Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions

Health Care Industry Insights: Why the Use of Preventive Services Is Still Low

(2019) Susan Levine et al.   Preventing Chronic Disease

A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis

(2019) Yong-Hyun Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolving inflammation in nonalcoholic steatohepatitis

(2019) Matthew Spite   JOURNAL OF CLINICAL INVESTIGATION

Prostaglandin E2 suppresses hCAP18/LL-37 expression in human macrophages via EP2/EP4: implications for treatment of Mycobacterium tuberculosis infection

(2018) Min Wan et al.   FASEB JOURNAL

New maresin conjugates in tissue regeneration pathway counters leukotriene D4–stimulated vascular responses

(2018) Nan Chiang et al.   FASEB JOURNAL

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

(2018) Sangsu Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6

(2018) Emmanuelle Szenker-Ravi et al.   NATURE

Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders

(2018) T. Yang et al.   BRITISH JOURNAL OF ANAESTHESIA

DELineating resolution of inflammation

(2018) Gabrielle Fredman   NATURE IMMUNOLOGY

Maresin 1 Promotes Inflammatory Resolution, Neuroprotection, and Functional Neurological Recovery After Spinal Cord Injury

(2017) Isaac Francos-Quijorna et al.   JOURNAL OF NEUROSCIENCE

Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors

(2017) Nan Chiang et al.   MOLECULAR ASPECTS OF MEDICINE

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration

(2017) Charles N. Serhan et al.   MOLECULAR ASPECTS OF MEDICINE

Prediction of potent shRNAs with a sequential classification algorithm

(2017) Raphael Pelossof et al.   NATURE BIOTECHNOLOGY

Immune resolution mechanisms in inflammatory arthritis

(2017) Mauro Perretti et al.   Nature Reviews Rheumatology

A cluster of immunoresolvents links coagulation to innate host defense in human blood

(2017) Paul C. Norris et al.   Science Signaling

A cluster of immunoresolvents links coagulation to innate host defense in human blood

(2017) Paul C. Norris et al.   Science Signaling

Divergent shifts in lipid mediator profile following supplementation with n-3 docosapentaenoic acid and eicosapentaenoic acid

(2016) James F. Markworth et al.   FASEB JOURNAL

The immune system's role in sepsis progression, resolution, and long-term outcome

(2016) Matthew J. Delano et al.   IMMUNOLOGICAL REVIEWS

Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation

(2016) Romain A. Colas et al.   JOURNAL OF IMMUNOLOGY

Specialised pro-resolving mediators of inflammation in inflammatory arthritis

(2016) Anne E. Barden et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

(2015) Charles N. Serhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis

(2015) Mingqin Zhu et al.   MOLECULAR NEUROBIOLOGY

Lgr6 marks nail stem cells and is required for digit tip regeneration

(2015) Jessica A. Lehoczky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gaseous mediators in resolution of inflammation

(2015) John L. Wallace et al.   SEMINARS IN IMMUNOLOGY

Maresin-1 reduces airway inflammation associated with acute and repetitive exposures to organic dust

(2015) Tara M. Nordgren et al.   Translational Research

Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins

(2015) Eleonora Cianci et al.   Stem Cells Translational Medicine

Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages

(2014) Bin Deng et al.   PLoS One

Single-cell mass cytometry of TCR signaling: Amplification of small initial differences results in low ERK activation in NOD mice

(2014) Michael Mingueneau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single Lgr5- or Lgr6-expressing taste stem/progenitor cells generate taste bud cells ex vivo

(2014) Wenwen Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity of lipid mediators in human adipose tissue depots

(2013) Joan Clària et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An Optimized microRNA Backbone for Effective Single-Copy RNAi

(2013) Christof Fellmann et al.   Cell Reports

Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

(2012) Charles N. Serhan et al.   FASEB JOURNAL

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

LGR6 Is a High Affinity Receptor of R-Spondins and Potentially Functions as a Tumor Suppressor

(2012) Xing Gong et al.   PLoS One

Total synthesis of the macrophage derived anti-inflammatory lipid mediator Maresin 1

(2012) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

International Union of Basic and Clinical Pharmacology. LXXXIII: Classification of Prostanoid Receptors, Updating 15 Years of Progress

(2011) D. F. Woodward et al.   PHARMACOLOGICAL REVIEWS

The Role of the Transcription Factor CREB in Immune Function

(2010) A. Y. Wen et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

(2010) S. Krishnamoorthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

(2010) H. J. Snippert et al.   SCIENCE

Lipid Mediators in Health and Disease: Enzymes and Receptors as Therapeutic Targets for the Regulation of Immunity and Inflammation

(2008) Takao Shimizu   Annual Review of Pharmacology and Toxicology

Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP

(2008) J. Bystrom et al.   BLOOD

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE