Anti-Inflammatory Function of Fatty Acids and Involvement of Their Metabolites in the Resolution of Inflammation in Chronic Obstructive Pulmonary Disease

Elevated CO2 Levels Delay Skeletal Muscle Repair by Increasing Fatty Acid Oxidation

(2021) Ermelinda Ceco et al.   Frontiers in Physiology

Metabolic reprogramming in macrophage responses

(2021) Yang Liu et al.   Biomarker Research

Specialized Pro-Resolving Mediators and the Lymphatic System

(2021) Jamie D. Kraft et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A New E-Series Resolvin: RvE4 Stereochemistry and Function in Efferocytosis of Inflammation-Resolution

(2021) Stephania Libreros et al.   Frontiers in Immunology

“Cell Membrane Theory of Senescence” and the Role of Bioactive Lipids in Aging, and Aging Associated Diseases and Their Therapeutic Implications

(2021) Undurti N. Das   Biomolecules

Lung Immune Tone via Gut-Lung Axis: Gut-derived LPS and Short-chain Fatty Acids' immunometabolic regulation of Lung IL-1β, FFAR2 and FFAR3 Expression

(2021) Qing Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of Short Chain Fatty Acids and Apolipoproteins in the Regulation of Eosinophilia-Associated Diseases

(2021) Eva Maria Sturm et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

High-fiber diets attenuate emphysema development via modulation of gut microbiota and metabolism

(2021) Yoon Ok Jang et al.   Scientific Reports

Atherosclerosis as a risk factor in the prognosis of the survival of patients with COPD

(2021) S Kotlyarov et al.   European Heart Journal-Acute Cardiovascular Care

Molecular Mechanisms of Lipid Metabolism Disorders in Infectious Exacerbations of Chronic Obstructive Pulmonary Disease

(2021) Stanislav Kotlyarov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Supportive therapy during COVID-19: The proposed mechanism of short-chain fatty acids to prevent cytokine storm and multi-organ failure

(2021) M. Jardou et al.   MEDICAL HYPOTHESES

Effect of Omega-3 Fatty Acids on Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2021) Haichuan Yu et al.   International Journal of Chronic Obstructive Pulmonary Disease

Macrophages: The Good, the Bad, and the Gluttony

(2021) Ewan A. Ross et al.   Frontiers in Immunology

Bioinformatic Analysis of ABCA1 Gene Expression in Smoking and Chronic Obstructive Pulmonary Disease

(2021) Stanislav Kotlyarov et al.   Membranes

MCTR1 alleviates lipopolysaccharide‐induced acute lung injury by protecting lung endothelial glycocalyx

(2020) Hui Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Alternatively activated macrophages; a double-edged sword in allergic asthma

(2020) Mohamed Hamed Abdelaziz et al.   Journal of Translational Medicine

Lipid-based biomarkers for CVD, COPD, and aging – A translational perspective

(2020) Kim Ekroos et al.   PROGRESS IN LIPID RESEARCH

MCTR1 enhances the resolution of lipopolysaccharide‐induced lung injury through STAT6‐mediated resident M2 alveolar macrophage polarization in mice

(2020) Qian Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Circulating Short-Chain Fatty Acids Are Positively Associated with Adiposity Measures in Chinese Adults

(2020) Yiqing Wang et al.   Nutrients

Exploration of n-6 and n-3 Polyunsaturated Fatty Acids Metabolites Associated with Nutritional Levels in Patients with Severe Stable Chronic Obstructive Pulmonary Disease

(2020) Mingshan Xue et al.   International Journal of Chronic Obstructive Pulmonary Disease

The Long-Term Burden of COPD Exacerbations During Maintenance Therapy and Lung Function Decline

(2020) Marjan Kerkhof et al.   International Journal of Chronic Obstructive Pulmonary Disease

Omega-3 fatty acids improve flow-induced vasodilation by enhancing TRPV4 in arteries from diet-induced obese mice

(2020) Yifei Zhu et al.   CARDIOVASCULAR RESEARCH

Short-Chain Fatty Acids and Their Association with Signalling Pathways in Inflammation, Glucose and Lipid Metabolism

(2020) Jin He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of respiratory short-chain fatty acids on bronchial inflammation in asthma

(2020) Ho Joo Yoon et al.   World Allergy Organization Journal

TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema

(2020) Jonas Weber et al.   JCI Insight

Butyrate and Propionate Restore the Cytokine and House Dust Mite Compromised Barrier Function of Human Bronchial Airway Epithelial Cells

(2020) Levi B. Richards et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Protectin Family of Specialized Pro-resolving Mediators: Potent Immunoresolvents Enabling Innovative Approaches to Target Obesity and Diabetes

(2019) Trond Vidar Hansen et al.   Frontiers in Pharmacology

Saturated Fat Intake Is Associated with Lung Function in Individuals with Airflow Obstruction: Results from NHANES 2007–2012

(2019) Kasey Cornell et al.   Nutrients

Dynamics of Human Gut Microbiota and Short-Chain Fatty Acids in Response to Dietary Interventions with Three Fermentable Fibers

(2019) Nielson T. Baxter et al.   mBio

Histone Acetylation of Immune Regulatory Genes in Human Placenta in Association with Maternal Intake of Olive Oil and Fish Consumption

(2019) Nathalie Acevedo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of short-chain fatty acids in microbiota–gut–brain communication

(2019) Boushra Dalile et al.   Nature Reviews Gastroenterology & Hepatology

Omega-3 fatty acid intake and prevalent respiratory symptoms among U.S. adults with COPD

(2019) Chantal M. Lemoine S et al.   BMC Pulmonary Medicine

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

(2019) Annabell Bachem et al.   IMMUNITY

Proresolving Lipid Mediators: Endogenous Modulators of Oxidative Stress

(2019) Alessandro Leuti et al.   Oxidative Medicine and Cellular Longevity

Resolvin E3 attenuates allergic airway inflammation via the interleukin-23–interleukin-17A pathway

(2019) Makiko Sato et al.   FASEB JOURNAL

Cigarette Smoke Reduces Fatty Acid Catabolism, Leading to Apoptosis in Lung Endothelial Cells: Implication for Pathogenesis of COPD

(2019) Jiannan Gong et al.   Frontiers in Pharmacology

Maresin 1 alleviates dextran sulfate sodium-induced ulcerative colitis by regulating NRF2 and TLR4/NF-kB signaling pathway

(2019) Shujin Qiu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions

(2019) Nan Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Metabolic Reprogramming in Pulmonary Innate Immunity and Its Impact on Lung Diseases

(2019) Charalambos Michaeloudes et al.   Journal of Innate Immunity

COPD and the gut-lung axis: the therapeutic potential of fibre

(2019) Annalicia Vaughan et al.   Journal of Thoracic Disease

Resolution metabolomes activated by hypoxic environment

(2019) Paul C. Norris et al.   Science Advances

Dietary omega-6, but not omega-3, polyunsaturated or saturated fatty acids increase inflammation in primary lung mesenchymal cells

(2018) Sandra Rutting et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Macrophages and lipid metabolism

(2018) Anneleen Remmerie et al.   CELLULAR IMMUNOLOGY

Defining the “Frequent Exacerbator” Phenotype in COPD

(2018) Olivier Le Rouzic et al.   CHEST

Dietary Fiber Confers Protection against Flu by Shaping Ly6c − Patrolling Monocyte Hematopoiesis and CD8 + T Cell Metabolism

(2018) Aurélien Trompette et al.   IMMUNITY

AT-RVD1 repairs mouse lung after cigarette smoke-induced emphysema via downregulation of oxidative stress by NRF2/KEAP1 pathway

(2018) Sara Vergel Posso et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

(2018) Charles N. Serhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Maresins: Specialized Proresolving Lipid Mediators and Their Potential Role in Inflammatory-Related Diseases

(2018) Shi Tang et al.   MEDIATORS OF INFLAMMATION

Sodium Butyrate Inhibits Colorectal Cancer Cell Migration by Downregulating Bmi-1 Through Enhanced miR-200c Expression

(2018) Zhiyao Xu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Reactive Oxygen Species in Chronic Obstructive Pulmonary Disease

(2018) Samia Boukhenouna et al.   Oxidative Medicine and Cellular Longevity

Macrophage polarization and allergic asthma

(2018) Arjun Saradna et al.   Translational Research

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

(2018) Oliver Werz et al.   Nature Communications

Obesity, Inflammation, Toll-Like Receptor 4 and Fatty Acids

(2018) Marcelo Rogero et al.   Nutrients

Metabolic Modulation in Macrophage Effector Function

(2018) Ciana Diskin et al.   Frontiers in Immunology

Long-term consumption of fruits and vegetables and risk of chronic obstructive pulmonary disease: a prospective cohort study of women

(2018) Joanna Kaluza et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Resolution of chronic inflammatory disease: universal and tissue-specific concepts

(2018) Georg Schett et al.   Nature Communications

Short-chain fatty acids increase TNFα-induced inflammation in primary human lung mesenchymal cells through the activation of p38 MAPK

(2018) Sandra Rutting et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Relationship between Serum Omega-3 Fatty Acid and Asthma Endpoints

(2018) Shahieda Adams et al.   International Journal of Environmental Research and Public Health

Lipoxin and Resolvin Receptors Transducing the Resolution of Inflammation in Cardiovascular Disease

(2018) John Pirault et al.   Frontiers in Pharmacology

Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls

(2018) Anne M. van der Does et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Dietary Fiber Intake and Risk of Chronic Obstructive Pulmonary Disease

(2017) Joanna Kaluza et al.   EPIDEMIOLOGY

Chronic Obstructive Pulmonary Disease Phenotypes: Implications for Care

(2017) Shireen Mirza et al.   MAYO CLINIC PROCEEDINGS

Bronchoprotective mechanisms for specialized pro-resolving mediators in the resolution of lung inflammation

(2017) Melody G. Duvall et al.   MOLECULAR ASPECTS OF MEDICINE

The role of pro-resolving lipid mediators in ocular diseases

(2017) Jessica Wei et al.   MOLECULAR ASPECTS OF MEDICINE

Resolvin D1 enhances the resolution of lung inflammation caused by long-term Pseudomonas aeruginosa infection

(2017) M Codagnone et al.   Mucosal Immunology

Arachidonic acid and lipoxinA4 attenuate streptozotocin-induced cytotoxicity to RIN5 F cells in vitro and type 1 and type 2 diabetes mellitus in vivo

(2017) Naveen K.V. Gundala et al.   NUTRITION

Maresin 1 Ameliorates Lung Ischemia/Reperfusion Injury by Suppressing Oxidative Stress via Activation of the Nrf-2-Mediated HO-1 Signaling Pathway

(2017) Quanchao Sun et al.   Oxidative Medicine and Cellular Longevity

Fruit and vegetable consumption and risk of COPD: a prospective cohort study of men

(2017) Joanna Kaluza et al.   THORAX

Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

Omega-3 Fatty Acids Modulate TRPV4 Function through Plasma Membrane Remodeling

(2017) Rebeca Caires et al.   Cell Reports

The Human Microbiota in Health and Disease

(2017) Baohong Wang et al.   Engineering

Saturated fatty acids trigger TLR4-mediated inflammatory response

(2016) D.M. Rocha et al.   ATHEROSCLEROSIS

Macrophage fatty acid oxidation and its roles in macrophage polarization and fatty acid-induced inflammation

(2016) Dmitry Namgaladze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Arachidonic acid and lipoxin A4 attenuate alloxan-induced cytotoxicity to RIN5F cells in vitro and type 1 diabetes mellitus in vivo

(2016) Naveen K.V. Gundala et al.   BIOFACTORS

Formation of propionate and butyrate by the human colonic microbiota

(2016) Petra Louis et al.   ENVIRONMENTAL MICROBIOLOGY

Resolvin D1 Polarizes Primary Human Macrophages toward a Proresolution Phenotype through GPR32

(2016) Mattia Schmid et al.   JOURNAL OF IMMUNOLOGY

ResolvinD1 reduces apoptosis and inflammation in primary human alveolar epithelial type 2 cells

(2016) Wanli Xie et al.   LABORATORY INVESTIGATION

Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis

(2016) Ruidong Li et al.   MEDIATORS OF INFLAMMATION

Fatty acid synthesis configures the plasma membrane for inflammation in diabetes

(2016) Xiaochao Wei et al.   NATURE

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

Weight gain in anorexia nervosa does not ameliorate the faecal microbiota, branched chain fatty acid profiles and gastrointestinal complaints

(2016) Isabelle Mack et al.   Scientific Reports

The administration of a high refined carbohydrate diet promoted an increase in pulmonary inflammation and oxidative stress in mice exposed to cigarette smoke

(2016) Karina Pena et al.   International Journal of Chronic Obstructive Pulmonary Disease

Intestinal Microbiota and Microbial Metabolites Are Changed in a Pig Model Fed a High-Fat/Low-Fiber or a Low-Fat/High-Fiber Diet

(2016) Sonja N. Heinritz et al.   PLoS One

Resolvin D1 Reduces Emphysema and Chronic Inflammation

(2015) Hsi-Min Hsiao et al.   AMERICAN JOURNAL OF PATHOLOGY

Resolvins Attenuate Inflammation and Promote Resolution in Cigarette Smoke-Exposed Human Macrophages

(2015) Amanda Croasdell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

(2015) Charles N. Serhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Short-chain fatty acids affect cystic fibrosis airway inflammation and bacterial growth

(2015) Peyman Ghorbani et al.   EUROPEAN RESPIRATORY JOURNAL

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

ChemR23, the Receptor for Chemerin and Resolvin E1, Is Expressed and Functional on M1 but Not on M2 Macrophages

(2015) Magdalena Herová et al.   JOURNAL OF IMMUNOLOGY

Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation

(2015) R E Abdulnour et al.   Mucosal Immunology

Paucity of evidence for a relationship between long-chain omega-3 fatty acid intake and chronic obstructive pulmonary disease: a systematic review

(2015) Ashley S. Fulton et al.   NUTRITION REVIEWS

The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution

(2015) Charles N. Serhan et al.   SEMINARS IN IMMUNOLOGY

First total synthesis of the macrophage derived anti-inflammatory and pro-resolving lipid mediator Maresin 2

(2015) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

First total synthesis of pro-resolving and tissue-regenerative Maresin sulfido-conjugates

(2015) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Physiological Impact of Abnormal Lipoxin A4Production on Cystic Fibrosis Airway Epithelium and Therapeutic Potential

(2015) Gerard Higgins et al.   Biomed Research International

Inverse Relationship between Serum Lipoxin A4 Level and the Risk of Metabolic Syndrome in a Middle-Aged Chinese Population

(2015) Dan Yu et al.   PLoS One

Cigarette Smoke–Induced Disruption of Bronchial Epithelial Tight Junctions Is Prevented by Transforming Growth Factor-β

(2014) Andrea C. Schamberger et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Short-term cigarette smoke exposure leads to metabolic alterations in lung alveolar cells

(2014) Amit R. Agarwal et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Activation of P2RY11 and ATP Release by LXA4Restores the Airway Surface Liquid Layer and Epithelial Repair in Cystic Fibrosis

(2014) Gerard Higgins et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The effect of natural and synthetic fatty acids on membrane structure, microdomain organization, cellular functions and human health

(2014) Maitane Ibarguren et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Resolution of acute inflammation bridges the gap between innate and adaptive immunity

(2014) J. Newson et al.   BLOOD

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

The Arachidonic Acid Metabolome Serves as a Conserved Regulator of Cholesterol Metabolism

(2014) Egon Demetz et al.   Cell Metabolism

Resolution of inflammation: targeting GPCRs that interact with lipids and peptides

(2014) Jenna L. Cash et al.   DRUG DISCOVERY TODAY

Rapid Appearance of Resolvin Precursors in Inflammatory Exudates: Novel Mechanisms in Resolution

(2014) K. Kasuga et al.   JOURNAL OF IMMUNOLOGY

Synthesis and Anti-inflammatory and Pro-resolving Activities of 22-OH-PD1, a Monohydroxylated Metabolite of Protectin D1

(2014) Jørn E. Tungen et al.   JOURNAL OF NATURAL PRODUCTS

Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR–S6K pathway

(2014) J Park et al.   Mucosal Immunology

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

(2014) Bart Everts et al.   NATURE IMMUNOLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Inflammation and Cancer: Role of Annexin A1 and FPR2/ALX in Proliferation and Metastasis in Human Laryngeal Squamous Cell Carcinoma

(2014) Thaís Santana Gastardelo et al.   PLoS One

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial microbiome of lungs in COPD

(2014) Don Sin et al.   International Journal of Chronic Obstructive Pulmonary Disease

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents

(2013) Jesmond Dalli et al.   CHEMISTRY & BIOLOGY

Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23

(2013) Jenna L Cash et al.   EMBO REPORTS

Plasticity of Leukocytic Exudates in Resolving Acute Inflammation Is Regulated by MicroRNA and Proresolving Mediators

(2013) Yongsheng Li et al.   IMMUNITY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Impact of Dietary Fiber Fermentation from Cereal Grains on Metabolite Production by the Fecal Microbiota from Normal Weight and Obese Individuals

(2013) Junyi Yang et al.   JOURNAL OF MEDICINAL FOOD

Modification of the fatty acid composition of the erythrocyte membrane in patients with chronic respiratory diseases

(2013) Tatyana P Novgorodtseva et al.   Lipids in Health and Disease

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Smoking and fluidity of erythrocyte membranes: A high resolution scanning electron and atomic force microscopy investigation

(2013) Etheresia Pretorius et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Smoking Cessation Induces Profound Changes in the Composition of the Intestinal Microbiota in Humans

(2013) Luc Biedermann et al.   PLoS One

A Novel Anti-Inflammatory and Pro-Resolving Role for Resolvin D1 in Acute Cigarette Smoke-Induced Lung Inflammation

(2013) Hsi-Min Hsiao et al.   PLoS One

Arachidonic acid and lipoxin A4 as possible endogenous anti-diabetic molecules

(2013) Undurti N. Das   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Lipoxin A4 Regulates Natural Killer Cell and Type 2 Innate Lymphoid Cell Activation in Asthma

(2013) C. Barnig et al.   Science Translational Medicine

Resolvin D1 Receptor Stereoselectivity and Regulation of Inflammation and Proresolving MicroRNAs

(2012) Sriram Krishnamoorthy et al.   AMERICAN JOURNAL OF PATHOLOGY

The Lung Tissue Microbiome in Chronic Obstructive Pulmonary Disease

(2012) Marc A. Sze et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci

(2012) Lucy V. Norling et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators

(2012) J. Dalli et al.   BLOOD

HDAC Inhibitors Augmented Cell Migration and Metastasis through Induction of PKCs Leading to Identification of Low Toxicity Modalities for Combination Cancer Therapy

(2012) K.-T. Lin et al.   CLINICAL CANCER RESEARCH

Lipids of Erythrocyte Membranes of COPD Patients: A Quantitative and Qualitative Study

(2012) Sukanya Gangopadhyay et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

(2012) Charles N. Serhan et al.   FASEB JOURNAL

Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid

(2012) Yosuke Isobe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resolvin E2 Formation and Impact in Inflammation Resolution

(2012) S. F. Oh et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 and Aspirin-Triggered Resolvin D1 Promote Resolution of Allergic Airways Responses

(2012) A. P. Rogerio et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of triglyceride accumulation in activated macrophages

(2012) Kenneth R. Feingold et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation

(2012) D. El Kebir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Total synthesis of the macrophage derived anti-inflammatory lipid mediator Maresin 1

(2012) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Short chain fatty acids and their receptors: new metabolic targets

(2012) Brian T. Layden et al.   Translational Research

Profile of eicosanoids in breath condensate in asthma and COPD

(2012) Leandro Genehr Fritscher et al.   Journal of Breath Research

Serial Analysis of the Gut and Respiratory Microbiome in Cystic Fibrosis in Infancy: Interaction between Intestinal and Respiratory Tracts and Impact of Nutritional Exposures

(2012) J. C. Madan et al.   mBio

Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

(2012) Trond Ulven   Frontiers in Endocrinology

Alternative Macrophage Activation and Metabolism

(2011) Justin I. Odegaard et al.   Annual Review of Pathology-Mechanisms of Disease

Lipid synthesis in macrophages during inflammation in vivo: Effect of agonists of peroxisome proliferator activated receptors α and γ and of retinoid X receptors

(2011) E. N. Posokhova et al.   BIOCHEMISTRY-MOSCOW

Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease

(2011) Jesper Z. Haeggström et al.   CHEMICAL REVIEWS

Novel Proresolving Aspirin-Triggered DHA Pathway

(2011) Charles N. Serhan et al.   CHEMISTRY & BIOLOGY

The relationship between gut microbiota and weight gain in humans

(2011) Emmanouil Angelakis et al.   Future Microbiology

Smoking-Induced Alterations in Platelet Membrane Fluidity and Na+/K+-ATPase Activity in Chronic Cigarette Smokers

(2011) Pannuru Padmavathi et al.   Journal of Atherosclerosis and Thrombosis

Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation

(2011) Sungwhan F. Oh et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolvin D1 protects mice from LPS-induced acute lung injury

(2011) Bin Wang et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Aspirin-Triggered Lipoxin and Resolvin E1 Modulate Vascular Smooth Muscle Phenotype and Correlate with Peripheral Atherosclerosis

(2010) Karen J. Ho et al.   AMERICAN JOURNAL OF PATHOLOGY

The relationship of dietary patterns with adult lung function and COPD

(2010) S. O. Shaheen et al.   EUROPEAN RESPIRATORY JOURNAL

Ceramide-rich platforms in transmembrane signaling

(2010) Branka Stancevic et al.   FEBS LETTERS

Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models

(2010) E F Murphy et al.   GUT

Butyrate in vitro immune-modulatory effects might be mediated through a proliferation-related induction of apoptosis

(2010) Elvira Bailón et al.   IMMUNOBIOLOGY

Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils

(2010) Hannu Kankaanranta et al.   Journal of Inflammation-London

Dietary intake of isoflavones and polyunsaturated fatty acids associated with lung function, breathlessness and the prevalence of chronic obstructive pulmonary disease: Possible protective effect of traditional Japanese diet

(2010) Fumi Hirayama et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

(2010) S. Krishnamoorthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteolytic regulatory mechanism of chemerin bioactivity

(2009) X.-Y. Du et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

15-Epi-lipoxin A4Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury

(2009) Driss El Kebir et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

(2009) M. Thangaraju et al.   CANCER RESEARCH

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

(2009) Marie A. Hildebrandt et al.   GASTROENTEROLOGY

Resolvin E1 Receptor Activation Signals Phosphorylation and Phagocytosis

(2009) Taisuke Ohira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Anti-Inflammatory and Proresolving Mediator Resolvin E1 Protects Mice from Bacterial Pneumonia and Acute Lung Injury

(2009) H. Seki et al.   JOURNAL OF IMMUNOLOGY

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis

(2009) Matthew Spite et al.   NATURE

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways

(2009) Michiko Aoyama et al.   NUTRITION

Microbiota and SCFA in Lean and Overweight Healthy Subjects

(2009) Andreas Schwiertz et al.   Obesity

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family

(2009) R. D. Ye et al.   PHARMACOLOGICAL REVIEWS

Short-chain fatty acids act as antiinflammatory mediatorsby regulating prostaglandin E2 and cytokines

(2009) Mary Ann Cox et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators

(2008) Aksam J. Merched et al.   FASEB JOURNAL

Synthetic chemerin-derived peptides suppress inflammation through ChemR23

(2008) Jenna L. Cash et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis

(2008) Masako Kohyama et al.   NATURE

Tonic inhibition of chemotaxis in human plasma

(2008) S. E. Malawista et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune mechanisms linking non-esterified fatty acids and respiratory disease

(2008) L WOOD et al.   PROGRESS IN LIPID RESEARCH

The relation between dietary intake of individual fatty acids, FEV1 and respiratory disease in Dutch adults

(2007) T M McKeever et al.   THORAX