Maresins: Specialized Proresolving Lipid Mediators and Their Potential Role in Inflammatory-Related Diseases

Disruption of the Gut Ecosystem by Antibiotics

(2018) Mi Young Yoon et al.   YONSEI MEDICAL JOURNAL

Maresin 1 improves insulin sensitivity and attenuates adipose tissue inflammation in ob/ob and diet-induced obese mice

(2017) Leyre Martínez-Fernández et al.   FASEB JOURNAL

Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms

(2017) Charles N. Serhan   FASEB JOURNAL

Maresin 1 induces a novel pro-resolving phenotype in human platelets

(2017) K. L. Lannan et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Maresin 1 Mitigates High Glucose-Induced Mouse Glomerular Mesangial Cell Injury by Inhibiting Inflammation and Fibrosis

(2017) Shi Tang et al.   MEDIATORS OF INFLAMMATION

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration

(2017) Charles N. Serhan et al.   MOLECULAR ASPECTS OF MEDICINE

Maresin 1 Ameliorates Lung Ischemia/Reperfusion Injury by Suppressing Oxidative Stress via Activation of the Nrf-2-Mediated HO-1 Signaling Pathway

(2017) Quanchao Sun et al.   Oxidative Medicine and Cellular Longevity

Resolving Lipid Mediators Maresin 1 and Resolvin D2 Prevent Atheroprogression in Mice

(2016) Joana Viola et al.   CIRCULATION RESEARCH

Maresin 1 Maintains the Permeability of Lung Epithelial Cells In Vitro and In Vivo

(2016) Lin Chen et al.   INFLAMMATION

Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis

(2016) Ruidong Li et al.   MEDIATORS OF INFLAMMATION

Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

(2016) Jesmond Dalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Key mechanisms governing resolution of lung inflammation

(2016) C. T. Robb et al.   Seminars in Immunopathology

Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3

(2016) Jesmond Dalli et al.   PLoS One

The soluble interleukin-6 receptor and related proteins

(2015) Stefan Rose-John   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

(2015) Charles N. Serhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Systemic delivery of proresolving lipid mediators resolvin D2 and maresin 1 attenuates intimal hyperplasia in mice

(2015) Daisuke Akagi et al.   FASEB JOURNAL

IL-6 as a keystone cytokine in health and disease

(2015) Christopher A Hunter et al.   NATURE IMMUNOLOGY

The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution

(2015) Charles N. Serhan et al.   SEMINARS IN IMMUNOLOGY

Maresin 1 Inhibits Epithelial-to-Mesenchymal Transition in Vitro and Attenuates Bleomycin Induced Lung Fibrosis in Vivo

(2015) Yaxin Wang et al.   SHOCK

Stereoselective synthesis of maresin 1

(2015) Jørn E. Tungen et al.   TETRAHEDRON LETTERS

First total synthesis of the macrophage derived anti-inflammatory and pro-resolving lipid mediator Maresin 2

(2015) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

First total synthesis of pro-resolving and tissue-regenerative Maresin sulfido-conjugates

(2015) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Maresin-1 reduces airway inflammation associated with acute and repetitive exposures to organic dust

(2015) Tara M. Nordgren et al.   Translational Research

Maresin 1 mitigates LPS-induced acute lung injury in mice

(2014) Jie Gong et al.   BRITISH JOURNAL OF PHARMACOLOGY

Maresin-like Lipid Mediators Are Produced by Leukocytes and Platelets and Rescue Reparative Function of Diabetes-Impaired Macrophages

(2014) Song Hong et al.   CHEMISTRY & BIOLOGY

Combination Therapy of 15-Epi-Lipoxin A4 With Antibiotics Protects Mice From Escherichia coli–Induced Sepsis*

(2014) Tomomi Ueda et al.   CRITICAL CARE MEDICINE

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Cutting Edge: Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of Lung Inflammation

(2014) Nandini Krishnamoorthy et al.   JOURNAL OF IMMUNOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages

(2014) Bin Deng et al.   PLoS One

The Pro-Resolving Lipid Mediator Maresin 1 (MaR1) Attenuates Inflammatory Signaling Pathways in Vascular Smooth Muscle and Endothelial Cells

(2014) Anuran Chatterjee et al.   PLoS One

Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection

(2014) J. Dalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

(2013) Matthew Spite et al.   Cell Metabolism

The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype

(2013) Jesmond Dalli et al.   FASEB JOURNAL

Plasticity of Leukocytic Exudates in Resolving Acute Inflammation Is Regulated by MicroRNA and Proresolving Mediators

(2013) Yongsheng Li et al.   IMMUNITY

Maresin 1, a Proresolving Lipid Mediator Derived from Omega-3 Polyunsaturated Fatty Acids, Exerts Protective Actions in Murine Models of Colitis

(2013) R. Marcon et al.   JOURNAL OF IMMUNOLOGY

Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust

(2013) Tara M Nordgren et al.   RESPIRATORY RESEARCH

Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

(2012) Charles N. Serhan et al.   FASEB JOURNAL

Total synthesis of the macrophage derived anti-inflammatory lipid mediator Maresin 1

(2012) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

Total Synthesis and Bioactivities of Two Proposed Structures of Maresin

(2010) Kenji Sasaki et al.   Chemistry-An Asian Journal

Resolvins and protectins: mediating solutions to inflammation

(2009) Payal Kohli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE