cysteine Sites in Tricellulin Regulate Both Tri- and Bicellular Junctions in Tissue Barriers as Shown in Hypoxia and Ischemia

(2015) Jimmi Cording et al.   ANTIOXIDANTS & REDOX SIGNALING

Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers

(2015) Christian Staat et al.   BIOMATERIALS

Vascular Signal Transducer and Activator of Transcription-3 Promotes Angiogenesis and Neuroplasticity Long-Term After Stroke

(2015) C. J. Hoffmann et al.   CIRCULATION

Dynamic regulation of aquaporin-4 water channels in neurological disorders

(2015) Ying Hsu et al.   CROATIAN MEDICAL JOURNAL

Pathogenesis of Brain Edema and Investigation into Anti-Edema Drugs

(2015) Shotaro Michinaga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroimmunomodulatory effects of transcranial laser therapy combined with intravenous tPA administration for acute cerebral ischemic injury

(2015) PhilipV Peplow   Neural Regeneration Research

Transmembrane proteins of the tight junctions at the blood–brain barrier: Structural and functional aspects

(2015) Reiner F. Haseloff et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Infarct Volume Prediction by Early Magnetic Resonance Imaging in a Murine Stroke Model Depends on Ischemia Duration and Time of Imaging

(2015) Christoph Leithner et al.   STROKE

“You Shall Not Pass”—tight junctions of the blood brain barrier

(2014) Hans-Christian Bauer et al.   Frontiers in Neuroscience

Disturbed function of the blood–cerebrospinal fluid barrier aggravates neuro-inflammation

(2013) Gijs Kooij et al.   ACTA NEUROPATHOLOGICA

Highly Conserved Cysteines Are Involved in the Oligomerization of Occludin—Redox Dependency of the Second Extracellular Loop

(2013) Christian Bellmann et al.   ANTIOXIDANTS & REDOX SIGNALING

Single-Cell Resolution Mapping of Neuronal Damage in Acute Focal Cerebral Ischemia Using Thallium Autometallography

(2013) Franziska Stöber et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Claudins and the Modulation of Tight Junction Permeability

(2013) Dorothee Günzel et al.   PHYSIOLOGICAL REVIEWS

Complexity and developmental changes in the expression pattern of claudins at the blood–CSF barrier

(2012) Ingrid Kratzer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization

(2012) J. Cording et al.   JOURNAL OF CELL SCIENCE

Assessing Post-Stroke Behavior in Mouse Models of Focal Ischemia

(2012) Mustafa Balkaya et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sodium Caprate Transiently Opens Claudin-5-Containing Barriers at Tight Junctions of Epithelial and Endothelial Cells

(2012) G. Del Vecchio et al.   MOLECULAR PHARMACEUTICS

Visualization and Quantitative Analysis of Reconstituted Tight Junctions Using Localization Microscopy

(2012) Rainer Kaufmann et al.   PLoS One

Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury

(2012) Matthew Campbell et al.   Nature Communications

Barrier Mechanisms in the Developing Brain

(2012) Norman R. Saunders et al.   Frontiers in Pharmacology

ZO Proteins and Redox-Dependent Processes

(2011) Lorenza González-Mariscal et al.   ANTIOXIDANTS & REDOX SIGNALING

Elucidating the principles of the molecular organization of heteropolymeric tight junction strands

(2011) Jörg Piontek et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hepatitis C Virus Infects the Endothelial Cells of the Blood-Brain Barrier

(2011) Nicola F. Fletcher et al.   GASTROENTEROLOGY

Specific Role of Tight Junction Proteins Claudin-5, Occludin, and ZO-1 of the Blood–Brain Barrier in a Focal Cerebral Ischemic Insult

(2011) Haixia Jiao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Neonatal Ichthyosis and Sclerosing Cholangitis Syndrome

(2011) Massimiliano Paganelli et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Amyloid-β Contributes to Blood–Brain Barrier Leakage in Transgenic Human Amyloid Precursor Protein Mice and in Humans With Cerebral Amyloid Angiopathy

(2011) Anika M.S. Hartz et al.   STROKE

Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes

(2010) Susanne Milatz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

(2010) Amanda M. Marchiando et al.   JOURNAL OF CELL BIOLOGY

Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress

(2009) Gwen McCaffrey. et al.   JOURNAL OF NEUROCHEMISTRY

Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone

(2008) Hongmin Xu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

Structure and function of claudins

(2007) Gerd Krause et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES