Molecular Mechanisms of Lipid Metabolism Disorders in Infectious Exacerbations of Chronic Obstructive Pulmonary Disease

Finding Order in the Chaos: Outstanding questions in Klebsiella pneumoniae pathogenesis

(2021) Shekina Gonzalez-Ferrer et al.   INFECTION AND IMMUNITY

The role of oxidised self-lipids and alveolar macrophage CD1b expression in COPD

(2021) Miranda P. Ween et al.   Scientific Reports

Statins in High-Risk Chronic Obstructive Pulmonary Disease Outpatients: No Impact on Time to First Exacerbation and All-Cause Mortality – The STATUETTE Cohort Study

(2021) Mathias Damkjær et al.   International Journal of Chronic Obstructive Pulmonary Disease

Economic Burden of COPD by Disease Severity – A Nationwide Cohort Study in Denmark

(2021) Anders Løkke et al.   International Journal of Chronic Obstructive Pulmonary Disease

Association Between Statin Use and Exacerbation of Chronic Obstructive Pulmonary Disease Among Patients Receiving Corticosteroids

(2021) Yi-Jen Huang et al.   International Journal of Chronic Obstructive Pulmonary Disease

Editorial: Role of Lipid Rafts in Anti-microbial Immune Response

(2021) Maria Cristina Gagliardi et al.   Frontiers in Immunology

Specialized Pro-Resolving Mediators as Potential Regulators of Inflammatory Macrophage Responses in COVID-19

(2021) Maria G. Balta et al.   Frontiers in Immunology

Role of Apoptotic Cell Clearance in Pneumonia and Inflammatory Lung Disease

(2021) David Jiao Zheng et al.   Pathogens

Metabolomic Profiling Reveals Sex Specific Associations with Chronic Obstructive Pulmonary Disease and Emphysema

(2021) Lucas A. Gillenwater et al.   Metabolites

Participation of ABCA1 Transporter in Pathogenesis of Chronic Obstructive Pulmonary Disease

(2021) Stanislav Kotlyarov   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bacterial Membrane Vesicles in Pneumonia: From Mediators of Virulence to Innovative Vaccine Candidates

(2021) Felix Behrens et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

(2021) Irene Jurado-Martín et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The ABCA1-efferocytosis axis: A new strategy to protect against atherosclerosis

(2021) Wujun Chen et al.   CLINICA CHIMICA ACTA

The Role of ABC Transporters in Lipid Metabolism and the Comorbid Course of Chronic Obstructive Pulmonary Disease and Atherosclerosis

(2021) Stanislav Kotlyarov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pro-Resolving Ligands Orchestrate Phagocytosis

(2021) Christa Decker et al.   Frontiers in Immunology

Deciphering the role of the capsule of Klebsiella pneumoniae during pathogenesis: A cautionary tale

(2020) Olaya Rendueles   MOLECULAR MICROBIOLOGY

Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD)

(2020) Christina W. Agudelo et al.   PLoS One

Statin Use and the Risk of Subsequent Hospitalized Exacerbations in COPD Patients with Frequent Exacerbations

(2020) Chieh-Mo Lin et al.   International Journal of Chronic Obstructive Pulmonary Disease

New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages

(2020) Ana Batista-Gonzalez et al.   Frontiers in Immunology

Mechanisms of Epithelial Immunity Evasion by Respiratory Bacterial Pathogens

(2020) Lokesh Sharma et al.   Frontiers in Immunology

Cigarette smoke increases susceptibility to infection in lung epithelial cells by upregulating caveolin-dependent endocytosis

(2020) Parker F. Duffney et al.   PLoS One

Inhaled Corticosteroids in COPD: Trying to Make a Long Story Short

(2020) Claudio Tantucci et al.   International Journal of Chronic Obstructive Pulmonary Disease

Do ABC transporters regulate plasma membrane organization?

(2020) Ambroise Wu et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Differential effects of the Akt pathway on the internalization of Klebsiella by lung epithelium and macrophages

(2020) De Chang et al.   Innate Immunity

Alveolar lipids in pulmonary disease. A review

(2020) Christina W. Agudelo et al.   Lipids in Health and Disease

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2020) Joan B Soriano et al.   Lancet Respiratory Medicine

Host Lipid Rafts as the Gates for Listeria monocytogenes Infection: A Mini-Review

(2020) Yu-Huan Tsai et al.   Frontiers in Immunology

The Beauty of Asymmetric Membranes: Reconstitution of the Outer Membrane of Gram-Negative Bacteria

(2020) Laura Paulowski et al.   Frontiers in Cell and Developmental Biology

Specialized pro-resolving mediator network: an update on production and actions

(2020) Nan Chiang et al.   Essays in Biochemistry

Structural modifications of lipid membranes exposed to statins – Langmuir monolayer and PM-IRRAS study

(2020) Michalina Zaborowska et al.   JOURNAL OF MOLECULAR LIQUIDS

Specialized proresolving mediators in infection and lung injury

(2020) Shayna Sandhaus et al.   BIOFACTORS

Lipid larceny: channelizing host lipids for establishing successful pathogenesis by bacteria

(2020) Ritika Chatterjee et al.   Virulence

Risk of Pneumonia Associated with Inhaled Corticosteroid in Patients with Chronic Obstructive Pulmonary Disease: A Korean Population-Based Study

(2020) Ji-Ho Lee et al.   International Journal of Chronic Obstructive Pulmonary Disease

Quenching the fires: Pro-resolving mediators, air pollution, and smoking

(2019) Thomas H. Thatcher et al.   PHARMACOLOGY & THERAPEUTICS

HDL and Reverse Cholesterol Transport

(2019) Mireille Ouimet et al.   CIRCULATION RESEARCH

Geographic distribution of COPD prevalence in the World displayed by Geographic Information System maps

(2019) Ignacio Blanco et al.   EUROPEAN RESPIRATORY JOURNAL

The Interaction of Klebsiella pneumoniae With Lipid Rafts-Associated Cholesterol Increases Macrophage-Mediated Phagocytosis Due to Down Regulation of the Capsule Polysaccharide

(2019) Miguel A. Ares et al.   Frontiers in Cellular and Infection Microbiology

The Metabolic Signature of Macrophage Responses

(2019) Antonella Viola et al.   Frontiers in Immunology

Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma

(2019) Eitan Halper-Stromberg et al.   Metabolites

Prognosis of COPD depends on severity of exacerbation history: A population-based analysis

(2019) Yunus Çolak et al.   RESPIRATORY MEDICINE

Cigarette Smoke Reduces Fatty Acid Catabolism, Leading to Apoptosis in Lung Endothelial Cells: Implication for Pathogenesis of COPD

(2019) Jiannan Gong et al.   Frontiers in Pharmacology

Diverse Facets of Sphingolipid Involvement in Bacterial Infections

(2019) Tobias C. Kunz et al.   Frontiers in Cell and Developmental Biology

Sphingomyelin Breakdown in T Cells: Role of Membrane Compartmentalization in T Cell Signaling and Interference by a Pathogen

(2019) Elita Avota et al.   Frontiers in Cell and Developmental Biology

A Comprehensive Review on the Manipulation of the Sphingolipid Pathway by Pathogenic Bacteria

(2019) Monica Rolando et al.   Frontiers in Cell and Developmental Biology

Prevalence, Characteristics, and Prognosis of Early COPD: The Copenhagen General Population Study

(2019) Yunus Çolak et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of Omega-3 Fatty Acids on Immune Cells

(2019) Saray Gutiérrez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation

(2019) Hang Fu et al.   Cell Death & Disease

Structural Lesions of Proteins Connected to Lipid Membrane Damages Caused by Radical Stress: Assessment by Biomimetic Systems and Raman Spectroscopy

(2019) Torreggiani et al.   Biomolecules

Risk factors of chronic obstructive pulmonary disease exacerbations

(2019) Stanca‐Patricia Hogea et al.   Clinical Respiratory Journal

The ins and outs of lipid rafts: Functions in intracellular cholesterol homeostasis, microparticles, and cell membranes

(2019) Amber B Ouweneel et al.   JOURNAL OF LIPID RESEARCH

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Macrophages and lipid metabolism

(2018) Anneleen Remmerie et al.   CELLULAR IMMUNOLOGY

In vitro antibacterial effects of statins against bacterial pathogens causing skin infections

(2018) Humphrey H. T. Ko et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

A critical role for ABC transporters in persistent lung inflammation in the development of emphysema after smoke exposure

(2018) Jarrod Sonett et al.   FASEB JOURNAL

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

(2018) Charles N. Serhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Pneumonic and non-pneumonic exacerbations in bronchiectasis: Clinical and microbiological differences

(2018) Eva Polverino et al.   JOURNAL OF INFECTION

Specialized Proresolving Mediators in Innate and Adaptive Immune Responses in Airway Diseases

(2018) Nandini Krishnamoorthy et al.   PHYSIOLOGICAL REVIEWS

Exacerbation induces a microbiota shift in sputa of COPD patients

(2018) Eric Jubinville et al.   PLoS One

Clinical Pharmacology of Corticosteroids

(2018) Dennis M Williams   Respiratory Care

Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations

(2018) David Mayhew et al.   THORAX

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

(2018) Oliver Werz et al.   Nature Communications

Obesity, Inflammation, Toll-Like Receptor 4 and Fatty Acids

(2018) Marcelo Rogero et al.   Nutrients

Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways

(2018) Ariadna Fernández-Calvet et al.   Scientific Reports

Influence of cholesterol/caveolin-1/caveolae homeostasis on membrane properties and substrate adhesion characteristics of adult human mesenchymal stem cells

(2018) Jihee Sohn et al.   Stem Cell Research & Therapy

Exogenous fatty acids alter phospholipid composition, membrane permeability, capacity for biofilm formation, and antimicrobial peptide susceptibility in Klebsiella pneumoniae

(2018) Chelsea R. Hobby et al.   MicrobiologyOpen

The Role of Lipid Metabolism in T Lymphocyte Differentiation and Survival

(2018) Duncan Howie et al.   Frontiers in Immunology

The lung tissue microbiota of mild and moderate chronic obstructive pulmonary disease

(2018) Alexa A. Pragman et al.   Microbiome

Arachidonic acid and other unsaturated fatty acids and some of their metabolites function as endogenous antimicrobial molecules: A review

(2018) Undurti N. Das   Journal of Advanced Research

Pseudomonas aeruginosa responds to exogenous polyunsaturated fatty acids (PUFAs) by modifying phospholipid composition, membrane permeability, and phenotypes associated with virulence

(2018) Lyssa Y. Baker et al.   BMC MICROBIOLOGY

Sphingolipids and lipid rafts: Novel concepts and methods of analysis

(2018) Erhard Bieberich   CHEMISTRY AND PHYSICS OF LIPIDS

Docosahexaenoic acid antagonizes the boosting effect of palmitic acid on LPS inflammatory signaling by inhibiting gene transcription and ceramide synthesis

(2018) Junfei Jin et al.   PLoS One

Bacterial load and defective monocyte-derived macrophage bacterial phagocytosis in biomass-smoke COPD

(2018) Baishakhi Ghosh et al.   EUROPEAN RESPIRATORY JOURNAL

The Complex Interplay between Lipids, Immune System and Interleukins in Cardio-Metabolic Diseases

(2018) Stella Bernardi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Klebsiella pneumoniae infection of murine neutrophils impairs their efferocytic clearance by modulating cell death machinery

(2018) Christopher N. Jondle et al.   PLoS Pathogens

The Interplay Between Immune Response and Bacterial Infection in COPD: Focus Upon Non-typeable Haemophilus influenzae

(2018) Yu-Ching Su et al.   Frontiers in Immunology

Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls

(2018) Anne M. van der Does et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Interaction of statins with phospholipid bilayers studied by solid-state NMR spectroscopy

(2018) Leisan F. Galiullina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mechanistic insight into the function of the microbiome in lung diseases

(2017) Niki D.J. Ubags et al.   EUROPEAN RESPIRATORY JOURNAL

Lipid composition of membrane microdomains isolated detergent-free from PUFA supplemented RAW264.7 macrophages

(2017) Christine Hellwing et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Participation of Necroptosis in the Host Response to Acute Bacterial Pneumonia

(2017) Danielle Ahn et al.   Journal of Innate Immunity

Chronic Obstructive Pulmonary Disease Phenotypes: Implications for Care

(2017) Shireen Mirza et al.   MAYO CLINIC PROCEEDINGS

Bronchoprotective mechanisms for specialized pro-resolving mediators in the resolution of lung inflammation

(2017) Melody G. Duvall et al.   MOLECULAR ASPECTS OF MEDICINE

Resolvin D1 enhances the resolution of lung inflammation caused by long-term Pseudomonas aeruginosa infection

(2017) M Codagnone et al.   Mucosal Immunology

New opportunities for managing acute and chronic lung infections

(2017) William O. C. M. Cookson et al.   NATURE REVIEWS MICROBIOLOGY

The microbiota of the respiratory tract: gatekeeper to respiratory health

(2017) Wing Ho Man et al.   NATURE REVIEWS MICROBIOLOGY

The mystery of membrane organization: composition, regulation and roles of lipid rafts

(2017) Erdinc Sezgin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A prospective, observational cohort study of the seasonal dynamics of airway pathogens in the aetiology of exacerbations in COPD

(2017) Tom M A Wilkinson et al.   THORAX

Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

Bacterial Topography of the Healthy Human Lower Respiratory Tract

(2017) Robert P. Dickson et al.   mBio

The microbiota protects against respiratory infection via GM-CSF signaling

(2017) Rebecca L. Brown et al.   Nature Communications

Characterization of throat microbial flora in smokers with or without COPD

(2017) Wenqi Diao et al.   International Journal of Chronic Obstructive Pulmonary Disease

Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome

(2017) Marion Engel et al.   PLoS One

Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase

(2016) Joshua D. Deschamps et al.   BIOCHEMISTRY

Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease and cancer

(2016) R B Birge et al.   CELL DEATH AND DIFFERENTIATION

DHA- and EPA-derived resolvins, protectins, and maresins in airway inflammation

(2016) Melody G. Duvall et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Lung microbiome dynamics in COPD exacerbations

(2016) Zhang Wang et al.   EUROPEAN RESPIRATORY JOURNAL

Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids

(2016) Lisette I.Z. Kunz et al.   EUROPEAN RESPIRATORY JOURNAL

Phagocytosis: An Immunobiologic Process

(2016) Siamon Gordon   IMMUNITY

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

(2016) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A small volume technique to examine and compare alveolar macrophage phagocytosis of apoptotic cells and non typeable Haemophilus influenzae (NTHi)

(2016) Miranda Ween et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Differential lipid metabolism in monocytes and macrophages: influence of cholesterol loading

(2016) Irene Fernandez-Ruiz et al.   JOURNAL OF LIPID RESEARCH

The respiratory tract microbiome and lung inflammation: a two-way street

(2016) G B Huffnagle et al.   Mucosal Immunology

Acute exacerbation of COPD

(2016) Fanny W. Ko et al.   RESPIROLOGY

COPD is characterized by increased detection ofHaemophilus influenzae,Streptococcus pneumoniaeand a deficiency ofBacillusspecies

(2016) Jodie L. Simpson et al.   RESPIROLOGY

Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells

(2016) Mulki Angela et al.   Nature Communications

Resolvin D1 prevents smoking-induced emphysema and promotes lung tissue regeneration

(2016) Sei Won Lee et al.   International Journal of Chronic Obstructive Pulmonary Disease

Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype

(2016) Leopoldo N. Segal et al.   Nature Microbiology

Resolvins Attenuate Inflammation and Promote Resolution in Cigarette Smoke-Exposed Human Macrophages

(2015) Amanda Croasdell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pseudomonas aeruginosa Pyocyanin Induces Neutrophil Death via Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase

(2015) Antonella Managò et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of lipid microdomains in TLR-mediated signalling

(2015) Jean-Marie Ruysschaert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Signaling network of lipids as a comprehensive scaffold for omics data integration in sputum of COPD patients

(2015) Sadegh Azimzadeh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Ceramide and sphingosine in pulmonary infections

(2015) Aaron P. Seitz et al.   BIOLOGICAL CHEMISTRY

Klebsiella pneumoniaesurvives within macrophages by avoiding delivery to lysosomes

(2015) Victoria Cano et al.   CELLULAR MICROBIOLOGY

Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice

(2015) Mathieu C. Morissette et al.   EUROPEAN RESPIRATORY JOURNAL

Caveolin-1 aggravates cigarette smoke extract-induced MUC5AC secretion in human airway epithelial cells

(2015) QIAO YU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

How Bacterial Pathogens Eat Host Lipids: Implications for the Development of Fatty Acid Synthesis Therapeutics

(2015) Jiangwei Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways

(2015) Elena Izquierdo et al.   JOURNAL OF IMMUNOLOGY

The implication of cigarette smoking and cessation on macrophage cholesterol efflux in coronary artery disease patients

(2015) Wei Song et al.   JOURNAL OF LIPID RESEARCH

Role of Sphingolipids in the Pathobiology of Lung Inflammation

(2015) Riccardo Ghidoni et al.   MEDIATORS OF INFLAMMATION

Application of a Neutral Community Model To Assess Structuring of the Human Lung Microbiome

(2015) Arvind Venkataraman et al.   mBio

Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals

(2015) Christine M. Bassis et al.   mBio

The effect of statins on chronic obstructive pulmonary disease exacerbation and mortality: a systematic review and meta-analysis of observational research

(2015) Chao Cao et al.   Scientific Reports

Untargeted Lipidomic Analysis in Chronic Obstructive Pulmonary Disease. Uncovering Sphingolipids

(2014) Eef D. Telenga et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Severity-Related Changes of Bronchial Microbiome in Chronic Obstructive Pulmonary Disease

(2014) M. Garcia-Nunez et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Airway Microbiome Dynamics in Exacerbations of Chronic Obstructive Pulmonary Disease

(2014) Y. J. Huang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Acid Sphingomyelinase Amplifies Redox Signaling in Pseudomonas aeruginosa-Induced Macrophage Apoptosis

(2014) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Rapid Appearance of Resolvin Precursors in Inflammatory Exudates: Novel Mechanisms in Resolution

(2014) K. Kasuga et al.   JOURNAL OF IMMUNOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Blocking Phosphatidylcholine Utilization in Pseudomonas aeruginosa, via Mutagenesis of Fatty Acid, Glycerol and Choline Degradation Pathways, Confirms the Importance of This Nutrient Source In Vivo

(2014) Zhenxin Sun et al.   PLoS One

The Impact of Simvastatin on Pulmonary Effectors of Pseudomonas aeruginosa Infection

(2014) Emma Hennessy et al.   PLoS One

Sputum Eicosanoid Profiling in Exacerbations of Chronic Obstructive Pulmonary Disease

(2014) Orsolya Drozdovszky et al.   RESPIRATION

Statin use and exacerbations in individuals with chronic obstructive pulmonary disease

(2014) Truls S Ingebrigtsen et al.   THORAX

Bacterial microbiome of lungs in COPD

(2014) Don Sin et al.   International Journal of Chronic Obstructive Pulmonary Disease

Acid sphingomyelinase plays a key role in palmitic acid-amplified inflammatory signaling triggered by lipopolysaccharide at low concentrations in macrophages

(2013) Junfei Jin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Outgrowth of the Bacterial Airway Microbiome after Rhinovirus Exacerbation of Chronic Obstructive Pulmonary Disease

(2013) Philip L. Molyneaux et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of the Respiratory Microbiome in Healthy Nonsmokers and Smokers

(2013) Alison Morris et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lipid-Based Signaling Modulates DNA Repair Response and Survival againstKlebsiella pneumoniaeInfection in Host Cells and in Mice

(2013) Huang Huang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

COPD

(2013) Jørgen Vestbo   CLINICS IN CHEST MEDICINE

Phagocytic Dysfunction of Human Alveolar Macrophages and Severity of Chronic Obstructive Pulmonary Disease

(2013) Charles S. Berenson et al.   JOURNAL OF INFECTIOUS DISEASES

ABC-cassette transporter 1 (ABCA1) expression in epithelial cells in Chlamydia pneumoniae infection

(2013) Juha T. Korhonen et al.   MICROBIAL PATHOGENESIS

A Novel Anti-Inflammatory and Pro-Resolving Role for Resolvin D1 in Acute Cigarette Smoke-Induced Lung Inflammation

(2013) Hsi-Min Hsiao et al.   PLoS One

Elucidating the Pseudomonas aeruginosa Fatty Acid Degradation Pathway: Identification of Additional Fatty Acyl-CoA Synthetase Homologues

(2013) Jan Zarzycki-Siek et al.   PLoS One

Statins Decrease Lung Inflammation in Mice by Upregulating Tetraspanin CD9 in Macrophages

(2013) Yingji Jin et al.   PLoS One

n-3 Fatty acids, inflammation and immunity: new mechanisms to explain old actions

(2013) Philip C. Calder   PROCEEDINGS OF THE NUTRITION SOCIETY

Inhaled corticosteroids in COPD and the risk of serious pneumonia

(2013) Samy Suissa et al.   THORAX

Salmonella Uses Energy Taxis to Benefit from Intestinal Inflammation

(2013) Fabian Rivera-Chávez et al.   PLoS Pathogens

How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains

(2013) Jacques Fantini et al.   Frontiers in Physiology

Update on the potential role of statins in chronic obstructive pulmonary disease and its co-morbidities

(2013) Robert P Young et al.   Expert Review of Respiratory Medicine

The role of the bacterial microbiome in lung disease

(2013) Robert P Dickson et al.   Expert Review of Respiratory Medicine

Enrichment of lung microbiome with supraglottic taxa is associated with increased pulmonary inflammation

(2013) Leopoldo N Segal et al.   Microbiome

Vulnerability, beliefs, treatments and economic burden of chronic obstructive pulmonary disease in rural areas in China: a cross-sectional study

(2012) Peian Lou et al.   BMC PUBLIC HEALTH

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

Role of Sphingomyelinase in Infectious Diseases Caused by Bacillus cereus

(2012) Masataka Oda et al.   PLoS One

Assessing Bacterial Populations in the Lung by Replicate Analysis of Samples from the Upper and Lower Respiratory Tracts

(2012) Emily S. Charlson et al.   PLoS One

Serum amyloid A opposes lipoxin A4 to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

(2012) S. Bozinovski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ceramide Expression and Cell Homeostasis in Chronic Obstructive Pulmonary Disease

(2012) Maria C. Scarpa et al.   RESPIRATION

Profile of eicosanoids in breath condensate in asthma and COPD

(2012) Leandro Genehr Fritscher et al.   Journal of Breath Research

Antibacterial activity of statins: a comparative study of Atorvastatin, Simvastatin, and Rosuvastatin

(2012) Majed Masadeh et al.   Annals of Clinical Microbiology and Antimicrobials

Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract

(2011) Emily S. Charlson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Prostaglandins and Inflammation

(2011) Emanuela Ricciotti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Specific inhibitions of annonaceous acetogenins on class II 3-hydroxy-3-methylglutaryl coenzyme A reductase from Streptococcus pneumoniae

(2011) Lingling Feng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease

(2011) Jesper Z. Haeggström et al.   CHEMICAL REVIEWS

Lipid Mediator Profiling in Pulmonary Disease

(2011) Susanna L. Lundstrom et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Spatial distribution of microbial communities in the cystic fibrosis lung

(2011) Dana Willner et al.   ISME Journal

Interleukin-6 Protects Human Macrophages from Cellular Cholesterol Accumulation and Attenuates the Proinflammatory Response

(2011) Eric Frisdal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated Inflammatory Response in Caveolin-1-deficient Mice withPseudomonas aeruginosaInfection Is Mediated by STAT3 Protein and Nuclear Factor κB (NF-κB)

(2011) Kefei Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD

(2011) Jordi de Batlle et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Analysis of the Lung Microbiome in the “Healthy” Smoker and in COPD

(2011) John R. Erb-Downward et al.   PLoS One

Caveolin-1: a critical regulator of lung injury

(2010) Yang Jin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

ATP-binding Cassette Transporter G1 Deficiency Dysregulates Host Defense in the Lung

(2010) David W. Draper et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ceramide and activated Bax act synergistically to permeabilize the mitochondrial outer membrane

(2010) Vidyaramanan Ganesan et al.   APOPTOSIS

Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells

(2010) Viveka Schaar et al.   CELLULAR MICROBIOLOGY

Sphingolipid-mediated Inhibition of Apoptotic Cell Clearance by Alveolar Macrophages

(2010) Daniela N. Petrusca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dyslipidemia Induces Opposing Effects on Intrapulmonary and Extrapulmonary Host Defense through Divergent TLR Response Phenotypes

(2010) J. H. Madenspacher et al.   JOURNAL OF IMMUNOLOGY

Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol

(2010) Xuewei Zhu et al.   JOURNAL OF LIPID RESEARCH

Revitalizing membrane rafts: new tools and insights

(2010) Kai Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Disordered Microbial Communities in Asthmatic Airways

(2010) Markus Hilty et al.   PLoS One

Predicting early mortality in acute exacerbation of chronic obstructive pulmonary disease using the CURB65 score

(2010) Catherina L. CHANG et al.   RESPIROLOGY

Exploring the caves: cavins, caveolins and caveolae

(2010) Carsten G. Hansen et al.   TRENDS IN CELL BIOLOGY

Size and Dynamics of Caveolae Studied Using Nanoparticles in Living Endothelial Cells

(2009) Zhenjia Wang et al.   ACS Nano

Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa

(2009) Milan Bajmoczi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

ABCA1 modulates the oligomerization and Golgi exit of caveolin-1 during HDL-mediated cholesterol efflux in aortic endothelial cells

(2009) Yu-Chun Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity

(2009) André Kleinridders et al.   Cell Metabolism

Inflammation Impairs Reverse Cholesterol Transport In Vivo

(2009) Fiona C. McGillicuddy et al.   CIRCULATION

Defective macrophage phagocytosis of bacteria in COPD

(2009) A. E. Taylor et al.   EUROPEAN RESPIRATORY JOURNAL

Functional implications of the influence of ABCA1 on lipid microenvironment at the plasma membrane: a biophysical study

(2009) Ana Zarubica et al.   FASEB JOURNAL

Pseudomonas aeruginosa Rugose Small-Colony Variants Have Adaptations That Likely Promote Persistence in the Cystic Fibrosis Lung

(2009) M. Starkey et al.   JOURNAL OF BACTERIOLOGY

Caveolin-1 Modifies the Immunity to Pseudomonas aeruginosa

(2009) Mihaela Gadjeva et al.   JOURNAL OF IMMUNOLOGY

Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages

(2009) Hadi Sarir et al.   Journal of Inflammation-London

Smoking Is Associated with Shortened Airway Cilia

(2009) Philip L. Leopold et al.   PLoS One

Long-Distance Delivery of Bacterial Virulence Factors by Pseudomonas aeruginosa Outer Membrane Vesicles

(2009) Jennifer M. Bomberger et al.   PLoS Pathogens

Glucocorticoids shift arachidonic acid metabolism toward endocannabinoid synthesis: A non-genomic anti-inflammatory switch

(2008) Renato Malcher-Lopes et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Caveolae structure and function

(2008) Candice M. Thomas et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Membrane lipid homeostasis in bacteria

(2008) Yong-Mei Zhang et al.   NATURE REVIEWS MICROBIOLOGY

Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease

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