TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema

Cytotoxic and cytostatic effects of four Annonaceae plants on human cancer cell lines

(2019) Kitti Pumiputavon et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Novel mechanisms regulating endothelial barrier function in the pulmonary microcirculation

(2018) Szandor Simmons et al.   JOURNAL OF PHYSIOLOGY-LONDON

TRPA1 channels: expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia

(2018) Martina Kannler et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

TRPs in Tox: Involvement of Transient Receptor Potential-Channels in Chemical-Induced Organ Toxicity—A Structured Review

(2018) Dirk Steinritz et al.   Cells

TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells

(2017) Yeranddy A. Alpizar et al.   Nature Communications

Nitric Oxide–Dependent Feedback Loop Regulates Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Cooperativity and Endothelial Function in Small Pulmonary Arteries

(2017) Corina Marziano et al.   Journal of the American Heart Association

In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium: Potential involvement in cystic fibrosis

(2016) Clémence O. Henry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TRPV4 Regulates Tight Junctions and Affects Differentiation in a Cell Culture Model of the Corneal Epithelium

(2016) Jacqueline Martínez-Rendón et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4

(2015) Karthik Suresh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

On the Tricks Alveolar Epithelial Cells Play to Make a Good Lung

(2015) Ewald R. Weibel   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction

(2015) Neil M. Goldenberg et al.   ANESTHESIOLOGY

Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/ -catenin-driven trans-differentiation of murine alveolar epithelial cells

(2015) K. Mutze et al.   Disease Models & Mechanisms

Phospholipase C Epsilon (PLCε) Induced TRPC6 Activation: A Common but Redundant Mechanism in Primary Podocytes

(2015) Hermann Kalwa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury

(2014) Shrilatha Balakrishna et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD

(2014) Gerrit John-Schuster et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice

(2014) Shaik O. Rahaman et al.   JOURNAL OF CLINICAL INVESTIGATION

Alveolar progenitor and stem cells in lung development, renewal and cancer

(2014) Tushar J. Desai et al.   NATURE

TRPV4: physiological role and therapeutic potential in respiratory diseases

(2014) Neil M. Goldenberg et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Down-regulated aquaporin 5 inhibits proliferation and migration of human epithelial ovarian cancer 3AO cells

(2014) ChunXiao Yan et al.   Journal of Ovarian Research

TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension

(2013) Yang Xia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure

(2012) Kevin S. Thorneloe et al.   Science Translational Medicine

Activation of TRPV4 Strengthens the Tight-Junction Barrier in Human Epidermal Keratinocytes

(2012) Y. Akazawa et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Reduced migration of Ishikawa cells associated with downregulation of aquaporin-5

(2012) XIU XIU JIANG et al.   Oncology Letters

Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice

(2012) Norbert Weissmann et al.   Nature Communications

TRPV4-Mediated Calcium Influx into Human Bronchial Epithelia upon Exposure to Diesel Exhaust Particles

(2011) Jinju Li et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Ion Transport by Pulmonary Epithelia

(2011) Monika I. Hollenhorst et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

(2010) W. Everaerts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress

(2009) Suelhem A. Mendoza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Great Big Alveolar TI Cell: Evolving Concepts and Paradigms

(2009) Leland Dobbs et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Negative-Feedback Loop Attenuates Hydrostatic Lung Edema via a cGMP-Dependent Regulation of Transient Receptor Potential Vanilloid 4

(2008) Jun Yin et al.   CIRCULATION RESEARCH

TRPP2 and TRPV4 form a polymodal sensory channel complex

(2008) Michael Köttgen et al.   JOURNAL OF CELL BIOLOGY

Surfactants: past, present and future

(2008) H L Halliday   Journal of Perinatology

TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells

(2008) I. M. Lorenzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Vascular Pressure–Induced Lung Injury Requires P450 Epoxygenase–Dependent Activation of TRPV4

(2007) Ming-Yuan Jian et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY