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Title
Metabolic Modulation in Macrophage Effector Function
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-02-19
DOI
10.3389/fimmu.2018.00270
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Note: Only part of the references are listed.- Cellular metabolism of tumor-associated macrophages - functional impact and consequences
- (2017) Katrin Rabold et al. FEBS LETTERS
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- (2017) Zbigniew Zasłona et al. JOURNAL OF IMMUNOLOGY
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- (2017) Sofia Pavlou et al. Journal of Inflammation-London
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- (2017) Sheng Hui et al. NATURE
- Differential Regulation of Macrophage Glucose Metabolism by Macrophage Colony-stimulating Factor and Granulocyte-Macrophage Colony-stimulating Factor: Implications for 18F FDG PET Imaging of Vessel Wall Inflammation
- (2017) Sina Tavakoli et al. RADIOLOGY
- Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages
- (2017) W. K. Eddie Ip et al. SCIENCE
- BCAT1 controls metabolic reprogramming in activated human macrophages and is associated with inflammatory diseases
- (2017) Adonia E. Papathanassiu et al. Nature Communications
- Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis
- (2017) Lingli Hu et al. Frontiers in Immunology
- Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors
- (2017) Eva M. Palsson-McDermott et al. Frontiers in Immunology
- Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity
- (2017) Paulo C. Rodriguez et al. Frontiers in Immunology
- GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice
- (2016) T. Rubić-Schneider et al. ALLERGY
- miR-125b controls monocyte adaptation to inflammation through mitochondrial metabolism and dynamics
- (2016) I. Duroux-Richard et al. BLOOD
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
- (2016) Evanna L. Mills et al. CELL
- Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan
- (2016) Andrea J. Wolf et al. CELL
- Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
- (2016) Mathias Wenes et al. Cell Metabolism
- Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan
- (2016) Filippo Scialò et al. Cell Metabolism
- Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
- (2016) Vicky Lampropoulou et al. Cell Metabolism
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity
- (2016) Rob J.W. Arts et al. Cell Metabolism
- Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage
- (2016) Beáta Németh et al. FASEB JOURNAL
- K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria
- (2016) Christina J. Groß et al. IMMUNITY
- Targeting T Cell Co-receptors for Cancer Therapy
- (2016) Margaret K. Callahan et al. IMMUNITY
- Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation
- (2016) Stanley Ching-Cheng Huang et al. IMMUNITY
- Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels
- (2016) Thekla Cordes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis
- (2016) Amanda Littlewood-Evans et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease
- (2016) Tsuyoshi Shirai et al. JOURNAL OF EXPERIMENTAL MEDICINE
- GAPDH Binding to TNF-α mRNA Contributes to Posttranscriptional Repression in Monocytes: A Novel Mechanism of Communication between Inflammation and Metabolism
- (2016) Patrick Millet et al. JOURNAL OF IMMUNOLOGY
- Comprehensive Proteomics Analysis Reveals Metabolic Reprogramming of Tumor-Associated Macrophages Stimulated by the Tumor Microenvironment
- (2016) Di Liu et al. JOURNAL OF PROTEOME RESEARCH
- Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
- (2016) Shih-Chin Cheng et al. NATURE IMMUNOLOGY
- Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense
- (2016) Johan Garaude et al. NATURE IMMUNOLOGY
- Fatty acid oxidation in macrophage polarization
- (2016) Mitsunori Nomura et al. NATURE IMMUNOLOGY
- C13orf31 (FAMIN) is a central regulator of immunometabolic function
- (2016) M Zaeem Cader et al. NATURE IMMUNOLOGY
- NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages
- (2016) Jong-Seok Moon et al. NATURE MEDICINE
- HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity
- (2016) Hiroaki Semba et al. Nature Communications
- PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
- (2016) Min Xie et al. Nature Communications
- Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages
- (2016) Jan Van den Bossche et al. Cell Reports
- IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid
- (2016) Jan Naujoks et al. PLoS Pathogens
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- (2016) Anthony J Covarrubias et al. eLife
- Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma
- (2016) Hweixian Leong Penny et al. OncoImmunology
- Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production
- (2016) Walter A. Baseler et al. Redox Biology
- Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation
- (2015) Maria Ida Malandrino et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling
- (2015) M. Carmen Fernández-Agüera et al. Cell Metabolism
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- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
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- (2015) Peter J Murray NATURE IMMUNOLOGY
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- (2014) Vittoria Infantino et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- ROS-Triggered Phosphorylation of Complex II by Fgr Kinase Regulates Cellular Adaptation to Fuel Use
- (2014) Rebeca Acín-Pérez et al. Cell Metabolism
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
- (2014) Jia Xue et al. IMMUNITY
- Metabolic Reprogramming of Macrophages
- (2014) Alex J. Freemerman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysine Malonylation Is Elevated in Type 2 Diabetic Mouse Models and Enriched in Metabolic Associated Proteins
- (2014) Yipeng Du et al. MOLECULAR & CELLULAR PROTEOMICS
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
- (2014) Edward T. Chouchani et al. NATURE
- Bacterial itaconate degradation promotes pathogenicity
- (2014) Jahminy Sasikaran et al. Nature Chemical Biology
- Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity
- (2014) S.-C. Cheng et al. SCIENCE
- Microtubule acetylation amplifies p38 kinase signalling and anti-inflammatory IL-10 production
- (2014) Bin Wang et al. Nature Communications
- PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis
- (2014) Liangchun Yang et al. Nature Communications
- Mitochondrial Respiratory Supercomplex Association Limits Production of Reactive Oxygen Species from Complex I
- (2013) Evelina Maranzana et al. ANTIOXIDANTS & REDOX SIGNALING
- ATP-citrate lyase is essential for macrophage inflammatory response
- (2013) Vittoria Infantino et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
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- (2013) Christopher J. Hall et al. Cell Metabolism
- NLRP3 and IL-1βin macrophages as critical regulators of metabolic diseases
- (2013) A. F. McGettrick et al. DIABETES OBESITY & METABOLISM
- Asymmetric dimethylarginine regulates the lipopolysaccharide-induced nitric oxide production in macrophages by suppressing the activation of NF-kappaB and iNOS expression
- (2013) Michaela Pekarova et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species
- (2013) Yingke Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
- (2013) A. Michelucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain
- (2013) E. Lapuente-Brun et al. SCIENCE
- Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infection
- (2013) Yegnasew Takele et al. PLoS Neglected Tropical Diseases
- Regulation of Immune Responses by mTOR
- (2012) Jonathan D. Powell et al. Annual Review of Immunology
- The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
- (2012) Arvand Haschemi et al. Cell Metabolism
- Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
- (2012) Paul D. Ray et al. CELLULAR SIGNALLING
- The unique role of dietary l-arginine in the acceleration of peritoneal macrophage sensitivity to bacterial endotoxin
- (2012) Michaela Pekarova et al. IMMUNOLOGIC RESEARCH
- Amino acid catabolism: a pivotal regulator of innate and adaptive immunity
- (2012) Tracy L. McGaha et al. IMMUNOLOGICAL REVIEWS
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- (2012) S. Bae et al. JOURNAL OF IMMUNOLOGY
- Mechanisms of triglyceride accumulation in activated macrophages
- (2012) Kenneth R. Feingold et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Heterotrimeric GAIT Complex Drives Transcript-Selective Translation Inhibition in Murine Macrophages
- (2012) A. Arif et al. MOLECULAR AND CELLULAR BIOLOGY
- Novel role of PKR in inflammasome activation and HMGB1 release
- (2012) Ben Lu et al. NATURE
- The mitochondrial citrate carrier: a new player in inflammation
- (2011) Vittoria Infantino et al. BIOCHEMICAL JOURNAL
- Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
- (2011) Ariel C. Bulua et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Arginine transport in human monocytic leukemia THP-1 cells during macrophage differentiation
- (2011) Amelia Barilli et al. JOURNAL OF LEUKOCYTE BIOLOGY
- 1H NMR-based Metabolomic Profiling in Mice Infected withMycobacterium tuberculosis
- (2011) Ji-Hyun Shin et al. JOURNAL OF PROTEOME RESEARCH
- Itaconic Acid Is a Mammalian Metabolite Induced during Macrophage Activation
- (2011) Cheryl L. Strelko et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Non-targeted metabolite profiling in activated macrophage secretion
- (2011) Masahiro Sugimoto et al. Metabolomics
- The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme
- (2011) Chao Peng et al. MOLECULAR & CELLULAR PROTEOMICS
- TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
- (2011) A. Phillip West et al. NATURE
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- New Role for L-Arginine in Regulation of Inducible Nitric-Oxide-Synthase-Derived Superoxide Anion Production in Raw 264.7 Macrophages
- (2011) Michaela Pekarova et al. TheScientificWorldJOURNAL
- Differential activation and antagonistic function of HIF- isoforms in macrophages are essential for NO homeostasis
- (2010) N. Takeda et al. GENES & DEVELOPMENT
- Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation
- (2010) J.-C. Rodriguez-Prados et al. JOURNAL OF IMMUNOLOGY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation
- (2010) Kristiina Rajamäki et al. PLoS One
- The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1
- (2009) Paul G. Thomas et al. IMMUNITY
- Translational repression of inducible NO synthase in macrophages by l-arginine depletion is not associated with an increased phosphorylation of eIF2α
- (2009) Till König et al. IMMUNOBIOLOGY
- Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome
- (2009) Joseph A. Duncan et al. JOURNAL OF IMMUNOLOGY
- Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis
- (2009) John T. Pesce et al. PLoS Pathogens
- The Proinflammatory Cytokine-Induced IRG1 Protein Associates with Mitochondria
- (2008) Daniel Degrandi et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
- (2008) Jordi Rius et al. NATURE
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