Oxygen consumption deficit in Huntington disease mouse brain under metabolic stress

Oxidative metabolism in YAC128 mouse model of Huntington's disease

(2015) James Hamilton et al.   HUMAN MOLECULAR GENETICS

Abnormalities in the Tricarboxylic Acid Cycle in Huntington Disease and in a Huntington Disease Mouse Model

(2015) Nima N. Naseri et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mutant Huntingtin and Elusive Defects in Oxidative Metabolism and Mitochondrial Calcium Handling

(2015) Nickolay Brustovetsky   MOLECULAR NEUROBIOLOGY

High-speed label-free functional photoacoustic microscopy of mouse brain in action

(2015) Junjie Yao et al.   NATURE METHODS

ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect

(2014) Eduardo N. Maldonado et al.   MITOCHONDRION

Inhibition of mitochondrial protein import by mutant huntingtin

(2014) Hiroko Yano et al.   NATURE NEUROSCIENCE

Early decrease of type 1 cannabinoid receptor binding and phosphodiesterase 10A activity in vivo in R6/2 Huntington mice

(2014) Maarten Ooms et al.   NEUROBIOLOGY OF AGING

Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington’s disease mice

(2014) Hollis McClory et al.   Acta Neuropathologica Communications

Non-Invasive Measurement of Cerebral Oxygen Metabolism in the Mouse Brain by Ultra-High Field 17O MR Spectroscopy

(2013) Weina Cui et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

An accurate method for the quantification of cytochrome C oxidase in tissue sections

(2013) Miguel Melendez-Ferro et al.   JOURNAL OF NEUROSCIENCE METHODS

Construction and Evaluation of Quantitative Small-Animal PET Probabilistic Atlases for [18F]FDG and [18F]FECT Functional Mapping of the Mouse Brain

(2013) Cindy Casteels et al.   PLoS One

Early Deficits in Glycolysis Are Specific to Striatal Neurons from a Rat Model of Huntington Disease

(2013) Caroline Gouarné et al.   PLoS One

Antioxidant and bioenergetic coupling between neurons and astrocytes

(2012) Seila Fernandez-Fernandez et al.   BIOCHEMICAL JOURNAL

OXPHOS mutations and neurodegeneration

(2012) Werner J H Koopman et al.   EMBO JOURNAL

Mitochondrial DNA damage Is associated with reduced mitochondrial bioenergetics in Huntington's disease

(2012) Almas Siddiqui et al.   FREE RADICAL BIOLOGY AND MEDICINE

Defective mitochondrial disulfide relay system, altered mitochondrial morphology and function in Huntington's disease

(2012) Eleonora Napoli et al.   HUMAN MOLECULAR GENETICS

Homeostatic Adaptations in Brain Energy Metabolism in Mouse Models of Huntington Disease

(2012) Ivan Tkac et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

R6/2 Huntington's Disease Mice Develop Early and Progressive Abnormal Brain Metabolism and Seizures

(2012) E. Cepeda-Prado et al.   JOURNAL OF NEUROSCIENCE

In vitro and in vivo studies of17O NMR sensitivity at 9.4 and 16.4 T

(2012) Ming Lu et al.   MAGNETIC RESONANCE IN MEDICINE

Abnormal response to cortical activation in early stages of Huntington disease

(2012) Fanny Mochel et al.   MOVEMENT DISORDERS

Simultaneous and noninvasive imaging of cerebral oxygen metabolic rate, blood flow and oxygen extraction fraction in stroke mice

(2012) Xiao-Hong Zhu et al.   NEUROIMAGE

Transcriptional integration of mitochondrial biogenesis

(2012) Richard C. Scarpulla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria

(2011) D De Stefani et al.   CELL DEATH AND DIFFERENTIATION

Bioenergetic dysfunction in Huntington's disease human cybrids

(2011) I. Luisa Ferreira et al.   EXPERIMENTAL NEUROLOGY

Early Alterations of Brain Cellular Energy Homeostasis in Huntington Disease Models

(2011) Fanny Mochel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cortical Metabolites as Biomarkers in the R6/2 Model of Huntington's Disease

(2011) Lori Zacharoff et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

(2011) Wenjun Song et al.   NATURE MEDICINE

Reduced creatine kinase as a central and peripheral biomarker in Huntington's disease

(2010) Jinho Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

(2010) J. Kim et al.   HUMAN MOLECULAR GENETICS

Platelet Mitochondrial Complex I and I+III Activities Do Not Correlate with Cerebral Mitochondrial Oxidative Metabolism

(2010) William J Powers et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mapping of cerebral oxidative metabolism with MRI

(2010) E. A. Mellon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

(2009) Liliana Menalled et al.   NEUROBIOLOGY OF DISEASE

N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking

(2008) A. L. Orr et al.   JOURNAL OF NEUROSCIENCE

A Large Number of Protein Expression Changes Occur Early in Life and Precede Phenotype Onset in a Mouse Model for Huntington Disease

(2008) Claus Zabel et al.   MOLECULAR & CELLULAR PROTEOMICS